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NCT ID NCT03302234
Title Study of Pembrolizumab Given With Ipilimumab or Placebo in Participants With Untreated Metastatic Non-small Cell Lung Cancer (MK-3475-598/KEYNOTE-598)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Merck Sharp & Dohme Corp.
Indications

lung non-small cell carcinoma

Therapies

Pembrolizumab

Ipilimumab + Pembrolizumab

Age Groups: adult | senior
Covered Countries USA | CAN

Facility Status City State Zip Country Details
Mayo Clinic Cancer Center ( Site 0007) Phoenix Arizona 85054 United States Details
Disney Family Cancer Center ( Site 0035) Burbank California 91505 United States Details
Pacific Cancer Care ( Site 0001) Monterey California 93940 United States Details
John Wayne Cancer Institute ( Site 0021) Santa Monica California 90404 United States Details
Florida Hospital Cancer Institute ( Site 0009) Orlando Florida 32804 United States Details
Mercy Health-Paducah Medical Oncology and Hematology ( Site 0018) Paducah Kentucky 42003 United States Details
New England Cancer Specialists ( Site 0019) Scarborough Maine 04074 United States Details
Boston Medical Center ( Site 0025) Boston Massachusetts 02118 United States Details
Lahey Hospital & Medical Center ( Site 0020) Burlington Massachusetts 01805 United States Details
Holy Name Medical Center ( Site 0022) Teaneck New Jersey 07666 United States Details
Icahn School of Medicine at Mount Sinai ( Site 0034) New York New York 10029 United States Details
The Ohio State University Wexner Medical Center ( Site 0016) Columbus Ohio 43210 United States Details
Mid Ohio Oncology/Hematology Inc. ( Site 0003) Columbus Ohio 43219 United States Details
Providence Cancer Institute, Franz Clinic - Eastside ( Site 0031) Portland Oregon 97213 United States Details
Greenville Health System ( Site 8010) Greenville South Carolina 29615 United States Details
University of Tennessee Erlanger Oncology & Hematology ( Site 0026) Chattanooga Tennessee 37403 United States Details
Tennessee Cancer Specialists ( Site 0017) Knoxville Tennessee 37909 United States Details
Texas Oncology-Arlington South ( Site 8006) Arlington Texas 76014 United States Details
Texas Oncology-Methodist Dallas Cancer Center ( Site 8000) Dallas Texas 75203 United States Details
Texas Oncology-Flower Mound ( Site 8007) Flower Mound Texas 75028 United States Details
Texas Oncology-Longview Cancer Center ( Site 8009) Longview Texas 75601 United States Details
Northwest Cancer Specialists, P.C. ( Site 8001) Vancouver Washington 98684 United States Details
Virginia Mason Memorial- North Star Lodge Cancer Center ( Site 0033) Yakima Washington 98902 United States Details
University of Wisconsin Carbone Cancer Center ( Site 0004) Madison Wisconsin 53792 United States Details
Medical College of Wisconsin Clinical Cancer Center ( Site 0027) Milwaukee Wisconsin 53226 United States Details
Centro de Investigaciones Clinicas - Clinica Viedma ( Site 0202) Viedma Rio Negro R8500ACE Argentina Details
Sanatorio Parque ( Site 0201) Rosario Santa Fe S2000DSV Argentina Details
Hospital Aleman ( Site 0208) Buenos Aires C1118AAT Argentina Details
Hospital Privado Centro Medico Cordoba ( Site 0206) Cordoba X5016KEH Argentina Details
