Clinical Trial Detail


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NCT ID NCT03322540
Title Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)
Recruitment Completed
Gender both
Phase Phase II
Variant Requirements Yes
Sponsors Incyte Corporation

lung non-small cell carcinoma



Epacadostat + Pembrolizumab

Age Groups: adult | senior
Covered Countries USA | ITA | ESP | CAN

Facility Status City State Zip Country Details
Pacific Cancer Medical Center, Inc. Anaheim California 92801 United States Details
Innovative Clinical Research Institute Whittier California 90603 United States Details
Florida Cancer Specialists (South Region) Fort Myers Florida 33916 United States Details
Florida Cancer Specialists (North Region) Saint Petersburg Florida 33705 United States Details
Southeastern Regional Medical Center, Inc. Newnan Georgia 30265 United States Details
Anne Arundel Health System Research Institute Annapolis Maryland 21401 United States Details
Weinberg Cancer Institute at Franklin Square Baltimore Maryland 21237 United States Details
Maryland Oncology Hematology, P.A. Rockville Maryland 20850 United States Details
UMass Memorial Medical Center Worcester Massachusetts 01655 United States Details
Minnesota Oncology Hematology, PA Coon Rapids Minnesota 55433 United States Details
Nebraska Cancer Specialists Omaha Nebraska 68130 United States Details
Allegheny General Hospital Pittsburgh Pennsylvania 15224 United States Details
Tennessee Oncology, PLLC/The Sarah Cannon Research Institute Chattanooga Tennessee 37404 United States Details
Tennessee Oncology, PLLC/The Sarah Cannon Research Institute Nashville Tennessee 37203 United States Details
Texas Oncology-South Austin Austin Texas 78745 United States Details
Austin Health-Austin Hospital Heidelberg Victoria 3084 Australia Details
St John of God Murdoch Medical Clinic Murdoch Western Australia 6150 Australia Details
Cross Cancer Institute Edmonton Alberta T6G 1Z2 Canada Details
Moncton Hospital - Horizon Health Network Moncton New Brunswick E1C 6Z8 Canada Details
William Osler Health System Brampton Ontario L6R 3J7 Canada Details
Cancer Centre of Southeastern Ontario at Kingston General Hospital Kingston Ontario K7L 2V7 Canada Details
Sault Area Hospital Sault Ste Marie Ontario P6B 0A8 Canada Details
Rigshospitalet Copenhagen 2100 Denmark Details
Regionshospitalet Herning Herning 7400 Denmark Details
Odense Universitetshospital Odense 5000 Denmark Details
SA Tartu Ulikooli Kliinikum Tartu 51014 Estonia Details
Galway University Hospital Galway Connacht H91 YR71 Ireland Details
St Vincents University Hospital Dublin Dublin 4 Ireland Details
Soroka Medical Center Beer Sheva 8457108 Israel Details
Rambam Medical Center Haifa 31096 Israel Details
Meir Medical Center Kfar Saba 4428164 Israel Details
Rabin Medical Center Petah Tikva 4941492 Israel Details
Chaim Sheba Medical Center Ramat Gan 52621 Israel Details
IRCCS A.O.U. San Martino - IST Genova 16132 Italy Details
Policlinico Universitario Agostino Gemelli Roma 00168 Italy Details
National Hospital Organization Nagoya Medical Center Nagoya Aichi 460-0001 Japan Details
National Hospital Organization Shikoku Cancer Center Matsuyama Ehime 791-0280 Japan Details
Kurume University Hospital Kurume Fukuoka 830-0011 Japan Details
Kanazawa University Hospital Kanazawa Ishikawa 920-8641 Japan Details
Kanagawa Cancer Center Yokohama Kanagawa 241-8515 Japan Details
Sendai Kousei Hospital Sendai Miyagi 980-0873 Japan Details
Kansai Medical University Hospital Hirakata Osaka 573-1191 Japan Details
Kindai University Hospital Osakasayama Osaka 589-8511 Japan Details
Shizuoka Cancer Center Nagaizumi-chō Shizuoka Prefecture 411-8777 Japan Details
National Hospital Organization Kyushu Cancer Center Fukuoka 811-1395 Japan Details
Kyushu University Hospital Fukuoka 812-8582 Japan Details
Niigata Cancer Center Hospital Niigata 951-8566 Japan Details
Okayama University Hospital Okayama 700-8558 Japan Details
National Cancer Center Hospital Tokyo 104-0045 Japan Details
