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NCT ID NCT02908672
Title A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Hoffmann-La Roche
Indications

melanoma

Therapies

Cobimetinib + Vemurafenib

Atezolizumab + Cobimetinib + Vemurafenib

Age Groups: adult | senior
Covered Countries USA | ITA | FRA | ESP | DEU | CAN | BEL | AUT

Facility Status City State Zip Country Details
University of Alabama at Birmingham Birmingham Alabama 35233 United States Details
Arizona Oncology Associates, PC - HAL Tempe Arizona 85284 United States Details
Highlands Oncology Group Springdale Arkansas 72762 United States Details
UC Irvine Medical Center Orange California 92868 United States Details
Mount Sinai Medical Center Miami Beach Florida 33140 United States Details
UF Health Cancer Center at Orlando Health Orlando Florida 32824 United States Details
Oncology Specialists, S.C. Park Ridge Illinois 60068 United States Details
St. Luke's University Health network Bethlehem Pennsylvania 18015 United States Details
Princess Alexandra Hospital Woolloongabba Queensland 4102 Australia Details
Royal Adelaide Hospital Adelaide South Australia 5000 Australia Details
Peter Maccallum Cancer Centre Melbourne Victoria 3000 Australia Details
Fiona Stanley Hospital Murdoch Western Australia 6150 Australia Details
Medical University of Graz, Department of Dermatology Graz 8030 Austria Details
LKH Innsbruck; Universitätsklinik für Dermatologie Innsbruck 6020 Austria Details
Medizinische Universität Wien; Univ.Klinik für Dermatologie Wien 1090 Austria Details
Cliniques Universitaires St-Luc Bruxelles 1200 Belgium Details
UZ Leuven Gasthuisberg Leuven 3000 Belgium Details
CHU Sart-Tilman Liège 4000 Belgium Details
Sint Augustinus Wilrijk Wilrijk 2610 Belgium Details
Clinicas Oncologicas Integradas - COI Rio De Janeiro RJ 22290-160 Brazil Details
Hospital das Clinicas - UFRGS Porto Alegre RS 90035-903 Brazil Details
Centro de Pesquisas Oncologicas - CEPON Florianopolis SC 88034-000 Brazil Details
Instituto do Cancer do Estado de Sao Paulo - ICESP Sao Paulo SP 01246-000 Brazil Details
Hospital Sao Jose Sao Paulo SP 01321-001 Brazil Details
Tom Baker Cancer Centre-Calgary Calgary Alberta T2N 4N2 Canada Details
Juravinski Cancer Clinic; Department of Oncology Hamilton Ontario L8V 5C2 Canada Details
LHSC - Victoria Hospital; London Regional Cancer Program London Ontario N6A 4L6 Canada Details
Lakeridge Health Oshawa; Oncology Oshawa Ontario L1G 2B9 Canada Details
The Ottawa Hospital Cancer Centre; Oncology Ottawa Ontario K1H 8L6 Canada Details
Princess Margaret Hospital Toronto Ontario M4X 1K9 Canada Details
Centre Hospitalier Affilie Universitaire de Quebec - Hopital de L'Enfant Jesus Quebec City Quebec G1J 1Z4 Canada Details
Groupe Hospitalier Saint André - Hôpital Saint André Bordeaux 33075 France Details
Hopital du Bocage; Dermatologie Dijon 21079 France Details
Centre Hospitalier Universitaire de Grenoble - Albert Michallon La Tronche 38700 France Details
Hopital Claude Huriez - CHU Lille Lille 59037 France Details
Hopital Saint Eloi; CHU de Montpellier; Svc de Dermatologie Montpellier 34295 France Details
CHU de Nantes; Cancéro-dermatologie Nantes 44093 France Details
Hopital Robert Debre; DERMATOLOGIE Reims 51092 France Details
Centre Eugene Marquis; Service d'oncologie Rennes 35042 France Details
CHU de Rouen - Hôpital Charles Nicolle Rouen 76031 France Details
