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NCT ID NCT03906071
Title Phase 3 Study of Sitravatinib Plus Nivolumab vs Docetaxel in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer (SAPPHIRE)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Mirati Therapeutics Inc.
Indications

lung non-squamous non-small cell carcinoma

Therapies

Docetaxel

MGCD516 + Nivolumab

Age Groups: adult | senior
Covered Countries USA | CAN

Facility Status City State Zip Country Details
Alabama Oncology - Grandview Recruiting Birmingham Alabama 35243 United States Details
Clearview Cancer Institute Recruiting Huntsville Alabama 35805 United States Details
Palo Verde Cancer Specialists - Glendale Recruiting Glendale Arizona 85304 United States Details
The Oncology Institute of Hope and Innovation - Tucson Recruiting Tucson Arizona 85745 United States Details
Yuma Regional Medical Center Recruiting Yuma Arizona 85364 United States Details
NEA Baptist Fowler Family Center for Cancer Care Recruiting Jonesboro Arkansas 72401 United States Details
Saint Bernards Medical Center Recruiting Jonesboro Arkansas 72401 United States Details
Highlands Oncology Group - Springdale Recruiting Springdale Arkansas 72762 United States Details
Comprehensive Blood and Cancer Center - Bakersfield Recruiting Bakersfield California 93309 United States Details
Beverly Hills Cancer Center Recruiting Beverly Hills California 90211 United States Details
The Oncology Institute of Hope and Innovation - Corona Recruiting Corona California 92882 United States Details
Saint Joseph Heritage Healthcare - Virginia K. Crosson Cancer Center Recruiting Fullerton California 92835 United States Details
Pacific Shores Medical Group Recruiting Long Beach California 90813 United States Details
Cancer and Blood Specialty Clinic Recruiting Los Alamitos California 90720 United States Details
Los Angeles Hematology Oncology Medical Group Recruiting Los Angeles California 90017 United States Details
University of California Los Angeles - Jonsson Comprehensive Cancer Center Recruiting Los Angeles California 90024 United States Details
Hoag Memorial Hospital Presbyterian Recruiting Newport Beach California 92663 United States Details
Redlands Hematology Oncology Recruiting Redlands California 92373 United States Details
University of California San Francisco Recruiting San Francisco California 94518 United States Details
California Cancer Associates for Research and Excellence - San Marcos Terminated San Marcos California 92069 United States Details
The Oncology Institute of Hope and Innovation - Thousand Oaks Recruiting Thousand Oaks California 91361 United States Details
Torrance Memorial Physician Network - Cancer Care and Infusion Center Recruiting Torrance California 90505 United States Details
Brian J. LeBerthon M.D. Recruiting West Covina California 91790 United States Details
The Oncology Institute of Hope and Innovation - Whittier Recruiting Whittier California 90603 United States Details
Sisters of Charity of Leavenworth Health St. Mary's Recruiting Grand Junction Colorado 81501 United States Details
Good Samaritan Medical Center Recruiting Lafayette Colorado 80026 United States Details
Eastern Connecticut Hematology and Oncology Associates Recruiting Norwich Connecticut 06360 United States Details
Michael and Dianne Bienes Comprehensive Cancer Center Recruiting Fort Lauderdale Florida 33308 United States Details
Florida Cancer Specialists & Research Institute Recruiting Fort Myers Florida 33901 United States Details
