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NCT ID NCT03126916
Title Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Children's Oncology Group
Indications

neuroblastoma

nodular ganglioneuroblastoma

Therapies

Doxorubicin

131I-MIBG

Sargramostim

Etoposide

Melphalan

Busulfan

Isotretinoin

Vincristine Sulfate

Cisplatin

Cyclophosphamide

Thiotepa

Dexrazoxane

Lorlatinib

Carboplatin

Aldesleukin

Topotecan

Dinutuximab

Age Groups: adult | child
Covered Countries USA | CAN

Facility Status City State Zip Country Details
Children's Hospital of Alabama Suspended Birmingham Alabama 35233 United States Details
Phoenix Childrens Hospital Recruiting Phoenix Arizona 85016 United States Details
Arkansas Children's Hospital Recruiting Little Rock Arkansas 72202-3591 United States Details
Kaiser Permanente Downey Medical Center Recruiting Downey California 90242 United States Details
Loma Linda University Medical Center Recruiting Loma Linda California 92354 United States Details
Children's Hospital Los Angeles Suspended Los Angeles California 90027 United States Details
Mattel Children's Hospital UCLA Recruiting Los Angeles California 90095 United States Details
Valley Children's Hospital Recruiting Madera California 93636 United States Details
Kaiser Permanente-Oakland Recruiting Oakland California 94611 United States Details
Children's Hospital of Orange County Recruiting Orange California 92868 United States Details
Lucile Packard Children's Hospital Stanford University Recruiting Palo Alto California 94304 United States Details
University of California Davis Comprehensive Cancer Center Recruiting Sacramento California 95817 United States Details
Rady Children's Hospital - San Diego Recruiting San Diego California 92123 United States Details
Naval Medical Center -San Diego Recruiting San Diego California 92134 United States Details
UCSF Medical Center-Mission Bay Recruiting San Francisco California 94158 United States Details
Children's Hospital Colorado Recruiting Aurora Colorado 80045 United States Details
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center Recruiting Denver Colorado 80218 United States Details
Connecticut Children's Medical Center Recruiting Hartford Connecticut 06106 United States Details
Yale University Recruiting New Haven Connecticut 06520 United States Details
Alfred I duPont Hospital for Children Recruiting Wilmington Delaware 19803 United States Details
Children's National Medical Center Recruiting Washington District of Columbia 20010 United States Details
Golisano Children's Hospital of Southwest Florida Recruiting Fort Myers Florida 33908 United States Details
University of Florida Health Science Center - Gainesville Recruiting Gainesville Florida 32610 United States Details
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Recruiting Hollywood Florida 33021 United States Details
Nemours Children's Clinic-Jacksonville Recruiting Jacksonville Florida 32207 United States Details
University of Miami Miller School of Medicine-Sylvester Cancer Center Recruiting Miami Florida 33136 United States Details
Nicklaus Children's Hospital Recruiting Miami Florida 33155 United States Details
AdventHealth Orlando Recruiting Orlando Florida 32803 United States Details
Nemours Children's Hospital Recruiting Orlando Florida 32827 United States Details
Johns Hopkins All Children's Hospital Recruiting Saint Petersburg Florida 33701 United States Details
Saint Mary's Hospital Recruiting West Palm Beach Florida 33407 United States Details
Children's Healthcare of Atlanta - Egleston Recruiting Atlanta Georgia 30322 United States Details
Memorial Health University Medical Center Recruiting Savannah Georgia 31404 United States Details
Kapiolani Medical Center for Women and Children Recruiting Honolulu Hawaii 96826 United States Details
Saint Luke's Cancer Institute - Boise Recruiting Boise Idaho 83712 United States Details
Lurie Children's Hospital-Chicago Recruiting Chicago Illinois 60611 United States Details
University of Illinois Recruiting Chicago Illinois 60612 United States Details
University of Chicago Comprehensive Cancer Center Recruiting Chicago Illinois 60637 United States Details
Advocate Children's Hospital-Oak Lawn Recruiting Oak Lawn Illinois 60453 United States Details
Advocate Children's Hospital-Park Ridge Recruiting Park Ridge Illinois 60068 United States Details
Saint Jude Midwest Affiliate Recruiting Peoria Illinois 61637 United States Details
Southern Illinois University School of Medicine Recruiting Springfield Illinois 62702 United States Details
Riley Hospital for Children Recruiting Indianapolis Indiana 46202 United States Details
Blank Children's Hospital Recruiting Des Moines Iowa 50309 United States Details
University of Iowa/Holden Comprehensive Cancer Center Recruiting Iowa City Iowa 52242 United States Details
University of Kentucky/Markey Cancer Center Recruiting Lexington Kentucky 40536 United States Details
Children's Hospital New Orleans Recruiting New Orleans Louisiana 70118 United States Details
Ochsner Medical Center Jefferson Recruiting New Orleans Louisiana 70121 United States Details
Eastern Maine Medical Center Recruiting Bangor Maine 04401 United States Details
