Clinical Trial Detail


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NCT ID NCT02322814
Title A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel as Initial Treatment for Participants With Triple-Negative Breast Cancer That Has Spread
Recruitment Completed
Gender both
Phase Phase II
Variant Requirements No
Sponsors Hoffmann-La Roche

triple-receptor negative breast cancer


Cobimetinib + Paclitaxel


Atezolizumab + Cobimetinib + Paclitaxel

Atezolizumab + Cobimetinib + Nab-paclitaxel

Age Groups: adult | senior
Covered Countries USA | ITA | FRA | ESP | BEL

Facility Status City State Zip Country Details
Mercy Hospital, a Campus of Plantation General Hospital Miami Florida 33133 United States Details
Cancer Specialists of North Florida Orange Park Florida 32073 United States Details
Florida Hospital Cancer Inst Orlando Florida 32804 United States Details
Florida Cancer Research Institute Plantation Florida 33324 United States Details
Cancer Treatment Centers of America Newnan Georgia 30265 United States Details
Ingalls Memorial Hospital Harvey Illinois 60426 United States Details
Montefiore Einstein Cancer Center Bronx New York 10461 United States Details
Magee Womens Hospital Pittsburgh Pennsylvania 15213 United States Details
Medical University of South Carolina Charleston South Carolina 29425 United States Details
Avera Cancer Institute Sioux Falls South Dakota 57105 United States Details
Northwest Medical Specialties Tacoma Washington 98405 United States Details
Calvary Mater Newcastle Waratah New South Wales 2298 Australia Details
Mater Adult Hospital South Brisbane Queensland 4101 Australia Details
Peter MacCallum Cancer Centre; Medical Oncology Melbourne Victoria 3000 Australia Details
St John of God Murdoch Hospital; Oncology West Murdoch Western Australia 6150 Australia Details
Clinique Edith Cavell Bruxelles 1180 Belgium Details
AZ Sint Lucas (Sint Lucas) Gent 9000 Belgium Details
Jessa Zkh (Campus Virga Jesse) Hasselt 3500 Belgium Details
AZ Groeninge Kortrijk 8500 Belgium Details
AZ Sint Augustinus Veurne Veurne 8630 Belgium Details
Fakultni nemocnice Hradec Kralove Hradec Kralove 500 05 Czechia Details
Multiscan s.r.o. Pardubice 532 03 Czechia Details
Centre Oscar Lambret Lille 59020 France Details
Centre Régional de Lutte Contre Le Cancer Val D'aurelle Paul Lamarque Montpellier 34298 France Details
Hopital Tenon Paris 75020 France Details
Centre Eugene Marquis Centre Regional de Lutte Contre Le Cancer Rennes 35000 France Details
Chaim Sheba Medical Center Ramat Gan 5265601 Israel Details
Azienda Ospedaliero Universitaria Seconda Università Degli Studi Di Napoli Napoli Campania 80131 Italy Details
A.O.U Policlinico S. Orsola Malpighi di Bologna U.O di Medicina Interna Borghi - Pad.2 Bologna Emilia-Romagna 40138 Italy Details
Centro Di Riferimento Oncologico; SOC Oncologia Medica C Aviano Friuli-Venezia Giulia 33081 Italy Details
Policlinico Universitario Agostino Gemelli Roma Lazio 00168 Italy Details
Istituto Europeo Di Oncologia Milano Lombardia 20141 Italy Details
Azienda Ospedaliero - Universitaria Pisana U.O. Oncologia Medica 2 Universitaria - Polo Oncologico Pisa Toscana 56126 Italy Details
National Cancer Center; Medical Oncology Gyeonggi-do 410-769 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
Korea University Guro Hospital Seoul 08308 Korea, Republic of Details
Yonsei University Health System/Severance Hospital Seoul 120-752 Korea, Republic of Details
Riga East Clinical University Hospital Latvian Oncology Centre Riga LV-1079 Latvia Details
Pauls Stradins Clinical University Hospital Rīga LV-1002 Latvia Details
Prof. Dr. I. Chiricuta Institute of Oncology Cluj Napoca 400015 Romania Details
Oncology Center Sf. Nectarie Craiova 200347 Romania Details
Corporacio Sanitaria Parc Tauli; Servicio de Oncologia Sabadell Barcelona 8208 Spain Details
Organización Sanitaria Integrada Bilbao Basurto Bilbao Vizcaya 48013 Spain Details
Hospital Universitario Infanta Cristina; Servicio de Oncologia Badajoz 06080 Spain Details
Hospital Universitario Ramon y Cajal Madrid 28034 Spain Details
Fundacion Jimenez Diaz; Servicio de Oncologia Madrid 28040 Spain Details
Hospital Clinico San Carlos; Servicio de Nefrologia Madrid 28040 Spain Details
Hosp. Regional Univ. de Malaga - Hospital Materno Infantil; Hospital Materno Infantil de Malaga Malaga 29011 Spain Details
Chang Gung Memorial Hospital Kaohsiung Country 833 Taiwan Details
Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology Taipei City 11259 Taiwan Details
Nuffield Health Bournemouth Hospital Bournemouth BH1 1RW United Kingdom Details
Mount Vernon Hospital Middlesex HA6 2RN United Kingdom Details
Nottingham University Hospitals City Campus Nottingham NG5 1PB United Kingdom Details
*Shaded cells indicate that there was no data available from for the field