Clinical Trial Detail


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NCT ID NCT03358472
Title Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Incyte Corporation

head and neck squamous cell carcinoma



Carboplatin + Fluorouracil

Epacadostat + Pembrolizumab

Cetuximab + Cisplatin

Age Groups: adult | senior
Covered Countries USA | ITA | ESP | CAN | AUT

Facility Status City State Zip Country Details
Pacific Cancer Medical Center Anaheim California 19026 United States Details
UC Davis Comprehensive Cancer Center Sacramento California 95817 United States Details
St. Joseph Heritage Healthcare Santa Rosa California 95403 United States Details
University of Colorado Cancer Center Aurora Colorado 80045 United States Details
Yale Cancer Center New Haven Connecticut 06520 United States Details
Northwest Georgia Oncology Centers PC Douglasville Georgia 30134 United States Details
U of Kansas Cancer Center Westwood Kansas 66205 United States Details
Baptist Health Louisville Kentucky 40223 United States Details
St. Vincent Healthcare Cancer Ctr Billings Montana 59102 United States Details
New Mexico Cancer Care Alliance Albuquerque New Mexico 87106 United States Details
Oklahoma Cancer Specialists and Research Tulsa Oklahoma 74146 United States Details
Providence Portland Med Center Portland Oregon 97213 United States Details
Huntsman Cancer Institute Univ of Utah Salt Lake City Utah 19026 United States Details
Viginia Mason Med Ctr Seattle Washington 98101 United States Details
Chris OBrien Lifehouse Camperdown New South Wales 2050 Australia Details
Macquarie University Hospital North Ryde New South Wales 2109 Australia Details
Royal Brisbane & Women s Hospital Herston Queensland 4029 Australia Details
Landeskrankenhaus Salzburg Salzburg 5020 Austria Details
Allgemeines Krankenhaus der Stadt Wien Wien 1090 Austria Details
Juravinski Cancer Center Hamilton Health Sciences Hamilton Ontario L8V 5C2 Canada Details
Princess Margaret Cancer Centre Toronto Ontario M5G 2M9 Canada Details
Jewish General Hospital Montreal Quebec H3T 1E2 Canada Details
CHU de Quebec-Universite Laval-Hotel Dieu de Quebec Quebec G1R 3S1 Canada Details
Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz Miskolc 3526 Hungary Details
Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet Szolnok 5000 Hungary Details
Istituto Europeo di Oncologia Milano 20141 Italy Details
IRRCS Instituto Clinico Humanitas Rozzano 20089 Italy Details
National Cancer Center Hospital East Kashiwa Chiba 277-8577 Japan Details
Kanazawa University Hospital Kanazawa Ishikawa 920-8641 Japan Details
Kanagawa Cancer Center Yokohama Kanagawa 241-8515 Japan Details
Miyagi Cancer Center Natori Miyagi 981-1293 Japan Details
Tohoku University Hospital Sendai Miyagi 980-8574 Japan Details
Hyogo Cancer Center Akashi 673-8558 Japan Details
Kyushu University Hospital Fukuoka 812-8582 Japan Details
Hiroshima University Hospital Hiroshima 734-8551 Japan Details
Hokkaido University Hospital Hokkaido 060-8648 Japan Details
Kobe City Medical Center General Hospital Kobe 650-0047 Japan Details
Kindai University Hospital Osakasayama City 589-8511 Japan Details
Saitama Cancer Center Saitama 362-0806 Japan Details
Shizuoka Cancer Center Hospital and Research Institute Shizuoka 411-8777 Japan Details
The Cancer Institute Hospital of JFCR Tokyo 135-8550 Japan Details
Seoul National University Hospital Seoul 03080 Korea, Republic of Details
Severance Hospital Yonsei University Health System Seoul 03722 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
Mazowiecki Szpital Onkologiczny Wieliszew Mazowieckie 05-135 Poland Details
Przychodnia Lekarska Komed Konin 62-500 Poland Details
Zachodniopomorskie Centrum Onkologii Szczecin 71-730 Poland Details
Inst. Portugues de Oncologia de Coimbra Frencisco Gentil EPE Coimbra 3000-075 Portugal Details
Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE Lisboa 1099-023 Portugal Details
Centro Hospitalar Lisboa Norte EPE - Hospital de Santa Maria Lisboa 1649-035 Portugal Details
Inst. Portugues de Oncologia de Porto Francisco Gentil EPE Porto 4200-072 Portugal Details
Hospital Germans Trias i Pujol. ICO de Badalona Badalona 08916 Spain Details
Hospital General Universitari Vall d Hebron Barcelona 08035 Spain Details
Hospital Ramon y Cajal Madrid 28034 Spain Details
Hospital Universitario 12 de Octubre Madrid 28041 Spain Details
Hospital Infanta Cristina Madrid 28981 Spain Details
Hospital de Nuestra Senora de Valme Sevilla 41014 Spain Details
Hospital Clinico Lozano Blesa Zaragoza 50009 Spain Details
National Cheng Kung University Hospital Tainan 70457 Taiwan Details
National Taiwan University Hospital Taipei 10048 Taiwan Details
Chang Gung Medical Foundation. Linkou Taoyuan 33305 Taiwan Details
Adana Sehir Hastanesi Adana 01370 Turkey Details
Hacettepe Universitesi Tip Fakultesi Hastanesi Ankara 06100 Turkey Details
Trakya Universitesi Tip Fakultesi Edirne 22030 Turkey Details
Istanbul Universitesi Onkoloji Enstitusu Istanbul 34093 Turkey Details
Medipol Hastanesi Istanbul 34214 Turkey Details
Ege Universitesi Tip Fakultesi Hastanesi Izmir 35040 Turkey Details
Inonu Universitesi Turgut Ozal Tip Merkezi Malatya 44280 Turkey Details
North Middlesex Hospital London N18 1QX United Kingdom Details
University College London Hospitals (UCLH) London NW1 2PG United Kingdom Details
The Royal Marsden Foundation Trust London SW3 6JJ United Kingdom Details
The Royal Marsden Nhs Foundation Trust - Chelsea London SW3 6JJ United Kingdom Details
Musgrove Park Hospital Taunton TA1 5DA United Kingdom Details
*Shaded cells indicate that there was no data available from for the field