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NCT ID NCT03765918
Title Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.

oral cavity cancer

larynx cancer

hypopharynx cancer

oropharynx cancer



Cisplatin + Pembrolizumab


Age Groups: senior | adult
Covered Countries USA | FRA | ESP | DEU | CAN | BEL | AUT

Facility Status City State Zip Country Details
Moores Cancer Center ( Site 1885) Recruiting La Jolla California 92093-0698 United States Details
University of Southern California Norris Comprehensive Cancer Center ( Site 1850) Completed Los Angeles California 90033 United States Details
UC Davis Health System ( Site 1864) Recruiting Sacramento California 95817 United States Details
St. Joseph Heritage Healthcare ( Site 1806) Recruiting Santa Rosa California 95403 United States Details
University of Colorado Cancer Center ( Site 1838) Recruiting Aurora Colorado 80045 United States Details
George Washington University Medical Faculty Associates ( Site 2035) Completed Washington District of Columbia 20037 United States Details
University of Florida ( Site 1832) Completed Gainesville Florida 32608 United States Details
University of Miami, Sylvester Comprehensive Cancer Center ( Site 2008) Completed Miami Florida 33136 United States Details
AdventHealth Orlando-AdventHealth Medical Group Hematology & Oncology at Orlando ( Site 2054) Recruiting Orlando Florida 32804 United States Details
Saint Alphonsus Regional Medical Center ( Site 2021) Completed Boise Idaho 83706 United States Details
Beacon Cancer Care ( Site 2052) Recruiting Coeur d'Alene Idaho 83814 United States Details
Rush University Medical Center ( Site 1823) Recruiting Chicago Illinois 60612 United States Details
NorthShore University HealthSystem ( Site 1812) Recruiting Evanston Illinois 60201 United States Details
Loyola University Medical Center [Maywood, IL] ( Site 1817) Recruiting Maywood Illinois 60153 United States Details
University of Kansas Cancer Center ( Site 2004) Recruiting Westwood Kansas 66205 United States Details
Ochsner Cancer Institute ( Site 2045) Recruiting New Orleans Louisiana 70121 United States Details
University of Maryland ( Site 2031) Recruiting Baltimore Maryland 21201 United States Details
Dana Farber Cancer Center ( Site 1873) Recruiting Boston Massachusetts 02215 United States Details
University of Massachusetts Memorial Medical Center ( Site 1875) Completed Worcester Massachusetts 01655 United States Details
Karmanos Cancer Institute ( Site 1870) Recruiting Detroit Michigan 48201 United States Details
Henry Ford Health System ( Site 1803) Recruiting Detroit Michigan 48202 United States Details
Southdale Cancer Care, University of Minnesota Medical Center- Edina ( Site 2016) Completed Edina Minnesota 55435 United States Details
Washington University School of Medicine ( Site 1800) Recruiting Saint Louis Missouri 63110 United States Details
Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center ( Site 1897) Completed Springfield Missouri 65804 United States Details
St. Vincent Healthcare Frontier Cancer Center ( Site 1818) Completed Billings Montana 59102 United States Details
Memorial Sloan Kettering Cancer Center Basking Ridge ( Site 2036) Recruiting Basking Ridge New Jersey 07920 United States Details
Memorial Sloan Kettering Cancer Center- Monmouth ( Site 2039) Recruiting Middletown New Jersey 07748 United States Details
MSKCC-Bergen ( Site 2037) Recruiting Montvale New Jersey 07645 United States Details
Rutgers New Jersey Medical School-department of Hematology oncology ( Site 2053) Recruiting Newark New Jersey 07101 United States Details
The University of New Mexico Comprehensive Cancer Center ( Site 1882) Completed Albuquerque New Mexico 87131 United States Details
