Clinical Trial Detail


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NCT ID NCT01844674
Title A Study on the Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine in Patients With BRAFV600 Mutation-Positive Metastatic Malignancies
Recruitment Completed
Gender both
Phase Phase I
Variant Requirements Yes
Sponsors Hoffmann-La Roche

Advanced Solid Tumor



Tizanidine + Vemurafenib

Age Groups: adult | senior
Covered Countries USA | CAN

Facility Status City State Zip Country Details
Diablo Valley Oncology and Hematology Pleasant Hill California 94523 United States Details
Karmanos Cancer Center Detroit Michigan 48201 United States Details
Duke University Health Systems Durham North Carolina 27710 United States Details
Instituto Nacional do Cancer - INCA Rio de Janeiro RJ 20560-120 Brazil Details
Hospital de Caridade de Ijui; Oncologia Ijui RS 98700-000 Brazil Details
CITO - Centro Integrado de Terapia Onco-Hematológica - Hospital da Cidade de Passo Fundo Passo Fundo RS 99010-260 Brazil Details
Hospital Sao Lucas - PUCRS Porto Alegre RS 90610-000 Brazil Details
CSSS champlain - Charles-Le Moyne Greenfield Park Quebec J4V 2H1 Canada Details
Bank of Cyprus Oncology Center Nicosia 2006 Cyprus Details
Severance Hospital, Yonsei University Health System Seoul 03722 Korea, Republic of Details
Samsung Medical Center Seoul 06351 Korea, Republic of Details
Asan Medical Center. Seoul 138-736 Korea, Republic of Details
*Shaded cells indicate that there was no data available from for the field