Gene Detail
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| Gene Symbol | PATZ1 | ||||||||||
| Synonyms | dJ400N23 | MAZR | PATZ | RIAZ | ZBTB19 | ZNF278 | ZSG | ||||||||||
| Gene Description | PATZ1, POZ/BTB and AT hook containing zinc finger 1, encodes a transcription factor that can act as either an activator or repressor and is linked to P53 regulation (PMID: 24336083) and may regulate the development of regulatory T-cells (PMID: 31875552). Overexpression of Patz1 has been associated with a number of cancer types (PMID: 18401526, PMID: 18241078), including pediatric glioma (PMID: 31614588) and an EWSR1-PATZ1 fusion has been identified in Ewing sarcoma (PMID: 10949935), glioneuronal tumor (PMID: 29679497), gangliogliomas (PMID: 26810070), and round cell sarcoma (PMID: 32134119, PMID: 31189996). | ||||||||||
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