Montefiore Einstein Center ( Site 2028) Recruiting Bronx New York 10467 United States Details
Erie County Medical Center ( Site 2047) Recruiting Buffalo New York 14215 United States Details
Memorial Sloan-Kettering Cancer Center at Commack ( Site 2038) Recruiting Commack New York 11725 United States Details
Memorial Sloan-Kettering Cancer Center at West Harrison ( Site 2041) Recruiting Harrison New York 10604 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 2014) Recruiting New York New York 10016 United States Details
Memorial Sloan Kettering Cancer Center ( Site 1857) Recruiting New York New York 10065 United States Details
Weill Cornell Medical College ( Site 2050) Recruiting New York New York 10065 United States Details
Northwell Health Cancer Institute ( Site 2030) Recruiting New York New York 10075 United States Details
Memorial Sloan Kettering Cancer Center - Nassau ( Site 2040) Recruiting Uniondale New York 11553 United States Details
Levine Cancer Institute ( Site 2003) Recruiting Charlotte North Carolina 28204 United States Details
Wake Forest Compenhensive Cancer Center ( Site 2029) Completed Winston-Salem North Carolina 27357 United States Details
Sanford Health Roger Maris Cancer Center ( Site 2034) Recruiting Fargo North Dakota 58122 United States Details
University Hospitals ( Site 2032) Completed Cleveland Ohio 44106 United States Details
The Ohio State University ( Site 2012) Completed Columbus Ohio 43210 United States Details
Providence Portland Medical Center ( Site 1843) Recruiting Portland Oregon 97220 United States Details
Kaiser Permanente Center for Health Research-Kaiser Permanente Medical Center ( Site 2022) Completed Portland Oregon 97227 United States Details
Oregon Health Sciences University ( Site 1871) Completed Portland Oregon 97239 United States Details
St. Luke's University Health Network ( Site 1801) Recruiting Bethlehem Pennsylvania 18015 United States Details
Allegheny General Hospital ( Site 1833) Recruiting Pittsburgh Pennsylvania 15212 United States Details
Sanford Cancer Center Oncology Clinic ( Site 1859) Recruiting Sioux Falls South Dakota 57104 United States Details
Henry Joyce Cancer Clinic ( Site 1827) Recruiting Nashville Tennessee 37232 United States Details
UT Southwestern Medical Center ( Site 1841) Recruiting Dallas Texas 75390 United States Details
University of Utah, Huntsman Cancer Institute ( Site 1855) Recruiting Salt Lake City Utah 84112 United States Details
University of Vermont Medical Center ( Site 2009) Recruiting Burlington Vermont 05401 United States Details
UVA Health System - Emily Couric Cancer Center ( Site 1826) Recruiting Charlottesville Virginia 22908 United States Details
Inova Schar Cancer Institute ( Site 2026) Completed Fairfax Virginia 22031 United States Details
Seattle Cancer Care Alliance/Univ of Washington Medical Center ( Site 1865) Recruiting Seattle Washington 98109 United States Details
Hospital Universitario Austral ( Site 0009) Completed Pilar Buenos Aires B1629AHJ Argentina Details
Hospital Britanico de Buenos Aires ( Site 0012) Recruiting Ciudad de Buenos Aires Caba C1280AEB Argentina Details
Fundacion Estudios Clinicos-Oncology ( Site 0017) Recruiting Rosario Santa Fe 2000 Argentina Details
Sanatorio Britanico ( Site 0013) Recruiting Rosario Santa Fe S2000CVB Argentina Details
Instituto de Oncologia de Rosario ( Site 0002) Recruiting Rosario Santa Fe S2000KZE Argentina Details
Hospital Provincial del Centenario ( Site 0008) Recruiting Rosario Santa Fe S2002KDS Argentina Details
IDIM - Instituto de Diagnóstico e Investigaciones Metabólicas ( Site 0016) Recruiting Buenos Aires C1012AAR Argentina Details
Hospital Aleman Buenos Aires Argentina ( Site 0004) Recruiting Buenos Aires C1118AAT Argentina Details
