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NCT ID NCT03869190
Title A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-based Treatment Combinations in Patients With Locally Advanced or Metastatic Urothelial Carcinoma After Failure With Platinum-Containing Chemotherapy (MORPHEUS mUC)
Recruitment Recruiting
Gender both
Phase Phase Ib/II
Variant Requirements No
Sponsors Hoffmann-La Roche
Indications

ureter transitional cell carcinoma

bladder urothelial carcinoma

renal pelvis transitional cell carcinoma

urethra transitional cell carcinoma

Therapies

Atezolizumab + Tocilizumab

Atezolizumab + Niraparib

Atezolizumab + Hu5F9-G4

Atezolizumab + Enfortumab vedotin-ejfv

Atezolizumab + Linagliptin

Atezolizumab + Isatuximab

Atezolizumab

Age Groups: adult | senior
Covered Countries USA | FRA | ESP

Facility Status City State Zip Country Details
UCLA Department of Medicine Recruiting Los Angeles California 90024 United States Details
UCSF Comprehensive Cancer Ctr Recruiting San Francisco California 94158 United States Details
Stanford Cancer Center Recruiting Stanford California 94305-5820 United States Details
University of Kentucky Chandler Medical Center Recruiting Lexington Kentucky 40536 United States Details
Norton Cancer Institute Recruiting Louisville Kentucky 40202 United States Details
Levine Cancer Institute Recruiting Charlotte North Carolina 28204 United States Details
Cleveland Clinic Recruiting Cleveland Ohio 44195 United States Details
Centre Francois Baclesse; Pharmacie Recruiting Caen 14076 France Details
Centre Leon Berard Recruiting Lyon 69008 France Details
Institut régional du Cancer Montpellier Recruiting Montpellier 34298 France Details
Institut Claudius Regaud; Radiotherapie Recruiting Toulouse 31052 France Details
Gustave Roussy Cancer Campus Completed Villejuif 94805 France Details
Alexandras General Hospital of Athens; Oncology Department Completed Athens 115 28 Greece Details
Attiko Hospital University of Athens; 2Nd Dept. of Propaedeutic Medicine Recruiting Athens 12462 Greece Details
Athens Medical Center; Dept. of Oncology Recruiting Athens 151 25 Greece Details
University Hospital of Patras Medical Oncology Withdrawn Patras 265 04 Greece Details
Seoul National University Hospital Recruiting Seoul 03080 Korea, Republic of Details
Asan Medical Center Recruiting Seoul 05505 Korea, Republic of Details
Severance Hospital; Yonsei Cancer Center; Yonsei University College of Medicine Recruiting Seoul 120-749 Korea, Republic of Details
ICO I Hospitalet Hospital Duran i Reynals Instituto Catalan de Oncologia de Hospitalet ICO Recruiting L'Hospitalet de Llobregat Barcelona 08908 Spain Details
Complejo Hospitalario Universitario de Santiago (CHUS) ; Intermedios y Urgencias Pediatricas Recruiting Santiago de Compostela LA Coruña 15706 Spain Details
Clinica Universitaria de Navarra Completed Pamplona Navarra 31008 Spain Details
Hospital del Mar Recruiting Barcelona 08003 Spain Details
Vall d´Hebron Institute of Oncology (VHIO), Barcelona Recruiting Barcelona 08035 Spain Details
Hospital Clinic i Provincial; Servicio de Neurologia Recruiting Barcelona 08036 Spain Details
Hospital Universitario Reina Sofia Recruiting Cordoba 14008 Spain Details
Hospital General Universitario Gregorio Mara Recruiting Madrid 28009 Spain Details
MD Anderson Cancer Center Recruiting Madrid 28033 Spain Details
Hospital Universitario Fundacion Jimenez Diaz. Recruiting Madrid 28040 Spain Details
Hospital Univ 12 de Octubre Recruiting Madrid 28041 Spain Details
START Madrid. Centro Integral Oncologico Clara Campal; CIOCC Recruiting Madrid 28050 Spain Details
Hospital Clinico Universitario de Valencia Recruiting Valencia 46010 Spain Details
Kaohsiung Medical University Chung-Ho Memorial Hospital Recruiting Kaohsiung City 807 Taiwan Details
National Cheng Kung University Hospital Recruiting Tainan 70457 Taiwan Details
Barts and The London Recruiting London EC1M 6BQ United Kingdom Details
The Christie NHS Foundation Trust Withdrawn Manchester M20 4BX United Kingdom Details
Churchill Hospital; Pharmacy Clinical Trials Office, Pharmacy Department Recruiting Oxford OX3 7LJ United Kingdom Details
Royal Marsden NHS Foundation Trust Recruiting Sutton SM2 5PT United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field