Centro Oncologico Riojano Integral ( Site 0203) La Rioja F5300COE Argentina Details
Sanatorio Britanico ( Site 0205) Rosario S2000CVB Argentina Details
Instituto de Oncologia de Rosario ( Site 0200) Rosario S2000KZE Argentina Details
Centro Medico San Roque ( Site 0207) Tucuman T4000IAK Argentina Details
Mater Cancer Care Centre ( Site 2102) South Brisbane Queensland 4101 Australia Details
Fiona Stanley Hospital ( Site 2105) Perth Western Australia 6150 Australia Details
Chris OBrien Lifehouse ( Site 2100) Camperdown 2050 Australia Details
The Townsville Hospital ( Site 2103) Douglas 4814 Australia Details
St Vincents Hospital Melbourne ( Site 2101) Fitzroy 3065 Australia Details
Inst de Medicina Integral Professor Fernando Figueira- IMIP ( Site 0302) Recife Pernambuco 50070-550 Brazil Details
Clinica de Hematologia e Oncologia Viver Ltda ( Site 0305) Santa Maria Rio Grande Do Sul 97015-513 Brazil Details
Hospital Nossa Senhora da Conceicao ( Site 0306) Porto Alegre RS 91350-200 Brazil Details
Instituto do Cancer de Sao Paulo - ICESP ( Site 0300) Sao Paulo SP 01246-000 Brazil Details
Hospital Alemao Oswaldo Cruz ( Site 0311) Sao Paulo SP 01323-020 Brazil Details
Escola Paulista de Medicina - UNIFESP ( Site 0304) Sao Paulo SP 04024-002 Brazil Details
Fundacao Pio XII - Hospital de Cancer de Barretos ( Site 0312) Barretos 14784-400 Brazil Details
CEPON Centro de Pesquisa Oncológicas ( Site 0307) Florianopolis 88034-000 Brazil Details
Hospital do Servidor Publico do Estado ( Site 0308) Sao Paulo 04039-004 Brazil Details
Tom Baker Cancer Centre ( Site 0119) Calgary Alberta T2N 4N2 Canada Details
CancerCare Manitoba ( Site 0106) Winnipeg Manitoba R3E 0V9 Canada Details
CIUSSS du Saguenay-Lac-St-Jean ( Site 0115) Chicoutimi Quebec G7H 5H6 Canada Details
CISSS de la Monteregie-Centre ( Site 0100) Greenfield Park Quebec J4V 2H1 Canada Details
CISSS-CA Hotel-Dieu de Levis ( Site 0108) Levis Quebec G6V 3Z1 Canada Details
CIUSSS Ouest de l'Ile - St-Mary's Hospital ( Site 0107) Montreal Quebec H3T 1M5 Canada Details
St-Jerome Medical Research Inc ( Site 0113) St-Jerome Quebec J7Z 5T3 Canada Details
Clinica Universidad Catolica del Maule ( Site 0413) Talca El Maule 3465584 Chile Details
Soc. Prosalud Montes y Orlandi Ltda (Orlandi Oncologia) ( Site 0401) Santiago 7500006 Chile Details
Pontificia Universidad Catolica de Chile ( Site 0404) Santiago 8330032 Chile Details
Instituto Nacional del Cancer ( Site 0406) Santiago 8380455 Chile Details
Hospital Clinico Vina del Mar ( Site 0400) Vina del Mar 2520000 Chile Details
Hospital Pablo Tobon Uribe ( Site 0505) Medellin Antioquia 050034 Colombia Details
Centro de Investigacion Clinica del Country ( Site 0500) Bogota 110221 Colombia Details
Clinica Colsanitas S.A. Sede Clinica Universitaria Colombia ( Site 0506) Bogota 110311 Colombia Details
Oncomedica S.A. ( Site 0502) Monteria 230002 Colombia Details
Instituto Cancerologico de Narino Ltda ( Site 0504) Pasto 520001 Colombia Details
Hopital Nord du Marseille ( Site 0808) Marseille Cedex 20 13015 France Details
Institut Bergonie ( Site 0803) Bordeaux 33076 France Details
CHU de Brest. Hopital Morvan ( Site 0800) Brest 29200 France Details
Centre Hopitalier Intercommunal Creteil ( Site 0802) Creteil 94010 France Details