Memorial Regional Hospital Recruiting Hollywood Florida 33021 United States Details
Watson Clinic Cancer & Research Center Recruiting Lakeland Florida 33805 United States Details
Mount Sinai Medical Center Recruiting Miami Beach Florida 33140 United States Details
Florida Cancer Affiliates - Ocala - Main Recruiting Ocala Florida 34474 United States Details
Cancer Institute of Florida - Orlando Recruiting Orlando Florida 32804 United States Details
BRCR Medical Center Inc Recruiting Plantation Florida 33322 United States Details
SCRI - Florida Cancer Specialists - North Region Research Office Recruiting Sarasota Florida 34232 United States Details
SCRI - Florida Cancer Specialists - Panhandle Research Office Recruiting Tallahassee Florida 32308 United States Details
SCRI - Florida Cancer Specialists - West Palm Beach Recruiting West Palm Beach Florida 33401 United States Details
University Cancer and Blood Center - LLC - Athens Recruiting Athens Georgia 30607 United States Details
Piedmont Cancer Institute Recruiting Atlanta Georgia 30318 United States Details
John B. Amos Cancer Center Research Recruiting Columbus Georgia 31904 United States Details
Northwest Georgia Oncology Centers - Marietta Recruiting Marietta Georgia 30060 United States Details
Straub Medical Center Recruiting Honolulu Hawaii 96813 United States Details
Beacon Cancer Care Recruiting Coeur d'Alene Idaho 83814 United States Details
Swedish Covenant Hospital Recruiting Chicago Illinois 60625 United States Details
Evanston Hospital Recruiting Evanston Illinois 60201 United States Details
Illinois Cancer Specialists - Niles Recruiting Niles Illinois 60714 United States Details
Orchard Healthcare Research Inc. Recruiting Skokie Illinois 60077 United States Details
Fort Wayne Medical Oncology and Hematology - Fort Wayne South Office Recruiting Fort Wayne Indiana 46804 United States Details
Goshen Center for Cancer Care Recruiting Goshen Indiana 46526 United States Details
Franciscan Health Indianapolis Recruiting Indianapolis Indiana 46237 United States Details
Indiana University Health Arnett Cancer Care Recruiting Lafayette Indiana 47904 United States Details
The Richard and Annette Bloch Cancer Care Pavilion and Westwood Medical Pavilion Recruiting Westwood Kansas 66205 United States Details
Cancer Center of Kansas Recruiting Wichita Kansas 67214 United States Details
Commonwealth Cancer Center Recruiting Danville Kentucky 40422 United States Details
Norton Cancer Institute - Broadway Recruiting Louisville Kentucky 40241 United States Details
Pontchartrain Cancer Center - Covington Office Recruiting Covington Louisiana 70433 United States Details
New England Cancer Specialists Recruiting Scarborough Maine 04074 United States Details
Maryland Oncology Hematology - Rockville Aquilino Cancer Center Recruiting Rockville Maryland 20850 United States Details
Barbara Ann Karmanos Cancer Institute Recruiting Detroit Michigan 48201 United States Details
Henry Ford Hospital Recruiting Detroit Michigan 48202 United States Details
Minnesota Oncology - Minneapolis Clinic Withdrawn Coon Rapids Minnesota 55433 United States Details
Park Nicollet - Frauenshuh Cancer Center Recruiting Saint Louis Park Minnesota 55426 United States Details
Jackson Oncology Associates Recruiting Jackson Mississippi 39202 United States Details
Central Care Cancer Center - Bolivar Recruiting Bolivar Missouri 65613 United States Details
Kansas City Care Health Center - Research Medical Campus Terminated Kansas City Missouri 64132 United States Details
