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| NCT ID | NCT03653507 |
| Title | A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW) |
| Acronym | GLOW |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Astellas Pharma Global Development, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NLD | GBR | ESP | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Pacific Cancer Care | Monterey | California | 93940 | United States | Details | |
| University of Kansas Cancer Center and Medical Pavilion | Fairway | Kansas | 66205 | United States | Details | |
| Ochsner Clinic CCOP | New Orleans | Louisiana | 70121 | United States | Details | |
| New Mexico Oncology Hematology | Albuquerque | New Mexico | 87109 | United States | Details | |
| Montefiore Medical Center (MMC) | Bronx | New York | 10467 | United States | Details | |
| Weill Cornell Medical College (WCMC) | New York | New York | 10021 | United States | Details | |
| Prisma Health Cancer Institute | Boiling Springs | South Carolina | 29316 | United States | Details | |
| Parkland Hospital | Dallas | Texas | 75390 | United States | Details | |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | United States | Details | |
| Houston Methodist Cancer Center and Institute of Academic Medicine - Oncology | Houston | Texas | 77030 | United States | Details | |
| Utah Cancer Specialist | Salt Lake City | Utah | 84106 | United States | Details | |
| Site AR54009 | Buenos Aires | Argentina | Details | |||
| Site AR54006 | Pergamino | Argentina | Details | |||
| Site AR54001 | San Miguel De Tucuman | Argentina | Details | |||
| Site AR54004 | San Miguel de Tucumán | Argentina | Details | |||
| Site AR54003 | Viedma | Argentina | Details | |||
| Site CA15003 | Chicoutimi | Quebec | Canada | Details | ||
| Site CA15002 | Rimouski | Quebec | Canada | Details | ||
| Site CA15004 | Calgary | Canada | Details | |||
| Site CN86034 | Fuzhou | Fujian | China | Details | ||
| Site CN86037 | Fuzhou | Fujian | China | Details | ||
| Site CN86032 | Haikou | Hainan | China | Details | ||
| Site CN86012 | Zhengzhou | Henan | China | Details | ||
| Site CN86029 | Changsha | Hunan | China | Details | ||
| Site CN86043 | Hengyang | Hunan | China | Details | ||
| Site CN86027 | Suzhou | Jiangsu | China | Details | ||
| Site CN86046 | Wuxi | Jiangsu | China | Details | ||
| Site CN86007 | Hangzhou | Zhejiang | China | Details | ||
| Site CN86044 | Baoding | China | Details | |||
| Site CN86035 | Beijing | China | Details | |||
| Site CN86050 | Beijing | China | Details | |||
| Site CN86025 | Bengbu | China | Details | |||
| Site CN86002 | Changchun | China | Details | |||
| Site CN86049 | Changchun | China | Details | |||
| Site CN86053 | Changchun | China | Details | |||
| Site CN86021 | Changzhou | China | Details | |||
| Site CN86039 | Chengdu | China | Details | |||
| Site CN86052 | Dalian | China | Details | |||
| Site CN86054 | Dalian | China | Details | |||
| Site CN86015 | Fuzhou | China | Details | |||
| Site CN86001 | Guangzhou | China | Details | |||
| Site CN86042 | Guangzhou | China | Details | |||
| Site CN86051 | Haebrin | China | Details | |||
| Site CN86036 | Hangzhou | China | Details | |||
| Site CN86038 | Linyi | China | Details | |||
| Site CN86016 | Nanjing | China | Details | |||
| Site CN86045 | Nanning | China | Details | |||
| Site CN86014 | Shanghai | China | Details | |||
| Site CN86026 | Shantou | China | Details | |||
| Site CN86047 | Shenyang | China | Details | |||
| Site CN86017 | Shijiazhuang | China | Details | |||
| Site CN86009 | Tianjin | China | Details | |||
| Site CN86040 | Tianjin | China | Details | |||
| Site CN86031 | Urumchi | China | Details | |||
| Site CN86004 | Wuhan | China | Details | |||
| Site CN86005 | Wuhan | China | Details | |||
| Site CN86013 | Xi'an | China | Details | |||
| Site CN86030 | Xiamen | China | Details | |||
| Site CN86011 | Xuzhou | China | Details | |||
| Site CN86024 | Zhengzhou | China | Details | |||
| Site HR38501 | Varazdin | Croatia | Details | |||
| Site HR38502 | Zagreb | Croatia | Details | |||
| Site HR38503 | Zagreb | Croatia | Details | |||
| Site GR30001 | Athens | Greece | Details | |||
| Site GR30004 | Heraklion | Greece | Details | |||
| Site GR30003 | Larissa | Greece | Details | |||
| Site GR30005 | Neo Faliro, Piraeus | Greece | Details | |||
| Site GR30007 | Rio Patras | Greece | Details | |||
| Site GR30002 | Thessaloniki | Greece | Details | |||
| Site GR30006 | Thessaloniki | Greece | Details | |||
| Site IE35301 | Dublin | Ireland | Details | |||
| Site IE35302 | Dublin | Ireland | Details | |||
| Site JP81007 | Fukuoka-shi | Fukuoka | Japan | Details | ||
| Site JP81008 | Akashi | Hyogo | Japan | Details | ||
| Site JP81004 | Kita-gun | Kagawa | Japan | Details | ||
