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NCT ID NCT03221426
Title Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications

gastroesophageal junction adenocarcinoma

gastric adenocarcinoma

Therapies

Capecitabine + Cisplatin

Capecitabine + Cisplatin + Pembrolizumab

Cisplatin + Fluorouracil + Pembrolizumab

Cisplatin + Fluorouracil

Age Groups: adult | senior
Covered Countries USA | ITA | FRA | DEU | CAN | BEL

Facility Status City State Zip Country Details
City of Hope ( Site 0005) Duarte California 91010 United States Details
Yale Cancer Center ( Site 0016) New Haven Connecticut 06520 United States Details
Georgetown University ( Site 0015) Washington District of Columbia 20007 United States Details
Northwestern University - Robert H. Lurie Comprehensive Cancer Center ( Site 0018) Chicago Illinois 60611 United States Details
The University of Chicago Medical Center ( Site 0004) Chicago Illinois 60637 United States Details
Roswell Park Cancer Institute ( Site 0001) Buffalo New York 14263 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0019) New York New York 10016 United States Details
Memorial Sloan Kettering ( Site 0024) New York New York 10065 United States Details
Weill Cornell Medical Center ( Site 0023) New York New York 10065 United States Details
University of Rochester ( Site 0011) Rochester New York 14642 United States Details
Fox Chase Cancer Center ( Site 0006) Philadelphia Pennsylvania 19111 United States Details
Temple University Hospital ( Site 0026) Philadelphia Pennsylvania 19140 United States Details
University of Utah, Huntsman Cancer Institute ( Site 0012) Salt Lake City Utah 84112 United States Details
Virginia Cancer Specialists, PC ( Site 0010) Fairfax Virginia 22031 United States Details
Institut Jules Bordet ( Site 0480) Brussels Bruxelles-Capitale, Region De 1000 Belgium Details
Hopital Erasme ULB ( Site 0484) Brussels Bruxelles-Capitale, Region De 1070 Belgium Details
UCL Saint Luc ( Site 0479) Bruxelles Bruxelles-Capitale, Region De 1200 Belgium Details
Grand Hopital de Charleroi ( Site 0478) Charleroi Hainaut 6000 Belgium Details
CHU de Liege ( Site 0482) Liège Liege 4000 Belgium Details
CHU UCL Namur Site de Godinne ( Site 0485) Yvoir Namur 5530 Belgium Details
UZ Gent ( Site 0486) Gent Oost-Vlaanderen 9000 Belgium Details
UZ Leuven ( Site 0483) Leuven Vlaams-Brabant 3000 Belgium Details
AZ Groeninge ( Site 0481) Kortrijk West-Vlaanderen 8500 Belgium Details
Instituto do Cancer do Ceara ( Site 0311) Fortaleza Ceara 60430-230 Brazil Details
Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 0308) Porto Alegre Rio Grande Do Sul 90610-000 Brazil Details
CEPON - Centro de Pesquisas Oncologicas ( Site 0302) Florianopolis Santa Catarina 88034-000 Brazil Details
Fundacao Pio XII - Hospital de Cancer de Barretos ( Site 0301) Barretos Sao Paulo 14784-400 Brazil Details
Hospital de Base de Sao Jose de Rio Preto ( Site 0304) Sao Jose Rio Preto Sao Paulo 15090-000 Brazil Details
Instituto Nacional Do Cancer Jose Alencar Gomes Da Silva ( Site 0307) Rio de Janeiro 20230-130 Brazil Details
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0305) Sao Paulo 01246-000 Brazil Details
Hospital Israelita Albert Einstein ( Site 0309) Sao Paulo 05652-900 Brazil Details
Cross Cancer Institute ( Site 0033) Edmonton Alberta T6G 1Z2 Canada Details
Moncton Hospital - Horizon Health Network ( Site 0038) Moncton New Brunswick E1C 6Z8 Canada Details
Sunnybrook Research Institute ( Site 0032) Toronto Ontario M4N 3M5 Canada Details
CISSS de la Monteregie-Centre ( Site 0039) Greenfield Park Quebec J4V 2H1 Canada Details
CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0040) Montreal Quebec H1T 2M4 Canada Details
Jewish General Hospital ( Site 0034) Montreal Quebec H3T 1E2 Canada Details
CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0035) Sherbrooke Quebec J1H 5N4 Canada Details
CHU de Quebec - Hotel-Dieu de Quebec ( Site 0042) Quebec G1R 2J6 Canada Details