St. Vincent Frontier Cancer Center Recruiting Billings Montana 59102 United States Details
Methodist Hospital - Omaha Recruiting Omaha Nebraska 68114 United States Details
Comprehensive Cancer Centers of Nevada Recruiting Henderson Nevada 89074 United States Details
Summit Medical Group - Florham Park Campus Recruiting Florham Park New Jersey 07932 United States Details
Regional Cancer Care Associates - Little Silver Recruiting Little Silver New Jersey 07739 United States Details
Saint Barnabas Medical Center Recruiting Livingston New Jersey 07039 United States Details
Broome Oncology Recruiting Johnson City New York 13790 United States Details
Monter Cancer Center Recruiting Lake Success New York 11042 United States Details
New York Cancer & Blood Specialists Recruiting Port Jefferson Station New York 11776 United States Details
Stony Brook University Cancer Center Recruiting Stony Brook New York 11794 United States Details
Mercy Hematology & Oncology Associates Recruiting Canton Ohio 44708 United States Details
Oncology Hematology Care - Blue Ash Recruiting Cincinnati Ohio 45242 United States Details
The Ohio State University College of Medicine Recruiting Columbus Ohio 43210 United States Details
Tricounty Hematology and Oncology- Massillon Recruiting Massillon Ohio 44646 United States Details
Toledo Clinic Cancer Center Recruiting Toledo Ohio 43623 United States Details
Mercy Clinic Oncology and Hematology - Coletta Recruiting Oklahoma City Oklahoma 73120 United States Details
Providence Cancer Institute Franz Clinic Recruiting Portland Oregon 97213 United States Details
Oregon Health and Science University Knight Cancer Institute Recruiting Portland Oregon 97239 United States Details
USOR - Consultants in Medical Oncology and Hematology PC - Abington Hematology/Oncology Associates Recruiting Horsham Pennsylvania 19044 United States Details
Fox Chase Cancer Center Recruiting Philadelphia Pennsylvania 19111 United States Details
Baptist Cancer Center - Memphis Recruiting Memphis Tennessee 38120 United States Details
SCRI - Tennessee Oncology - Nashville - Centennial Recruiting Nashville Tennessee 37203 United States Details
Texas Oncology - South Austin Recruiting Austin Texas 78745 United States Details
Texas Oncology - Beaumont Mamie Mcfaddin Ward Cancer Center Recruiting Beaumont Texas 77702 United States Details
Texas Oncology - Methodist Dallas Cancer Center Recruiting Dallas Texas 75203 United States Details
Texas Oncology - Dallas Presbyterian Hospital Recruiting Dallas Texas 75231 United States Details
Texas Oncology - Baylor Charles A. Sammons Cancer Center Recruiting Dallas Texas 75246 United States Details
Texas Oncology - Denton South Recruiting Denton Texas 76210 United States Details
The Center for Cancer & Blood Disorders - Fort Worth Recruiting Fort Worth Texas 76104 United States Details
Texas Oncology - Houston Willowbrook Recruiting Houston Texas 77070 United States Details
Millennium Physicians - North Houston Recruiting Houston Texas 77090 United States Details
Texas Oncology - McKinney Recruiting McKinney Texas 75071 United States Details
Texas Oncology - San Antonio Recruiting San Antonio Texas 78240 United States Details
Texas Oncology - Sherman Recruiting Sherman Texas 75090 United States Details
Texas Oncology - Sugar Land Recruiting Sugar Land Texas 77479 United States Details
Texas Oncology - Tyler Recruiting Tyler Texas 75702 United States Details
University of Virginia Cancer Center Recruiting Charlottesville Virginia 22908 United States Details