Maine Children's Cancer Program Recruiting Scarborough Maine 04074 United States Details
Sinai Hospital of Baltimore Recruiting Baltimore Maryland 21215 United States Details
Johns Hopkins University/Sidney Kimmel Cancer Center Recruiting Baltimore Maryland 21287 United States Details
Tufts Children's Hospital Active, not recruiting Boston Massachusetts 02111 United States Details
Massachusetts General Hospital Cancer Center Recruiting Boston Massachusetts 02114 United States Details
Dana-Farber Cancer Institute Recruiting Boston Massachusetts 02215 United States Details
C S Mott Children's Hospital Recruiting Ann Arbor Michigan 48109 United States Details
Wayne State University/Karmanos Cancer Institute Recruiting Detroit Michigan 48201 United States Details
Ascension Saint John Hospital Recruiting Detroit Michigan 48236 United States Details
Michigan State University Clinical Center Recruiting East Lansing Michigan 48824-7016 United States Details
Helen DeVos Children's Hospital at Spectrum Health Recruiting Grand Rapids Michigan 49503 United States Details
Bronson Methodist Hospital Recruiting Kalamazoo Michigan 49007 United States Details
Beaumont Children's Hospital-Royal Oak Recruiting Royal Oak Michigan 48073 United States Details
Children's Hospitals and Clinics of Minnesota - Minneapolis Recruiting Minneapolis Minnesota 55404 United States Details
University of Minnesota/Masonic Cancer Center Recruiting Minneapolis Minnesota 55455 United States Details
Mayo Clinic in Rochester Recruiting Rochester Minnesota 55905 United States Details
University of Mississippi Medical Center Recruiting Jackson Mississippi 39216 United States Details
Columbia Regional Recruiting Columbia Missouri 65201 United States Details
Children's Mercy Hospitals and Clinics Recruiting Kansas City Missouri 64108 United States Details
Washington University School of Medicine Recruiting Saint Louis Missouri 63110 United States Details
Mercy Hospital Saint Louis Recruiting Saint Louis Missouri 63141 United States Details
Children's Hospital and Medical Center of Omaha Recruiting Omaha Nebraska 68114 United States Details
University of Nebraska Medical Center Recruiting Omaha Nebraska 68198 United States Details
University Medical Center of Southern Nevada Recruiting Las Vegas Nevada 89102 United States Details
Sunrise Hospital and Medical Center Recruiting Las Vegas Nevada 89109 United States Details
Alliance for Childhood Diseases/Cure 4 the Kids Foundation Recruiting Las Vegas Nevada 89135 United States Details
Summerlin Hospital Medical Center Recruiting Las Vegas Nevada 89144 United States Details
Dartmouth Hitchcock Medical Center Recruiting Lebanon New Hampshire 03756 United States Details
Hackensack University Medical Center Recruiting Hackensack New Jersey 07601 United States Details
Morristown Medical Center Recruiting Morristown New Jersey 07960 United States Details
Saint Peter's University Hospital Recruiting New Brunswick New Jersey 08901 United States Details
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital Recruiting New Brunswick New Jersey 08903 United States Details
Newark Beth Israel Medical Center Suspended Newark New Jersey 07112 United States Details
Saint Joseph's Regional Medical Center Recruiting Paterson New Jersey 07503 United States Details
University of New Mexico Cancer Center Suspended Albuquerque New Mexico 87102 United States Details
Albany Medical Center Recruiting Albany New York 12208 United States Details
Montefiore Medical Center - Moses Campus Recruiting Bronx New York 10467 United States Details
Maimonides Medical Center Recruiting Brooklyn New York 11219 United States Details
Roswell Park Cancer Institute Recruiting Buffalo New York 14263 United States Details
NYU Winthrop Hospital Recruiting Mineola New York 11501 United States Details
The Steven and Alexandra Cohen Children's Medical Center of New York Recruiting New Hyde Park New York 11040 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone Recruiting New York New York 10016 United States Details
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center Recruiting New York New York 10032 United States Details
University of Rochester Suspended Rochester New York 14642 United States Details
Stony Brook University Medical Center Recruiting Stony Brook New York 11794 United States Details
State University of New York Upstate Medical University Recruiting Syracuse New York 13210 United States Details
New York Medical College Recruiting Valhalla New York 10595 United States Details
Mission Hospital Recruiting Asheville North Carolina 28801 United States Details
UNC Lineberger Comprehensive Cancer Center Recruiting Chapel Hill North Carolina 27599 United States Details
Carolinas Medical Center/Levine Cancer Institute Recruiting Charlotte North Carolina 28203 United States Details
Duke University Medical Center Recruiting Durham North Carolina 27710 United States Details
East Carolina University Recruiting Greenville North Carolina 27834 United States Details
Wake Forest University Health Sciences Recruiting Winston-Salem North Carolina 27157 United States Details
Sanford Broadway Medical Center Recruiting Fargo North Dakota 58122 United States Details
