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| NCT ID | NCT01835145 |
| Title | Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | United States | Details | |
| Anchorage Radiation Therapy Center | Anchorage | Alaska | 99504 | United States | Details | |
| Alaska Breast Care and Surgery LLC | Anchorage | Alaska | 99508 | United States | Details | |
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | United States | Details | |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | United States | Details | |
| Anchorage Oncology Centre | Anchorage | Alaska | 99508 | United States | Details | |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | United States | Details | |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | United States | Details | |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | United States | Details | |
| Beebe Medical Center | Lewes | Delaware | 19958 | United States | Details | |
| Christiana Gynecologic Oncology LLC | Newark | Delaware | 19713 | United States | Details | |
| Delaware Clinical and Laboratory Physicians PA | Newark | Delaware | 19713 | United States | Details | |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | United States | Details | |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | United States | Details | |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | United States | Details | |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | United States | Details | |
| TidalHealth Nanticoke / Allen Cancer Center | Seaford | Delaware | 19973 | United States | Details | |
| Christiana Care Health System-Wilmington Hospital | Wilmington | Delaware | 19801 | United States | Details | |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | United States | Details | |
| Jupiter Medical Center | Jupiter | Florida | 33458 | United States | Details | |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | United States | Details | |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | United States | Details | |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | United States | Details | |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | United States | Details | |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | United States | Details | |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83686 | United States | Details | |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | United States | Details | |
| Kootenai Cancer Clinic | Sandpoint | Idaho | 83864 | United States | Details | |
| Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | 83301 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60611 | United States | Details | |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | United States | Details | |
| Hematology Oncology Associates of Illinois-Highland Park | Highland Park | Illinois | 60035 | United States | Details | |
| Presence Saint Mary's Hospital | Kankakee | Illinois | 60901 | United States | Details | |
| AMG Libertyville - Oncology | Libertyville | Illinois | 60048 | United States | Details | |
| Loyola University Medical Center | Maywood | Illinois | 60153 | United States | Details | |
| Garneau, Stewart C MD (UIA Investigator) | Moline | Illinois | 61265 | United States | Details | |
| Porubcin, Michael MD (UIA Investigator) | Moline | Illinois | 61265 | United States | Details | |
| Spector, David MD (UIA Investigator) | Moline | Illinois | 61265 | United States | Details | |
| Trinity Medical Center | Moline | Illinois | 61265 | United States | Details | |
| Good Samaritan Regional Health Center | Mount Vernon | Illinois | 62864 | United States | Details | |
| Illinois Cancer Specialists-Niles | Niles | Illinois | 60714 | United States | Details | |
| Hematology Oncology Associates of Illinois - Skokie | Skokie | Illinois | 60076 | United States | Details | |
| Mary Greeley Medical Center | Ames | Iowa | 50010 | United States | Details | |
| McFarland Clinic PC - Ames | Ames | Iowa | 50010 | United States | Details | |
| Constantinou, Costas L MD (UIA Investigator) | Bettendorf | Iowa | 52722 | United States | Details | |
| McFarland Clinic PC-Boone | Boone | Iowa | 50036 | United States | Details | |
| McFarland Clinic PC-Trinity Cancer Center | Fort Dodge | Iowa | 50501 | United States | Details | |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | United States | Details | |
| McFarland Clinic PC-Jefferson | Jefferson | Iowa | 50129 | United States | Details | |
| McFarland Clinic PC-Marshalltown | Marshalltown | Iowa | 50158 | United States | Details | |
| Siouxland Regional Cancer Center | Sioux City | Iowa | 51101 | United States | Details | |
| Mercy Medical Center-Sioux City | Sioux City | Iowa | 51102 | United States | Details | |
| Saint Luke's Regional Medical Center | Sioux City | Iowa | 51104 | United States | Details | |
| Menorah Medical Center | Overland Park | Kansas | 66209 | United States | Details | |
| Saint Luke's South Hospital | Overland Park | Kansas | 66213 | United States | Details | |
| Kansas City NCI Community Oncology Research Program | Prairie Village | Kansas | 66208 | United States | Details | |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | United States | Details | |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | United States | Details | |
| Green Bay Oncology - Escanaba | Escanaba | Michigan | 49829 | United States | Details | |
| Cancer Research Consortium of West Michigan NCORP | Grand Rapids | Michigan | 49503 | United States | Details | |
| Mercy Health Saint Mary's | Grand Rapids | Michigan | 49503 | United States | Details | |
| Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | 49503 | United States | Details | |
| Green Bay Oncology - Iron Mountain | Iron Mountain | Michigan | 49801 | United States | Details | |
| Mercy Health Mercy Campus | Muskegon | Michigan | 49444 | United States | Details | |
| Lakeland Hospital Niles | Niles | Michigan | 49120 | United States | Details | |
| Spectrum Health Reed City Hospital | Reed City | Michigan | 49677 | United States | Details | |
| Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | 49085 | United States | Details | |
| Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | United States | Details | |
| Munson Medical Center | Traverse City | Michigan | 49684 | United States | Details | |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | United States | Details | |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | United States | Details | |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | United States | Details | |
| Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | 55805 | United States | Details | |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | United States | Details | |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | United States | Details | |