Hematology Oncology Associates of Fredericksburg Recruiting Fredericksburg Virginia 22408 United States Details
Virginia Cancer Institute - Reynolds Crossing Recruiting Richmond Virginia 23230 United States Details
Providence Regional Center Partnership Recruiting Everett Washington 98201 United States Details
Seattle Cancer Care Alliance Recruiting Seattle Washington 98109 United States Details
Cancer Care Northwest - North Spokane Recruiting Spokane Washington 99216 United States Details
MultiCare Institute for Research & Innovation Recruiting Tacoma Washington 98405 United States Details
Northwest Medical Specialties, PLLC Recruiting Tacoma Washington 98405 United States Details
Northwest Cancer Specialists Recruiting Vancouver Washington 98684 United States Details
ThedaCare Regional Cancer Center Recruiting Appleton Wisconsin 54911 United States Details
University Wisconsin Carbone Cancer Center Recruiting Madison Wisconsin 53705 United States Details
Froedtert Hospital - Medical College of Wisconsin Recruiting Milwaukee Wisconsin 53226 United States Details
Algemeen Ziekenhuis Klina Recruiting Brasschaat Antwerp 2930 Belgium Details
Algemeen Ziekenhuis Glorieux Ronse Recruiting Ronse East Flanders 9600 Belgium Details
Grand Hôpital de Charleroi - Notre Dame Recruiting Charleroi Henegouwen 6000 Belgium Details
Centre Hospitalier Universitaire Universite Catholique de Louvain - Site Godinne Recruiting Yvoir Namur B-5530 Belgium Details
Algemeen Ziekenhuis Maria Middelares Recruiting Gent Oost-Vlaaderen 9000 Belgium Details
Algemeen Ziekenhuis Delta Recruiting Roeselare West-Vlaanderen 8800 Belgium Details
Universitair Ziekenhuis Gent Recruiting Gent 9000 Belgium Details
Horizon Health Network - The Moncton Hospital Recruiting Moncton New Brunswick E1C 6Z8 Canada Details
Saint John Regional Hospital Recruiting Saint John New Brunswick E2L 4L2 Canada Details
Juravinski Cancer Centre Recruiting Hamilton Ontario L8V 5C2 Canada Details
Princess Margaret Cancer Centre Recruiting Toronto Ontario M5G 2M9 Canada Details
Windsor Regional Hospital Cancer Program Recruiting Windsor Ontario N8W 3X3 Canada Details
Institut Universitaire de Cardiologie et de Pneumologie de Québec-Universite Laval Recruiting Québec G1V 4G5 Canada Details
Saskatoon Cancer Center Recruiting Saskatoon S7N 4H4 Canada Details
Hôpital Morvan Recruiting Brest 29200 France Details
Hôpital Louis Pradel Recruiting Bron 69677 France Details
Centre Hospitalier Intercommunal de Créteil Recruiting Créteil 94010 France Details
Centre Georges François Leclerc Recruiting Dijon Cedex 21079 France Details
Centre Hospitalier Le Mans Recruiting Le Mans Cedex 9 72037 France Details
Centre Hospitalier Universitaire Limoges Recruiting Limoges Cedex 87042 France Details
Hôpital Nord de Marseille Recruiting Marseille cedex 20 13915 France Details
Institut Paoli-Calmettes Recruiting Marseille 13009 France Details
Hôpital Bichat-Claude-Bernard Recruiting Paris Cedex 18 75877 France Details
Rouen University Hôpital Charles-Nicolle Recruiting Rouen 76031 France Details
Centre Hospitalier Universitaire De Nantes - Hôpital Nord Laennec Recruiting Saint-Herblain 44800 France Details
Institut de Cancérologie Strasbourg Europe Recruiting Strasbourg 67200 France Details
Institut Gustave Roussy Recruiting Villejuif Cedex 94802 France Details
Klinik Löwenstein gGmbH Recruiting Heilbronn Baden-Württemberg 74078 Germany Details
Klinikverbund Kempten-Oberallgäu - Klinik Immenstadt - Klinikverbund Allgäu gGmbH Recruiting Immenstadt Bayern 87509 Germany Details
