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NCT ID NCT03337724
Title A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer (IPATunity130)
Recruitment Active, not recruiting
Gender both
Phase Phase II
Variant Requirements Yes
Sponsors Hoffmann-La Roche
Indications

Her2-receptor negative breast cancer

triple-receptor negative breast cancer

Therapies

Ipatasertib + Paclitaxel

Paclitaxel

Age Groups: adult | senior
Covered Countries USA | ITA | FRA | ESP | DEU | CAN | BEL

Facility Status City State Zip Country Details
UCSD Moores Cancer Center La Jolla California 92093 United States Details
USC Norris Cancer Center Los Angeles California 90033 United States Details
USC Norris Cancer Center; USC Oncology Hematology Newport Beach Newport Beach California 92663 United States Details
Kaiser Permanente - Oakland Oakland California 94611 United States Details
Kaiser Permanente - Roseville Roseville California 95661 United States Details
Kaiser Permanente Sacramento Medical Center Sacramento California 95814 United States Details
UC Davis; Comprehensive Cancer Center Sacramento California 95817 United States Details
Kaiser Permanente - San Francisco (2238 Geary) San Francisco California 94115 United States Details
UCSF Comprehensive Cancer Ctr San Francisco California 94158 United States Details
K. Permanente - San Jose San Jose California 95119 United States Details
Kaiser Permanente - San Leandro San Leandro California 94577 United States Details
K. Permanente - Santa Clara Santa Clara California 95051 United States Details
Kaiser Permanente - South San Francisco South San Francisco California 94080 United States Details
Kaiser Permanente - Vallejo Vallejo California 94589 United States Details
K. Permanente - Walnut Creek Walnut Creek California 94596 United States Details
Memorial Regional Hospital Hollywood Florida 33021 United States Details
Mount Sinai Comprehensive Cancer Center Miami Beach Florida 33140 United States Details
UF Health Cancer Center at Orlando Health Orlando Florida 32824 United States Details
Memorial Hospital West Pembroke Pines Florida 33028 United States Details
University of Maryland Baltimore Maryland 21201 United States Details
Mercy Medical Center Baltimore Maryland 21202 United States Details
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center Baltimore Maryland 21287 United States Details
Memorial Sloan Kettering Cancer Center at Westchester Harrison New York 10604 United States Details
Memorial Sloan Kettering New York New York 10065 United States Details
West Clinic Germantown Tennessee 38138 United States Details
Texas Oncology, P.A. Dallas Texas 75246 United States Details
UT Southwestern Medical Center; Simmons Comprehensive Cancer Center, Simmons Pharmacy Dallas Texas 75390 United States Details
Oncology Consultants PA Houston Texas 77030 United States Details
Fundación CENIT para la Investigación en Neurociencias Buenos Aires C1125ABD Argentina Details
Hosp Provincial D. Centenarios; Oncology Dept Rosario S2002KDS Argentina Details
Chris O'Brien Lifehouse Camperdown New South Wales 2050 Australia Details
Calvary Mater Newcastle; Medical Oncology Waratah New South Wales 2298 Australia Details
Westmead Hospital; Medical Oncology Wentworthville New South Wales 2145 Australia Details
Mater Hospital; Cancer Services South Brisbane Queensland 4101 Australia Details
Cabrini Medical Centre; Oncology Malvern Victoria 3144 Australia Details
Fiona Stanley Hospital; FSH Cancer Centre Clinical Trials Unit Bull Creek Western Australia 6149 Australia Details
Cliniques Universitaires St-Luc Bruxelles 1200 Belgium Details
GHdC Site Notre Dame Charleroi 6000 Belgium Details
UZ Leuven Gasthuisberg Leuven 3000 Belgium Details
