Clinical Trial Detail


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NCT ID NCT03157128
Title Phase 1/2 Study of LOXO-292 in Patients With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)
Recruitment Recruiting
Gender both
Phase Phase Ib/II
Variant Requirements Yes
Sponsors Loxo Oncology, Inc.

thyroid gland cancer

thyroid gland medullary carcinoma


Advanced Solid Tumor



Age Groups: adult | senior
Covered Countries USA | ITA | GBR | FRA | ESP | DEU | CAN | AUS

Facility Status City State Zip Country Details
Mayo Clinic of Scottsdale Recruiting Scottsdale Arizona 85259 United States Details
City of Hope National Medical Center Recruiting Duarte California 91010 United States Details
University of California - San Diego Recruiting La Jolla California 92161 United States Details
UCLA Medical Center Recruiting Los Angeles California 90095 United States Details
Hoag Memorial Hospital Presbyterian Not yet recruiting Newport Beach California 92663 United States Details
Irvine Medical Center Recruiting Orange California 92868 United States Details
UCSF Medical Center at Mission Bay Recruiting San Francisco California 94115 United States Details
Kaiser Permanente Recruiting Santa Clara California 95051 United States Details
Kaiser Permanente Medical Center Recruiting Vallejo California 94589 United States Details
Sarah Cannon Research Institute at HealthONE Recruiting Denver Colorado 80218 United States Details
Yale Cancer Center Recruiting New Haven Connecticut 06510 United States Details
Johns Hopkins University Recruiting Washington District of Columbia 20016 United States Details
Mayo Clinic-Jacksonville Recruiting Jacksonville Florida 32224 United States Details
Memorial Hospital Pembroke Recruiting Pembroke Florida 33028 United States Details
Emory University Recruiting Atlanta Georgia 30322 United States Details
University of Chicago Medicine-Comprehensive Cancer Center Recruiting Chicago Illinois 60637 United States Details
Ochsner Clinic Foundation Recruiting New Orleans Louisiana 70121 United States Details
University of Maryland Medical Center Recruiting Baltimore Maryland 21201 United States Details
Massachusetts General Hospital Recruiting Boston Massachusetts 02114 United States Details
Dana-Farber Cancer Institute Recruiting Boston Massachusetts 02115 United States Details
University of Michigan Recruiting Ann Arbor Michigan 48109 United States Details
START Midwest Recruiting Grand Rapids Michigan 49546 United States Details
Mayo Clinic Recruiting Rochester Minnesota 55905 United States Details
Washington University Medical School Recruiting Saint Louis Missouri 63110 United States Details
Comprehensive Cancer Centers of Nevada Not yet recruiting Las Vegas Nevada 89169 United States Details
Roswell Park Cancer Center Recruiting Buffalo New York 14263 United States Details
NYU Langone Medical Center Recruiting New York New York 10016 United States Details
Memorial Sloan Kettering Cancer Center Recruiting New York New York 10065 United States Details
University of North Carolina Recruiting Chapel Hill North Carolina 27599 United States Details
Cleveland Clinic Recruiting Cleveland Ohio 44195 United States Details
Ohio State University Hospital Recruiting Columbus Ohio 43210 United States Details
Oregon Health and Science University Recruiting Portland Oregon 97239 United States Details
University of Pennsylvania Hospital Recruiting Philadelphia Pennsylvania 19104 United States Details
Sarah Cannon Research Institute SCRI Recruiting Nashville Tennessee 37203 United States Details
Vanderbilt University Medical Center Recruiting Nashville Tennessee 37232 United States Details
University of Texas Southwestern Medical Center at Dallas Recruiting Dallas Texas 75390 United States Details
