Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol IFIT2
Synonyms cig42 | G10P2 | GARG-39 | IFI-54 | IFI-54K | IFI54 | IFIT-2 | ISG-54 | ISG-54 K | ISG-54K | ISG54 | P54
Gene Description IFIT2, interferon-induced protein with tetratricopeptide repeats 2, is a member of the IRF-inducible gene family that plays a role in the immune defense against RNA viruses and promotes apoptosis (PMID: 30234477, PMID: 31921891). Decreased expression of Ifit2 in gastric cancer and non-small cell lung cancer has been associated with tumor progression and poor prognosis (PMID: 29316541, PMID: 31632065).
Additional content available in CKB BOOST