Santa Casa de Misericordia de Salvador Salvador BA 40050-410 Brazil Details
Hospital Araujo Jorge; Departamento de Ginecologia E Mama Goiania GO 74605-070 Brazil Details
Hospital do Câncer de Londrina Londrina PR 86015-520 Brazil Details
Instituto Nacional de Cancer - INCa; Oncologia Rio de Janeiro RJ 20560-120 Brazil Details
Hospital Sao Lucas - PUCRS Porto Alegre RS 90610-000 Brazil Details
Hospital Nossa Senhora da Conceicao Porto Alegre RS 91350-200 Brazil Details
Faculdade de Medicina do ABC - FMABC Santo Andre SP 09060-650 Brazil Details
Hospital Perola Byington Sao Paulo SP 01317-000 Brazil Details
British Columbia Cancer Agency (Bcca) - Vancouver Cancer Centre Vancouver British Columbia V5Z 4E6 Canada Details
Jewish General Hospital Montreal Quebec H3T 1E2 Canada Details
Sociedad de Investigaciones Medicas Ltda (SIM) Temuco 4810469 Chile Details
Clinica CIMCA San José 10103 Costa Rica Details
ICIMED Instituto de Investigación en Ciencias Médicas San José 10108 Costa Rica Details
Masarykův onkologický ústav; Klinika komplexní onkologické péče Brno 656 53 Czechia Details
Fakultni nemocnice Olomouc; Onkologicka klinika Olomouc 779 00 Czechia Details
CHU Besançon - Hôpital Jean Minjoz Besançon Cedex 25030 France Details
Polyclinique Bordeaux Nord Aquitaine Bordeaux 33300 France Details
Centre Georges Francois Leclerc; Oncologie 3 Dijon 21079 France Details
ICM; Medecine B3 Montpellier cedex 5 34298 France Details
Centre Catherine De Sienne Nantes 44202 France Details
APHP - Hospital Saint Louis Paris 75475 France Details
Institut Jean Godinot; Oncologie Medicale Reims CEDEX 51056 France Details
Onkologische Schwerpunktpraxis Kurfürstendamm Berlin 10707 Germany Details
Praxis für Interdisziplinäre Onkologie und Hämatologie GbR Freiburg 79110 Germany Details
Universitätsklinikum Hamburg-Eppendorf; Frauenklinik Hamburg 20246 Germany Details
Universitätsklinikum des Saarlandes; Klinik f. Frauenheilkunden und Geburtshilfe Homburg/Saar 66424 Germany Details
Praxis Dr.med. Katja Ziegler-Löhr Köln 50679 Germany Details
Dres. Andreas Köhler und Roswitha Fuchs Langen 63225 Germany Details
Mühlenkreiskliniken; Johannes Wesling Klinikum Minden; Klinik für Frauenheilkunde und Geburtshilfe Minden 32429 Germany Details
Oncologianova GmbH - Gesellschaft für Innovationen in der Onkologie Recklinghausen 45659 Germany Details
Universitätsfrauen- und Poliklinik am Klinikum Suedstadt Rostock 18059 Germany Details
Universitätsklinikum Würzburg; Frauenklinik Würzburg 97080 Germany Details
Anticancer Hospital Ag Savas; 1St Dept of Internal Medicine Athens 115 22 Greece Details
Agioi Anargyroi; 3Rd Dept. of Medical Oncology Athens 145 64 Greece Details
Euromedical General Clinic of Thessaloniki; Oncology Department Thessaloniki 546450 Greece Details
Orszagos Onkologial Intezet; Onkologiai Osztaly X Budapest 1122 Hungary Details
Borsod-Abauj-Zemplen Megyei Korhaz Es Egyetemi Oktato Korhaz; Onkologiai Osztaly Miskolc 3501 Hungary Details
Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika Szeged 6720 Hungary Details
Hetenyi Geza County Hospital; Onkologiai Kozpont Szolnok 5004 Hungary Details
Zala County Hospital ICU Zalaegerszeg 8900 Hungary Details
Indraprastha Apollo Hospitals New Delhi Delhi 110076 India Details
Rajiv Gandhi Cancer Inst.&Research Center; Medical Oncology New Delhi Delhi 110085 India Details
Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica Napoli Campania 80131 Italy Details
Azienda Ospedaliero-Universitaria S.Orsola-Malpighi; Unità Operativa Oncologia Medica Bologna Emilia-Romagna 40138 Italy Details
Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica Aviano Friuli-Venezia Giulia 33081 Italy Details
Ospedale Santa Maria Annunziata; Oncologia Bagno a Ripoli Toscana 50012 Italy Details
