Clinical Trial Detail


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NCT ID NCT03864042
Title Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors
Recruitment Recruiting
Gender both
Phase Phase I
Variant Requirements Yes
Sponsors Array BioPharma


skin melanoma

Advanced Solid Tumor


Caffeine + Dextromethorphan + Losartan + Midazolam + Omeprazole


Bupropion + Rosuvastatin

Binimetinib + Encorafenib

Age Groups: senior | adult
Covered Countries USA | ESP | CAN | BEL

Facility Status City State Zip Country Details
UC Irvine Health Active, not recruiting Orange California 92868-3201 United States Details
University of Colorado Hospital - Anschutz Cancer Pavilion (ACP) Recruiting Aurora Colorado 80045 United States Details
University of Illinois at Chicago Active, not recruiting Chicago Illinois 60612 United States Details
Regions Cancer Care Center Recruiting Saint Paul Minnesota 55101 United States Details
HealthPartners Specialty Center-Eye Care Recruiting Saint Paul Minnesota 55130 United States Details
Nebraska Methodist Hospital Not yet recruiting Omaha Nebraska 68114 United States Details
Gabrail Cancer Center Research Recruiting Canton Ohio 44718 United States Details
University of TN Medical Center Recruiting Knoxville Tennessee 37920 United States Details
Mary Crowley Cancer Research Centers - Medical City Hospital Recruiting Dallas Texas 75230 United States Details
Utah Cancer Specialists Recruiting Salt Lake City Utah 84106 United States Details
UZ Antwerpen Pharmacy Recruiting Edegem Antwerpen 2650 Belgium Details
AZ Sint-Maarten Not yet recruiting Mechelen Antwerpen 02800 Belgium Details
CHU de Liège Not yet recruiting Liège 4000 Belgium Details
AZ Sint-Maarten Not yet recruiting Mechelen 02800 Belgium Details
Cross Cancer Institute Not yet recruiting Edmonton Alberta T6G 1Z2 Canada Details
Princess Margaret Cancer Centre Recruiting Toronto Ontario M5G 2M9 Canada Details
McGill University Health Center Recruiting Montreal Quebec H4A 3J1 Canada Details
Jewish General Hospital Recruiting Montrea Quebec H3T 1E2 Canada Details
Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis Recruiting Amsterdam 1066 CX Netherlands Details
Erasmus Medical Center Not yet recruiting Rotterdam 3000 CA Netherlands Details
University Medical Center Utrecht Not yet recruiting Utrecht 3584 CX Netherlands Details
Hospital del Mar Recruiting Barcelona 08003 Spain Details
Hospital Clinico Universitario Virgen de la Arrixaca Recruiting El Palmar 30120 Spain Details
Hospital Universitari Arnau de Vilanova Recruiting Lleida 25198 Spain Details
Hospital Beata Maria Ana Recruiting Madrid 28007 Spain Details
Hospital General Universitario Gregorio Marañon Recruiting Madrid 28007 Spain Details
Clinica Rementeria Recruiting Madrid 28010 Spain Details
MD Anderson Cancer Center Madrid Recruiting Madrid 28033 Spain Details
Hospital Universitario HM Sanchinarro - CIOCC Recruiting Madrid 28050 Spain Details
CERCO Recruiting Sevilla 41009 Spain Details
Hospital Universitario Virgen Macarena Recruiting Sevilla 41009 Spain Details
*Shaded cells indicate that there was no data available from for the field