Instituto de Oncología Angel Roffo ( Site 0003) Completed Buenos Aires C1417DTB Argentina Details
CER San Juan Centro Polivalente de Asistencia e Investigacion Clinica ( Site 0010) Recruiting San Juan J5402DIL Argentina Details
The Crown Princess Mary Cancer Centre - Westmead Hospital ( Site 0051) Completed Westmead New South Wales 2145 Australia Details
Royal Brisbane and Women s Hospital ( Site 0050) Recruiting Herston Queensland 4029 Australia Details
Ordensklinikum Linz Gmbh - Barmherzige Schwestern ( Site 1901) Recruiting Linz Oberosterreich 4010 Austria Details
Landeskrankenhaus - Universitatsklinikum Graz ( Site 1902) Recruiting Graz Steiermark 8036 Austria Details
Landeskrankenhaus Salzburg - Universitatklinikum der PMU ( Site 1900) Recruiting Salzburg 5020 Austria Details
Medizinische Universität Wien ( Site 1903) Recruiting Wien 1090 Austria Details
Hopital de Jolimont ( Site 0103) Recruiting Haine Saint Paul Hainaut 7100 Belgium Details
UZ Gent ( Site 0101) Recruiting Gent Oost-Vlaanderen 9000 Belgium Details
AZ Nikolaas ( Site 0104) Recruiting Sint-Niklaas Oost-Vlaanderen 9100 Belgium Details
Hospital Santa Izabel - Santa Casa de Misericordia da Bahia ( Site 0155) Recruiting Salvador Bahia 40050-410 Brazil Details
Centro Regional Integrado de Oncologia ( Site 0160) Recruiting Fortaleza Ceara 60336-232 Brazil Details
Hospital Marcio Cunha-Unidade de Pesquisa Clínica ( Site 0177) Recruiting Ipatinga Minas Gerais 35162-189 Brazil Details
Liga Norte Riograndense Contra o Cancer ( Site 0171) Recruiting Natal Rio Grande Do Norte 59075-740 Brazil Details
Hospital Nossa Senhora da Conceicao ( Site 0165) Recruiting Porto Alegre Rio Grande Do Sul 91359-200 Brazil Details
Hospital de Base de Sao Jose de Rio Preto ( Site 0153) Recruiting Sao Jose do Rio Preto Sao Paulo 15090-000 Brazil Details
Instituto Nacional do Cancer Jose Alencar Gomes da Silva INCA ( Site 0169) Recruiting Rio de Janeiro 20231-050 Brazil Details
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0167) Recruiting Sao Paulo 01246-000 Brazil Details
BP - A Beneficencia Portuguesa de São Paulo-Medical Oncology ( Site 0175) Recruiting Sao Paulo 01321-001 Brazil Details
Cross Cancer Institute ( Site 0201) Recruiting Edmonton Alberta T6G 1Z2 Canada Details
Princess Margaret Cancer Centre ( Site 0202) Recruiting Toronto Ontario M5G 2M9 Canada Details
McGill University Health Centre ( Site 0210) Recruiting Montreal Quebec H4A 3J1 Canada Details
CIUSSS de l'Estrie-CHUS ( Site 0209) Recruiting Sherbrooke Quebec J1H 5N4 Canada Details
Fundacion Arturo Lopez Perez FALP ( Site 0251) Recruiting Santiago Region M. De Santiago 7500921 Chile Details
Clinica de la Costa Ltda. ( Site 0307) Recruiting Barranquilla Atlantico 080020 Colombia Details
Centro de Investigacion Clinica del Country ( Site 0304) Completed Bogota Distrito Capital De Bogota 110221 Colombia Details
Oncologos del Occidente S.A. ( Site 0310) Recruiting Pereira Risaralda 661002 Colombia Details
Centro Medico Imbanaco de Cali S.A ( Site 0300) Completed Cali Valle Del Cauca 760042 Colombia Details
Centre Antoine Lacassagne ( Site 0351) Recruiting Nice Alpes-Maritimes 06189 France Details
Hopital de la Timone ( Site 0356) Recruiting Marseille Bouches-du-Rhone 13005 France Details
Institut Claudius Regaud IUCT Oncopole ( Site 0355) Completed Toulouse Haute-Garonne 31059 France Details
Institut Gustave Roussy ( Site 0353) Recruiting Villejuif Val-de-Marne 94800 France Details
Institut Sainte Catherine ( Site 0352) Recruiting Avignon Vaucluse 84918 France Details
Hopital Europeen Georges Pompidou ( Site 0358) Recruiting Paris 75015 France Details
Institut Curie ( Site 0350) Recruiting Paris 75248 France Details
