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| NCT ID | NCT03875079 |
| Title | A Phase IB Study To Evaluate Safety And Therapeutic Activity Of RO6874281, An Immunocytokine, Consisting Of Interleukin-2 Variant Targeting Fibroblast Activation Protein-A, In Combination With Pembrolizumab (Anti-Pd-1), In Participants With Previously Untreated Advanced And/Or Metastatic Melanoma |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | FRA | ESP | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Yale University | New Haven | Connecticut | 06510 | United States | Details | |
| University of Iowa | Iowa City | Iowa | 52242 | United States | Details | |
| Beth Israel Deaconess Med Ctr | Boston | Massachusetts | 02215 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Melanoma Institute Australia | North Sydney | New South Wales | 2060 | Australia | Details | |
| Peter Maccallum Cancer Institute; Clinical Trial Unit | Melbourne | Victoria | 3000 | Australia | Details | |
| UZ Antwerpen | Edegem | 2650 | Belgium | Details | ||
| UZ Leuven Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 1Z5 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Hopital Claude Huriez; Sce Dermatologie | Lille | 59037 | France | Details | ||
| Hôpital de la Timone; Dermatologie | Marseille | 13005 | France | Details | ||
| Centre Eugene Marquis; Service d'oncologie | Rennes | 35042 | France | Details | ||
| Institut Gustave Roussy; Dermatologie | Villejuif | 94805 | France | Details | ||
| Main Military Clinical Hospital named after N.N. Burdenko | Moscow | Moskovskaja Oblast | 105229 | Russian Federation | Details | |
| Russian Oncology Research Center n.a. N.N. Blokhin | Moscow | 115478 | Russian Federation | Details | ||
| P.A. Gertsen Cancer Research Inst. ; Chemotherapy Dept | Moscow | 125284 | Russian Federation | Details | ||
| FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov" | Saint-Petersburg | Russian Federation | Details | |||
| Clinica Universitaria de Navarra; Servicio de Oncologia | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Universitari Vall d'Hebron; Oncology | Barcelona | 08035 | Spain | Details | ||
| Hospital Clínic i Provincial; Servicio de Oncología | Barcelona | 08036 | Spain | Details | ||
| Clinica Universidad de Navarra Madrid; Servicio de Oncología | Madrid | 28027 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details |