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| NCT ID | NCT02031458 |
| Title | A Phase 2 Study of MPDL3280A (an Engineered Anti-PDL1 Antibody) in Patients With PD-L1 Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer - BIRCH |
| Acronym | BIRCH |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | United States | Details | |
| HonorHealth Research Institute - Bisgrove | Scottsdale | Arizona | 85258 | United States | Details | |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | United States | Details | |
| Angeles Clinic & Rsch Inst | Los Angeles | California | 90025 | United States | Details | |
| City of Hope National Medical Group | South Pasadena | California | 91030 | United States | Details | |
| Stanford Cancer Center | Stanford | California | 94305-5820 | United States | Details | |
| University of Colorado Health Science Center; Biomedical Research Bldg. Room 511 | Aurora | Colorado | 80045 | United States | Details | |
| Yale Cancer Center; Medical Oncology | New Haven | Connecticut | 06520 | United States | Details | |
| Georgetown University Medical Center Lombardi Cancer Center | Washington | District of Columbia | 20007 | United States | Details | |
| Florida Cancer Specialists; SCRI | Fort Myers | Florida | 33901 | United States | Details | |
| Florida Hospital Cancer Inst | Orlando | Florida | 32804 | United States | Details | |
| Hematology Oncology Associates of the Treasure Coast | Port Saint Lucie | Florida | 34952 | United States | Details | |
| Florida Cancer Specialists. | Saint Petersburg | Florida | 33705 | United States | Details | |
| Emory Uni - Winship Cancer Center; Hematology/Oncology | Atlanta | Georgia | 30322 | United States | Details | |
| Northwest Georgia Oncology Centers PC - Marietta | Marietta | Georgia | 30060 | United States | Details | |
| Northwestern University; Robert H. Lurie Comp Can Ctr | Chicago | Illinois | 60611 | United States | Details | |
| University Of Chicago Medical Center; Section Of Hematology/Oncology | Chicago | Illinois | 60637 | United States | Details | |
| Uni of Maryland; Greenebaum Cancer Center | Baltimore | Maryland | 21201 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Beth Israel Deaconess Med Ctr; Hem/Onc | Boston | Massachusetts | 02215 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | United States | Details | |
| Monter Cancer Center | Lake Success | New York | 11042 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Carolina BioOncology Institute, PLCC | Huntersville | North Carolina | 28078 | United States | Details | |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45242 | United States | Details | |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | United States | Details | |
| Ohio State University; B406 Starling-Loving Hall | Columbus | Ohio | 43210 | United States | Details | |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | United States | Details | |
| Fox Chase Cancer Center; Hematology/Oncology | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Tennessee Oncology PLLC - Nashville (20th Ave) | Nashville | Tennessee | 37203 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Huntsman Cancer Institute; University of Utah | Salt Lake City | Utah | 84112 | United States | Details | |
| University of Virginia; Office of Sponsored Programs | Charlottesville | Virginia | 22902 | United States | Details | |
| University of Washington Seattle Cancer Care Alliance | Seattle | Washington | 98195 | United States | Details | |
| University of Wisconsin | Madison | Wisconsin | 53792 | United States | Details | |
| Royal North Shore Hospital; Oncology | St. Leonards | New South Wales | 2065 | Australia | Details | |
| Princess AleXandra Hospital; Department of Medical Oncology | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Austin Health | Heidelberg | Victoria | 3084 | Australia | Details | |
| Peter Maccallum Cancer Institute; Medical Oncology | Melbourne | Victoria | 3000 | Australia | Details | |
| Sir Charles Gairdner Hospital; Medical Oncology | Nedlands | Western Australia | 6009 | Australia | Details | |
| Cliniques Universitaires St-Luc | Bruxelles | 1200 | Belgium | Details | ||
| GHdC Site Saint-Joseph | Charleroi | 6000 | Belgium | Details | ||
| UZ Leuven Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| Sint Augustinus Wilrijk | Wilrijk | 2610 | Belgium | Details | ||
| University Clinical Centre of the Republic of Srpska | Banja Luka | 78000 | Bosnia and Herzegovina | Details | ||
| University Clinical Center Sarajevo;Clinic for Pulmonary disease | Sarajevo | 71000 | Bosnia and Herzegovina | Details | ||
| University Clinical Center Sarajevo;Institute of oncology | Sarajevo | 71000 | Bosnia and Herzegovina | Details | ||
| Complex Oncology Center (COC)-Plovidiv | Plovdiv | 4000 | Bulgaria | Details | ||
| Specialized Hospital for Active Treatment of Oncology | Sofia | 1756 | Bulgaria | Details | ||
| BCCA-Vancouver Cancer Centre | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Lakeridge Health Oshawa; Oncology | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| The Ottawa Hospital Cancer Centre; Oncology | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Odette Cancer Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| University Health Network; Princess Margaret Hospital; Medical Oncology Dept | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Hopital Augustin Morvan; Oncologie Thoracique | Brest | 29609 | France | Details | ||