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II Padova Veneto 35128 Italy Details
Aichi Cancer Center Hospital Aichi 464-8681 Japan Details
National Cancer Center Hospital East Chiba 277-8577 Japan Details
National Hospital Organization Kyushu Cancer Center;Breast Oncology Fukuoka 811-1395 Japan Details
Fukushima Medical University Hospital Fukushima 960-1295 Japan Details
Hyogo College of Medicine Hospital Hyogo 663-8501 Japan Details
St. Marianna University Hospital Kanagawa 216-8511 Japan Details
Kanagawa Cancer Center Kanagawa 241-8515 Japan Details
Tokai University Hospital Kanagawa 259-1193 Japan Details
Kumamoto Shinto General Hospital Kumamoto 862-8655 Japan Details
Niigata Cancer Center Hospital Niigata 951-8566 Japan Details
Okayama University Hospital Okayama 700-8558 Japan Details
National Hospital Organization Osaka National Hospital Osaka 540-0006 Japan Details
Kinki University Hospital, Faculty of Medicine; Surgery Osaka 589-8511 Japan Details
Saitama Cancer Center, Breast Oncology Saitama 362-0806 Japan Details
Shizuoka Cancer Center Shizuoka 411-8777 Japan Details
National Cancer Center Hospital Tokyo 104-0045 Japan Details
St. Luke's International Hospital Tokyo 104-8560 Japan Details
The Cancer Institute Hospital of JFCR Tokyo 135-8550 Japan Details
Showa University Hospital; Breast Surgery Tokyo 142-8666 Japan Details
National Cancer Center Goyang-si 10408 Korea, Republic of Details
Inha University Hospital Incheon 22332 Korea, Republic of Details
Seoul National University Bundang Hospital Seongnam-si 13605 Korea, Republic of Details
Seoul National University Hospital Seoul 03080 Korea, Republic of Details
Severance Hospital, Yonsei University Health System Seoul 03722 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
Samsung Medical Center Seoul 06351 Korea, Republic of Details
Centro Medico Dalinde Cdmx Mexico CITY (federal District) 06760 Mexico Details
Centro Médico Zambrano Hellion Monterrey Nuevo LEON 66278 Mexico Details
Merida | Investigacion Clinica Mérida Yucatan 97125 Mexico Details
Consultorio de Medicina Especializada; Dentro de Condominio San Francisco Mexico City 03100 Mexico Details
Clinical Hospital; Oncology Department Bitola 7000 North Macedonia Details
PHI University Clinic of Radiotherapy and Oncology; Breast malignancy Skopje 1000 North Macedonia Details
PHI University Clinic of Radiotherapy and Oncology; Malignant diseases of thorax Skopje 1000 North Macedonia Details
Centro Medico Monte Carmelo Arequipa 04001 Peru Details
Hospital Daniel Alcides Carrion Callao 07021 Peru Details
Clínica San Gabriel; Unidad de Investigación Oncológica de la Clínica San Gabriel Lima 15088 Peru Details
Hospital Nacional Cayetano Heredia; Ocología; Servicio de Hematología Oncología Médica Lima 15102 Peru Details
Oncosalud Sac; Oncología Lima 41 Peru Details
Instituto Nacional de Enfermedades Neoplasicas Lima Lima 34 Peru Details
Clinica Ricardo Palma San Isidro Lima 27 Peru Details
Instituto Regional de Enfermedades Neoplasicas - IREN Norte Trujillo 13014 Peru Details
Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; III Klin. Radioter. i Chemioter. Gliwice 44-101 Poland Details
Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie; Klinika Nowotworow Piersi i Chirurgii Rekonstr Warszawa 02-781 Poland Details
Instyt. Centrum Zdrowia Matki Polki; Klinika Chirurgii Onk. Chorób Piersi z Podod. Onko Klinicznej Łódź 93-338 Poland Details
Arkhangelsk Regional Clinical Oncology Dispensary Arkhangelsk Arhangelsk 163045 Russian Federation Details
Moscow City Oncology Hospital #62 Moscovskaya Oblast Moskovskaja Oblast 143423 Russian Federation Details
Blokhin Cancer Research Center; Combined Treatment Moskva Moskovskaja Oblast 115478 Russian Federation Details