Centre Hospitalier Le Mans ( Site 0804) Le Mans 72037 France Details
C.H.R.U de Lille - Hopital Calmette ( Site 0805) Lille 59037 France Details
Hopital Tenon ( Site 0810) Paris 75020 France Details
Nouvel Hopital Civil ( Site 0809) Strasbourg 67091 France Details
CHU de Toulouse - Hopital Larrey ( Site 0801) Toulouse 31059 France Details
Evangelische Lungenklinik Berlin ( Site 0903) Berlin 13125 Germany Details
Vivantes Klinikum Spandau ( Site 0910) Berlin 13585 Germany Details
HELIOS Klinikum Emil von Behring ( Site 0905) Berlin 14165 Germany Details
SRH Waldklinikum Gera GmbH ( Site 0907) Gera 07548 Germany Details
LungenClinic Grosshansdorf GmbH ( Site 0908) Grosshansdorf 22927 Germany Details
Universitaetsklinikum Heidelberg ( Site 0900) Heidelberg 69126 Germany Details
Universitaetsklinikum Leipzig ( Site 0919) Leipzig 04103 Germany Details
Universitaetsklinikum Schleswig Holstein. ( Site 0918) Luebeck 23538 Germany Details
Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 1502) Budapest 1121 Hungary Details
Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 1506) Budapest 1122 Hungary Details
Orszagos Onkologiai Intezet ( Site 1509) Budapest 1122 Hungary Details
Debreceni Egyetem Klinikai Kozpont ( Site 1511) Debrecen 4032 Hungary Details
Veszprem Megyei Tudogyogyintezet ( Site 1503) Farkasgyepu 8582 Hungary Details
Petz Aladar Megyei Oktato Korhaz ( Site 1505) Gyor 9024 Hungary Details
Bekes Megyei Pandy Kalman Korhaz. ( Site 1507) Gyula 5700 Hungary Details
Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz ( Site 1504) Szekesfehervar 8000 Hungary Details
Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet ( Site 1501) Szolnok 5000 Hungary Details
Beaumont Hospital ( Site 1312) Dublin D09 V2N0 Ireland Details
St James Hospital ( Site 1401) Dublin Dublin 8 Ireland Details
University Hospital Limerick ( Site 1403) Limerick V94 F858 Ireland Details
IRCCS Casa Sollievo della Sofferenza ( Site 1009) San Giovanni Rotondo (FG) Foggia 71013 Italy Details
Humanitas Research Hospital ( Site 1004) Rozzano Milano 20089 Italy Details
Ospedale Mater Salutis ( Site 1005) Legnago Verona 37045 Italy Details
ASST Spedali Civili ( Site 1001) Brescia 25123 Italy Details
Istituto Europeo di Oncologia ( Site 1007) Milano 20141 Italy Details
Ospedale San Gerardo ASST Monza ( Site 1002) Monza 20900 Italy Details
AORN dei Colli Plesso Monaldi ( Site 1003) Napoli 80131 Italy Details
Ospedale Santa Maria della Misericordia ( Site 1008) Perugia 06132 Italy Details
Seoul National University Hospital ( Site 2303) Seoul 03080 Korea, Republic of Details
Severance Hospital Yonsei University Health System ( Site 2300) Seoul 03722 Korea, Republic of Details
Asan Medical Center ( Site 2302) Seoul 05505 Korea, Republic of Details
Samsung Medical Center ( Site 2301) Seoul 06351 Korea, Republic of Details
Pauls Stradins Clinical University Hospital ( Site 1100) Riga 1002 Latvia Details
Riga East Clinical University Hospital ( Site 1111) Riga 1079 Latvia Details
Hospital Civil de Guadalajara Fray Antonio Alcalde ( Site 0603) Guadalajara Jalisco 44200 Mexico Details
Avix Investigacion Clinica S.C. ( Site 0600) Monterrey N.l. 64710 Mexico Details
Medical Care and Research S.A. de C.V. ( Site 0602) Merida Yucatan 97070 Mexico Details