Cincinnati Children's Hospital Medical Center Recruiting Cincinnati Ohio 45229 United States Details
Rainbow Babies and Childrens Hospital Recruiting Cleveland Ohio 44106 United States Details
Cleveland Clinic Foundation Recruiting Cleveland Ohio 44195 United States Details
Nationwide Children's Hospital Recruiting Columbus Ohio 43205 United States Details
Dayton Children's Hospital Recruiting Dayton Ohio 45404 United States Details
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Recruiting Toledo Ohio 43606 United States Details
University of Oklahoma Health Sciences Center Recruiting Oklahoma City Oklahoma 73104 United States Details
Legacy Emanuel Children's Hospital Recruiting Portland Oregon 97227 United States Details
Lehigh Valley Hospital-Cedar Crest Recruiting Allentown Pennsylvania 18103 United States Details
Geisinger Medical Center Recruiting Danville Pennsylvania 17822 United States Details
Penn State Children's Hospital Recruiting Hershey Pennsylvania 17033 United States Details
Children's Hospital of Philadelphia Recruiting Philadelphia Pennsylvania 19104 United States Details
Children's Hospital of Pittsburgh of UPMC Recruiting Pittsburgh Pennsylvania 15224 United States Details
Rhode Island Hospital Recruiting Providence Rhode Island 02903 United States Details
Medical University of South Carolina Recruiting Charleston South Carolina 29425 United States Details
Prisma Health Richland Hospital Recruiting Columbia South Carolina 29203 United States Details
BI-LO Charities Children's Cancer Center Recruiting Greenville South Carolina 29605 United States Details
Sanford USD Medical Center - Sioux Falls Recruiting Sioux Falls South Dakota 57117-5134 United States Details
East Tennessee Childrens Hospital Recruiting Knoxville Tennessee 37916 United States Details
Saint Jude Children's Research Hospital Recruiting Memphis Tennessee 38105 United States Details
Vanderbilt University/Ingram Cancer Center Recruiting Nashville Tennessee 37232 United States Details
Dell Children's Medical Center of Central Texas Recruiting Austin Texas 78723 United States Details
Driscoll Children's Hospital Recruiting Corpus Christi Texas 78411 United States Details
Medical City Dallas Hospital Recruiting Dallas Texas 75230 United States Details
UT Southwestern/Simmons Cancer Center-Dallas Recruiting Dallas Texas 75390 United States Details
El Paso Children's Hospital Recruiting El Paso Texas 79905 United States Details
Cook Children's Medical Center Recruiting Fort Worth Texas 76104 United States Details
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Recruiting Houston Texas 77030 United States Details
Covenant Children's Hospital Recruiting Lubbock Texas 79410 United States Details
UMC Cancer Center / UMC Health System Recruiting Lubbock Texas 79415 United States Details
Children's Hospital of San Antonio Recruiting San Antonio Texas 78207 United States Details
Methodist Children's Hospital of South Texas Recruiting San Antonio Texas 78229 United States Details
University of Texas Health Science Center at San Antonio Recruiting San Antonio Texas 78229 United States Details
Primary Children's Hospital Recruiting Salt Lake City Utah 84113 United States Details
University of Vermont and State Agricultural College Recruiting Burlington Vermont 05405 United States Details
Virginia Commonwealth University/Massey Cancer Center Recruiting Richmond Virginia 23298 United States Details
Seattle Children's Hospital Recruiting Seattle Washington 98105 United States Details
Providence Sacred Heart Medical Center and Children's Hospital Recruiting Spokane Washington 99204 United States Details
Mary Bridge Children's Hospital and Health Center Recruiting Tacoma Washington 98405 United States Details
Madigan Army Medical Center Recruiting Tacoma Washington 98431 United States Details
West Virginia University Healthcare Recruiting Morgantown West Virginia 26506 United States Details
Saint Vincent Hospital Cancer Center Green Bay Recruiting Green Bay Wisconsin 54301 United States Details
University of Wisconsin Carbone Cancer Center Recruiting Madison Wisconsin 53792 United States Details
Marshfield Medical Center-Marshfield Recruiting Marshfield Wisconsin 54449 United States Details
Children's Hospital of Wisconsin Recruiting Milwaukee Wisconsin 53226 United States Details
British Columbia Children's Hospital Suspended Vancouver British Columbia V6H 3V4 Canada Details
CancerCare Manitoba Suspended Winnipeg Manitoba R3E 0V9 Canada Details
Janeway Child Health Centre Suspended Saint John's Newfoundland and Labrador A1B 3V6 Canada Details
IWK Health Centre Recruiting Halifax Nova Scotia B3K 6R8 Canada Details
McMaster Children's Hospital at Hamilton Health Sciences Suspended Hamilton Ontario L8N 3Z5 Canada Details
Kingston Health Sciences Centre Suspended Kingston Ontario K7L 2V7 Canada Details
Children's Hospital Suspended London Ontario N6A 5W9 Canada Details
Children's Hospital of Eastern Ontario Suspended Ottawa Ontario K1H 8L1 Canada Details
Hospital for Sick Children Suspended Toronto Ontario M5G 1X8 Canada Details
HIMA San Pablo Oncologic Hospital Active, not recruiting Caguas 00726 Puerto Rico Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field