LungenClinic Grosshansdorf GmbH Recruiting Großhansdorf Schleswig-Holstein 22927 Germany Details
Evangelische Lungenklinik Berlin Recruiting Berlin 13125 Germany Details
Universitätsklinikum Bonn Recruiting Bonn 53127 Germany Details
Asklepios Fachkliniken München-Gauting Recruiting Gauting 82131 Germany Details
Martha-Maria Krankenhaus Halle-Dölau gGmbH, Studiensekretariat Recruiting Halle 06120 Germany Details
Klinikum Kassel Recruiting Kassel 34125 Germany Details
Universitatsklinikum Schleswig-Holstein-Campus Lubeck Recruiting Lübeck 23538 Germany Details
Universitätsmedizin der Johannes Gutenberg-Universität Mainz - III. Medizinischen Klinik und Poliklinik Recruiting Mainz 55131 Germany Details
Klinikum rechts der Isar der Technischen Universität München Recruiting München 81675 Germany Details
Munchen Klinik Bogenhausen Recruiting München 81925 Germany Details
Petz Aladár Megyei Oktató Kórház Recruiting Győr Gyor-Moson-Sopron 9024 Hungary Details
Szent Borbála Kórház Recruiting Tatabánya Komárom-Esztergom 2800 Hungary Details
Intézeti Gyógyszertár Recruiting Szombathely Vas 9700 Hungary Details
Semmelweis Egyetem - Pulmonológiai Klinika Recruiting Budapest 1083 Hungary Details
Országos Korányi Tbc És Pulmonológiai Intézet Recruiting Budapest 1121 Hungary Details
Országos Onkológiai Intézet Recruiting Budapest 1122 Hungary Details
Veszprém Megyei Tüdőgyógyintézet Recruiting Farkasgyepű 8582 Hungary Details
Törökbálinti Tüdőgyógyintézet Recruiting Törökbálint 2045 Hungary Details
Emek Medical Center Recruiting Afula 1834111 Israel Details
Soroka Medical Center Recruiting Be'er Sheva 8410101 Israel Details
Shamir Medical Center (Assaf Harofeh) Recruiting Be'er Ya'aqov 7030000 Israel Details
Shaare Zedek Medical Center Recruiting Jerusalem 9103102 Israel Details
Chaim Sheba Medical Center Recruiting Ramat Gan 5265601 Israel Details
Ziv Medical Center Recruiting Safed 1311001 Israel Details
The Edith Wolfson Medical Center Recruiting Tel Aviv 5822012 Israel Details
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Recruiting Meldola Forlì-Cesena 47014 Italy Details
Istituto Europeo di Oncologia Recruiting Milano Lombardia 20141 Italy Details
Istituto Nazionale Tumori IRCCS Fondazione G. Pascale Recruiting Napoli Naples 80100 Italy Details
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo Recruiting Alessandria 15121 Italy Details
IRCCS Istituto Tumori "Giovanni Paolo II" Recruiting Bari 70124 Italy Details
Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco" Recruiting Catania 95123 Italy Details
Ospedale di Cremona Recruiting Cremona 26100 Italy Details
ASL Lecce - Ospedale Vito Fazzi Recruiting Lecce 73100 Italy Details
S.C Oncologia Medica, ASST Monza - Ospedale San Gerardo Recruiting Monza 20900 Italy Details
Ospedale Guglielmo da Saliceto Recruiting Piacenza 29121 Italy Details
Azienda Ospedaliero - Universitaria Pisana Recruiting Pisa 56126 Italy Details
Istituto Nazionale Tumori Regina Elena Recruiting Roma 00144 Italy Details
ASST-SETTE LAGHI, Ospedale di Circolo e Fondazione Macchi Recruiting Varese 21100 Italy Details
Maastricht Universitair Medisch Centrum Recruiting Maastricht Limburg 6229 HX Netherlands Details
The Netherlands Cancer Institute Recruiting Amsterdam Noord-Holland 1066 CX Netherlands Details
Jeroen Bosch Ziekenhuis Recruiting s-Hertogenbosch North Brabant 5223 GZ Netherlands Details
Isala Recruiting Zwolle Overijssel 8025 BK Netherlands Details
Franciscus Vlietland & Gasthuis Recruiting Schiedam South Holland 3118 JH Netherlands Details