Instituto Clinico del Sur. ICOS ( Site 0290) Temuco Araucania 4810469 Chile Details
Hospital Regional Rancagua Libertador Bernardo O Higgins ( Site 0299) Rancagua Lbtdr Gen Bernardo O Higgins 2820000 Chile Details
Fundacion Arturo Lopez Perez FALP ( Site 0286) Santiago Region M. De Santiago 7500921 Chile Details
Pontificia Universidad Catolica de Chile ( Site 0285) Santiago Region M. De Santiago 8330032 Chile Details
Hospital Clinico Universidad de Chile ( Site 0287) Santiago Region M. De Santiago 8380456 Chile Details
Beijing Cancer Hospital ( Site 0221) Beijing Beijing 100142 China Details
Zhejiang Cancer Hospital ( Site 0231) Hangzhou Zhejiang 310022 China Details
Sir Run Run Shaw Hospital ( Site 0233) Hangzhou Zhejiang 430030 China Details
SA Pohja-Eesti Regionaalhaigla ( Site 0526) Tallinn Harjumaa 13419 Estonia Details
Hopital Prive Jean Mermoz ( Site 0462) Lyon Auvergne 69008 France Details
Institut Paoli Calmettes ( Site 0472) Marseille Bouches-du-Rhone 13009 France Details
CHU Reims - Hopital Robert Debre ( Site 0465) Reims Champagne-Ardenne 51092 France Details
CHU Brest - Institut de Cancerologie et d Hematologie ( Site 0474) Brest Finistere 29200 France Details
CHU Toulouse - Hopital Rangueil ( Site 0470) Toulouse Haute-Garonne 31059 France Details
Institut du Cancer de Montpellier ( Site 0473) Montpellier Herault 34298 France Details
Centre Eugene Marquis ( Site 0466) Rennes Ille-et-Vilaine 35042 France Details
Institut de Cancerologie de l Ouest Centre Rene Gauducheau ( Site 0469) Saint Herblain Loire-Atlantique 44805 France Details
CHRU Lille - Hopital Claude Huriez ( Site 0461) Lille Nord 59037 France Details
CHU Poitiers - Pole Regional de Cancerologie ( Site 0467) Poitiers Vienne 86021 France Details
CHU Hopital Saint Antoine ( Site 0471) Paris 75012 France Details
Institut Mutualiste Montsouris ( Site 0463) Paris 75014 France Details
Klinikum Esslingen GmbH ( Site 0453) Esslingen Baden-Wurttemberg 73730 Germany Details
Universitaetsklinikum Freiburg ( Site 0450) Freiburg Baden-Wurttemberg 79106 Germany Details
Klinikum der Universitaet in Muenchen ( Site 0446) Muenchen Bayern 81377 Germany Details
Medizinische Hochschule Hannover ( Site 0449) Hannover Niedersachsen 30625 Germany Details
Kliniken Essen Mitte Gmbh Evang. Huyssens Stiftung ( Site 0445) Essen Nordrhein-Westfalen 45136 Germany Details
Medizinische klinilk und Poliklinik Johannes Gutenberg Univ ( Site 0455) Mainz Rheinland-Pfalz 55131 Germany Details
Universitaetsklinikum Carl Gustav Carus der TU Dresden ( Site 0448) Dresden Sachsen 01307 Germany Details
Haematologisch-Onkologische Praxis Eppendorf Facharztzentrum Eppendorf - Hope ( Site 0454) Hamburg 20249 Germany Details
Integra Cancer Institute ( Site 0262) Guatemala 01010 Guatemala Details
Grupo Medico Angeles ( Site 0261) Guatemala 01015 Guatemala Details
Centro Medico Integral De Cancerología (CEMIC) ( Site 0260) Quetzaltenango 09002 Guatemala Details
Soroka University M.C ( Site 0385) Beer Sheva HaDarom 8410101 Israel Details
Meir medical center ( Site 0386) Kfar Saba HaMerkaz 4428164 Israel Details
Sourasky Medical Center. ( Site 0382) Tel-Aviv Tell Abib 6423906 Israel Details
Rambam Health Care Campus ( Site 0381) Haifa 31096 Israel Details
Hadassah Medical Center. Ein Kerem ( Site 0383) Jerusalem 9112001 Israel Details
Rabin-Medical Center ( Site 0384) Petah Tikva 4941492 Israel Details
Sheba Medical center ( Site 0387) Ramat Gan 5265601 Israel Details
IRCCS Istituto Oncologico Veneto ( Site 0431) Padova Abruzzo 35128 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0430) Milano Lombardia 20133 Italy Details
Istituto Clinico Humanitas Research Hospital ( Site 0432) Rozzano Milano 20089 Italy Details
IRCCS Policlinico San Donato ( Site 0433) San Donato Milanese Milano 20097 Italy Details
Azienda Ospedaliero Universitaria di Modena Policlinico ( Site 0429) Modena 41125 Italy Details
Seconda Universita Napoli ( Site 0436) Napoli 80131 Italy Details
