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NCT ID NCT03755791
Title Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Subjects With Advanced HCC Who Have Not Received Previous Systemic Anticancer Therapy (COSMIC-312)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Exelixis
Indications

hepatocellular carcinoma

Therapies

Cabozantinib

Sorafenib

Atezolizumab + Cabozantinib

Age Groups: senior | adult
Covered Countries USA | ITA | FRA | ESP | DEU | CAN | BEL | AUT

Facility Status City State Zip Country Details
Exelixis Clinical Site #208 Active, not recruiting Phoenix Arizona 85004 United States Details
Exelixis Clinical Site #159 Active, not recruiting Tucson Arizona 85719 United States Details
Exelixis Clinical Site #44 Active, not recruiting La Jolla California 92037 United States Details
Exelixis Clinical Site #112 Active, not recruiting Los Angeles California 90033 United States Details
Exelixis Clinical Site #200 Active, not recruiting Orange California 92868-3201 United States Details
Exelixis Clinical Site #2 Active, not recruiting Rialto California 92377 United States Details
Exelixis Clinical Site #207 Active, not recruiting San Diego California 92093 United States Details
Exelixis Clinical Site #109 Active, not recruiting San Francisco California 94115 United States Details
Exelixis Clinical Site #54 Active, not recruiting San Francisco California 94158 United States Details
Exelixis Clinical Site #58 Active, not recruiting Washington District of Columbia 20007 United States Details
Exelixis Clinical Site #191 Active, not recruiting Miami Florida 33125 United States Details
Exelixis Clinical Site #4 Active, not recruiting Atlanta Georgia 30318 United States Details
Exelixis Clinical Site #195 Active, not recruiting Chicago Illinois 60612 United States Details
Exelixis Clinical Site #120 Active, not recruiting Chicago Illinois 60637 United States Details
Exelixis Clinical Site #6 Active, not recruiting Baltimore Maryland 21202 United States Details
Exelixis Clinical Site #7 Active, not recruiting Burlington Massachusetts 01805 United States Details
Exelixis Clinical Site #11 Active, not recruiting Kansas City Missouri 64128 United States Details
Exelixis Clinical Site #5 Active, not recruiting Kansas City Missouri 64131 United States Details
Exelixis Clinical Site #8 Active, not recruiting Saint Louis Missouri 63110 United States Details
Exelixis Clinical Site #1 Active, not recruiting Las Vegas Nevada 89169 United States Details
Exelixis Clinical Site #14 Active, not recruiting New Brunswick New Jersey 08903 United States Details
Exelixis Clinical Site #76 Active, not recruiting Albuquerque New Mexico 87131 United States Details
Exelixis Clinical Site #12 Active, not recruiting Chapel Hill North Carolina 27599-7600 United States Details
Exelixis Clinical Site #39 Active, not recruiting Toledo Ohio 43614 United States Details
Exelixis Clinical Site #176 Active, not recruiting Portland Oregon 97213 United States Details
Exelixis Clinical Site #88 Active, not recruiting Philadelphia Pennsylvania 19107 United States Details
Exelixis Clinical Site #144 Active, not recruiting Charleston South Carolina 29425 United States Details
Exelixis Clinical Site #199 Active, not recruiting Dallas Texas 75246 United States Details
Exelixis Clinical Site #154 Active, not recruiting Houston Texas 77030 United States Details
Exelixis Clinical Site #19 Active, not recruiting Temple Texas 76508 United States Details
Exelixis Clinical Site #13 Active, not recruiting Seattle Washington 98101 United States Details
Exelixis Clinical Site #46 Active, not recruiting Seattle Washington 98109 United States Details
