Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol SSRP1
Synonyms FACT | FACT80 | T160
Gene Description SSRP1, structure specific recognition protein 1, is a histone chaperone and forms part of the facilitates chromatin transcription (FACT) complex to mediate DNA replication, DNA damage repair, apoptosis and cell cycle regulation (PMID: 29048646, PMID: 32165637). SSRP1 overexpression has been observed in glioma, where it may correlate with stage (PMID: 29048646), and in breast cancer (PMID: 28496363) and hepatocellular carcinoma (PMID: 26755331).
Additional content available in CKB BOOST