Universitaetsklinikum Tuebingen - Medizinische Klinik ( Site 0401) Recruiting Tuebingen Baden-Wurttemberg 72076 Germany Details
Universitaetsklinikum Ulm ( Site 0402) Recruiting Ulm Baden-Wurttemberg 89075 Germany Details
Klinikum rechts der Isar der Technischen Universitaet ( Site 0409) Recruiting Muenchen Bayern 81675 Germany Details
Klinikum rechts der Isar der Technischen Universität München-HNO Klinik ( Site 0405) Completed München Bayern 81675 Germany Details
Universitaetsklinikum Frankfurt ( Site 0403) Recruiting Frankfurt Hessen 60590 Germany Details
Klinikum Kassel GmbH ( Site 0404) Completed Kassel Hessen 34125 Germany Details
Universitätsklinikum Schleswig-Holstein ( Site 0411) Recruiting Luebeck Schleswig-Holstein 23538 Germany Details
SRH Wald-Klinikum Gera GmbH ( Site 0406) Completed Gera Thuringen 07548 Germany Details
Universitaetsklinikum Hamburg Eppendorf ( Site 0407) Recruiting Hamburg 20246 Germany Details
Pecsi Tudomanyegyetem Onkoterapias Intezet ( Site 0452) Recruiting Pecs Baranya 7621 Hungary Details
Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet ( Site 0450) Recruiting Szolnok Jasz-Nagykun-Szolnok 5000 Hungary Details
Magyar Honvedseg Egeszsegugyi Kozpont ( Site 0453) Recruiting Budapest 1062 Hungary Details
Orszagos Onkologiai Intezet ( Site 0454) Recruiting Budapest 1122 Hungary Details
St. James s Hospital ( Site 0500) Recruiting Dublin D08 K0Y5 Ireland Details
Rambam Health Care Campus-Oncology Division ( Site 0550) Recruiting Haifa 3109601 Israel Details
Hadassah Medical Center. Ein Kerem ( Site 0554) Recruiting Jerusalem 9112001 Israel Details
Rabin Medical Center ( Site 0552) Recruiting Petah Tikva 49100 Israel Details
Chaim Sheba Medical Center. ( Site 0553) Recruiting Ramat Gan 5265601 Israel Details
Sourasky Medical Center ( Site 0551) Completed Tel Aviv 6423906 Israel Details
Aichi Cancer Center Hospital ( Site 0658) Recruiting Nagoya Aichi 464-8681 Japan Details
National Cancer Center Hospital East ( Site 0661) Recruiting Kashiwa Chiba 277-8577 Japan Details
Hyogo Cancer Center ( Site 0656) Recruiting Akashi Hyogo 673-8558 Japan Details
Kagawa University Hospital ( Site 0651) Recruiting Kita-gun Kagawa 761-0793 Japan Details
Yokohama City University Hospital ( Site 0657) Recruiting Yokohama Kanagawa 236-0004 Japan Details
Chiba Cancer Center ( Site 0652) Recruiting Chiba 260-8717 Japan Details
National Hospital Organization Kyushu Cancer Center ( Site 0660) Recruiting Fukuoka 811-1395 Japan Details
Hiroshima University Hospital ( Site 0655) Recruiting Hiroshima 734-8551 Japan Details
National Cancer Center Hospital ( Site 0650) Recruiting Tokyo 104-0045 Japan Details
Tokyo Medical University Hospital ( Site 0659) Recruiting Tokyo 160-0023 Japan Details
Tokyo Medical and Dental University Hospital ( Site 0654) Recruiting Tokyo Japan Details
Chonnam National University Hwasun Hospital ( Site 0705) Recruiting Hwasun Gun Jeonranamdo 58128 Korea, Republic of Details
National Cancer Center ( Site 0702) Completed Goyang-si Kyonggi-do 10408 Korea, Republic of Details
The Catholic University of Korea St. Vincent s Hospital ( Site 0704) Recruiting Gyeonggi-do Kyonggi-do 16247 Korea, Republic of Details
Seoul National University Bundang Hospital ( Site 0703) Recruiting Seongnam-si Kyonggi-do 13620 Korea, Republic of Details
Wojewodzki Szpital Specjalistyczny im. M. Kopernika w Lodzi ( Site 0920) Completed Lodz Lodzkie 93-513 Poland Details
Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie ( Site 0905) Recruiting Krakow Malopolskie 31-826 Poland Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Recruiting Warszawa Mazowieckie 02-781 Poland Details
Szpitale Pomorskie Sp. z o.o. ( Site 0935) Recruiting Gdynia Pomorskie 81-159 Poland Details
Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 0901) Recruiting Gliwice Slaskie 44-101 Poland Details
Hospital de Braga ( Site 0951) Recruiting Braga 4710-243 Portugal Details
CHLN Hospital Santa Maria ( Site 0952) Recruiting Lisboa 1649-035 Portugal Details
Hospital CUF Descobertas ( Site 0953) Recruiting Lisboa 1998-018 Portugal Details
Inst. Portugues de Oncologia de Porto Francisco Gentil EPE ( Site 0950) Recruiting Porto 4200-072 Portugal Details
N.N. Blokhin NMRCO ( Site 1005) Suspended Moscow Moskva 115478 Russian Federation Details
Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 1000) Suspended Kazan Tatarstan, Respublika 420029 Russian Federation Details
Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 1001) Suspended Yaroslavl Yaroslavskaya Oblast 150054 Russian Federation Details
Hospital Germans Trias i Pujol. ICO de Badalona ( Site 1204) Recruiting Badalona Barcelona 08916 Spain Details
ICO L Hospitalet ( Site 1208) Recruiting Hospitalet de Llobregat Barcelona 08908 Spain Details
Hospital Clinico Universitario de Santiago ( Site 1207) Recruiting Santiago de Compostela La Coruna 15706 Spain Details
Hospital Vall D Hebron ( Site 1200) Recruiting Barcelona 08035 Spain Details
Hospital Universitario La Paz ( Site 1201) Recruiting Madrid 28046 Spain Details
Hospital Universitario Virgen del Rocio ( Site 1206) Recruiting Sevilla 41013 Spain Details
Universitaetsspital Zurich ( Site 1923) Completed Zuerich Aargau 8091 Switzerland Details
Istituto Oncologica della Svizzera Italiana (IOSI) ( Site 1921) Recruiting Bellinzona Ticino 6500 Switzerland Details
Hopitaux Universitaires de Geneve HUG ( Site 1920) Recruiting Geneve 1211 Switzerland Details
Chang Gung Medical Foundation. Kaohsiung Branch ( Site 1303) Recruiting Kaohsiung 833 Taiwan Details
Taichung Veterans General Hospital ( Site 1301) Recruiting Taichung 40705 Taiwan Details
National Cheng Kung University Hospital ( Site 1302) Recruiting Tainan 704 Taiwan Details
National Taiwan University Hospital ( Site 1300) Recruiting Taipei 10002 Taiwan Details
Dnipropetrovsk Regional Hospital n.a. I.I. Mechnikov ( Site 1709) Suspended Dnipropetrovsk Dnipropetrovska Oblast 49005 Ukraine Details
Clinical oncology dispensary of Dnipro ( Site 1706) Completed Dnipro Dnipropetrovska Oblast 49055 Ukraine Details
Municipal Non-Profit Enterprise City Clinical Hospital 4 of Dnipro City Council ( Site 1705) Suspended Dnipro Dnipropetrovska Oblast 49102 Ukraine Details
Ukrainian Center of Tomotherapy ( Site 1708) Suspended Kropyvnitskiy Kirovohradska Oblast 25011 Ukraine Details
PP PPC Acinus Medical and Diagnostic Centre ( Site 1704) Suspended Kropyvnytskyi Kirovohradska Oblast 25006 Ukraine Details
Medical Center of Yuriy Spizhenko LLC.-Clinical Trial ( Site 1703) Suspended Kapitanivka Village Kyivska Oblast 08111 Ukraine Details
National Cancer Institute of the MoH of Ukraine ( Site 1702) Suspended Kyiv Kyivska Oblast 03022 Ukraine Details
LISOD. Hospital ( Site 1707) Suspended Pliuty Kyiv 08720 Ukraine Details
Kyiv City Clinical Oncology Centre ( Site 1701) Suspended Kyiv 03115 Ukraine Details
Weston Park Hospital ( Site 1607) Active, not recruiting Sheffield England S10 2SJ United Kingdom Details
Castle Hill Hospital ( Site 1601) Recruiting Cottingham-Hull Kingston Upon Hull HU16 5JQ United Kingdom Details
Guy s & St Thomas NHS Foundation Trust ( Site 1604) Recruiting London London, City Of SE1 9RT United Kingdom Details
Royal Marsden Hospital - Fulham Road London ( Site 1609) Recruiting London London, City Of SW3 6JJ United Kingdom Details
Imperial Healthcare NHS Trust Charing Cross Hospital ( Site 1603) Recruiting London London, City Of W6 8RF United Kingdom Details
*Shaded cells indicate that there was no data available from for the field