Exelixis Clinical Site #3 Active, not recruiting Spokane Washington 99208 United States Details
Exelixis Clinical Site #217 Active, not recruiting City of Buenos Aires Buenos Aires C1118AAT Argentina Details
Exelixis Clinical Site #213 Active, not recruiting City of Buenos Aires Buenos Aires C1199ABB Argentina Details
Exelixis Clinical Site #216 Active, not recruiting City of Buenos Aires Buenos Aires C1264AAA Argentina Details
Exelixis Clinical Site #219 Active, not recruiting Pilar Buenos Aires B1629ODT Argentina Details
Exelixis Clinical Site #220 Active, not recruiting Rosario Santa Fe 2000 Argentina Details
Exelixis Clinical Site #201 Active, not recruiting Rosario Santa Fe S2000CVB Argentina Details
Exelixis Clinical Site #78 Active, not recruiting Camperdown New South Wales 2050 Australia Details
Exelixis Clinical Site #165 Active, not recruiting Darlinghurst New South Wales 2010 Australia Details
Exelixis Clinical Site #171 Active, not recruiting Kingswood New South Wales 2747 Australia Details
Exelixis Clinical Site #126 Active, not recruiting Kogarah New South Wales 2217 Australia Details
Exelixis Clinical Site #155 Active, not recruiting Westmead New South Wales 2145 Australia Details
Exelixis Clinical Site #142 Active, not recruiting Greenslopes Queensland 4120 Australia Details
Exelixis Clinical Site #17 Active, not recruiting Kurralta Park South Australia Australia Details
Exelixis Clinical Site #107 Active, not recruiting Box Hill Victoria 3128 Australia Details
Exelixis Clinical Site #166 Active, not recruiting Heidelberg Victoria 3084 Australia Details
Exelixis Clinical Site #72 Active, not recruiting Parkville Victoria 3050 Australia Details
Exelixis Clinical Site #190 Active, not recruiting Nedlands Western Australia 6009 Australia Details
Exelixis Clinical Site #150 Active, not recruiting Klagenfurt Kärnten 9020 Austria Details
Exelixis Clinical Site #137 Active, not recruiting St. Pölten Lower Austria 3100 Austria Details
Exelixis Clinical Site #64 Active, not recruiting Linz Oberosterreich 4010 Austria Details
Exelixis Clinical Site #198 Active, not recruiting Graz Steiermark 8036 Austria Details
Exelixis Clinical Site #174 Active, not recruiting Wien 1090 Austria Details
Exelixis Clinical Site #50 Active, not recruiting Brussels California 1070 Belgium Details
Exelixis Clinical Site #65 Active, not recruiting Brussels 1200 Belgium Details
Exelixis Clinical Site #169 Active, not recruiting Edegem 2650 Belgium Details
Exelixis Clinical Site #148 Active, not recruiting Gent 9000 Belgium Details
Exelixis Clinical Site #57 Active, not recruiting Haine-Saint-Paul 7100 Belgium Details
Exelixis Clinical Site #188 Active, not recruiting Leuven 3000 Belgium Details
Exelixis Clinical Site #102 Active, not recruiting Liège 4000 Belgium Details
Exelixis Clinical Site #184 Active, not recruiting Salvador BA 40110-060 Brazil Details
Exelixis Clinical Site #89 Active, not recruiting Belo Horizonte MG 30110-022 Brazil Details
Exelixis Clinical Site #98 Active, not recruiting Belo Horizonte MG 30130-090 Brazil Details
Exelixis Clinical Site #113 Active, not recruiting Curitiba PR 81520-060 Brazil Details
Exelixis Clinical Site #203 Active, not recruiting Porto Alegre RS 90050-170 Brazil Details
Exelixis Clinical Site #175 Active, not recruiting Barretos SP 14784-400 Brazil Details
Exelixis Clinical Site #121 Active, not recruiting Jaú SP 17210-120 Brazil Details
Exelixis Clinical Site #186 Active, not recruiting São Paulo SP 01246-900 Brazil Details
Exelixis Clinical Site #156 Active, not recruiting São Paulo SP 01321-001 Brazil Details
Exelixis Clinical Site #187 Active, not recruiting São Paulo SP 01509-010 Brazil Details