Ivanovo Regional Oncology Dispensary Ivanovo 153040 Russian Federation Details
SBIH Kaluga Region Clinical Oncology Dispensary Kaluga 248007 Russian Federation Details
Clinical Oncology Dispensary of Ministry of Health of Tatarstan Kazan 420029 Russian Federation Details
Federal State Institution, Moscow Research Oncology Institute n.a. P.A. Hertzen; Oncourology Moscow 125284 Russian Federation Details
FSI Rostov research oncological institute of MoH and SD of RF; PAD Rostov-on-Don 344037 Russian Federation Details
S-Pb clinical scientific practical center of specialized kinds of medical care (oncological) Saint-Petersburg 197758 Russian Federation Details
National University Hospital; National University Cancer Institute, Singapore (NCIS) Singapore 119228 Singapore Details
National Cancer Centre; Medical Oncology Singapore 169610 Singapore Details
Institute of Oncology Ljubljana Ljubljana 1000 Slovenia Details
Medical Oncology Centre of Rosebank; Oncology Johannesburg 2196 South Africa Details
Hospital Provincial de Castellon; Servicio de Oncologia Castellon de La Plana Castellon 12002 Spain Details
Hospital Universitario Reina Sofia; Servicio de Oncologia Córdoba Cordoba 14004 Spain Details
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia Santiago de Compostela LA Coruña 15706 Spain Details
Hospital Universitario Puerta de Hierro; Servicio de Oncologia Majadahonda Madrid 28222 Spain Details
Hospital del Mar; Servicio de Oncologia Barcelona 08003 Spain Details
Vall d´Hebron Institute of Oncology (VHIO), Barcelona Barcelona 08035 Spain Details
Hospital Clinic Barcelona; Servicio de oncologia Barcelona 08036 Spain Details
Hospital de Donostia; Servicio de Oncologia Guipuzcoa 20014 Spain Details
Hospital Ramon y Cajal; Servicio de Oncologia Madrid 28034 Spain Details
HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia Madrid 28050 Spain Details
Hospital Universitario Virgen del Rocio; Servicio de Oncologia Sevilla 41013 Spain Details
Hospital Clinico Universitario; Oncologia Valencia 46010 Spain Details
Chi Mei Medical Center Liou Ying Campus Liuying Township 736 Taiwan Details
Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology Taipei City 11259 Taiwan Details
VETERANS GENERAL HOSPITAL; Department of General Surgery Taipei 00112 Taiwan Details
National Taiwan Uni Hospital; General Surgery Taipei 100 Taiwan Details
Ankara City Hospital Ankara 06490 Turkey Details
Dicle Uni Medical Faculty; Internal Medicine Diyarbakir 10000 Turkey Details
Medipol University MF; Oncology Department Istanbul 34214 Turkey Details
Prof. Dr. Cemil Tascioglu City Hospital; Med Onc Istanbul 34384 Turkey Details
Katip Celebi University Ataturk Training and Research Hospital; Oncology Izmir 35360 Turkey Details
Sakarya University Medical School; Medical Oncology Sakarya 54100 Turkey Details
Chemotherapy SI Dnipropetrovsk MA of MOHU Dnipropetrovsk 49102 Ukraine Details
Kyiv City Clinical Oncological Center, Day Hospital Department for Oncological patients Kiev 03115 Ukraine Details
National Cancer Institute MOH of Ukraine Kiev 36022 Ukraine Details
Lviv State Oncological Regional Treatment and Diagnostic Center Lviv 79031 Ukraine Details
Velindre Cancer Centre Cardiff CF14 2TL United Kingdom Details
University Hospital coventry; Oncology Department Coventry CV2 2DX United Kingdom Details
The Beatson West of Scotland Cancer Centre; Cancer Clinical Trials Unit Glasgow G12 0YN United Kingdom Details
Royal Marsden Hospital - London London SW3 6JJ United Kingdom Details
Derriford Hospital Plymouth PL6 8DH United Kingdom Details
Royal Stoke University Hospital Stoke-on-Trent ST4 6QG United Kingdom Details
Royal Marsden Hospital; Dept of Medical Oncology Sutton SM2 5PT United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field