| Hopital Cote De Nacre; Pneumologie | Caen | 14000 | France | Details | ||
| CHU Limoges - Dupuytren; Oncologie Thoracique Cutanee | Limoges | 87042 | France | Details | ||
| Centre Leon Berard; Departement Oncologie Medicale | Lyon | 69373 | France | Details | ||
| Hopital Arnaud De Villeneuve; Maladies Respiratoires | Montpellier | 34295 | France | Details | ||
| Centre René Gauducheau - cancer Nantes - Atlantique; Service Oncologie Médicale | Nantes | 44805 | France | Details | ||
| Nouvel Hopital Civil; Pneumologie | Strasbourg | 67091 | France | Details | ||
| Institut Gustave Roussy; Departement Oncologie Medicale | Villejuif | 94805 | France | Details | ||
| Research institute for Clinical Medicine | Tbilisi | 0112 | Georgia | Details | ||
| Cancer Research Centre | Tbilisi | 0159 | Georgia | Details | ||
| MediClab Georgia | Tbilisi | 0160 | Georgia | Details | ||
| Chemotherapy and Immunotherapy Clinic Medulla | Tbilisi | 0186 | Georgia | Details | ||
| Universitätsklinikum Essen; Innere Klinik und Poliklinik für Tumorforschung | Essen | 45122 | Germany | Details | ||
| LungenClinic Großhansdorf GmbH | Großhansdorf | 22927 | Germany | Details | ||
| Klinikum Nuernberg Nord; Medizinische Klinik 3, Schwerpunkt Pneumologie, Allergologie, Schlafmedizin | Nürnberg | 90419 | Germany | Details | ||
| Pius-Hospital; Klinik fuer Haematologie und Onkologie | Oldenburg | 26121 | Germany | Details | ||
| Schwarzwald-Baar Klinikum/VS GmbH; Onkologie/Hämatologie/Infektologie | Villingen-Schwenningen | 78052 | Germany | Details | ||
| Queen Elizabeth Hospital; Clinical Oncology | Hong Kong | Hong Kong | Details | |||
| Queen Mary Hospital; Dept. of Clinical Oncology | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hosp; Dept. Of Clinical Onc | Shatin | Hong Kong | Details | |||
| IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica | Meldola | Emilia-Romagna | 47014 | Italy | Details | |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1 | Milano | Lombardia | 20133 | Italy | Details | |
| Az. Osp. S. Luigi Gonzaga; Malattie Apparato Respiratorio 5 Ad Indirizzo Oncologico | Orbassano | Piemonte | 10043 | Italy | Details | |
| National Hospital Organization Kyushu Medical Center; Respiratory Internal Medicine | Fukuoka | 810-8563 | Japan | Details | ||
| Kanagawa Cardiovascular and Respiratory Center; Respiratory Medicine | Kanagawa | 236-0051 | Japan | Details | ||
| Yokohama Municipal Citizen'S Hospital; Respiratory Medicine | Kanagawa | 240-8555 | Japan | Details | ||
| Kitasato University Hospital; Respiratory Medicine | Kanagawa | 252-0375 | Japan | Details | ||
| Kyoto University Hospital, Respiratory Medicine | Kyoto | 606-8507 | Japan | Details | ||
| Sendai Kousei Hospital; Pulmonary Medicine | Miyagi | 980-0873 | Japan | Details | ||
| Osaka International Cancer Institute; Thoracic Oncology | Osaka | 541-8567 | Japan | Details | ||
| Kansai Medical university Hospital; Thoracic Oncology | Osaka | 573-1191 | Japan | Details | ||
| Osaka Habikino Medical Center | Osaka | 583-8588 | Japan | Details | ||
| National Cancer Center Hospital; Thoracic Medical Oncology | Tokyo | 104-0045 | Japan | Details | ||
| Toranomon Hospital; Respiratory Medicine | Tokyo | 105-8470 | Japan | Details | ||
| Antoni Van Leeuwenhoek Ziekenhuis; Thoracic Oncology | Amsterdam | 1066 CX | Netherlands | Details | ||
| Amphia Ziekenhuis; Afdeling Longziekten | Breda | 4818 CK | Netherlands | Details | ||
| Academ Ziekenhuis Groningen; Medical Oncology | Groningen | 9713 GZ | Netherlands | Details | ||
| National University Hospital; National University Cancer Institute, Singapore (NCIS) | Singapore | 119228 | Singapore | Details | ||
| National Cancer Centre; Medical Oncology | Singapore | 169610 | Singapore | Details | ||
| Institute of Oncology Ljubljana | Ljubljana | 1000 | Slovenia | Details | ||
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Barcelona | 08035 | Spain | Details | ||
| ICO Badalona - Hospital Germans Trias i Pujol | Barcelona | 08916 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Universitaetsspital Basel; Onkologie | Basel | 4031 | Switzerland | Details | ||
| CHUV; Departement d'Oncologie | Lausanne | 1011 | Switzerland | Details | ||
| Kantonsspital St. Gallen; Onkologie/Hämatologie | St. Gallen | 9007 | Switzerland | Details | ||
| UniversitätsSpital Zürich; Zentrum für Hämatologie und Onkologie, Klinik für Onkologie | Zürich | 8091 | Switzerland | Details | ||
| Hacettepe Uni Medical Faculty Hospital; Oncology Dept | Ankara | 06100 | Turkey | Details | ||
| Ankara Ataturk Chest Diseases Training and Research Hospital | Ankara | 06500 | Turkey | Details | ||
| Ege University School of Medicine; Chest Diseases Department | Izmir | 35100 | Turkey | Details | ||
| Inonu University Medical Faculty Turgut Ozal Medical Center Medical Oncology Department | Malatya | 44280 | Turkey | Details | ||
| Barts & London School of Med; Medical Oncology | London | EC1A 7BE | United Kingdom | Details | ||
| Royal Marsden Hospital - London | London | SW3 6JJ | United Kingdom | Details | ||
| Royal Marsden NHS Foundation Trust | Sutton | SM2 5PT | United Kingdom | Details |