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Gene Symbol KIF5B
Synonyms HEL-S-61 | KINH | KNS | KNS1 | UKHC
Gene Description KIF5B, kinesin family member 5B, is a microtubule motor protein involved in cargo transportation (PMID: 12743033), including lysosome and mitochondria transportation (PMID: 30058692). KIF5B fusions with RET (PMID: 22327624, PMID: 32094155), MET (PMID: 29284707), and ALK (PMID: 21656749, PMID: 21757253) have been frequently identified in lung cancer (PMID: 22327623), and Kif5b expression has been associated with poor prognosis in oral squamous cell carcinoma (PMID: 30058692).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
3799 10 10p11.22 NM_004521 Unknown
Additional content available in CKB BOOST