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| NCT ID | NCT02967692 |
| Title | A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma (COMBI-i) |
| Acronym | COMBI-i |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| California Cancer Associates for Research and Excellence SC-2 | Encinitas | California | 92024 | United States | Details | |
| UC Irvine Medical Center SC | Orange | California | 92868 | United States | Details | |
| California Pacific Medical Center | San Francisco | California | 94115 | United States | Details | |
| Stanford Cancer Center SC-2 | Stanford | California | 94305 | United States | Details | |
| University of Kansas Cancer Center SC | Westwood | Kansas | 66205 | United States | Details | |
| Johns Hopkins U SC | Lutherville | Maryland | 21093 | United States | Details | |
| Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | United States | Details | |
| NYU Laura and Isaac Perlmutter Cancer Center SC | New York | New York | 10016 | United States | Details | |
| University of Pittsburgh Med Center SC | Pittsburgh | Pennsylvania | 15213 | United States | Details | |
| University of Tennessee Medical Center SC | Knoxville | Tennessee | 37920 | United States | Details | |
| Univ of TX MD Anderson Cancer Cntr SC 2 | Houston | Texas | 77030 | United States | Details | |
| Utah Cancer Specialists SC 2 | Salt Lake City | Utah | 84106 | United States | Details | |
| Novartis Investigative Site | Caba | Buenos Aires | C1125ABD | Argentina | Details | |
| Novartis Investigative Site | Caba | Buenos Aires | C1426ANZ | Argentina | Details | |
| Novartis Investigative Site | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Novartis Investigative Site | Buenos Aires | C1431FWO | Argentina | Details | ||
| Novartis Investigative Site | Gateshead | New South Wales | 2290 | Australia | Details | |
| Novartis Investigative Site | North Sydney | New South Wales | 2060 | Australia | Details | |
| Novartis Investigative Site | Greenslopes | Queensland | 4120 | Australia | Details | |
| Novartis Investigative Site | Prahran | Victoria | 3181 | Australia | Details | |
| Novartis Investigative Site | Nedlands | Western Australia | 6009 | Australia | Details | |
| Novartis Investigative Site | Innsbruck | Tyrol | 6020 | Austria | Details | |
| Novartis Investigative Site | Graz | 8036 | Austria | Details | ||
| Novartis Investigative Site | Linz | 4020 | Austria | Details | ||
| Novartis Investigative Site | Salzburg | A-5020 | Austria | Details | ||
| Novartis Investigative Site | St Poelten | 3100 | Austria | Details | ||
| Novartis Investigative Site | Jette | Brussel | 1090 | Belgium | Details | |
| Novartis Investigative Site | Bruxelles | 1200 | Belgium | Details | ||
| Novartis Investigative Site | Curitiba | PR | 80530 010 | Brazil | Details | |
| Novartis Investigative Site | Porto Alegre | RS | 90035-003 | Brazil | Details | |
| Novartis Investigative Site | Sao Paulo | SP | 01246 000 | Brazil | Details | |
| Novartis Investigative Site | Rio de Janeiro | 20560-120 | Brazil | Details | ||
| Novartis Investigative Site | Plovdiv | 4004 | Bulgaria | Details | ||
| Novartis Investigative Site | Sofia | 1303 | Bulgaria | Details | ||
| Novartis Investigative Site | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Novartis Investigative Site | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Novartis Investigative Site | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Novartis Investigative Site | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Novartis Investigative Site | Sherbrooke | Quebec | J1H 5N4 | Canada | Details | |
