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| NCT ID | NCT02737501 |
| Title | ALTA-1L Study: A Phase 3 Study of Brigatinib Versus Crizotinib in Anaplastic Lymphoma Kinase (ALK)-Positive Advanced Non-small Cell Lung Cancer (NSCLC) Participants (ALTA-1L) |
| Acronym | ALTA-1L |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Ariad Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| USOR - Arizona Oncology Associates - Sedona | Sedona | Arizona | 86336 | United States | Details | |
| Kaiser Permanente Bellflower Medical Offices | Bellflower | California | 90706 | United States | Details | |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | United States | Details | |
| Rocky Mountain Cancer Centers - Boulder | Boulder | Colorado | 80303-1385 | United States | Details | |
| Sylvester Comprehensive Cancer Center | Deerfield Beach | Florida | 33442 | United States | Details | |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States | Details | |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | United States | Details | |
| Minnesota Oncology | Coon Rapids | Minnesota | 55433 | United States | Details | |
| Montefiore Medical Center | Bronx | New York | 10461 | United States | Details | |
| Oncology Hematology Care - Blue Ash | Cincinnati | Ohio | 45242-5665 | United States | Details | |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Virginia Cancer Specialists - Fairfax Office | Fairfax | Virginia | 22031 | United States | Details | |
| Saint George Hospital | Kogarah | New South Wales | 2217 | Australia | Details | |
| Royal North Shore Hospital | St Leonards | New South Wales | 2065 | Australia | Details | |
| Monash Medical Centre | Bentleigh East | Victoria | 3165 | Australia | Details | |
| Saint Vincent's Hospital Melbourne | Fitzroy | Victoria | 3065 | Australia | Details | |
| Universitatsklinium St. Polten | Sankt Polten | Lower Austria | 3100 | Austria | Details | |
| Otto-Wagner-Spital Baumgartner Hohe | Vienna | 1140 | Austria | Details | ||
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Odense University Hospital | Odense C | 5000 | Denmark | Details | ||
| Centre de Lutte Contre le Cancer Francois Baclesse | CAEN Cedex 5 | Basse-normandie | 14076 | France | Details | |
| Hopital Charles Nicolle | Rouen | Haute-normandie | 76041 | France | Details | |
| Centre Hospitalier Intercommunal de Creteil | Creteil | Ile-de-france | 94010 | France | Details | |
| Hopital Tenon | Paris | Ile-de-france | 75020 | France | Details | |
| Centre Hospitalier Universitaire Hopital Nord | Marseille Cedex 20 | Provence Alpes COTE D'azur | 13915 | France | Details | |
| Hopital Albert Michallon | Grenoble Cedex 9 | Rhone-alpes | 38043 | France | Details | |
| Centre Leon Berard | Lyon | Rhone-alpes | 69008 | France | Details | |
| Universitatsklinik Freiburg | Freiburg | Baden-wuerttemberg | 79106 | Germany | Details | |
| Thoraxklinik Heidelberg gGmbH | Heidelberg | Baden-wuerttemberg | 69126 | Germany | Details | |
| Pius Hospital Oldenburg | Oldenburg | Niedersachsen | 26121 | Germany | Details | |
| Kliniken der Stadt Koeln gGmbH - Krankenhaus Merheim | Koln | Nordrhein-westfalen | 51109 | Germany | Details | |
| Evangelische Lungenklinik Berlin | Berlin | 13125 | Germany | Details | ||
| Studiengesellschaft Haemato-Onkologie Hamburg Prof. Laack und Partner | Hamburg | 20251 | Germany | Details | ||
| Tuen Mun Hospital | Tuen Mun | New Territories | Hong Kong | Details | ||
| Queen Mary Hospital | Hong Kong | Hong Kong | Details | |||
| Queen Elizabeth Hospital | Kowloon | 150001 | Hong Kong | Details | ||
| Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori | Meldola | Forli-cesena | 47014 | Italy | Details | |
| Azienda Ospedaliera San Gerardo di Monza | Monza | Monza E Brianza | 20052 | Italy | Details | |