Exelixis Clinical Site #181 Active, not recruiting São Paulo SP 04538-132 Brazil Details
Exelixis Clinical Site #91 Active, not recruiting São Paulo 04543-000 Brazil Details
Exelixis Clinical Site #71 Active, not recruiting Calgary Alberta T2N 4N2 Canada Details
Exelixis Clinical Site #205 Active, not recruiting Edmonton Alberta T6G 2B7 Canada Details
Exelixis Clinical Site #34 Active, not recruiting Winnipeg Manitoba R3E 0V9 Canada Details
Exelixis Clinical Site #222 Active, not recruiting Halifax Nova Scotia B3H 2Y9 Canada Details
Exelixis Clinical Site #194 Active, not recruiting Hamilton Ontario L8V 5C2 Canada Details
Exelixis Clinical Site #212 Active, not recruiting Ottawa Ontario K1H 8L6 Canada Details
Exelixis Clinical Site #85 Active, not recruiting Montréal Quebec H3T 1E2 Canada Details
Exelixis Clinical Site #233 Recruiting Hefei Anhui 230036 China Details
Exelixis Clinical Site #228 Recruiting Fuzhou Fujian 350014 China Details
Exelixis Clinical Site #225 Recruiting Xiamen Fujian 361004 China Details
Exelixis Clinical Site #242 Recruiting Guangzhou Guangdong 510280 China Details
Exelixis Clinical Site #227 Recruiting Harbin Heilongjiang 150081 China Details
Exelixis Clinical Site #230 Recruiting Zhengzhou Henan 450008 China Details
Exelixis Clinical Site #231 Recruiting Changsha Hunan 410008 China Details
Exelixis Clinical Site #224 Recruiting Changsha Hunan 410013 China Details
Exelixis Site #241 Recruiting Changsha Hunan 410013 China Details
Exelixis Clinical Site #185 Recruiting Nanjing Jiangsu 210002 China Details
Exelixis Clinical Site #245 Recruiting Nantong Jiangsu 226361 China Details
Exelixis Clinical Site #221 Recruiting Nanchang Jiangxi 330006 China Details
Exelixis Clinical Site #238 Recruiting Nanchang Jiangxi 330006 China Details
Exelixis Clinical Site #234 Recruiting Jiangyin Jiansu 214400 China Details
Exelixis Clinical Site #246 Recruiting Changchun Jilin 130012 China Details
Exelixis Clinical Site #229 Recruiting Changchun Jilin 130021 China Details
Exelixis Clinical Site #236 Recruiting Shenyang Liaoning 110006 China Details
Exelixis Clinical Site #226 Recruiting Linyi Shandong 276000 China Details
Exelixis Clinical Site #235 Recruiting Chengdu Sichuan 610041 China Details
Exelixis Clinical Site #218 Recruiting Hangzhou Zhejiang 310016 China Details
Exelixis Clinical Site #223 Recruiting Hangzhou Zhejiang 310022 China Details
Exelixis Site #239 Recruiting Beijing 100034 China Details
Exelixis Clinical Site #237 Recruiting Beijing 100050 China Details
Exelixis Site #240 Recruiting Shanghai 200001 China Details
Exelixis Clinical Site #232 Recruiting Shanghai 201305 China Details
Exelixis Clinical Site #130 Active, not recruiting Montería Cordoba 230002 Colombia Details
Exelixis Clinical Site #18 Active, not recruiting Hradec Králové 500 05 Czechia Details
Exelixis Clinical Site #37 Active, not recruiting Olomouc 779 00 Czechia Details
Exelixis Clinical Site #10 Active, not recruiting Praha 4 140 59 Czechia Details
Exelixis Clinical Site #38 Active, not recruiting Praha 5 150 06 Czechia Details
Exelixis Clinical Site #43 Active, not recruiting Amiens 80054 France Details
Exelixis Clinical Site #27 Active, not recruiting Besancon 25030 France Details
Exelixis Clinical Site #56 Active, not recruiting Bondy Cedex 93140 France Details
Exelixis Clinical Site #29 Active, not recruiting Caen Cedex 09 14033 France Details
Exelixis Clinical Site #48 Active, not recruiting Clichy 92110 France Details
Exelixis Clinical Site #23 Active, not recruiting Grenoble 38043 France Details
Exelixis Clinical Site #55 Active, not recruiting Lille Cedex 59037 France Details