| Unity Hospital | Fridley | Minnesota | 55432 | United States | Details | |
| Hutchinson Area Health Care | Hutchinson | Minnesota | 55350 | United States | Details | |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | United States | Details | |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | United States | Details | |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | United States | Details | |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | United States | Details | |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | United States | Details | |
| New Ulm Medical Center | New Ulm | Minnesota | 56073 | United States | Details | |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | United States | Details | |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| Metro Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | United States | Details | |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | United States | Details | |
| Regions Hospital | Saint Paul | Minnesota | 55101 | United States | Details | |
| United Hospital | Saint Paul | Minnesota | 55102 | United States | Details | |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | United States | Details | |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | United States | Details | |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | United States | Details | |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | United States | Details | |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | United States | Details | |
| Cox Cancer Center Branson | Branson | Missouri | 65616 | United States | Details | |
| Centerpoint Medical Center LLC | Independence | Missouri | 64057 | United States | Details | |
| Mercy Hospital Joplin | Joplin | Missouri | 64804 | United States | Details | |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | United States | Details | |
| Heartland Hematology and Oncology Associates Incorporated | Kansas City | Missouri | 64118 | United States | Details | |
| Research Medical Center | Kansas City | Missouri | 64132 | United States | Details | |
| Saint Luke's East - Lee's Summit | Lee's Summit | Missouri | 64086 | United States | Details | |
| Liberty Radiation Oncology Center | Liberty | Missouri | 64068 | United States | Details | |
| Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | 65401 | United States | Details | |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | United States | Details | |
| Saint Joseph Oncology Inc | Saint Joseph | Missouri | 64507 | United States | Details | |
| Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri | 63109 | United States | Details | |
| Mercy Hospital Saint Louis | Saint Louis | Missouri | 63141 | United States | Details | |
| Cancer Research for the Ozarks NCORP | Springfield | Missouri | 65804 | United States | Details | |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | United States | Details | |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | United States | Details | |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | United States | Details | |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | United States | Details | |
| Saint Vincent Healthcare | Billings | Montana | 59101 | United States | Details | |
| Montana Cancer Consortium NCORP | Billings | Montana | 59102 | United States | Details | |
| Bozeman Deaconess Hospital | Bozeman | Montana | 59715 | United States | Details | |
| Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | 59701 | United States | Details | |
| Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | 59405 | United States | Details | |
| Great Falls Clinic | Great Falls | Montana | 59405 | United States | Details | |
| Saint Peter's Community Hospital | Helena | Montana | 59601 | United States | Details | |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | United States | Details | |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | United States | Details | |
| Community Medical Hospital | Missoula | Montana | 59804 | United States | Details | |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | United States | Details | |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | United States | Details | |
| Cancer and Blood Specialists-Henderson | Henderson | Nevada | 89052 | United States | Details | |
| Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | 89052 | United States | Details | |
| Las Vegas Cancer Center-Henderson | Henderson | Nevada | 89052 | United States | Details | |
| Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada | 89074 | United States | Details | |
| GenesisCare USA - Henderson | Henderson | Nevada | 89074 | United States | Details | |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | United States | Details | |
| Cancer and Blood Specialists-Shadow | Las Vegas | Nevada | 89106 | United States | Details | |
| Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | 89106 | United States | Details | |
| GenesisCare USA - Las Vegas | Las Vegas | Nevada | 89109 | United States | Details | |
| HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas | Nevada | 89109 | United States | Details | |
| HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas | Nevada | 89113 | United States | Details | |
| Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | 89119 | United States | Details | |
| Cancer Therapy and Integrative Medicine | Las Vegas | Nevada | 89121 | United States | Details | |
| Cancer and Blood Specialists-Tenaya | Las Vegas | Nevada | 89128 | United States | Details | |
| Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | 89128 | United States | Details | |
| GenesisCare USA - Vegas Tenaya | Las Vegas | Nevada | 89128 | United States | Details | |
| HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas | Nevada | 89128 | United States | Details | |
| Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | 89144 | United States | Details | |
| Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada | 89148-2405 | United States | Details | |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89148 | United States | Details | |
| GenesisCare USA - Fort Apache | Las Vegas | Nevada | 89148 | United States | Details | |
| OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | 89148 | United States | Details | |
| HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas | Nevada | 89149 | United States | Details | |
| Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | 89169 | United States | Details | |
| Nevada Cancer Research Foundation NCORP | Las Vegas | Nevada | 89169 | United States | Details | |
| Morristown Medical Center | Morristown | New Jersey | 07960 | United States | Details | |
