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| NCT ID | NCT03336333 |
| Title | A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL (SEQUOIA) |
| Acronym | SEQUOIA |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | BeiGene |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NZL | ITA | GBR | FRA | ESP | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Georgetown University Medical Center | Washington | District of Columbia | 20007 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| Augusta University | Augusta | Georgia | 30912 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60208 | United States | Details | |
| Montgomery Cancer Center | Mount Sterling | Kentucky | 40353 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Research Medical Center - Kansas City | Kansas City | Missouri | 64132 | United States | Details | |
| Washington University | Saint Louis | Missouri | 63110 | United States | Details | |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89014 | United States | Details | |
| Summit Medical Group, PA | Florham Park | New Jersey | 07932 | United States | Details | |
| Mount Sinai | New York | New York | 10029 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| University of Rochester | Rochester | New York | 14642 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27705 | United States | Details | |
| Oregon Health & Science University | Portland | Oregon | 97239 | United States | Details | |
| Prairie Lakes Healthcare System | Watertown | South Dakota | 57201 | United States | Details | |
| Tennessee Oncology - Centennial Clinic | Nashville | Tennessee | 37203 | United States | Details | |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | United States | Details | |
| Texas Oncology - Tyler | Tyler | Texas | 75702 | United States | Details | |
| University of Virginia | Charlottesville | Virginia | 22908 | United States | Details | |
| VA Puget Sound Health Care System, Pathology and Laboratory Medicine Services 113 | Seattle | Washington | 98108 | United States | Details | |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | United States | Details | |
| Concord Hospital | Concord | New South Wales | 2139 | Australia | Details | |
| The Tweed Hospital | Tweed Heads | New South Wales | Australia | Details | ||
| Calvary Mater Newcastle Hospital | Waratah | New South Wales | Australia | Details | ||
| Westmead Hospital | Westmead | New South Wales | Australia | Details | ||
| Icon Cancer Care - Wesley | Auchenflower | Queensland | Australia | Details | ||
| Royal Brisbane and Women's Hospital | Herston | Queensland | Australia | Details | ||
| Princess Alexandra Hospital | Woolloongabba | Queensland | Australia | Details | ||
| Royal Adelaide Hospital | Adelaide | South Australia | Australia | Details | ||
| The Queen Elizabeth Hospital | Woodville South | South Australia | Australia | Details | ||
| Royal Hobart Hospital | Hobart | Tasmania | Australia | Details | ||
| Monash Medical Centre | Bentleigh East | Victoria | Australia | Details | ||
| Box Hill Hospital | Box Hill | Victoria | Australia | Details | ||
| Peter MacCallum Cancer Centre | East Melbourne | Victoria | Australia | Details | ||
| Saint Vincent's Hospital Melbourne | Fitzroy | Victoria | Australia | Details | ||
| Peninsula Private Hospital | Frankston | Victoria | Australia | Details | ||
| Royal Perth Hospital | Perth | Western Australia | Australia | Details | ||
| Icon Cancer Care - South Brisbane | South Brisbane | Australia | Details | |||
| Medizinische Universitätsklinik Innsbruck | Innsbruck | Austria | Details | |||
| Allgemeines Krankenhaus der Stadt Linz | Linz | Austria | Details | |||
| Krankenhaus der Barmherzigen Schwestern Linz | Linz | Austria | Details | |||
| Universitätsklinik für Innere Medizin Salzburg | Salzburg | Austria | Details | |||