Exelixis Clinical Site #16 Active, not recruiting Lyon Cedex 4 69317 France Details
Exelixis Clinical Site #31 Active, not recruiting Montbeliard 25250 France Details
Exelixis Clinical Site #49 Active, not recruiting Montpellier 34295 France Details
Exelixis Clinical Site #47 Active, not recruiting Nantes 44093 France Details
Exelixis Clinical Site #51 Active, not recruiting Nice 06202 France Details
Exelixis Clinical Site #20 Active, not recruiting Pessac 33604 France Details
Exelixis Clinical Site #32 Active, not recruiting Vandœuvre-lès-Nancy 54511 France Details
Exelixis Clinical Site #69 Active, not recruiting Batumi 6000 Georgia Details
Exelixis Clinical Site #66 Active, not recruiting Tbilisi 0112 Georgia Details
Exelixis Clinical Site #68 Active, not recruiting Tbilisi 0114 Georgia Details
Exelixis Clinical Site #67 Active, not recruiting Tbilisi 0144 Georgia Details
Exelixis Clinical Site #70 Active, not recruiting Tbilisi 0186 Georgia Details
Exelixis Clinical Site #244 Recruiting Frankfurt Hessen 60590 Germany Details
Exelixis Clinical Site #210 Active, not recruiting Kassel Hessen 34125 Germany Details
Exelixis Clinical Site #214 Active, not recruiting Berlin 13125 Germany Details
Exelixis Clinical Site #215 Active, not recruiting Hamburg 20246 Germany Details
Exelixis Clinical Site #146 Active, not recruiting Hong Kong Hong Kong Details
Exelixis Clinical Site #42 Active, not recruiting Hong Kong Hong Kong Details
Exelixis Clinical Site #9 Active, not recruiting Hong Kong Hong Kong Details
Exelixis Clinical Site #140 Active, not recruiting Budapest 1083 Hungary Details
Exelixis Clinical Site #25 Active, not recruiting Debrecen 4032 Hungary Details
Exelixis Clinical Site #26 Active, not recruiting Szeged 6720 Hungary Details
Exelixis Clinical Site #170 Active, not recruiting Dublin 8 Ireland Details
Exelixis Clinical Site #30 Active, not recruiting Jerusalem 9112001 Israel Details
Exelixis Clinical Site #33 Active, not recruiting Petah Tikva 4941492 Israel Details
Exelixis Clinical Site #40 Active, not recruiting Ramat-Gan 5262101 Israel Details
Exelixis Clinical Site #35 Active, not recruiting Rehovot 7661041 Israel Details
Exelixis Clinical Site #163 Active, not recruiting Tricase Lecce 73039 Italy Details
Exelixis Clinical Site #53 Active, not recruiting Rozzano Milano 20089 Italy Details
Exelixis Clinical Site #158 Active, not recruiting Bologna 40138 Italy Details
Exelixis Clinical Site #152 Active, not recruiting Brescia 25124 Italy Details
Exelixis Clinical Site #147 Active, not recruiting Milan 20122 Italy Details
Exelixis Clinical Site #149 Active, not recruiting Napoli 80131 Italy Details
Exelixis Clinical Site #131 Active, not recruiting Novara 28100 Italy Details
Exelixis Clinical Site #167 Active, not recruiting Roma 00168 Italy Details
Exelixis Clinical Site #177 Active, not recruiting Torino 10126 Italy Details
Exelixis Clinical Site #182 Active, not recruiting Torino 10128 Italy Details
Exelixis Clinical Site #243 Recruiting Udine 33100 Italy Details
Exelixis Clinical Site #157 Active, not recruiting Goyang-si Gyeonggi-do 10408 Korea, Republic of Details
Exelixis Clinical Site #127 Active, not recruiting Suwon Gyeonggi-do 16499 Korea, Republic of Details
Exelixis Clinical Site #77 Active, not recruiting Busan 47392 Korea, Republic of Details
Exelixis Clinical Site #86 Active, not recruiting Busan 49201 Korea, Republic of Details
Exelixis Clinical Site #114 Active, not recruiting Busan 49241 Korea, Republic of Details
Exelixis Clinical Site #75 Active, not recruiting Incheon 22332 Korea, Republic of Details
Exelixis Clinical Site #104 Active, not recruiting Seoul 03080 Korea, Republic of Details