| Centro di Riferimento Oncologico di Aviano | Aviano | Pordenone | 33081 | Italy | Details | |
| Azienda Ospedaliera San Giuseppe Moscati | Avellino | 83100 | Italy | Details | ||
| Istituto Oncologico di Bari Giovanni Paolo II | Bari | 70124 | Italy | Details | ||
| Azienda Ospedaliero Universitaria di Bologna Policlinico Sant'Orsola-Malpighi | Bologna | 40138 | Italy | Details | ||
| Istituto Scientifico Universitario San Raffaele | Milano | 20132 | Italy | Details | ||
| Istituto Europeo di Oncologia | Milano | 20141 | Italy | Details | ||
| Istituto Tumori Napoli Fondazione G. Pascale | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Maggiore della Carita | Novara | 28100 | Italy | Details | ||
| Azienda Ospedaliera di Perugia - Ospedale S. Maria della Misericordia | Perugia | 06132 | Italy | Details | ||
| Azienda Unita Sanitaria Locale di Ravenna | Ravenna | 48121 | Italy | Details | ||
| Policlinico Universitario Campus Bio-Medico | Roma | 00128 | Italy | Details | ||
| Chungbuk National University Hospital | Cheongju | Chungcheongbuk-do | 28644 | Korea, Republic of | Details | |
| National Cancer Center | Goyang-si | Gyeonggi-do | 10408 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 13620 | Korea, Republic of | Details | |
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea | Seoul | 06591 | Korea, Republic of | Details | ||
| Centre Hospitalier de Luxembourg - Hopital Municipal | Luxembourg | 1210 | Luxembourg | Details | ||
| Amphia Ziekenhuis - Locatie Langendijk Breda | Breda | Noord-brabant | 4818 CK | Netherlands | Details | |
| Antoni van Leeuwenhoekziekenhuis | Amsterdam | Noord-holland | 1066 CX | Netherlands | Details | |
| Isala Klinieken | Zwolle | Overijssel | 8025 AB | Netherlands | Details | |
| Universitair Medisch Centrum Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| Radiumhospitalet | Oslo | 0379 | Norway | Details | ||
| National University Hospital | Singapore | 119228 | Singapore | Details | ||
| National Cancer Centre Singapore | Singapore | 169610 | Singapore | Details | ||
| OncoCare Cancer Centre | Singapore | 258499 | Singapore | Details | ||
| Hospital Universitario Central de Asturias | Oviedo | Asturias | 33011 | Spain | Details | |
| Hospital Universitari Germans Trias i Pujol | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Universitario Puerta de Hierro - Majadahonda | Majadahonda | Madrid | 28222 | Spain | Details | |
| Hospital General Universitario de Alicante | Alicante | 03010 | Spain | Details | ||
| Hospital Universitario Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Teresa Herrera - Materno Infantil | La Coruna | 15006 | Spain | Details | ||
| Hospital Ramon Y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| Hospital Regional Universitario Carlos Haya Malaga Instituto de Neurociencias Clinicas | Malaga | 29010 | Spain | Details | ||
| Hospital Universitario Marques de Valdecilla | Santander | 39008 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Karolinska Universitetssjukhuset | Stockholm | 171 76 | Sweden | Details | ||
| University Hospital Zurich | Zurich | 8091 | Switzerland | Details | ||
| National Cheng Kung University | Tainan | Taipei | 70403 | Taiwan | Details | |
| China Medical University Hospital | Taichung | 404 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Leicester Royal Infirmary | Leicester | England | LE1 5WW | United Kingdom | Details | |
| University College London | London | England | NW1 2PG | United Kingdom | Details | |
| Guy's and Saint Thomas' NHS Foundation Trust | London | England | SE1 9RT | United Kingdom | Details | |
| Royal Marsden NHS Trust | London | England | SW3 6JJ | United Kingdom | Details | |
| Maidstone Hospital | Maidstone | England | ME16 9QQ | United Kingdom | Details | |
| The Christie NHS Foundation Trust | Manchester | England | M20 4BX | United Kingdom | Details |