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| NCT ID | NCT02278250 |
| Title | An Open-Label Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of M4344 (Formerly VX-803) as a Single Agent and in Combination With Cytotoxic Chemotherapy in Participants With Advanced Solid Tumors |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | Yes |
| Sponsors | EMD Serono Research & Development Institute, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | GBR | ESP |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-5901 | United States | Details | |
| Washington University in St. Louis | Saint Louis | Missouri | 63110 | United States | Details | |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 8903 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center (MSKCC) | New York | New York | 10065 | United States | Details | |
| Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | United States | Details | |
| Froedtert & The Medical College of Wisconsin | Wauwatosa | Wisconsin | 53226 | United States | Details | |
| Erasmus Medisch Centrum | Rotterdam | 3075 EA | Netherlands | Details | ||
| Hospital Clinic de Barcelona | Barcelona | Spain | Details | |||
| Hospital Universitari Vall d'Hebron | Barcelona | Spain | Details | |||
| "Fundacion Jimenez Diaz START Madrid. Oncology Phase I" | Madrid | Spain | Details | |||
| START Madrid. Fundacion Jimenez Diaz- Oncologia-Fase I | Madrid | Spain | Details | |||
| "Hospital Clinico Universitario de Valencia Servicio de Hematologia y Oncologia Medica" | Valencia | Spain | Details | |||
| Sarah Cannon Research Institute UK | London | Greater London | W1G 6AD | United Kingdom | Details | |
| Royal Marsden Hospital | Sutton | Surrey | United Kingdom | Details |