| Novartis Investigative Site | Temuco | Araucania | 4810469 | Chile | Details | |
| Novartis Investigative Site | Santiago | 7500921 | Chile | Details | ||
| Novartis Investigative Site | Santiago | 8420383 | Chile | Details | ||
| Novartis Investigative Site | Zlin | Czech Republic | 762 75 | Czechia | Details | |
| Novartis Investigative Site | Hradec Kralove | CZE | 500 05 | Czechia | Details | |
| Novartis Investigative Site | Olomouc | CZE | 779 00 | Czechia | Details | |
| Novartis Investigative Site | Ostrava | Poruba | 708 52 | Czechia | Details | |
| Novartis Investigative Site | Brno | 65653 | Czechia | Details | ||
| Novartis Investigative Site | Praha 10 | 100 34 | Czechia | Details | ||
| Novartis Investigative Site | Praha | 12808 | Czechia | Details | ||
| Novartis Investigative Site | Aarhus | 8000 C | Denmark | Details | ||
| Novartis Investigative Site | Le Mans | Cedex 09 | 72037 | France | Details | |
| Novartis Investigative Site | Limoges | Haute Vienne | 87000 | France | Details | |
| Novartis Investigative Site | Amiens | 80054 | France | Details | ||
| Novartis Investigative Site | Besancon Cedex | 25030 | France | Details | ||
| Novartis Investigative Site | Bobigny Cedex | 93009 | France | Details | ||
| Novartis Investigative Site | Bordeaux Cedex | 33075 | France | Details | ||
| Novartis Investigative Site | Boulogne Billancourt | 92104 | France | Details | ||
| Novartis Investigative Site | Caen | 14033 | France | Details | ||
| Novartis Investigative Site | Clermont Ferrand | 63003 | France | Details | ||
| Novartis Investigative Site | Dijon | 21000 | France | Details | ||
| Novartis Investigative Site | Grenoble | 38043 | France | Details | ||
| Novartis Investigative Site | Lille | 59037 | France | Details | ||
| Novartis Investigative Site | Lorient | 56322 | France | Details | ||
| Novartis Investigative Site | Lyon | 69373 | France | Details | ||
| Novartis Investigative Site | Marseille Cedex 05 | 13885 | France | Details | ||
| Novartis Investigative Site | Mulhouse cedex | 68070 | France | Details | ||
| Novartis Investigative Site | Nice | 06202 | France | Details | ||
| Novartis Investigative Site | Paris 10 | 75475 | France | Details | ||
| Novartis Investigative Site | Pierre Benite | 69495 | France | Details | ||
| Novartis Investigative Site | Poitiers | 86021 | France | Details | ||
| Novartis Investigative Site | Reims | 51092 | France | Details | ||
| Novartis Investigative Site | Rouen Cedex | 76031 | France | Details | ||
| Novartis Investigative Site | Strasbourg Cedex | 67091 | France | Details | ||
| Novartis Investigative Site | Toulouse | 31059 | France | Details | ||
| Novartis Investigative Site | Vandoeuvre-les-Nancy | 54519 | France | Details | ||
| Novartis Investigative Site | Villejuif | 94800 | France | Details | ||
| Novartis Investigative Site | Mannheim | Baden Wuerttemberg | 68305 | Germany | Details | |
| Novartis Investigative Site | Regensburg | Bavaria | 93053 | Germany | Details | |
| Novartis Investigative Site | Berlin | 13353 | Germany | Details | ||
| Novartis Investigative Site | Berlin | 13578 | Germany | Details | ||
| Novartis Investigative Site | Bonn | 53105 | Germany | Details | ||
| Novartis Investigative Site | Chemnitz | 09117 | Germany | Details | ||
| Novartis Investigative Site | Dresden | 01307 | Germany | Details | ||
| Novartis Investigative Site | Duesseldorf | 40225 | Germany | Details | ||
| Novartis Investigative Site | Erfurt | 99089 | Germany | Details | ||
| Novartis Investigative Site | Essen | 45147 | Germany | Details | ||