| Site JP81003 | Kawasaki | Kanagawa | Japan | Details | ||
| Site JP81001 | Yokohama | Kanagawa | Japan | Details | ||
| Site JP81010 | Suita | Osaka | Japan | Details | ||
| Site JP81005 | Utsunomiya | Tochigi | Japan | Details | ||
| Site JP81002 | Chiba | Japan | Details | |||
| Site JP81006 | Kashiwa | Japan | Details | |||
| Site JP81012 | Koto-ku | Japan | Details | |||
| Site JP81009 | Matsuyama | Japan | Details | |||
| Site JP81011 | Tsukiji | Japan | Details | |||
| Site KR82002 | Daegu | Korea, Republic of | Details | |||
| Site KR82006 | Goyang-si | Korea, Republic of | Details | |||
| Site KR82007 | Gyeonggi-do | Korea, Republic of | Details | |||
| Site KR82014 | Incheon | Korea, Republic of | Details | |||
| Site KR82008 | Jeollanam-do | Korea, Republic of | Details | |||
| Site KR82010 | Jeonju-si | Korea, Republic of | Details | |||
| Site KR82011 | Seongnam-si | Korea, Republic of | Details | |||
| Site KR82001 | Seoul | Korea, Republic of | Details | |||
| Site KR82003 | Seoul | Korea, Republic of | Details | |||
| Site KR82012 | Seoul | Korea, Republic of | Details | |||
| Site KR82013 | Seoul | Korea, Republic of | Details | |||
| Site KR82015 | Seoul | Korea, Republic of | Details | |||
| Site KR82009 | Suwon | Korea, Republic of | Details | |||
| Site MY60001 | Georgetown | Malaysia | Details | |||
| Site MY60004 | Kota Kinabalu | Malaysia | Details | |||
| Site MY60002 | Kuala Lumpur | Malaysia | Details | |||
| Site MY60003 | Kuala Lumpur | Malaysia | Details | |||
| Site MY60005 | Kuala Lumpur | Malaysia | Details | |||
| Site NL31004 | Groningen | Netherlands | Details | |||
| Site NL31003 | Tilburg | Netherlands | Details | |||
| Site PT35109 | Braga | Portugal | Details | |||
| Site PT35110 | Coimbra | Portugal | Details | |||
| Site PT35111 | Guimaraes | Portugal | Details | |||
| Site PT35102 | Lisboa | Portugal | Details | |||
| Site PT35106 | Lisboa | Portugal | Details | |||
| Site PT35105 | Porto | Portugal | Details | |||
| Site PT35108 | Porto | Portugal | Details | |||
| Site PT35104 | Santa Maria da Feira | Portugal | Details | |||
| Site PT35101 | Setubal | Portugal | Details | |||
| Site PT35107 | Vila Real | Portugal | Details | |||
| Site RO40002 | Bucharest | Romania | Details | |||
| Site RO40005 | Cluj-Napoca | Romania | Details | |||
| Site RO40007 | Cluj-Napoca | Romania | Details | |||
| Site RO40003 | Craiova | Romania | Details | |||
| Site RO40004 | Floresti | Romania | Details | |||
| Site RO40001 | Iasi | Romania | Details | |||
| Site RO40006 | Iasi | Romania | Details | |||
| Site RO40008 | Timisoara | Romania | Details | |||
| Site ES34006 | Barcelona | Spain | Details | |||
| Site ES34009 | Barcelona | Spain | Details | |||
| Site ES34010 | Barcelona | Spain | Details | |||
| Site ES34005 | Coruña | Spain | Details | |||
| Site ES34001 | Elche | Spain | Details | |||
| Site ES34002 | Madrid | Spain | Details | |||
| Site ES34003 | Madrid | Spain | Details | |||
| Site ES34008 | Madrid | Spain | Details | |||
| Site ES34013 | Madrid | Spain | Details | |||
| Site ES34011 | Malaga | Spain | Details | |||
| Site ES34004 | Pamplona | Spain | Details | |||
| Site ES34007 | Valencia | Spain | Details | |||
| Site ES34012 | Valencia | Spain | Details | |||
| Site TW88602 | Kaohsiung | Taiwan | Details | |||
| Site TW88603 | Taichung | Taiwan | Details | |||
| Site TW88604 | Taipei | Taiwan | Details | |||
| Site TW88605 | Tianan | Taiwan | Details | |||
| Site TH66002 | Bangkok | Thailand | Details | |||
| Site TH66005 | Bangkok | Thailand | Details | |||
| Site TH66007 | Bangkok | Thailand | Details | |||
| Site TH66009 | Bangkok | Thailand | Details | |||
| Site TH66011 | Laksi | Thailand | Details | |||
| Site TH66001 | Muang | Thailand | Details | |||
| Site TH66003 | Muang | Thailand | Details | |||
| Site TH66006 | Pathumthani | Thailand | Details | |||
| Site TH66010 | Pathumwan | Thailand | Details | |||
| Site TH66004 | Songkla | Thailand | Details | |||
| Site TH66008 | Watthana | Thailand | Details | |||
| Site TR90008 | Pendik | Istanbul | Turkey | Details | ||
| Site TR90003 | Atakum | Turkey | Details | |||
| Site TR90004 | Balcali | Turkey | Details | |||
| Site TR90012 | Bornova | Turkey | Details | |||
| Site TR90001 | Bursa | Turkey | Details | |||
| Site TR90002 | Istanbul | Turkey | Details | |||
| Site TR90010 | Istanbul | Turkey | Details | |||
| Site TR90015 | Istanbul | Turkey | Details | |||
| Site TR90013 | Konyaalti | Turkey | Details | |||
| Site TR90007 | Konya | Turkey | Details | |||
| Site TR90011 | Malatya | Turkey | Details | |||
| Site GB44004 | Cardiff | Wales | United Kingdom | Details | ||
| Site GB44002 | Bristol | United Kingdom | Details | |||
| Site GB44001 | London | United Kingdom | Details | |||
| Site GB44005 | Northwood | United Kingdom | Details |