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| NCT ID | NCT02002689 |
| Title | LDE225 for Patients With PTCH1 or SMO Mutated Tumors |
| Acronym | SIGNATURE |
| Recruitment | Terminated |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of California Davis Cancer Center UC Davis Cancer (3) | Sacramento | California | 95817 | United States | Details | |
| Rocky Mountain Cancer Centers RMCC - Aurora | Greenwood Village | Colorado | United States | Details | ||
| Lurie Children's Hospital of Chicago Developmental Therapeutics | Chicago | Illinois | 60611 | United States | Details | |
| Minnesota Oncology Hematology, P.A. Southdate Medical Center | Minneapolis | Minnesota | 55404 | United States | Details | |
| Cleveland Clinic Foundation Cleveland Clinic (19) | Cleveland | Ohio | 44195 | United States | Details | |
| Sanford Research Sanford Health | Sioux Falls | South Dakota | 57104 | United States | Details | |
| Oncology Consultants Oncology Group | Houston | Texas | 77024 | United States | Details | |
| MD Anderson Cancer Center/University of Texas MD Anderson Cancer Center (3) | Houston | Texas | 77030 | United States | Details | |
| Intermountain Medical Center Intermountain Healthcare | Murray | Utah | 84157 | United States | Details | |
| Seattle Cancer Care Alliance Skagit Valley Hospital | Seattle | Washington | 98109-1023 | United States | Details |