Clinical Trial Detail


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NCT ID NCT03424005
Title A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic or Inoperable Locally Advanced Triple-Negative Breast Cancer (Morpheus-TNBC) (Morpheus-TNBC)
Recruitment Recruiting
Gender both
Phase Phase Ib/II
Variant Requirements No
Sponsors Hoffmann-La Roche

triple-receptor negative breast cancer


Atezolizumab + Bevacizumab + Selicrelumab

Atezolizumab + RO6874281

Atezolizumab + Bevacizumab

Atezolizumab + Carboplatin + Gemcitabine

Atezolizumab + Eribulin



Atezolizumab + Bevacizumab + Cobimetinib

Atezolizumab + Capecitabine

Atezolizumab + Ipatasertib

Atezolizumab + Ladiratuzumab vedotin

Age Groups: adult | senior
Covered Countries USA

Facility Status City State Zip Country Details
City of Hope Not yet recruiting Duarte California 91010 United States Details
University of California San Diego Medical Center; Moores Cancer Center Recruiting La Jolla California 92093 United States Details
Stanford Cancer Institute Not yet recruiting Stanford California 94305 United States Details
Rocky Mountain Cancer Center - Longmont Recruiting Longmont Colorado 80501 United States Details
H. Lee Moffitt Cancer Center and Research Inst. Recruiting Tampa Florida 33612 United States Details
Hackensack Univ Medical Center; John Theurer Cancer Ctr Completed Hackensack New Jersey 07601 United States Details
Rutgers Cancer Institute of New Jersey Completed New Brunswick New Jersey 08901 United States Details
NYU Langone Medical Center; NYU Perlmutter Cancer Center Completed New York New York 10016 United States Details
Thomas Jefferson University Hospital Recruiting Philadelphia Pennsylvania 19107 United States Details
University of Pittsburgh Medical Center Recruiting Pittsburgh Pennsylvania 15213 United States Details
The West Clinic; West Cancer Center Recruiting Germantown Tennessee 38138 United States Details
Vanderbilt University Medical Center; Vanderbilt University Not yet recruiting Nashville Tennessee 37232 United States Details
Texas Oncology-Plano East Recruiting Plano Texas 75075-7787 United States Details
Peter MacCallum Cancer Centre-East Melbourne Recruiting Melbourne Victoria 3000 Australia Details
Centre Léon Bérard Recruiting Lyon 69008 France Details
Institut régional du Cancer Montpellier Recruiting Montpellier 34298 France Details
Institut Universitaire du Cancer de Toulouse-Oncopole Recruiting Toulouse 31059 France Details
Gustave Roussy Recruiting Villejuif CEDEX 94800 France Details
Universitätsklinikum Erlangen; Frauenklinik Recruiting Erlangen 91054 Germany Details
Universitätsklinikum Essen Recruiting Essen 45147 Germany Details
Hadassah University Medical Center Recruiting Jerusalem Israel Details
Rabin MC; Davidof Center - Oncology Institute Recruiting Petach Tikva 4941492 Israel Details
Sheba Medical Center Recruiting Ramat Gan 5262100 Israel Details
Tel-Aviv Sourasky Medical Center Recruiting Tel Aviv 6423906 Israel Details
Seoul National University Hospital Recruiting Seoul 03080 Korea, Republic of Details
Severance Hospital Recruiting Seoul 03722 Korea, Republic of Details
University of Ulsan College of Medicine - Asan Medical Center Recruiting Seoul 05505 Korea, Republic of Details
Hospital del Mar Recruiting Barcelona 08003 Spain Details
Vall d´Hebron Institute of Oncology (VHIO), Barcelona Recruiting Barcelona 08035 Spain Details
Hospital Universitario Ramon y Cajal Recruiting Madrid 28034 Spain Details
Centro Integral Oncológico Clara Campal Ensayos Clínicos START Recruiting Madrid 28050 Spain Details
Beatson West of Scotland Cancer Centre Recruiting Glasgow G12 0YN United Kingdom Details
Barts Health NHS Trust - St Bartholomew's Hospital Recruiting London EC1A 7BE United Kingdom Details
*Shaded cells indicate that there was no data available from for the field