Institut Gustave Roussy; Dermatologie Villejuif 94805 France Details
Charite - Universitätsmedizin Berlin Berlin 12203 Germany Details
Elbekliniken Buxtehude; Klinik für Dermatologie Buxtehude 21614 Germany Details
HELIOS Klinikum Erfurt; Klinik für Dermatologie & Allergologie Erfurt 99089 Germany Details
Universitätsklinikum Erlangen; Hautklinik Erlangen 91054 Germany Details
Universitatsklinikum Essen; Klinik für Dermatologie Essen 45147 Germany Details
Universitätsmedizin Göttingen Göttingen 37075 Germany Details
Medizinische Hochschule Hannover; Klinik für Dermatologie, Allergologie und Venerologie Hannover 30625 Germany Details
Universitatsklinik Heidelberg; Universitätshautklinik und Nationales Centrum für Tumorerkrankungen Heidelberg 69120 Germany Details
UKSH Kiel; Klinik für Dermatologie, Venerologie und Allergologie Kiel 24105 Germany Details
Klinikum d.Universität zu Köln Klinik u.Poliklinik f.Dermatologie Köln 50937 Germany Details
Universitätsklinikum Leipzig; Klinik für Dermatologie, Venerologie und Allergologie Leipzig 04103 Germany Details
UKSH Universitatsklinikum Schleswig-Holstein; Studienzentrum Dermatologie 10d Lübeck 23538 Germany Details
Universitatsklinikum Mainz; Klinik und Poliklinik fur Dermatologie Mainz 55131 Germany Details
Klinikum der Ludwigs-Maximilians-Universität München; Dermatologie München 80337 Germany Details
Fachklinik Hornheide; Dermatologie Münster 48157 Germany Details
Harzklinikum Dorothea Christiane Erxleben GmbH, Standort Quedlinburg; Hautkrebszentrum Harz Quedlinburg 06484 Germany Details
Universitätsklinikum Regensburg; Klinik und Poliklinik für Dermatologie Regensburg 93053 Germany Details
Zentrum für Dermatoonkologie, Universitäts-Hautklinik Tübingen Tübingen 72076 Germany Details
Universitätsklinikum Würzburg; Med. Klinik 1, Pneumologie Würzburg 97080 Germany Details
Laiko General Hospital Athen Athens 115 27 Greece Details
Metropolitan Hospital; Dept. of Oncology Pireaus 185 47 Greece Details
Orszagos Onkologiai Intezet; Borgyogyaszati Osztaly Budapest 1122 Hungary Details
University of Szeged Szent-Györgyi Albert Clinical Center; Department of Dermatology and Allergology Szeged 6720 Hungary Details
Rambam Health Care Campus; Oncology Haifa 3109601 Israel Details
Sharett Institute - Hadassah Hebrew University Medical Center Jerusalem 9112001 Israel Details
Rabin MC; Davidof Center - Oncology Institute Petach Tikva 4941492 Israel Details
Ella Institute - Sheba Medical Center Ramat-Gan 5265601 Israel Details
IRCCS Istituto Nazionale Tumori Fondazione Pascale; Oncologia Medica B Napoli Campania 80131 Italy Details
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica Meldola Emilia-Romagna 47014 Italy Details
A.O. Universitaria S. Maria Della Misericordia Di Udine; Oncologia Udine Friuli-Venezia Giulia 33100 Italy Details
IFO - Istituto Regina Elena; Oncologia Medica Roma Lazio 00144 Italy Details
IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST); Oncologia Medica A Genova Liguria 16132 Italy Details
Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 2 Milano Lombardia 20133 Italy Details
Irccs Istituto Europeo Di Oncologia (IEO); Oncologia Medica Milano Lombardia 20141 Italy Details
Fondazione Del Piemonte Per L'oncologia Ircc Di Candiolo; Dipartimento Oncologico Candiolo Piemonte 10060 Italy Details
Istituto Tumori "Giovanni Paolo II", Oncologia Bari Puglia 70124 Italy Details
