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| NCT ID | NCT03178851 |
| Title | Cobimetinib (Targeted Therapy) Plus Atezolizumab (Immunotherapy) in Participants With Advanced Melanoma Whose Cancer Has Worsened During or After Treatment With Previous Immunotherapy and Atezolizumab Monotherapy in Participants With Previously Untreated Advanced Melanoma |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ESP | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| HonorHealth Research Institute - Bisgrove | Scottsdale | Arizona | 85258 | United States | Details | |
| University of Colorado Hospital - Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Baylor University Medical Center | Dallas | Texas | 75231 | United States | Details | |
| Blacktown Hospital | Blacktown | New South Wales | 2148 | Australia | Details | |
| Melanoma Institute Australia | North Sydney | New South Wales | 2060 | Australia | Details | |
| Mid North Coast Cancer Institute | Port Macquarie | New South Wales | 2444 | Australia | Details | |
| Greenslopes Private Hospital; Clinic Pharmacy | Greenslopes | Queensland | 4120 | Australia | Details | |
| Flinders Medical Centre | Bedford Park | South Australia | 5042 | Australia | Details | |
| Peter Maccallum Cancer Centre | Melbourne | Victoria | 3000 | Australia | Details | |
| Alfred Hospital | Melbourne | Victoria | 3004 | Australia | Details | |
| University Clinical Centre of the Republic of Srpska | Banja Luka | 78000 | Bosnia and Herzegovina | Details | ||
| University Clinic Ctr Sarajevo | Sarajevo | 71 000 | Bosnia and Herzegovina | Details | ||
| Instituto de Ensino e Pesquisa Clinica do Ceara | Fortaleza | CE | 60130-241 | Brazil | Details | |
| Cenantron - Centro Avancado de Tratamento Oncologico | Belo Horizonte | MG | 30130-090 | Brazil | Details | |
| Instituto Nacional de Cancer - INCa; Oncologia | Rio de Janeiro | RJ | 20560-120 | Brazil | Details | |
| Hospital Sao Vicente de Paulo | Passo Fundo | RS | 99010-090 | Brazil | Details | |
| Hospital das Clinicas - UFRGS | Porto Alegre | RS | 90035-903 | Brazil | Details | |
| Hospital Sao Lucas - PUCRS | Porto Alegre | RS | 90610-000 | Brazil | Details | |
| Hospital Amaral Carvalho | Jau | SP | 17210-120 | Brazil | Details | |
| Cape Town Oncology Trials | Cape Town | 7570 | South Africa | Details | ||
| GVI Constantiaberg | Cape Town | 7800 | South Africa | Details | ||
| Johese Clinical Research | Centurion | 1692 | South Africa | Details | ||
| Cancercare | George | 6529 | South Africa | Details | ||
| Wits Clinical Research; Charlotte Maxeke Johannesburg Academic Hospital | Johannesburg | 2193 | South Africa | Details | ||
| Cancercare | Port Elizabeth | 6045 | South Africa | Details | ||
| Steve Biko Academic Hospital; Oncology | Pretoria | 0002 | South Africa | Details | ||
| Hospital Clinico Universitario de Santiago | Santiago de Compostela | LA Coruña | 15706 | Spain | Details | |
| Clínica Universidad de Navarra | Pamplona | Navarra | 31620 | Spain | Details | |
| Hospital Universitario Virgen Macarena | Seville | Sevilla | 41071 | Spain | Details | |
| Hospital Universitari Quiron Dexeus | Barcelona | 08028 | Spain | Details | ||
| Hospital Clinic I Provincial | Barcelona | 08036 | Spain | Details | ||
| MD Anderson Cancer Center | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Ramón y Cajal; Pharmacy | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario La Paz; Servicio de Oncologia | Madrid | 28046 | Spain | Details | ||
| Central Municipal Hospital - Uzhgorod State University | Uzhgorod | Chernihiv Governorate | 88017 | Ukraine | Details | |
| Public Institution: City Multispecialty Clinical Hospital #4 under Dnipropetrovsk Regional Council | Dnipropetrovsk | 49102 | Ukraine | Details | ||
| National Cancer Institute MOH of Ukraine | Kiev | 36022 | Ukraine | Details | ||
| Lviv State Oncology Regional Treatment and Diagnostic Centre | Lviv | 79031 | Ukraine | Details | ||
| Sumy Regional Clinical Onc Ctr | Sumy | 40005 | Ukraine | Details |