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NCT ID NCT03179436
Title Safety, Pharmacokinetics (PK), and Efficacy of MK-1308 in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)
Recruitment Active, not recruiting
Gender both
Phase Phase Ib/II
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications

Advanced Solid Tumor

central nervous system cancer

lung non-small cell carcinoma

lung small cell carcinoma

melanoma

Therapies

MK-1308 + Pembrolizumab

MK-1308

Age Groups: senior | adult
Covered Countries USA | ITA | FRA | ESP | CAN

Facility Status City State Zip Country Details
Banner MD Anderson Cancer Center ( Site 0013) Gilbert Arizona 85234 United States Details
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0005) Hackensack New Jersey 07601 United States Details
Tennessee Oncology Nashville ( Site 0004) Nashville Tennessee 37203 United States Details
South Texas Accelerated Research Therapeutics, LLC (START) ( Site 0001) San Antonio Texas 78229 United States Details
Inova Schar Cancer Institute ( Site 1001) Fairfax Virginia 22031-4867 United States Details
Blacktown Hospital. Western Sydney local health district ( Site 0009) Blacktown New South Wales 2148 Australia Details
Calvary Mater Newcastle ( Site 0025) Waratah New South Wales 2298 Australia Details
Melanoma Institute Australia ( Site 0017) Wollstonecraft New South Wales 2065 Australia Details
Gallipoli Medical Research Foundation-GMRF CTU ( Site 0019) Brisbane Queensland 4120 Australia Details
Cairns and Hinterland Hospital and Health Service ( Site 0020) Cairns Queensland 4870 Australia Details
Ashford Cancer Centre Research ( Site 0012) Kurralta Park South Australia 5037 Australia Details
Ballarat Health Services ( Site 0022) Ballarat Victoria 3350 Australia Details
Alfred Health ( Site 0018) Melbourne Victoria 3004 Australia Details
Sunnybrook Research Institute ( Site 1103) Toronto Ontario M4N 3M5 Canada Details
Princess Margaret Cancer Centre ( Site 1104) Toronto Ontario M5G 2M9 Canada Details
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 1102) Montreal Quebec H2X 0A9 Canada Details
Jewish General Hospital ( Site 1105) Montreal Quebec H3T 1E2 Canada Details
McGill University Health Centre ( Site 1101) Montreal Quebec H4A 3J1 Canada Details
Fundacion Arturo Lopez Perez ( Site 5601) Santiago Region M. De Santiago 7500921 Chile Details
Beijing Cancer hospital-Digestive Oncology ( Site 5001) Beijing Beijing 100142 China Details
Chongqing Cancer Hospital-Phase 1 Unite ( Site 5004) Chongqing Chongqing 400030 China Details
Sir Run Run Shaw Hospital-Medical Oncology ( Site 5003) Hangzhou Zhejiang 310016 China Details
Hopital La Timone ( Site 3303) Marseille Bouches-du-Rhone 13005 France Details
Institut Bergonie ( Site 3306) Bordeaux Gironde 33076 France Details
CHRU Lille - Hopital Claude Huriez ( Site 3302) Lille Nord 59037 France Details
CH Lyon Sud Hospices Civils de Lyon ( Site 3307) Pierre Benite Rhone 69495 France Details
Gustave Roussy ( Site 3305) Villejuif Val-de-Marne 94800 France Details
Regional General Hospital of Athens "Laiko" ( Site 3001) Athens Attiki 115 27 Greece Details
Rambam Medical Center ( Site 0003) Haifa 3109601 Israel Details
Hadassah Ein Karem Hebrew University Medical Center ( Site 0021) Jerusalem 9112001 Israel Details
Sheba Medical Center - Cancer Center ( Site 0002) Ramat-Gan 52621 Israel Details
Istituto Nazionale Tumori Fondazione Pascale ( Site 3903) Napoli 80131 Italy Details
IRCCS Istituto Oncologico Veneto ( Site 3905) Padova 35128 Italy Details
Policlinico Le Scotte - A.O. Senese ( Site 3907) Siena 53100 Italy Details
National Cancer Center Hospital East ( Site 0014) Kashiwa Chiba 277-8577 Japan Details
Hyogo Cancer Center ( Site 0015) Akashi Hyogo 673-8558 Japan Details
Asan Medical Center ( Site 0006) Seoul. Seoul 05505 Korea, Republic of Details
Seoul National University Hospital ( Site 0007) Seoul 03080 Korea, Republic of Details
Severance Hospital Yonsei University Health System ( Site 0008) Seoul 03722 Korea, Republic of Details
Samsung Medical Center ( Site 0010) Seoul 06351 Korea, Republic of Details
Canterbury District Health Board ( Site 0023) Christchurch Canterbury 8011 New Zealand Details
Auckland City Hospital ( Site 0016) Auckland 1023 New Zealand Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Oddzial Badan Wczesnych Faz ( Site 4801 Warszawa Mazowieckie 02-781 Poland Details
Szpital Kliniczny im. Heliodora Swiecickiego Uniwers Medyczn ( Site 4803) Poznan Wielkopolskie 60-780 Poland Details
Sandton Oncology Medical Group PTY LTD ( Site 2701) Johannesburg Gauteng 2196 South Africa Details
Cape Town Oncology Trials Pty Ltd ( Site 2704) Kraaifontein Western Cape 7570 South Africa Details
Cancercare Rondebosch Oncology ( Site 2706) Rondebosch Western Cape 7700 South Africa Details
Instituto Catalan de Oncologia ICO - Hospital Duran i Reynals ( Site 3403) Hospitalet de Llobregat Barcelona 08908 Spain Details
Onkologikoa - Instituto Oncologico de San Sebastian ( Site 3405) San Sebastian Gipuzkoa 20014 Spain Details
Hospital General Universitario de Valencia ( Site 3404) Valencia Valenciana, Comunitat 46014 Spain Details
Hospital Clinic i Provincial de Barcelona ( Site 3401) Barcelona 08036 Spain Details
Hospital Universitario Virgen de la Macarena ( Site 3402) Sevilla 41009 Spain Details
Skanes Universitetssjukhus Lund. ( Site 4601) Lund Skane Lan 221 85 Sweden Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field