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NCT ID NCT03589326
Title A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Millennium Pharmaceuticals, Inc.
Indications

acute lymphoblastic leukemia

Therapies

Cytarabine + Methotrexate + Ponatinib

Dexamethasone + Ponatinib + Vincristine Sulfate

Ponatinib + Prednisone + Vincristine Sulfate

Dexamethasone + Imatinib + Vincristine Sulfate

Cytarabine + Imatinib + Methotrexate

Imatinib + Prednisone + Vincristine Sulfate

Age Groups: senior | adult
Covered Countries USA | ITA | FRA | ESP | CAN | AUT

Facility Status City State Zip Country Details
University of Alabama at Birmingham Recruiting Birmingham Alabama 35294 United States Details
City of Hope - Duarte Recruiting Duarte California 91010 United States Details
University of California Los Angeles Recruiting Los Angeles California 90095 United States Details
Augusta University Georgia Cancer Center Recruiting Augusta Georgia 30912 United States Details
Indiana University Recruiting Indianapolis Indiana 46202 United States Details
Indiana Blood & Marrow Transplantation Recruiting Indianapolis Indiana 46237 United States Details
University of Kansas Medical Center Research Institute Recruiting Kansas City Kansas 66160 United States Details
University of Maryland Medical Center Recruiting Baltimore Maryland 21201 United States Details
Hackensack University Medical Center Recruiting Hackensack New Jersey 07601 United States Details
Roswell Park Cancer Institute Recruiting Buffalo New York 14263 United States Details
Monter Cancer Center Recruiting New Hyde Park New York 11042 United States Details
Stony Brook University Medical Center Completed Stony Brook New York 11794 United States Details
Oregon Health and Science University Recruiting Portland Oregon 97239 United States Details
The University of Texas MD Anderson Cancer Center Recruiting Houston Texas 77030 United States Details
Methodist Hospital Recruiting San Antonio Texas 78229 United States Details
Sanatorio Allende Recruiting Cordoba X5000JHQ Argentina Details
Hospital Privado Centro Medico de Cordoba Recruiting Cordoba X5014KEH Argentina Details
Royal North Shore Hospital Recruiting Saint Leonards New South Wales 2065 Australia Details
Box Hill Hospital Recruiting Box Hill Victoria 3128 Australia Details
Monash Medical Centre Recruiting Clayton Victoria 3168 Australia Details
Ordensklinikum Linz Elisabethinen Recruiting Linz Upper Austria 4020 Austria Details
Hanusch Krankenhaus Wiener Gebietskrankenkasse Recruiting Wien Vienna 1140 Austria Details
Universitaetsklinik Fuer Innere Medizin I Recruiting Vienna 1090 Austria Details
Hospital Sao Rafael-Monte Tabor Recruiting Salvador Bahia 41253-190 Brazil Details
Hospital Erasto Gaertner Recruiting Curitiba Parana 81520-060 Brazil Details
Hospital da Cidade Recruiting Passo Fundo RIO Grande DO SUL 99010-260 Brazil Details
Hospital de Clinicas de Porto Alegre Recruiting Porto Alegre RIO Grande DO SUL 90035-003 Brazil Details
Hemocentro Campinas Unicamp Recruiting Campinas SAO Paulo 130383-878 Brazil Details
Fundacao Doutor Amaral Carvalho Recruiting Jau SAO Paulo 17210-120 Brazil Details
Hospital das Clinicas da Faculdade de Medicina da Riberao Preto da Universidade de Sao Paulo Recruiting Ribeirao Preto SAO Paulo 14048-900 Brazil Details
HEMORIO Instituto Estadual de Hematologia Recruiting Rio de Janeiro 20211-030 Brazil Details
Instituto do Cancer do Estado de Sao Paulo Recruiting Sao Paulo 01246-000 Brazil Details
Fundacao Antonio Prudente - A.C.Camargo Cancer Center Recruiting Sao Paulo 01509-900 Brazil Details
University Multiprofile Hospital for Active Treatment Saint Ivan Rilski Recruiting Sofia Sofiya 1431 Bulgaria Details
855 West 12th Avenue Recruiting Vancouver British Columbia V5Z 1M9 Canada Details
The Ottawa Hospital Recruiting Ottawa Ontario K1H 8L6 Canada Details
Hopital Charles-LeMoyne Recruiting Greenfield Park Quebec J4V 2H1 Canada Details
Hopital Maisonneuve-Rosemont Recruiting Montreal Quebec H1T 2M4 Canada Details
Henan Cancer Hospital Recruiting Zhengzhou Henan 450008 China Details
The First Affiliated Hospital of Soochow University/Suzhou First People's Hospital Recruiting Suzhou Jiangsu 215006 China Details
The First Hospital of Jilin University Recruiting Changchun Jilin 130021 China Details
The First Affiliated Hospital, Zhejiang University Recruiting Hangzhou Zhejiang 310003 China Details
Institute of Hematology & Blood Diseases Hospital of CAMS & PUMC Recruiting Tianjin 300041 China Details
Helsingin ja Uudenmaan sairaanhoitopiiri Recruiting Helsinki 00029 HUS Finland Details
