The Clinical Knowledgebase (CKB)

Powered by The Jackson Laboratory

CKB is a dynamic digital resource for interpreting complex cancer genomic profiles in the context of protein impact, therapies, and clinical trials. CKB CORE is the public access version we have been providing to the community since 2016. CKB CORE contains all the content associated with 50 genes that are commonly found on cancer hotspot panels. New and updated content is pushed out daily and viewable genes are available on a quarterly rotating schedule.

Check out   CKB BOOST for content extending to 1700+ genes.

Apr 9, 2021 - We made some updates to CKB CORE with a focus on delivering high level, thematic content! To find out more, check out our new quarterly newsletter by clicking here. Have questions or comments? Email us at

Mar 10, 2021 - New job posting! The CKB group is looking for people to join the team! Check it out here: Clinical Scientific Curator