| Novartis Investigative Site | Freiburg | 79106 | Germany | Details | ||
| Novartis Investigative Site | Gera | 07548 | Germany | Details | ||
| Novartis Investigative Site | Halle Saale | 06120 | Germany | Details | ||
| Novartis Investigative Site | Hamburg | 20246 | Germany | Details | ||
| Novartis Investigative Site | Hannover | 30625 | Germany | Details | ||
| Novartis Investigative Site | Heidelberg | 69120 | Germany | Details | ||
| Novartis Investigative Site | Homburg | 66421 | Germany | Details | ||
| Novartis Investigative Site | Kiel | 24105 | Germany | Details | ||
| Novartis Investigative Site | Leipzig | 04103 | Germany | Details | ||
| Novartis Investigative Site | Mainz | 55131 | Germany | Details | ||
| Novartis Investigative Site | Marburg | 35039 | Germany | Details | ||
| Novartis Investigative Site | Minden | 32429 | Germany | Details | ||
| Novartis Investigative Site | Muenchen | 81377 | Germany | Details | ||
| Novartis Investigative Site | Muenster | 48157 | Germany | Details | ||
| Novartis Investigative Site | Stade | 21682 | Germany | Details | ||
| Novartis Investigative Site | Tuebingen | 72076 | Germany | Details | ||
| Novartis Investigative Site | Athens | 115 27 | Greece | Details | ||
| Novartis Investigative Site | Athens | 18547 | Greece | Details | ||
| Novartis Investigative Site | Budapest | H 1122 | Hungary | Details | ||
| Novartis Investigative Site | Debrecen | 4032 | Hungary | Details | ||
| Novartis Investigative Site | Szeged | H 6725 | Hungary | Details | ||
| Novartis Investigative Site | Haifa | 3109601 | Israel | Details | ||
| Novartis Investigative Site | Jerusalem | 9112001 | Israel | Details | ||
| Novartis Investigative Site | Ramat Gan | 52621 | Israel | Details | ||
| Novartis Investigative Site | Bari | BA | 70124 | Italy | Details | |
| Novartis Investigative Site | Bergamo | BG | 24127 | Italy | Details | |
| Novartis Investigative Site | Bologna | BO | 40138 | Italy | Details | |
| Novartis Investigative Site | Brescia | BS | 25123 | Italy | Details | |
| Novartis Investigative Site | Meldola | FC | 47014 | Italy | Details | |
| Novartis Investigative Site | Genova | GE | 16132 | Italy | Details | |
| Novartis Investigative Site | Monza | MB | 20900 | Italy | Details | |
| Novartis Investigative Site | Milano | MI | 20133 | Italy | Details | |
| Novartis Investigative Site | Milano | MI | 20141 | Italy | Details | |
| Novartis Investigative Site | Modena | MO | 41124 | Italy | Details | |
| Novartis Investigative Site | Padova | PD | 35100 | Italy | Details | |
| Novartis Investigative Site | Roma | RM | 00167 | Italy | Details | |
| Novartis Investigative Site | Siena | SI | 53100 | Italy | Details | |
| Novartis Investigative Site | Candiolo | TO | 10060 | Italy | Details | |
| Novartis Investigative Site | Torino | TO | 10126 | Italy | Details | |
| Novartis Investigative Site | Verona | VR | 37126 | Italy | Details | |
| Novartis Investigative Site | Napoli | 80131 | Italy | Details | ||
| Kyushu University Hospital | Fukuoka city | Fukuoka | 812-8582 | Japan | Details | |
| Kyoto University Hospital | Sakyo Ku | Kyoto | 606 8507 | Japan | Details | |
| Osaka International Cancer Institute | Osaka-city | Osaka | 541-8567 | Japan | Details | |
| Tokyo Metropolitan Komagome Hospital | Bunkyo ku | Tokyo | 113-8677 | Japan | Details | |
| National Cancer Hospital | Chuo ku | Tokyo | 104 0045 | Japan | Details | |
| Novartis Investigative Site | Mexico | Distrito Federal | 14080 | Mexico | Details | |
| Novartis Investigative Site | Leon | Guanajuato | 37178 | Mexico | Details | |