| Klinikum Wels-Grieskirchen | Wels | Austria | Details | |||
| GasthuisZusters Antwerpen Sint-Augustinus | Wilrijk | Antwerpen | Belgium | Details | ||
| Centre Hospitalier Universitaire Universite Catholique de Louvain Site Godinne | Yvoir | Namur | Belgium | Details | ||
| Cliniques du Sud-Luxembourg Site Clinique Saint-Joseph | Arlon | Belgium | Details | |||
| Universitair Ziekenhuis Brussel | Brussels | Belgium | Details | |||
| Universitair Ziekenhuis Gent | Gent | Belgium | Details | |||
| Centre Hospitalier Universitaire (CHU) de Liège - Site du Sart Tilman | Liège | Belgium | Details | |||
| Clinique Saint-Pierre | Ottignies | Belgium | Details | |||
| Anhui Provincial Hospital | Hefei | Anhui | 230000 | China | Details | |
| Peking University Third Hospital | Beijing | Beijing | 100000 | China | Details | |
| Beijing Friendship Hospital, Capital Medical University | Beijing | Beijing | 100050 | China | Details | |
| Peking Union Medical College Hospital | Beijing | Beijing | 100730 | China | Details | |
| Xinqiao Hospital | Chongqing | Chongqing | 400037 | China | Details | |
| Fujian Medical University Union Hospital | Fuzhou | Fujian | 350001 | China | Details | |
| Quanzhou First Affiliated Hospital of Fujian Medical University | Quanzhou | Fujian | 362000 | China | Details | |
| Guangdong Provincial People's Hospital | Guangzhou | Guangdong | 510080 | China | Details | |
| Henan Cancer Hospital | Zhengzhou | Henan | 450000 | China | Details | |
| Union Hospital of Tongji Medical College, Huazhong University of Science and Technology | Wuhan | Hubei | 430022 | China | Details | |
| Jiangsu Province Hospital | Nanjing | Jiangsu | 290029 | China | Details | |
| The First Affiliated Hospital of Soochow University Branch Shizi | Suzhou | Jiangsu | 215006 | China | Details | |
| Wuxi People's Hospital | Wuxi | Jiangsu | 214023 | China | Details | |
| The First Affiliated Hospital of Nanchang University Branch Donghu | Nanchang | Jiangxi | 330006 | China | Details | |
| The First Hospital of Jilin University | Changchun | Jilin | 130021 | China | Details | |
| West China Hospital, Sichuan University | Chengdu | Sichuan | 610041 | China | Details | |
| Institute of Hematology and Hospital of Blood Disease | Tianjin | Tianjin | 300020 | China | Details | |
| Tianjin Medical University Cancer Institute and Hospital | Tianjin | Tianjin | 300060 | China | Details | |
| The First Affiliated Hospital, Zhejiang University School of Medicine | Hangzhou | Zhejiang | 310003 | China | Details | |
| Fakultní Nemocnice Brno | Brno | Czechia | Details | |||
| Fakultní Nemocnice Hradec Králové - Ústav Klinické Imunologie a Alergologie | Hradec Králové | Czechia | Details | |||
| Fakultní Nemocnice Olomouc | Olomouc | Czechia | Details | |||
| Fakultní Nemocnice Ostrava | Ostrava-Poruba | Czechia | Details | |||
| Všeobecná Fakultní Nemocnice v Praze | Praha | Czechia | Details | |||
| Centre Hospitalier Universitaire de Poitier- Hopital de la Miletrie - Hopital Jean Bernard | Poitiers Cedex | Poitou-charentes | France | Details | ||
| Centre Hospitalier Victor Dupouy d'Argenteuil | Argenteuil | France | Details | |||
| Institut Bergonié | Bordeaux | France | Details | |||
| CHU de Caen Côte de Nacre | Caen | France | Details | |||
| Centre Hospitalier Départemental Vendée | La Roche sur Yon | France | Details | |||
| Centre Hospitalier Le Mans | Le Mans | France | Details | |||
| Centre Hospitalier Universitaire Limoges CHU de Limoges | Limoges | France | Details | |||
| Centre Léon Bérard | Lyon | France | Details | |||
| Institut Paoli Calmettes | Marseille | France | Details | |||
| Centre Hospitalier Universitaire Nantes - Hotel Dieu | Nantes | France | Details | |||
| Groupe Hospitalier Pitie-Salpetriere | Paris | France | Details | |||
| Groupe Hospitalier du Haut Leveque | Pessac | France | Details | |||