Exelixis Clinical Site #105 Active, not recruiting Seoul 03080 Korea, Republic of Details
Exelixis Clinical Site #99 Active, not recruiting Seoul 05505 Korea, Republic of Details
Exelixis Clinical Site #79 Active, not recruiting Seoul 06273 Korea, Republic of Details
Exelixis Clinical Site #93 Active, not recruiting Seoul 06351 Korea, Republic of Details
Exelixis Clinical Site #141 Active, not recruiting Tuxtla Gutiérrez Chiapas 29038 Mexico Details
Exelixis Clinical Site #135 Active, not recruiting León Guanajuato 37000 Mexico Details
Exelixis Clinical Site #132 Active, not recruiting Monterrey Nuevo Leon 64000 Mexico Details
Exelixis Clinical Site #133 Active, not recruiting Ciudad De México 06700 Mexico Details
Exelixis Clinical Site #160 Active, not recruiting Mexico City 06760 Mexico Details
Exelixis Clinical Site #134 Active, not recruiting San Luis Potosí 78250 Mexico Details
Exelixis Clinical Site #153 Active, not recruiting Veracruz 94300 Mexico Details
Exelixis Clinical Site #92 Active, not recruiting Maastricht Limburg 6229 HX Netherlands Details
Exelixis Clinical Site #52 Active, not recruiting Amsterdam Noord-Holland 1105 AZ Netherlands Details
Exelixis Clinical Site #84 Active, not recruiting Rotterdam Zuid-Holland 3015 GD Netherlands Details
Exelixis Clinical Site #36 Active, not recruiting Utrecht 3584 CX Netherlands Details
Exelixis Clinical Site #60 Active, not recruiting Grafton Auckland 1023 New Zealand Details
Exelixis Clinical Site #62 Active, not recruiting Newton Wellington 6021 New Zealand Details
Exelixis Clinical Site #118 Active, not recruiting Cebu City 6000 Philippines Details
Exelixis Clinical Site #117 Active, not recruiting Pasig City 1605 Philippines Details
Exelixis Clinical Site #136 Active, not recruiting Quezon City 1102 Philippines Details
Exelixis Clinical Site #41 Active, not recruiting Warszawa Mazowieckie 02-507 Poland Details
Exelixis Clinical Site #24 Active, not recruiting Gdansk Pomorskie 80-952 Poland Details
Exelixis Clinical Site #15 Active, not recruiting Mysłowice Slaskie 41-400 Poland Details
Exelixis Clinical Site #204 Active, not recruiting Cluj-Napoca Cluj 400015 Romania Details
Exelixis Clinical Site #211 Active, not recruiting Cluj-Napoca Cluj 400015 Romania Details
Exelixis Clinical Site #202 Active, not recruiting Cluj-Napoca Cluj 400641 Romania Details
Exelixis Clinical Site #206 Active, not recruiting Bucuresti 022328 Romania Details
Exelixis Clinical Site #209 Active, not recruiting Iaşi 700483 Romania Details
Exelixis Clinical Site #74 Active, not recruiting Kislino Kursk Region 305524 Russian Federation Details
Exelixis Clinical Site #81 Active, not recruiting Kaluga 248007 Russian Federation Details
Exelixis Clinical Site #95 Active, not recruiting Krasnodar 350040 Russian Federation Details
Exelixis Clinical Site #108 Active, not recruiting Moscow 115478 Russian Federation Details
Exelixis Clinical Site #101 Active, not recruiting Murmansk 183047 Russian Federation Details
Exelixis Clinical Site #80 Active, not recruiting Nizhny Novgorod 603137 Russian Federation Details
Exelixis Clinical Site #111 Active, not recruiting Saint Petersburg 197758 Russian Federation Details
Exelixis Clinical Site #90 Active, not recruiting Saint-Petersburg 197758 Russian Federation Details
Exelixis Clinical Site #73 Active, not recruiting Sochi 354057 Russian Federation Details
Exelixis Clinical Site #106 Active, not recruiting Singapore 169610 Singapore Details
Exelixis Clinical Site #97 Active, not recruiting Singapore 217562 Singapore Details
Exelixis Clinical Site #116 Active, not recruiting Singapore 308433 Singapore Details