| Novartis Investigative Site | Guadalajara | Jalisco | 44100 | Mexico | Details | |
| Novartis Investigative Site | Breda | 4819 EV | Netherlands | Details | ||
| Novartis Investigative Site | Leiden | 2300 RC | Netherlands | Details | ||
| Novartis Investigative Site | Oslo | 0379 | Norway | Details | ||
| Novartis Investigative Site | Gdansk | 80 952 | Poland | Details | ||
| Novartis Investigative Site | Warszawa | 02 781 | Poland | Details | ||
| Novartis Investigative Site | Lisboa | 1099 023 | Portugal | Details | ||
| Novartis Investigative Site | Porto | 4200-072 | Portugal | Details | ||
| Novartis Investigative Site | Chelyabinsk | 454048 | Russian Federation | Details | ||
| Novartis Investigative Site | Moscow | 115478 | Russian Federation | Details | ||
| Novartis Investigative Site | Moscow | 143423 | Russian Federation | Details | ||
| Novartis Investigative Site | Nizhny Novgorod | 603137 | Russian Federation | Details | ||
| Novartis Investigative Site | Omsk | 644013 | Russian Federation | Details | ||
| Novartis Investigative Site | Saint Petersburg | 198255 | Russian Federation | Details | ||
| Novartis Investigative Site | Samara | 443011 | Russian Federation | Details | ||
| Novartis Investigative Site | St Petersburg | 197758 | Russian Federation | Details | ||
| Novartis Investigative Site | Malaga | Andalucia | 29010 | Spain | Details | |
| Novartis Investigative Site | Sevilla | Andalucia | 41009 | Spain | Details | |
| Novartis Investigative Site | Oviedo | Asturias | 33011 | Spain | Details | |
| Novartis Investigative Site | Jerez | Cadiz | 11407 | Spain | Details | |
| Novartis Investigative Site | Badalona | Catalunya | 08916 | Spain | Details | |
| Novartis Investigative Site | Barcelona | Catalunya | 08036 | Spain | Details | |
| Novartis Investigative Site | Valencia | Comunidad Valenciana | 46014 | Spain | Details | |
| Novartis Investigative Site | La Coruna | Galicia | 15006 | Spain | Details | |
| Novartis Investigative Site | Las Palmas De Gran Canarias | 35016 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28009 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28034 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28050 | Spain | Details | ||
| Novartis Investigative Site | Madrid | 28222 | Spain | Details | ||
| Novartis Investigative Site | Goteborg | SE-413 45 | Sweden | Details | ||
| Novartis Investigative Site | Lund | 221 85 | Sweden | Details | ||
| Novartis Investigative Site | Stockholm | SE 171 76 | Sweden | Details | ||
| Novartis Investigative Site | Aarau | 5001 | Switzerland | Details | ||
| Novartis Investigative Site | Zuerich | 8091 | Switzerland | Details | ||
| Novartis Investigative Site | Songkhla | Hat Yai | 90110 | Thailand | Details | |
| Novartis Investigative Site | Bangkok | 10330 | Thailand | Details | ||
| Novartis Investigative Site | Truro | Cornwall | TR1 3LJ | United Kingdom | Details | |
| Novartis Investigative Site | Surrey | England | GU2 7XX | United Kingdom | Details | |
| Novartis Investigative Site | Northwood | Middlesex | HA6 2RN | United Kingdom | Details | |
| Novartis Investigative Site | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| Novartis Investigative Site | Leicester | LE1 5WW | United Kingdom | Details | ||
| Novartis Investigative Site | London | NW3 2QG | United Kingdom | Details | ||
| Novartis Investigative Site | Manchester | M20 4BX | United Kingdom | Details | ||
| Novartis Investigative Site | Middlesbrough | TS4 3BW | United Kingdom | Details | ||
| Novartis Investigative Site | Preston | PR2 9HT | United Kingdom | Details |