Grupo Medico Camino SC ( Site 0607) Ciudad de Mexico 03310 Mexico Details
Medica Sur S.A.B de C.V. ( Site 0608) Mexico City 14050 Mexico Details
Oncologica de Puebla SA de CV ( Site 0606) Puebla 72530 Mexico Details
Hospital Nacional Guillermo Almenara Irigoyen ( Site 0705) La Victoria Lima 15033 Peru Details
Centro Especializado de Enfermedades Neoplasicas SRL-CEEN SRL ( Site 0710) Arequipa 04000 Peru Details
Instituto Regional de Enfermedades Neoplasicas del Sur IRENSUR ( Site 0704) Arequipa 04000 Peru Details
Clinica Internacional Sede San Borja ( Site 0701) Lima 15036 Peru Details
Hospital Nacional Cayetano Heredia ( Site 0706) Lima 15102 Peru Details
Clinica Peruano Americana S.A. ( Site 0703) Trujillo 13007 Peru Details
Dolnoslaskie Centrum Onkologii. ( Site 1616) Wroclaw Dolnoslaskie 53-413 Poland Details
Szpital Wojewodzki w Koszalinie im. Mikolaja Kopernika ( Site 1614) Koszalin Zachodniopomorskie 75-581 Poland Details
Powiatowe Centrum Zdrowia w Brzezinach ( Site 1615) Brzeziny 95-060 Poland Details
Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 1609) Bydgoszcz 85-796 Poland Details
Przychodnia Lekarska Komed ( Site 1602) Konin 62-500 Poland Details
Samodzielny Publiczny Zespol Gruzlicy i Chorob Pluc ( Site 1607) Olsztyn 10-357 Poland Details
MED-POLONIA Sp. z o.o. ( Site 1605) Poznan 60-693 Poland Details
Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie ( Site 1600) Warszawa 02-781 Poland Details
Universitas Annex National Hospital ( Site 1800) Bloemfontein Free State 9301 South Africa Details
Clinton Onclogy Clinic ( Site 1804) Alberton Gauteng 1448 South Africa Details
Wilgers Oncology Centre ( Site 1808) Pretoria Gauteng 0081 South Africa Details
Vincent Pallotti Hospital ( Site 1811) Cape Town 7405 South Africa Details
University of Stellenbosch and Tygerberg Hospital ( Site 1810) Cape Town 8000 South Africa Details
Dr G.A. Landers Specialist Oncologist ( Site 1803) Durban 4001 South Africa Details
Charlotte Maxeke Johannesburg Academic Hospital ( Site 1806) Johannesburg 2193 South Africa Details
Sandton Oncology Medical Group PTY LTD ( Site 1807) Johannesburg 2196 South Africa Details
GVI Oncology Clinical Research Centre ( Site 1802) Kraaifontein 7570 South Africa Details
Hospital Germans Trias i Pujol ( Site 1207) Badalona Barcelona 08916 Spain Details
Hospital Duran i Reynals ( Site 1201) Hospitalet de Llobregat Barcelona 08908 Spain Details
Hospital San Pedro de Alcantara ( Site 1208) Caceres Extremadura 10003 Spain Details
Hospital Universitario Insular de Gran Canaria ( Site 1203) Las Palmas de Gran Canaria Gran Canaria 35001 Spain Details
Hospital Universitari Vall d Hebron ( Site 1211) Barcelona 08035 Spain Details
Hospital Fundacion Jimenez Diaz - Clin. Concepcion ( Site 1209) Madrid 28040 Spain Details
Hospital Universitario Virgen del Rocio ( Site 1200) Sevilla 41013 Spain Details
Changhua Christian Hospital ( Site 2406) Changhua 50006 Taiwan Details
Chang Gung Medical Foundation - Kaohsiung ( Site 2404) Kaohsiung 833 Taiwan Details
China Medical University Hospital ( Site 2403) Taichung 404 Taiwan Details
National Cheng Kung University Hospital ( Site 2401) Tainan 70457 Taiwan Details
National Taiwan University Hospital ( Site 2400) Taipei 10048 Taiwan Details