Centre Hospitalier de Versailles Hopital Andre Mignot Recruiting Le Chesnay Ile-de-france 78157 France Details
Institut Universitaire du Cancer de Toulouse Oncopole Recruiting Toulouse Cedex 09 Midi-pyrenees 31059 France Details
Center Hospitalier Universitaire d'Angers Recruiting Angers Cedex 9 PAYS DE LA Loire 49933 France Details
Centre Hospitalier Lyon Sud Recruiting Pierre Benite Cedex Rhone-alpes 69495 France Details
Evaggelismos General Hospital Recruiting Athens Attica 10676 Greece Details
University General Hospital of Athens Attikon Recruiting Chaidari Attica 12462 Greece Details
University General Hospital of Patras Panagia I Voithia Recruiting Patra Peloponnese 26504 Greece Details
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Recruiting Meldola Forli-cesena 47014 Italy Details
Azienda Policlinico San Martino Recruiting Genova Liguria 16132 Italy Details
Azienda Ospedaliera San Gerardo di Monza Recruiting Monza Monza E Brianza 20090 Italy Details
Arcispedale Santa Maria Nuova Recruiting Reggio Emilia Reggio Nella Emilia 42123 Italy Details
Ospedale dell'Angelo Recruiting Mestre Venezia 30174 Italy Details
Azienda Ospedaliero Universitaria di Bologna Policlinico Sant'Orsola-Malpighi Recruiting Bologna 40138 Italy Details
Azienda Ospedaliera Vito Fazzi Recruiting Lecce 73100 Italy Details
Istituto Scientifico Universitario San Raffaele Recruiting Milano 20132 Italy Details
Azienda Ospedaliero-Universitaria di Modena Policlinico Recruiting Modena 41124 Italy Details
Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello Recruiting Palermo 90146 Italy Details
Azienda USL della Romagna Recruiting Ravenna 48121 Italy Details
Centro di Ematologia Policlinico Umberto I Universita Sapienza di Roma Recruiting Roma 00161 Italy Details
Fondazione Policlinico Universitario Agostino Gemelli Recruiting Roma 00168 Italy Details
National Cancer Center Hospital East Recruiting Kashiwa-shi Chiba 277-8577 Japan Details
Aiiku Hospital Recruiting Sapporo Hokkaido 064-0804 Japan Details
Tokai University Hospital Recruiting Isehara City Kanagawa 259-1193 Japan Details
Okayama University Hospital Recruiting Okayama-shi Okayama 700-8558 Japan Details
Chiba Aoba Municipal Hospital Recruiting Chiba 260-0852 Japan Details
Fukushima Medical University Hospital Recruiting Fukushima 960-1295 Japan Details
The Catholic University of Korea St. Vincent's Hospital Recruiting Suwon Gyeonggi-do 16247 Korea, Republic of Details
Kyungpook National University Hospital Recruiting Daegu Gyeongsangbuk-do 41944 Korea, Republic of Details
Chonbuk National University Hospital Recruiting Jeonju Jeollabuk-do 54907 Korea, Republic of Details
Inje University Haeundae Paik Hospital Recruiting Busan 48108 Korea, Republic of Details
Yeungnam University Hospital Recruiting Daegu 42415 Korea, Republic of Details
Hospital Universitario Dr. Jose Eleuterio Gonzalez Recruiting Monterrey Nuevo LEON 64460 Mexico Details
Uniwersytecki Szpital Kliniczny we Wroclawiu Recruiting Wroclaw Dolnoslaskie 50-367 Poland Details
Szpital Uniwersytecki w Krakowie Recruiting Krakow Malopolskie 31-501 Poland Details
Uniwersyteckie Centrum Kliniczne Recruiting Gdansk Pomorskie 80-214 Poland Details
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Ministerstwa Spraw Wewnetrznych z Warminsko-Mazurs Recruiting Olsztyn Warminsko-mazurskie 10-228 Poland Details
City Clinical Hospital named after Vikentiy Vikentyevich Veresaev Completed Moscow Moscow CITY 127644 Russian Federation Details
Sverdlovsk Regional Clinical Hospital #1 Active, not recruiting Ekaterinburg Sverdlovsk 620102 Russian Federation Details
National Research Center for Hematology, Dept. of Hematology/Oncology and BMT Active, not recruiting Moscow 125167 Russian Federation Details
Almazov Federal North-West Medical Research Centre of Department of Health of Russian Federation Active, not recruiting Saint Petersburg 197341 Russian Federation Details
Institut Catala d'Oncologia Badalona - Hospital Germans Trias i Pujol Recruiting Badalona Cataluna 08916 Spain Details
Hospital Universitari Vall d'Hebron Recruiting Barcelona 08035 Spain Details
Hospital Universitario de Salamanca Recruiting Salamanca 37007 Spain Details
Hospital Universitari i Politecnic La Fe de Valencia Recruiting Valencia 46026 Spain Details
Hualien Tzu Chi Hospital Recruiting Hualien City Hualien 970 Taiwan Details
China Medical University Hospital Recruiting Taichung Taichung CITY 40447 Taiwan Details
National Cheng Kung University Hospital Recruiting Tainan Tainan CITY 70403 Taiwan Details
Ankara Universitesi Tp Fakultesi Active, not recruiting Ankara 06590 Turkey Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field