Ziekenhuis Nieuwegein Recruiting Nieuwegein Utrecht 3435 CM Netherlands Details
Hagaziekenhuis Van Den Haag - Leyweg Recruiting Den Haag Zuid-Holland 2545 AA Netherlands Details
Erasmus Medisch Centrum Recruiting Rotterdam Zuid-Holland 3015 GD Netherlands Details
Amsterdam Universitair Medische Centra - Vrije Universiteit Medisch Centrum Recruiting Amsterdam 1081 HV Netherlands Details
Amphia Ziekenhuis - Breda Molengracht Recruiting Breda 4818 CK Netherlands Details
Albert Schweitzer Ziekenhuis Recruiting Dordrecht 3318 AT Netherlands Details
Martini Ziekenhuis Recruiting Groningen 9700 RM Netherlands Details
UMC Utrecht Recruiting Utrecht 3584 CX Netherlands Details
Institut Català d'Oncologia Badalona, Hospital Universitari Germans Trias i Puj Recruiting Badalona Barcelona 8916 Spain Details
Complejo Hospitalario Universitario A Coruña Recruiting A Coruña La Coruña 15006 Spain Details
Hospital Universitario Puerta de Hierro - Majadahonda Recruiting Majadahonda Madrid 28222 Spain Details
Hospital Regional Universitario de Málaga - Hospital Civil Recruiting Málaga Malaga 29010 Spain Details
Hospital Universitari Dexeus Recruiting Barcelona 08028 Spain Details
Hospital Universitario Vall d'Hebron Recruiting Barcelona 08035 Spain Details
Complejo Hospitalario de Jaén Recruiting Jaén 23007 Spain Details
Hospital Universitario Insular de Gran Canaria Recruiting Las Palmas De Gran Canaria 35016 Spain Details
Hospital de León Recruiting León 24071 Spain Details
Hospital Universitario Lucus Augusti Recruiting Lugo 27003 Spain Details
Complejo Hospitalario Ruber Juan Bravo Recruiting Madrid 28006 Spain Details
Hospital Universitario La Princesa Recruiting Madrid 28006 Spain Details
Clinica Universidad de Navarra - Madrid Recruiting Madrid 28027 Spain Details
Hospital Universitario Ramón y Cajal Recruiting Madrid 28034 Spain Details
Hospital Clinico San Carlos Recruiting Madrid 28040 Spain Details
Hospital Universitario Fundación Jiménez Díaz Recruiting Madrid 28040 Spain Details
Hospital Universitario 12 de Octubre Recruiting Madrid 28041 Spain Details
Hospital Universitario La Paz Recruiting Madrid 28046 Spain Details
Hospital Universitario Central de Asturias Recruiting Oviedo 15006 Spain Details
Hospital Universitari i Politècnic La Fe Recruiting Valencia 46026 Spain Details
Hospital Alvaro Cunqueiro - Clinico Universitario Vigo Recruiting Vigo 36312 Spain Details
Inselspital Universitätsspital Bern Recruiting Bern CH-3010 Switzerland Details
HUG: hopitaux universitaires de genève Recruiting Genève CH - 1211 Switzerland Details
Centre Hospitalier Universitaire Vaudois Recruiting Lausanne CH-1011 Switzerland Details
Kantonsspital Winterthur Recruiting Winterthur CH-8401 Switzerland Details
Royal Cornwall Hospital NHS Trust Recruiting Truro Cornwall TR1 3LI United Kingdom Details
The Christie NHS Foundation Trust Recruiting Withington Manchester M20 4BX United Kingdom Details
East and North Hertfordshire NHS Trust Recruiting Northwood Middlesex HA6 2RN United Kingdom Details
Velindre University NHS Trust Not yet recruiting Cardiff CF14 2TL United Kingdom Details
University Hospitals of Leicester NHS Trust Recruiting Leicester LE1 5WW United Kingdom Details
Barts Health NHS Trust Recruiting London EC1A 7BE United Kingdom Details
Royal Free London NHS Foundation Trust Recruiting London NW3 2QG United Kingdom Details
The Royal Marsden NHS Foundation Trust Recruiting London SW3 6JJ United Kingdom Details
The Royal Marsden NHS Foundation Trust Recruiting Sutton SM2 5PT United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field