Exelixis Clinical Site #28 Active, not recruiting Santander Cantabria 39008 Spain Details
Exelixis Clinical Site #21 Active, not recruiting Majadahonda Madrid 28222 Spain Details
Exelixis Clinical Site #22 Active, not recruiting Majadahonda Madrid 28222 Spain Details
Exelixis Clinical Site #59 Active, not recruiting Pamplona Navarra 31008 Spain Details
Exelixis Clinical Site #103 Active, not recruiting Barcelona 08908 Spain Details
Exelixis Clinical Site #164 Active, not recruiting Madrid 28007 Spain Details
Exelixis Clinical Site #63 Active, not recruiting Madrid 28046 Spain Details
Exelixis Clinical Site #168 Active, not recruiting Valencia 46009 Spain Details
Exelixis Clinical Site #45 Active, not recruiting Zaragoza 50009 Spain Details
Exelixis Clinical Site #115 Active, not recruiting Basel 4031 Switzerland Details
Exelixis Clinical Site #172 Active, not recruiting Bern 3010 Switzerland Details
Exelixis Clinical Site #110 Active, not recruiting Saint Gallen 9007 Switzerland Details
Exelixis Clinical Site #61 Active, not recruiting Zurich 8091 Switzerland Details
Exelixis Clinical Site #119 Active, not recruiting Changhua 500 Taiwan Details
Exelixis Clinical Site #162 Active, not recruiting Kaohsiung 833 Taiwan Details
Exelixis Clinical Site #161 Active, not recruiting Taichung 407 Taiwan Details
Exelixis Clinical Site #197 Active, not recruiting Tainan City 704 Taiwan Details
Exelixis Clinical Site #145 Active, not recruiting Tainan 736 Taiwan Details
Exelixis Clinical Site #82 Active, not recruiting Taipei 10002 Taiwan Details
Exelixis Clinical Site #128 Active, not recruiting Taipei 10491 Taiwan Details
Exelixisi Clinical Site #100 Active, not recruiting Taipei 11217 Taiwan Details
Exelixis Clinical Site #94 Active, not recruiting Taoyuan 333 Taiwan Details
Exelixis Clinical Site #96 Active, not recruiting Pathum Wan Bangkok 10330 Thailand Details
Exelixis Clinical Site #183 Active, not recruiting Muang Khon Kaen 40002 Thailand Details
Exelixis Clinical Site #139 Active, not recruiting Hat Yai Songkla 90110 Thailand Details
Exelixis Clinical Site #143 Active, not recruiting Chiang Mai 50200 Thailand Details
Exelixis Clinical Site #189 Active, not recruiting Istanbul Instanbul 34098 Turkey Details
Exelixis Clinical Site #193 Active, not recruiting Ankara 06010 Turkey Details
Exelixis Clinical Site #178 Active, not recruiting Ankara 06230 Turkey Details
Exelixis Clinical Site #173 Active, not recruiting Edirne 22030 Turkey Details
Exelixis Clinical Site #179 Active, not recruiting Istanbul 34214 Turkey Details
Exelixis Clinical Site #180 Active, not recruiting Malatya 44280 Turkey Details
Exelixis Clinical Site #125 Active, not recruiting Chernivtsi 58013 Ukraine Details
Exelixis Clinical Site #122 Active, not recruiting Dnipro 49102 Ukraine Details
Exelixis Clinical Site #123 Active, not recruiting Kharkiv 61070 Ukraine Details
Exelixis Clinical Site #124 Active, not recruiting Odesa 65055 Ukraine Details
Exelixis Clinical Site #138 Active, not recruiting Uzhhorod 88000 Ukraine Details
Exelixis Clinical Site #83 Active, not recruiting Bristol England BS2 8ED United Kingdom Details
Exelixis Clinical Site #87 Active, not recruiting Cambridge England CB2 0QQ United Kingdom Details
Exelixis Clinical Site #151 Active, not recruiting London England NW3 2QG United Kingdom Details
Exelixis Clinical Site #129 Active, not recruiting London England W12 0HS United Kingdom Details
Exelixis Clinical Site #192 Active, not recruiting Manchester England M20 4BX United Kingdom Details
Exelixis Clinical Site #196 Active, not recruiting Belfast Northern Ireland BT9 7AB United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field