Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol CD40
Synonyms Bp50 | CDW40 | p50 | TNFRSF5
Gene Description CD40, CD40 molecule, encodes for a member of the tumor necrosis factor receptor family, which is expressed in a variety of cell types such as B cells, dendritic cells, monocytes, and platelets, and its signaling plays a role in multiple immune processes (PMID: 19426221). CD40 is expressed in many types of tumor cells, including breast, ovary, bladder, lung, colon, prostate, and melanoma (PMID: 11929824).
Additional content available in CKB BOOST