A.O.U. Santa Maria della Misericordia di Udine ( Site 0434) Udine 33100 Italy Details
Aichi Cancer Center Hospital ( Site 0165) Nagoya Aichi 464-8681 Japan Details
National Cancer Center Hospital East ( Site 0178) Kashiwa Chiba 277-8577 Japan Details
National Hospital Organization Shikoku Cancer Center ( Site 0186) Matsuyama Ehime 791-0280 Japan Details
Hokkaido University Hospital ( Site 0160) Sapporo Hokkaido 060-8648 Japan Details
Hyogo Cancer Center ( Site 0182) Akashi Hyogo 673-8558 Japan Details
Kobe University Hospital ( Site 0188) Kobe Hyogo 650-0017 Japan Details
Kobe City Medical Center General Hospital ( Site 0181) Kobe Hyogo 650-0047 Japan Details
Ibaraki Prefectural Central Hospital ( Site 0177) Kasama Ibaraki 309-1793 Japan Details
Iwate Medical University Hospital ( Site 0184) Shiwa-gun Iwate 028-3695 Japan Details
St. Marianna University School of Medicine Hospital ( Site 0187) Kawasaki Kanagawa 216-8511 Japan Details
Kanagawa Cancer Center ( Site 0167) Yokohama Kanagawa 241-8515 Japan Details
Kansai Medical University Hospital ( Site 0190) Hirakata Osaka 573-1191 Japan Details
Osaka University Hospital ( Site 0162) Suita Osaka 565-0871 Japan Details
Osaka Medical College Hospital ( Site 0168) Takatsuki Osaka 569-8686 Japan Details
Saitama Cancer Center ( Site 0170) Kitaadachi-gun Saitama 362-0806 Japan Details
Shizuoka Cancer Center Hospital and Research Institute ( Site 0176) Sunto-gun Shizuoka 411-8777 Japan Details
Chiba Cancer Center ( Site 0180) Chiba 260-8717 Japan Details
National Hospital Organization Kyushu Cancer Center ( Site 0172) Fukuoka 811-1395 Japan Details
Kyushu University Hospital ( Site 0173) Fukuoka 812-8582 Japan Details
Gifu University Hospital ( Site 0166) Gifu 501-1194 Japan Details
Hiroshima City Hiroshima Citizens Hospital ( Site 0171) Hiroshima 730-8518 Japan Details
Kochi Health Sciences Center ( Site 0189) Kochi 781-8555 Japan Details
Kumamoto University Hospital ( Site 0164) Kumamoto 860-8556 Japan Details
Niigata Cancer Center Hospital ( Site 0169) Niigata 951-8566 Japan Details
Osaka International Cancer Institute ( Site 0161) Osaka 541-8567 Japan Details
Osaka General Medical Center ( Site 0159) Osaka 558-8558 Japan Details
National Cancer Center Hospital ( Site 0179) Tokyo 104-0045 Japan Details
Tokyo Metropolitan Komagome Hospital ( Site 0183) Tokyo 113-8677 Japan Details
The Cancer Institute Hospital of JFCR ( Site 0185) Tokyo 135-8550 Japan Details
Toyama Prefectural Central Hospital ( Site 0163) Toyama 930-8550 Japan Details
Chonnam National University Hwasun Hospital ( Site 0083) Hwasun Gun Jeonranamdo 58128 Korea, Republic of Details
Seoul National University Bundang Hospital ( Site 0085) Seongnam-si Kyonggi-do 13620 Korea, Republic of Details
Kyungpook National University Chilgok Hospital ( Site 0089) Daegu Taegu-Kwangyokshi 41404 Korea, Republic of Details
Gachon University Gil Medical Center ( Site 0087) Incheon 21565 Korea, Republic of Details
Korea University Anam Hospital ( Site 0084) Seoul 02841 Korea, Republic of Details
Seoul National University Hospital -SNUH- ( Site 0080) Seoul 03080 Korea, Republic of Details
Severance Hospital Yonsei University Health System ( Site 0081) Seoul 03722 Korea, Republic of Details
Asan Medical Center ( Site 0082) Seoul 05505 Korea, Republic of Details
Gangnam Severance Hospital ( Site 0088) Seoul 06273 Korea, Republic of Details
SMG-SNU BORAMAE Medical Center ( Site 0086) Seoul 07061 Korea, Republic of Details
Riga East Clinical University Hospital ( Site 0550) Riga 1079 Latvia Details
LSMUL Kauno Klinikos ( Site 0570) Kaunas 50161 Lithuania Details
Nacionalinis Vezio Institutas ( Site 0569) Vilnius 08406 Lithuania Details
Vilniaus Universiteto Ligonine Santaros Klinikos ( Site 0568) Vilnius 08460 Lithuania Details
Hospital Kuala Lumpur ( Site 0146) Kuala Lumpur 50586 Malaysia Details
University Malaya Medical Centre ( Site 0143) Kuala Lumpur 59100 Malaysia Details
St. Luke s Medical Center ( Site 0622) Quezon City National Capital Region 1102 Philippines Details