University of Texas MD Anderson Cancer Center Recruiting Houston Texas 77030 United States Details
Huntsman Cancer Institute Recruiting Salt Lake City Utah 84112 United States Details
Virginia Cancer Specialists, PC Recruiting Fairfax Virginia 22031 United States Details
University of Wisconsin-Madison Hospital and Health Clinic Recruiting Madison Wisconsin 53792 United States Details
Royal North Shore Hospital Recruiting Saint Leonards New South Wales 2065 Australia Details
Peter MacCallum Cancer Centre Recruiting Melbourne Victoria 3000 Australia Details
British Columbia Cancer Agency Recruiting Vancouver British Columbia V5Z 4E6 Canada Details
Rigshospitalet Recruiting Copenhagen København Ø 2100 Denmark Details
Hôpital Européen Georges Pompidou Recruiting Paris Cedex 15 75908 France Details
Institut Bergonie Recruiting Bordeaux 33076 France Details
Centre Leon Berard Recruiting Lyon Cedex 08 69008 France Details
APHM Hôpital de la Timone Recruiting Marseille 13385 France Details
Institut du Cancer de Montpellier - Val d'aurelle Not yet recruiting Montpellier Cedex 5 34298 France Details
Gustave Roussy Recruiting Villejuif Cedex 94805 France Details
Universitätsklinikum Würzburg A. ö. R. Recruiting Würzburg Bayern 97080 Germany Details
Universitätsklinikum Köln Recruiting Köln Nordrhein-Westfalen 50937 Germany Details
Prince of Wales Hospital Recruiting Hong Kong Shatin, New Territories Hong Kong Details
Sheba Medical Center Recruiting Tel Hashomer Ramat Gan 5265601 Israel Details
Soroka Medical Center - Pediatric Outpatient Clinic Recruiting Beer-Sheva 8410101 Israel Details
Hadassah Medical Center Recruiting Jerusalem 91120 Israel Details
Istituto Nazionale dei Tumori Recruiting Milano Lombardie 20133 Italy Details
Nagoya University Hospital Recruiting Nagoya Aichi 466-8560 Japan Details
National Cancer Center Hospital East Recruiting Kashiwa Chiba 277-8577 Japan Details
Hokkaido University Hospital Recruiting Sapporo Hokkaido 060-8648 Japan Details
Hyogo Cancer Center Recruiting Akashi Hyogo 673-8558 Japan Details
Kanazawa University Hospital Recruiting Kanazawa Ishikawa 920-8641 Japan Details
Kindai University Hospital Recruiting Osaka Sayama-shi Osaka 589 8511 Japan Details
Shizuoka Cancer Center Recruiting Sunto-Gun Shizuoka 411-8777 Japan Details
National Cancer Center Hospital Recruiting Chuo-ku Tokyo 104-0045 Japan Details
The Cancer Institute Hospital of JFCR Recruiting Koto-ku Tokyo 135-8550 Japan Details
Tottori University Hospital Recruiting Yonago Tottori 683-0826 Japan Details
Kyushu Cancer Center Recruiting Fukuoka 811-1395 Japan Details
Okayama University Hospital Recruiting Okayama 700-8558 Japan Details
Osaka City General Hospital Recruiting Osaka 534-0021 Japan Details
National Cancer Center Recruiting Goyang-si Gyeonggi-do 10408 Korea, Republic of Details
Seoul National University Bundang Hospital Recruiting Seongnam Gyeonggi-do 13620 Korea, Republic of Details
Samsung Medical Center Recruiting Seoul Korea 06351 Korea, Republic of Details
Severance Hospital Recruiting Seoul 03722 Korea, Republic of Details
Asan Medical Center Recruiting Seoul 05505 Korea, Republic of Details
National Cancer Center Singapore Recruiting Singapore 169610 Singapore Details
Hospital Universitario Vall d'Hebron Recruiting Barcelona 08035 Spain Details
Fundacion Jimenez Diaz Recruiting Madrid 28040 Spain Details
Hospital Madrid Norte Sanchinarro Recruiting Madrid 28050 Spain Details
Kantonsspital Luzern Recruiting Luzern 16 6000 Switzerland Details
Taichung Veterans General Hospital Recruiting Taichung 40705, ROC Taiwan Details
National Taiwan University Hospital Recruiting Taipei 10002 Taiwan Details
Royal Marsden Hospital Recruiting Sutton Surrey SM2 5PT United Kingdom Details
*Shaded cells indicate that there was no data available from for the field