A.O.U. Senese Policlinico Santa Maria Alle Scotte Siena Toscana 53100 Italy Details
Seoul National University Hospital Seoul 03080 Korea, Republic of Details
Severance Hospital, Yonsei University Health System Seoul 03722 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
Samsung Medical Center Seoul 06351 Korea, Republic of Details
Erasmus Mc - Daniel Den Hoed Kliniek; Interne Oncologie Rotterdam 3015AA Netherlands Details
Auckland city hospital; Auckland Regional Cancer Centre and Blood Service Auckland 1023 New Zealand Details
Wellington Hospital; Wellington Blood and Cancer Centre Newtown 6021 New Zealand Details
Mid Central DHB Palmerston North 4442 New Zealand Details
Tauranga Hospital, Clinical Trials Unit; BOP Clinical School Tauranga 3112 New Zealand Details
Uniwersyteckie Centrum Kliniczne; Klinika Onkologii i Radioterapii Gdańsk 80-214 Poland Details
Narodowy Inst.Onkol.im.Skłodowskiej-Curie Państw.Inst.Badawczy Kraków; Klinika Onkologii Klinicznej Kraków 31-115 Poland Details
COZL Oddzial Onkologii Klinicznej z pododdzialem Chemioterapii Dziennej Lublin 20-090 Poland Details
Szpital Kliniczny im. Heliodora Święcickiego UM w Poznaniu. Poznań 60-780 Poland Details
Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy Warszawa 02-781 Poland Details
Dolnośląskie Centrum Onkologii, Pulmonologii i Hematologii Wrocław 53-413 Poland Details
IPO de Lisboa; Servico de Oncologia Medica Lisboa 1099-023 Portugal Details
IPO do Porto; Servico de Oncologia Medica Porto 4200-072 Portugal Details
Moscow City Oncology Hospital #62 Moscovskaya Oblast Moskovskaja Oblast 143423 Russian Federation Details
FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin" Moscow 115478 Russian Federation Details
FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov" Saint-Petersburg Russian Federation Details
St. Petersburg Oncology Hospital St Petersburg 198255 Russian Federation Details
Clinica Universitaria de Navarra; Servicio de Oncologia Pamplona Navarra 31008 Spain Details
Hospital Universitari Vall d'Hebron; Oncology Barcelona 08035 Spain Details
Hospital Clínic i Provincial; Servicio de Oncología Barcelona 08036 Spain Details
Hospital Ramon y Cajal; Servicio de Oncologia Madrid 28034 Spain Details
Hospital Universitario La Paz; Servicio de Oncologia Madrid 28046 Spain Details
Hospital Universitario Virgen de la Macarena; Sevilla 41071 Spain Details
Fundacion Instituto Valenciano de Oncologia (IVO) Valencia 46009 Spain Details
Hospital General Universitario de Valencia; Servicio de oncologia Valencia 46014 Spain Details
Hospital Universitario Miguel Servet; Servicio Oncologia Zaragoza 50009 Spain Details
Bristol Haematology and Oncology Centre Bristol BS2 8ED United Kingdom Details
Beatson West of Scotland Cancer Centre Glasgow G12 0YN United Kingdom Details
Ipswich Hospital; Oncology Pharmacy Ipswich IP4 5PD United Kingdom Details
St James Uni Hospital; Icrf Cancer Medicine Research Unit Leeds LS9 7TF United Kingdom Details
Guys and St Thomas NHS Foundation Trust, Guys Hospital London SE1 9RT United Kingdom Details
Freeman Hospital; Northern Centre For Cancer Care New Castle Upon Tyne NE7 7DN United Kingdom Details
Singleton Hospital; Pharmacy Department Swansea SA2 8QA United Kingdom Details
Royal Cornwall Hospital Truro TR1 3LQ United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field