| Centre hospitalier Lyon Sud | Pierre-Bénite | France | Details | |||
| Hôpital Robert Debré | Reims | France | Details | |||
| Hôpital Pontchaillou | Rennes | France | Details | |||
| Centre Henri-Becquerel | Rouen | France | Details | |||
| Centre Hospitalier Régional et Universitaire de Tours Hôpital Bretonneau | Tours | France | Details | |||
| Centre Hospitalier Universitaire de Nancy - Hôpital de Brabois | Vandoeuvre-lès-Nancy | France | Details | |||
| Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | Brescia | Italy | Details | |||
| Presidio Ospedale di Montichiari | Brescia | Italy | Details | |||
| Presidio Ospedaliero di Gardone Val Trompia | Brescia | Italy | Details | |||
| Azienda Ospedaliera Universitaria San Martino | Genova | Italy | Details | |||
| Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori | Meldola | Italy | Details | |||
| Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda | Milano | Italy | Details | |||
| Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico | Milano | Italy | Details | |||
| Ospedale San Raffaele | Milano | Italy | Details | |||
| Universita Degli Studi di Modena-Azienda Ospedaliere Policlinco | Modena | Italy | Details | |||
| Azienda Unita Sanitaria Locale di Ravenna | Ravenna | Italy | Details | |||
| Fondazione Policlinico Universitario Agostino Gemelli | Roma | Italy | Details | |||
| Universita degli Studi di Roma "La Sapienza" - Umberto I Policlinico di Roma | Roma | Italy | Details | |||
| Ospedale Casa Sollievo della Sofferenza | San Giovanni Rotondo | Italy | Details | |||
| Azienda Ospedaliera Santa Maria di Terni | Terni | Italy | Details | |||
| Azienda Ospedaliera Città della Salute e della Scienza di Torino | Torino | Italy | Details | |||
| North Shore Hospital | North Shore | Auckland | New Zealand | Details | ||
| Auckland City Hospital | Grafton | Aukland | New Zealand | Details | ||
| Palmerston North Hospital | Palmerston North | Manawatu-wanganui | New Zealand | Details | ||
| Christchurch Hospital | Christchurch | New Zealand | Details | |||
| Tauranga Hospital | Tauranga | New Zealand | Details | |||
| Wojewódzki Szpital Specjalistyczny w Legnicy | Legnica | Dolnoslaskie | Poland | Details | ||
| Szpital Specjalistyczny w Brzozowie Podkarpacki Ośrodek Onkologiczny im. Ks. B. Markiewicza | Brzozów | Poland | Details | |||
| Samodzielny Publiczny Zakład Opieki Zdrowotnej Zespół Szpitali Miejskich | Chorzów | Poland | Details | |||
| Copernicus Podmiot Leczniczy Wojewódzkiego Centrum Onkologii | Gdańsk | Poland | Details | |||
| Szpitale Pomorskie Spółka z ograniczoną odpowiedzialnością | Gdynia | Poland | Details | |||
| Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach | Gliwice | Poland | Details | |||
| Malopolskie Centrum Medyczne | Kraków | Poland | Details | |||
| Centrum Onkologii Ziemi Lubelskiej | Lublin | Poland | Details | |||
| Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi | Łódź | Poland | Details | |||
| Sverdlovsk Regional Clinical Hospital #1 | Ekaterinburg | Russian Federation | Details | |||
| Kaluga Regional Hospital | Kaluga | Russian Federation | Details | |||
| Clinical Oncology Dispensary, Kazan | Kazan | Russian Federation | Details | |||
| Kemerovo Regional Clinical Hospital n.a. S.V. Belyaev | Kemerovo | Russian Federation | Details | |||
| City Clinical Hospital No. 52 of the Moscow Healthcare Department | Moscow | Russian Federation | Details | |||
| N. N. Blokhin Russian Cancer Research Center | Moscow | Russian Federation | Details | |||
| Nizhniy Novgorod Regional Clinical Hospital N.A. | Nizhny Novgorod | Russian Federation | Details | |||
| Penza Regional Oncology Dispensary | Penza | Russian Federation | Details | |||
| Municipal Healthcare Institution "Clinical Medical Sanitary Establishment #1" | Perm | Russian Federation | Details | |||
| Ryazan Regional Clinical Hospital | Ryazan | Russian Federation | Details | |||