Mackay Memorial Hospital ( Site 2405) Taipei 104 Taiwan Details
Chang Gung Memorial Hospital - Linkou Branch ( Site 2402) Taoyuan 33305 Taiwan Details
Ramathibodi Hospital. ( Site 2563) Ratchthevee Bangkok 10400 Thailand Details
Bangkok Hospital Chiangmai ( Site 2560) Mueang Chiang Mai 50000 Thailand Details
Chulalongkorn Hospital ( Site 2561) Bangkok 10330 Thailand Details
Pramongkutklao Hospital ( Site 2564) Bangkok 10400 Thailand Details
Siriraj Hospital ( Site 2562) Bangkok 10700 Thailand Details
Khon Kaen University ( Site 2565) Khon Kaen 40002 Thailand Details
Acibadem Adana Hastanesi ( Site 1904) Adana 01130 Turkey Details
Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 1908) Ankara 06100 Turkey Details
Uludag Universitesi Tip Fakultesi ( Site 1914) Bursa 16059 Turkey Details
Ankara Sehir Hastanesi ( Site 1903) Cankaya - Ankara 06490 Turkey Details
Trakya Uni. Tip Fakultesi ( Site 1911) Edirne 22030 Turkey Details
Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 1906) Istanbul 34098 Turkey Details
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi ( Site 1912) Istanbul 34899 Turkey Details
Ege Universitesi Tip Fakultesi Hastanesi ( Site 1901) Izmir 35100 Turkey Details
Medical Park Izmir Hospital ( Site 1900) Izmir 35575 Turkey Details
Kocaeli Universitesi Tip Fakultesi ( Site 1909) Kocaeli 41380 Turkey Details
Inonu Universitesi Tip Fakultesi ( Site 1907) Malatya 44280 Turkey Details
Karadeniz Teknik Universitesi ( Site 1910) Trabzon 61080 Turkey Details
MI Kryviy Rih Center of Dnipropetrovsk Regional Council ( Site 2005) Kryviy Rih Dnipropetrovsk Region 50048 Ukraine Details
Cherkasy Regional Hospital ( Site 2020) Cherkasy 18009 Ukraine Details
Regional Clinical Onco Dispensary_ State Medical University ( Site 2012) Chernivtsy 58013 Ukraine Details
Dnipropetrovsk City Multidiscipline Clinical Hosp.4 of DRC ( Site 2000) Dnipropetrovsk 49102 Ukraine Details
MI Prykarpatskyi Clinical Oncology Centrum ( Site 2009) Ivano-Frankivsk 76018 Ukraine Details
PP PPC Acinus Medical and Diagnostic Centre ( Site 2002) Kropyvnytskyi 25006 Ukraine Details
National Cancer Institute of the MoH of Ukraine ( Site 2015) Kyiv 03002 Ukraine Details
Kyiv City Clinical Oncological Center ( Site 2014) Kyiv 03115 Ukraine Details
Lviv State Oncology Regional Treatment and Diagnostic Center ( Site 2003) Lviv 79031 Ukraine Details
MI Odessa Regional Oncological Centre ( Site 2004) Odesa 65055 Ukraine Details
Royal Cornwall Hospital ( Site 1325) Truro Cornwall TR1 3LJ United Kingdom Details
The Royal Marsden NHS Foundation Trust. ( Site 1326) Sutton Surrey SM2 5PT United Kingdom Details
Belfast City Hospital ( Site 1302) Belfast BT9 7AB United Kingdom Details
Royal Free NHS Foundation Trust ( Site 1324) London NW3 2QG United Kingdom Details
St. Georges University Hospital NHS Foundation Trust ( Site 1321) London SW17 0QT United Kingdom Details
The Royal Marsden NHS Foundation Trust.. ( Site 1327) London SW3 6JJ United Kingdom Details
The Christie NHS Foundation Trust ( Site 1301) Manchester M20 4BX United Kingdom Details
Mount Vernon Cancer Centre ( Site 1307) Northwood HA6 2RN United Kingdom Details
Royal Wolverhampton Hospitals NHS Trust ( Site 1323) Wolverhampton WV10 0QP United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field