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NCT ID NCT02335918
Title A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors
Recruitment Completed
Gender both
Phase Phase Ib/II
Variant Requirements No
Sponsors Celldex Therapeutics
Indications

colorectal cancer

ovarian cancer

lung non-small cell carcinoma

melanoma

head and neck squamous cell carcinoma

Therapies

Nivolumab + Varlilumab

Age Groups: adult
Covered Countries USA

Facility Status City State Zip Country Details
University of Arizona Cancer Center Tucson Arizona 85719 United States Details
The Stanford Center for Clinical and Translational Education and Research Palo Alto California 94304 United States Details
UCSF Helen Diller Family Comprehensive Cancer Center San Francisco California 94115 United States Details
University of Colorado Medical Center Aurora Colorado 80045 United States Details
Smilow Cancer Hospital at Yale University Cancer Center New Haven Connecticut 06519 United States Details
Georgetown University Washington District of Columbia 20007 United States Details
George Washington University School of Medicine and Health Sciences Washington District of Columbia 20037 United States Details
Mount Sinai Medical Center Miami Beach Florida 33140 United States Details
Northwest Georgia Oncology Centers PC Marietta Georgia 30060 United States Details
Parkview Research Center Fort Wayne Indiana 46845 United States Details
Dana Farber Cancer Institute Boston Massachusetts 02115 United States Details
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 United States Details
Laura and Isaac Perlmutter Cancer Center New York New York 10016 United States Details
Columbia University Medical Center New York New York 10032 United States Details
Memorial Sloan Kettering Cancer Center New York New York 10065 United States Details
Wake Forest Baptist Health Winston-Salem North Carolina 27157 United States Details
Cleveland Clinic Cleveland Ohio 44195 United States Details
Providence Health & Services Portland Oregon 97213 United States Details
Inova Schar Cancer Institute Research Fairfax Virginia 22031 United States Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field