| Overlook Hospital | Summit | New Jersey | 07902 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Vidant Oncology-Kinston | Kinston | North Carolina | 28501 | United States | Details | |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | United States | Details | |
| The Christ Hospital | Cincinnati | Ohio | 45219 | United States | Details | |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | United States | Details | |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma | 74146 | United States | Details | |
| Saint Charles Health System | Bend | Oregon | 97701 | United States | Details | |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | United States | Details | |
| Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | 97015 | United States | Details | |
| Bay Area Hospital | Coos Bay | Oregon | 97420 | United States | Details | |
| Providence Milwaukie Hospital | Milwaukie | Oregon | 97222 | United States | Details | |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | United States | Details | |
| Providence Willamette Falls Medical Center | Oregon City | Oregon | 97045 | United States | Details | |
| Providence Portland Medical Center | Portland | Oregon | 97213 | United States | Details | |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | United States | Details | |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Prisma Health Cancer Institute - Spartanburg | Boiling Springs | South Carolina | 29316 | United States | Details | |
| Prisma Health Cancer Institute - Easley | Easley | South Carolina | 29640 | United States | Details | |
| Greenville Health System Cancer Institute-Andrews | Greenville | South Carolina | 29601 | United States | Details | |
| Prisma Health Cancer Institute - Butternut | Greenville | South Carolina | 29605 | United States | Details | |
| Prisma Health Cancer Institute - Faris | Greenville | South Carolina | 29605 | United States | Details | |
| Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | 29605 | United States | Details | |
| Prisma Health Cancer Institute - Eastside | Greenville | South Carolina | 29615 | United States | Details | |
| Prisma Health Cancer Institute - Greer | Greer | South Carolina | 29650 | United States | Details | |
| Prisma Health Cancer Institute - Seneca | Seneca | South Carolina | 29672 | United States | Details | |
| Bristol Regional Medical Center | Bristol | Tennessee | 37620 | United States | Details | |
| Wellmont Medical Associates Oncology and Hematology-Johnson City | Johnson City | Tennessee | 37604 | United States | Details | |
| Ballad Health Cancer Care - Kingsport | Kingsport | Tennessee | 37660 | United States | Details | |
| Wellmont Holston Valley Hospital and Medical Center | Kingsport | Tennessee | 37660 | United States | Details | |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | United States | Details | |
| Southwest VA Regional Cancer Center | Norton | Virginia | 24273 | United States | Details | |
| Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | 98520 | United States | Details | |
| Cancer Care Center at Island Hospital | Anacortes | Washington | 98221 | United States | Details | |
| Swedish Cancer Institute-Eastside Oncology Hematology | Bellevue | Washington | 98005 | United States | Details | |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | United States | Details | |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | United States | Details | |
| Swedish Cancer Institute-Edmonds | Edmonds | Washington | 98026 | United States | Details | |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | United States | Details | |
| Swedish Cancer Institute-Issaquah | Issaquah | Washington | 98029 | United States | Details | |
| Providence Regional Cancer System-Lacey | Lacey | Washington | 98503 | United States | Details | |
| PeaceHealth Saint John Medical Center | Longview | Washington | 98632 | United States | Details | |
| Minor and James Medical PLLC | Seattle | Washington | 98104 | United States | Details | |
| Pacific Gynecology Specialists | Seattle | Washington | 98104 | United States | Details | |
| Swedish Medical Center-Ballard Campus | Seattle | Washington | 98107 | United States | Details | |
| Kaiser Permanente Washington | Seattle | Washington | 98112 | United States | Details | |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122-4307 | United States | Details | |
| Providence Regional Cancer System-Shelton | Shelton | Washington | 98584 | United States | Details | |
| MultiCare Deaconess Cancer and Blood Specialty Center - Valley | Spokane Valley | Washington | 99216 | United States | Details | |
| MultiCare Deaconess Cancer and Blood Specialty Center - Downtown | Spokane | Washington | 99204 | United States | Details | |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | United States | Details | |
| Compass Oncology Vancouver | Vancouver | Washington | 98684 | United States | Details | |
| Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | 99362 | United States | Details | |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | United States | Details | |
| Providence Regional Cancer System-Yelm | Yelm | Washington | 98597 | United States | Details | |
| Green Bay Oncology at Saint Vincent Hospital | Green Bay | Wisconsin | 54301-3526 | United States | Details | |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | United States | Details | |
| Green Bay Oncology Limited at Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | United States | Details | |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | United States | Details | |
| University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53792 | United States | Details | |
| Holy Family Memorial Hospital | Manitowoc | Wisconsin | 54221 | United States | Details | |
| Bay Area Medical Center | Marinette | Wisconsin | 54143 | United States | Details | |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | United States | Details | |
| Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | 54154 | United States | Details | |
| HSHS Saint Nicholas Hospital | Sheboygan | Wisconsin | 53081 | United States | Details | |
| Green Bay Oncology - Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235 | United States | Details | |
| Rocky Mountain Oncology | Casper | Wyoming | 82609 | United States | Details | |
| Big Horn Basin Cancer Center | Cody | Wyoming | 82414 | United States | Details | |
| Billings Clinic-Cody | Cody | Wyoming | 82414 | United States | Details | |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | United States | Details | |
| Cross Cancer Institute | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| University Health Network-Princess Margaret Hospital | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| CHUM - Hopital Notre-Dame | Montreal | Quebec | H2L 4M1 | Canada | Details | |
| Saskatoon Cancer Centre | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details |