| FGU Russian Scientific Research Institute of Hematology and Transfusiology | Saint Petersburg | Russian Federation | Details | |||
| State Healthcare Institution Oncologic Dispensary No. 2 - Health Department of Krasnodar Region | Sochi | Russian Federation | Details | |||
| Tula Area Clinical Hospital | Tula | Russian Federation | Details | |||
| State Budgetary Healthcare Institution "Volgograd Regional Clinical Oncology Dispensary #1" | Volgograd | Russian Federation | Details | |||
| Central City Hospital # 7 | Yekaterinburg | Russian Federation | Details | |||
| Institut Català d'Oncologia | Badalona | Barcelona | Spain | Details | ||
| Hospital Universitari Parc Taulí | Sabadell | Barcelona | Spain | Details | ||
| Hospital del Mar | Barcelona | Spain | Details | |||
| Hospital Universitario Vall d'Hebron | Barcelona | Spain | Details | |||
| Institut Català d'Oncologia - L'Hospitalet de Llobregat | Barcelona | Spain | Details | |||
| Clinica Universidad de Navarra Madrid | Madrid | Spain | Details | |||
| Hospital Universitario de La Princesa | Madrid | Spain | Details | |||
| Hospital Universitario Ramón Y Cajal | Madrid | Spain | Details | |||
| MD Anderson Cancer Center - Madrid | Madrid | Spain | Details | |||
| Hospital Universitario Puerta de Hierro - Majadahonda | Majadahonda | Spain | Details | |||
| Clínica Universidad de Navarra Pamplona | Pamplona | Spain | Details | |||
| Hospital Universitario La Fe | Valencia | Spain | Details | |||
| Hospital de Día Quirónsalud Zaragoza | Zaragoza | Spain | Details | |||
| Skånes Universitetssjukhus i Lund | Lund | Skane | Sweden | Details | ||
| Södra Älvsborgs Sjukhus - Borås | Borås | Vastra Gotaland | Sweden | Details | ||
| Sahlgrenska Universitetssjukhuset, Östra sjukhuset | Göteborg | Vastra Gotaland | Sweden | Details | ||
| Sunderby Sjukhus | Lulea | Sweden | Details | |||
| Universitetssjukhuset Örebro | Orebro | Sweden | Details | |||
| Karolinska Universitetssjukhuset - Solna | Stockholm | Sweden | Details | |||
| Uppsala Akademiska Sjukhus | Uppsala | Sweden | Details | |||
| Hualien Tzu Chi Hospital | Hualien City | Taiwan | Details | |||
| Taipei Medical University - Shuang Ho Hospital | New Taipei City | Taiwan | Details | |||
| Chi Mei Hospital Liouying | Tainan City | Taiwan | Details | |||
| National Taiwan University Hospital | Taipei | Taiwan | Details | |||
| Heart of England NHS Foundation Trust | Birmingham | England | United Kingdom | Details | ||
| Cambridge University Hospitals NHS Foundation Trust | Cambridge | England | United Kingdom | Details | ||
| East Kent Hospitals University NHS Foundation Trust | Canterbury | England | United Kingdom | Details | ||
| Sarah Cannon Research Institute London | London | England | United Kingdom | Details | ||
| Maidstone and Tunbridge Wells NHS Trust | Maidstone | England | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | England | United Kingdom | Details | ||
| The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust | Bournemouth | United Kingdom | Details | |||
| The Leeds Teaching Hospitals NHS Trust | Leeds | United Kingdom | Details | |||
| Barts and The London NHS Trust | London | United Kingdom | Details | |||
| The Royal Marsden NHS Foundation Trust | London | United Kingdom | Details | |||
| Norfolk and Norwich University Hospital | Norwich | United Kingdom | Details | |||
| Nottingham University Hospitals NHS Trust | Nottingham | United Kingdom | Details | |||
| Derriford Hospital | Plymouth | United Kingdom | Details | |||
| Southampton General Hospital | Southampton | United Kingdom | Details | |||
| City Hospitals Sunderland NHS Foundation Trust | Sunderland | United Kingdom | Details | |||
| The Royal Marsden NHS Foundation Trust | Sutton | United Kingdom | Details | |||
| The Royal Wolverhampton NHS Trust | Wolverhampton | United Kingdom | Details |