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| NCT ID | NCT03864042 |
| Title | Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | Yes |
| Sponsors | Array BioPharma |
| Indications | |
| Therapies |
Caffeine + Dextromethorphan + Losartan + Midazolam + Omeprazole |
| Age Groups: | senior | adult |
| Covered Countries | USA | ESP | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UC Irvine Health | Active, not recruiting | Orange | California | 92868-3201 | United States | Details |
| University of Colorado Hospital - Anschutz Cancer Pavilion (ACP) | Recruiting | Aurora | Colorado | 80045 | United States | Details |
| University of Illinois at Chicago | Active, not recruiting | Chicago | Illinois | 60612 | United States | Details |
| Regions Cancer Care Center | Recruiting | Saint Paul | Minnesota | 55101 | United States | Details |
| HealthPartners Specialty Center-Eye Care | Recruiting | Saint Paul | Minnesota | 55130 | United States | Details |
| Nebraska Methodist Hospital | Not yet recruiting | Omaha | Nebraska | 68114 | United States | Details |
| Gabrail Cancer Center Research | Recruiting | Canton | Ohio | 44718 | United States | Details |
| University of TN Medical Center | Recruiting | Knoxville | Tennessee | 37920 | United States | Details |
| Mary Crowley Cancer Research Centers - Medical City Hospital | Recruiting | Dallas | Texas | 75230 | United States | Details |
| Utah Cancer Specialists | Recruiting | Salt Lake City | Utah | 84106 | United States | Details |
| UZ Antwerpen Pharmacy | Recruiting | Edegem | Antwerpen | 2650 | Belgium | Details |
| AZ Sint-Maarten | Not yet recruiting | Mechelen | Antwerpen | 02800 | Belgium | Details |
| CHU de Liège | Not yet recruiting | Liège | 4000 | Belgium | Details | |
| AZ Sint-Maarten | Not yet recruiting | Mechelen | 02800 | Belgium | Details | |
| Cross Cancer Institute | Not yet recruiting | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| Princess Margaret Cancer Centre | Recruiting | Toronto | Ontario | M5G 2M9 | Canada | Details |
| McGill University Health Center | Recruiting | Montreal | Quebec | H4A 3J1 | Canada | Details |
| Jewish General Hospital | Recruiting | Montrea | Quebec | H3T 1E2 | Canada | Details |
| Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis | Recruiting | Amsterdam | 1066 CX | Netherlands | Details | |
| Erasmus Medical Center | Not yet recruiting | Rotterdam | 3000 CA | Netherlands | Details | |
| University Medical Center Utrecht | Not yet recruiting | Utrecht | 3584 CX | Netherlands | Details | |
| Hospital del Mar | Recruiting | Barcelona | 08003 | Spain | Details | |
| Hospital Clinico Universitario Virgen de la Arrixaca | Recruiting | El Palmar | 30120 | Spain | Details | |
| Hospital Universitari Arnau de Vilanova | Recruiting | Lleida | 25198 | Spain | Details | |
| Hospital Beata Maria Ana | Recruiting | Madrid | 28007 | Spain | Details | |
| Hospital General Universitario Gregorio Marañon | Recruiting | Madrid | 28007 | Spain | Details | |
| Clinica Rementeria | Recruiting | Madrid | 28010 | Spain | Details | |
| MD Anderson Cancer Center Madrid | Recruiting | Madrid | 28033 | Spain | Details | |
| Hospital Universitario HM Sanchinarro - CIOCC | Recruiting | Madrid | 28050 | Spain | Details | |
| CERCO | Recruiting | Sevilla | 41009 | Spain | Details | |
| Hospital Universitario Virgen Macarena | Recruiting | Sevilla | 41009 | Spain | Details |