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NCT ID NCT03213691
Title Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Recruitment Active, not recruiting
Gender both
Phase Phase II
Variant Requirements Yes
Sponsors National Cancer Institute (NCI)
Indications

Advanced Solid Tumor

histiocytosis

non-Hodgkin lymphoma

neuroblastoma

Therapies

Selumetinib

Age Groups: adult | child
Covered Countries USA

Facility Status City State Zip Country Details
Children's Hospital of Alabama Birmingham Alabama 35233 United States Details
Banner Children's at Desert Mesa Arizona 85202 United States Details
Phoenix Childrens Hospital Phoenix Arizona 85016 United States Details
Arkansas Children's Hospital Little Rock Arkansas 72202-3591 United States Details
Kaiser Permanente Downey Medical Center Downey California 90242 United States Details
Loma Linda University Medical Center Loma Linda California 92354 United States Details
Miller Children's and Women's Hospital Long Beach Long Beach California 90806 United States Details
Children's Hospital Los Angeles Los Angeles California 90027 United States Details
Mattel Children's Hospital UCLA Los Angeles California 90095 United States Details
Valley Children's Hospital Madera California 93636 United States Details
UCSF Benioff Children's Hospital Oakland Oakland California 94609 United States Details
Kaiser Permanente-Oakland Oakland California 94611 United States Details
Lucile Packard Children's Hospital Stanford University Palo Alto California 94304 United States Details
UCSF Medical Center-Mission Bay San Francisco California 94158 United States Details
Children's Hospital Colorado Aurora Colorado 80045 United States Details
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center Denver Colorado 80218 United States Details
Yale University New Haven Connecticut 06520 United States Details
Alfred I duPont Hospital for Children Wilmington Delaware 19803 United States Details
Children's National Medical Center Washington District of Columbia 20010 United States Details
University of Florida Health Science Center - Gainesville Gainesville Florida 32610 United States Details
Nemours Children's Clinic-Jacksonville Jacksonville Florida 32207 United States Details
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami Florida 33136 United States Details
Nicklaus Children's Hospital Miami Florida 33155 United States Details
Arnold Palmer Hospital for Children Orlando Florida 32806 United States Details
Nemours Children's Hospital Orlando Florida 32827 United States Details
Nemours Children's Clinic - Pensacola Pensacola Florida 32504 United States Details
Johns Hopkins All Children's Hospital Saint Petersburg Florida 33701 United States Details
Saint Joseph's Hospital/Children's Hospital-Tampa Tampa Florida 33607 United States Details
Saint Mary's Hospital West Palm Beach Florida 33407 United States Details
Children's Healthcare of Atlanta - Egleston Atlanta Georgia 30322 United States Details
Memorial Health University Medical Center Savannah Georgia 31404 United States Details
Kapiolani Medical Center for Women and Children Honolulu Hawaii 96826 United States Details
Saint Luke's Cancer Institute - Boise Boise Idaho 83712 United States Details
Lurie Children's Hospital-Chicago Chicago Illinois 60611 United States Details
University of Chicago Comprehensive Cancer Center Chicago Illinois 60637 United States Details
Saint Jude Midwest Affiliate Peoria Illinois 61637 United States Details
Riley Hospital for Children Indianapolis Indiana 46202 United States Details
Blank Children's Hospital Des Moines Iowa 50309 United States Details
University of Iowa/Holden Comprehensive Cancer Center Iowa City Iowa 52242 United States Details
Norton Children's Hospital Louisville Kentucky 40202 United States Details
Children's Hospital New Orleans New Orleans Louisiana 70118 United States Details
Ochsner Medical Center Jefferson New Orleans Louisiana 70121 United States Details
Eastern Maine Medical Center Bangor Maine 04401 United States Details
Sinai Hospital of Baltimore Baltimore Maryland 21215 United States Details
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287 United States Details
C S Mott Children's Hospital Ann Arbor Michigan 48109 United States Details
Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis Minnesota 55404 United States Details
University of Minnesota/Masonic Cancer Center Minneapolis Minnesota 55455 United States Details
Mayo Clinic in Rochester Rochester Minnesota 55905 United States Details
University of Mississippi Medical Center Jackson Mississippi 39216 United States Details
Children's Mercy Hospitals and Clinics Kansas City Missouri 64108 United States Details
Cardinal Glennon Children's Medical Center Saint Louis Missouri 63104 United States Details
Washington University School of Medicine Saint Louis Missouri 63110 United States Details
Mercy Hospital Saint Louis Saint Louis Missouri 63141 United States Details