Nippon Medical School Hospital Tokyo 113-8603 Japan Details
The Cancer Institute Hospital of JFCR Tokyo 135-8550 Japan Details
Wakayama Medical University Hospital Wakayama 641-8509 Japan Details
Chungbuk National University Hospital Cheongju si Chungcheongbuk Do 28644 Korea, Republic of Details
Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do 13620 Korea, Republic of Details
Gacheon University Gil Medical Center Incheon 21565 Korea, Republic of Details
Hospital Tengku Ampuan Afzan Kuantan Pahang 25100 Malaysia Details
Institut Kanser Negara - National Cancer Institute Putrajaya Wilayah Persekutuan 62250 Malaysia Details
University Malaya Medical Centre Kuala Lumpur 59100 Malaysia Details
Pantai Hospital Kuala Lumpur Kuala Lumpur Malaysia Details
Sarawak General Hospital Kuching Malaysia Details
Swietokrzyskie Centrum Onkologii SPZOZ Kielce Swietokrzyskie 25-734 Poland Details
Centrum Onkologii im. Prof. Franciszka Lukaszczyka Bydgoszcz 85-796 Poland Details
Centrum Onkologii. Instytut im. Marii Sklodowskiej-Curie Gliwice 44-101 Poland Details
Swietokrzyskie Centrum Onkologii SPZOZ Kielce 25-734 Poland Details
Przychodnia Lekarska Komed Konin 62-500 Poland Details
Samodzielny Publiczny Zespol Gruzlicy i Chorob Pluc Olsztyn 10-357 Poland Details
Wojewodzki Szpital im. Zofii z Zamoyskich Tarnowskiej w Tarnobrzegu Tarnobrzeg 39-400 Poland Details
Centrum Onkologii-Instytut im. Marii Sklodowskiej-Curie Warszawa 02-781 Poland Details
Belgorod Regional Oncology Dispensary Belgorod 308010 Russian Federation Details
Central Clinical Hospital with polyclinic Moscow 121359 Russian Federation Details
Moscow Research Oncology Institute named after P.A. Hertsen Moscow 125284 Russian Federation Details
SBHI Leningrad Regional Clinical Hospital Saint Petersburg 194291 Russian Federation Details
SBHI Samara Regional Clinical Oncology Dispensary Samara 443031 Russian Federation Details
Republican Clinical Oncology Dispensary of Republic of Bashkortostan Ufa 450054 Russian Federation Details
Hospital Alvaro Cunqueiro Vigo Pontevedra 36312 Spain Details
Hospital General de Alicante Alicante 03010 Spain Details
Hospital del Mar Barcelona 8003 Spain Details
Hospital Clinico San Carlos Madrid 28040 Spain Details
Hospital Universitario 12 de Octubre Madrid 28041 Spain Details
Hospital Universitario Virgen Macarena Sevilla 41009 Spain Details
Hospital Clinico de Valencia Valencia 46010 Spain Details
Oncological Institute of Southern Switzerland Bellinzona 6500 Switzerland Details
Inselspital Universitatsspital Bern Bern 3010 Switzerland Details
Hopitaux Universitaires de Geneve HUG. Geneva 1211 Switzerland Details
Kantonsspital Winterthur Winterthur 8401 Switzerland Details
Universitaetsspital Zuerich Zuerich 8091 Switzerland Details
Basken Uni. Adana Dr.Turgut Noyan Uygulama ve Arastirma Merkezi Adana 01120 Turkey Details
Ankara University Medical Faculty Ankara 06100 Turkey Details
Akdeniz Universitesi Tip Fakultesi Antalya 07059 Turkey Details
Erciyes Universitesi Tip Fakultesi Kayseri 38039 Turkey Details
Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi Konya 42080 Turkey Details
MI Kryviy Rih Center of Dnipropetrovsk Regional Council Kryvyi Rih Dnipropetrovsk Region 50048 Ukraine Details
Dnipropetrovsk City Multidiscipline Clinical Hosp.4 of DRC Dnipropetrovsk 49102 Ukraine Details
Grigoriev Institute for medical Radiology NAMS of Ukraine Kharkiv 61024 Ukraine Details
PP PPC Acinus Medical and Diagnostic Centre Kirovohrad 25001 Ukraine Details
Kyiv City Clinical Oncological Center Kyiv 03115 Ukraine Details
Dobryi Prognoz Kyiv 03126 Ukraine Details
Volyn Regional Oncological Dispensary Lutsk 43018 Ukraine Details
MI Odessa Regional Oncological Centre Odesa 65055 Ukraine Details
Zaporizhzhya Regional Clinical Oncology Center Zaporizhzhya 69040 Ukraine Details
Leeds Teaching Hospital NHS Trust. St. James University Hospital Leeds LS9 7TF United Kingdom Details
*Shaded cells indicate that there was no data available from for the field