Wojewodzki Szpital Specjalistyczny we Wroclawiu ( Site 0358) Wroclaw Dolnoslaskie 51-124 Poland Details
Samodzielny Publiczny Szpital Kliniczny Nr 1 w Lublinie ( Site 0351) Lublin Lubelskie 20-080 Poland Details
Szpital Uniwersytecki w Krakowie ( Site 0352) Krakow Malopolskie 31-501 Poland Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0349) Warszawa Mazowieckie 02-034 Poland Details
Mazowiecki Szpital Onkologiczny ( Site 0363) Wieliszew Mazowieckie 05-135 Poland Details
Szpital Specjalistyczny w Koscierzynie Sp. z o.o. ( Site 0353) Koscierzyna Pomorskie 83-400 Poland Details
Beskidzkie Centrum Onkologii im. Jana Pawla II ( Site 0354) Bielsko-Biala Slaskie 43-300 Poland Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0361) Gliwice Slaskie 44-101 Poland Details
SPZOZ WSS nr 3 w Rybniku ( Site 0357) Rybnik Slaskie 44-200 Poland Details
Kaluga Regional Clinical Oncology Center ( Site 0345) Kaluga Kaluzskaja Oblast 248007 Russian Federation Details
SBHI Leningrad Regional Clinical Hospital ( Site 0496) Saint Petersburg Leningradskaya Oblast 194291 Russian Federation Details
National Medical and Surgical Center n.a. N.I.Pirogov ( Site 0338) Moscow Moskva 105203 Russian Federation Details
Blokhin National Medical Oncology ( Site 0494) Moscow Moskva 115478 Russian Federation Details
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 0344) Saint Petersburg Sankt-Peterburg 197758 Russian Federation Details
Leningrad Regional Oncology Center ( Site 0335) Saint-Petersburg Sankt-Peterburg 188663 Russian Federation Details
City clinical oncological dispensary ( Site 0336) Sankt-Petersburg Sankt-Peterburg 198255 Russian Federation Details
Tomsk Scientific Research Institute of Oncology ( Site 0337) Tomsk Tomskaya Oblast 634028 Russian Federation Details
National University Hospital ( Site 0095) Singapore Central Singapore 119074 Singapore Details
National Cancer Centre Singapore ( Site 0097) Singapore Central Singapore 169610 Singapore Details
Oncocare Cancer Centre ( Site 0096) Singapore Central Singapore 258499 Singapore Details
Taipei Medical University Shuang Ho Hospital ( Site 0068) New Taipei 235 Taiwan Details
National Cheng Kung University Hospital ( Site 0067) Tainan 704 Taiwan Details
National Taiwan University Hospital ( Site 0063) Taipei 10002 Taiwan Details
Mackay Memorial Hospital ( Site 0065) Taipei 104 Taiwan Details
Koo Foundation Sun Yat-Sen Cancer Center ( Site 0066) Taipei 11259 Taiwan Details
Chang Gung Medical Foundation. Linkou ( Site 0064) Taoyuan 333 Taiwan Details
City Clinical Hosp.4 of DCC ( Site 0325) Dnipro Dnipropetrovska Oblast 49102 Ukraine Details
MI Kryvyi Rih Oncology Dispensary of Dnipropetrovsk Regional Council ( Site 0589) Kryviy Rih Dnipropetrovska Oblast 50048 Ukraine Details
Ivano-Frankivsk Regional Oncology Clinical Dispensary ( Site 0321) Ivano-Frankivsk Ivano-Frankivska Oblast 76018 Ukraine Details
Communal non profit enterprise Regional Clinical Oncology Center ( Site 0591) Kharkiv Kharkivska Oblast 61070 Ukraine Details
National Cancer Institute of the MoH of Ukraine ( Site 0319) Kyiv Kyivska Oblast 03022 Ukraine Details
Kyiv City Clinical Oncology Center ( Site 0590) Kyiv Kyivska Oblast 03115 Ukraine Details
University Hospitals Bristol NHS Foundation Trust ( Site 0407) Bristol Bristol, City Of BS2 8ED United Kingdom Details
Ninewells Hospital and Medical School ( Site 0406) Dundee Dundee City DD1 9SY United Kingdom Details
Royal Free London NHS Foundation Trust ( Site 0403) London London, City Of NW3 2QG United Kingdom Details
The Royal Marsden Foundation Trust ( Site 0405) London London, City Of SW3 6JJ United Kingdom Details
Imperial College Healthcare NHS Trust ( Site 0402) London London, City Of W2 1NY United Kingdom Details
Royal Marsden NHS Foundation Trust ( Site 0400) Sutton Surrey SM2 5PT United Kingdom Details
The Christie NHS Foundation Trust ( Site 0397) Manchester M20 4BX United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field