Children's Hospital and Medical Center of Omaha Omaha Nebraska 68114 United States Details
University of Nebraska Medical Center Omaha Nebraska 68198 United States Details
University Medical Center of Southern Nevada Las Vegas Nevada 89102 United States Details
Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas Nevada 89135 United States Details
Summerlin Hospital Medical Center Las Vegas Nevada 89144 United States Details
Hackensack University Medical Center Hackensack New Jersey 07601 United States Details
Morristown Medical Center Morristown New Jersey 07960 United States Details
Saint Peter's University Hospital New Brunswick New Jersey 08901 United States Details
Roswell Park Cancer Institute Buffalo New York 14263 United States Details
The Steven and Alexandra Cohen Children's Medical Center of New York New Hyde Park New York 11040 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York New York 10016 United States Details
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York New York 10032 United States Details
Memorial Sloan Kettering Cancer Center New York New York 10065 United States Details
NYP/Weill Cornell Medical Center New York New York 10065 United States Details
University of Rochester Rochester New York 14642 United States Details
State University of New York Upstate Medical University Syracuse New York 13210 United States Details
Mission Hospital Asheville North Carolina 28801 United States Details
Carolinas Medical Center/Levine Cancer Institute Charlotte North Carolina 28203 United States Details
Novant Health Presbyterian Medical Center Charlotte North Carolina 28204 United States Details
Duke University Medical Center Durham North Carolina 27710 United States Details
Children's Hospital Medical Center of Akron Akron Ohio 44308 United States Details
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 United States Details
Cleveland Clinic Foundation Cleveland Ohio 44195 United States Details
Nationwide Children's Hospital Columbus Ohio 43205 United States Details
Dayton Children's Hospital Dayton Ohio 45404 United States Details
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Toledo Ohio 43606 United States Details
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 United States Details
Legacy Emanuel Children's Hospital Portland Oregon 97227 United States Details
Oregon Health and Science University Portland Oregon 97239 United States Details
Geisinger Medical Center Danville Pennsylvania 17822 United States Details
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 United States Details
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224 United States Details
BI-LO Charities Children's Cancer Center Greenville South Carolina 29605 United States Details
Sanford USD Medical Center - Sioux Falls Sioux Falls South Dakota 57117-5134 United States Details
East Tennessee Childrens Hospital Knoxville Tennessee 37916 United States Details
Saint Jude Children's Research Hospital Memphis Tennessee 38105 United States Details
Vanderbilt University/Ingram Cancer Center Nashville Tennessee 37232 United States Details
Dell Children's Medical Center of Central Texas Austin Texas 78723 United States Details
Medical City Dallas Hospital Dallas Texas 75230 United States Details
UT Southwestern/Simmons Cancer Center-Dallas Dallas Texas 75390 United States Details
Cook Children's Medical Center Fort Worth Texas 76104 United States Details
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston Texas 77030 United States Details
M D Anderson Cancer Center Houston Texas 77030 United States Details
Children's Hospital of San Antonio San Antonio Texas 78207 United States Details
Methodist Children's Hospital of South Texas San Antonio Texas 78229 United States Details
University of Texas Health Science Center at San Antonio San Antonio Texas 78229 United States Details
Primary Children's Hospital Salt Lake City Utah 84113 United States Details
University of Vermont and State Agricultural College Burlington Vermont 05405 United States Details
Children's Hospital of The King's Daughters Norfolk Virginia 23507 United States Details
Virginia Commonwealth University/Massey Cancer Center Richmond Virginia 23298 United States Details
Seattle Children's Hospital Seattle Washington 98105 United States Details
Providence Sacred Heart Medical Center and Children's Hospital Spokane Washington 99204 United States Details
Madigan Army Medical Center Tacoma Washington 98431 United States Details
West Virginia University Healthcare Morgantown West Virginia 26506 United States Details
University of Wisconsin Carbone Cancer Center Madison Wisconsin 53792 United States Details
Children's Hospital of Wisconsin Milwaukee Wisconsin 53226 United States Details
San Jorge Children's Hospital San Juan 00912 Puerto Rico Details
University Pediatric Hospital San Juan 00926 Puerto Rico Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field