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| NCT ID | NCT03952039 |
| Title | An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib (FREEDOM2) |
| Acronym | FREEDOM2 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Celgene |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | NLD | ITA | GBR | FRA | ESP | DEU | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Local Institution - 103 | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| Local Institution - 101 | Adelaide | South Australia | 5000 | Australia | Details | |
| Local Institution - 105 | Box Hill | Victoria | 3128 | Australia | Details | |
| Local Institution - 102 | Frankston | Victoria | 3199 | Australia | Details | |
| Local Institution - 100 | Melbourne | 3004 | Australia | Details | ||
| Local Institution - 156 | Graz | 73013 | Austria | Details | ||
| Local Institution - 154 | Innsbruck | 6020 | Austria | Details | ||
| Local Institution - 155 | Linz | 4020 | Austria | Details | ||
| Local Institution - 151 | Salzburg | 5020 | Austria | Details | ||
| Local Institution - 150 | Vienna | 1090 | Austria | Details | ||
| Local Institution - 153 | Wels | 4600 | Austria | Details | ||
| Local Institution - 152 | Wien | 1140 | Austria | Details | ||
| Local Institution - 200 | Brugge | 8000 | Belgium | Details | ||
| Local Institution - 202 | Bruxelles | 1200 | Belgium | Details | ||
| Local Institution - 205 | La Louvière-(Haine St-Paul) | 7100 | Belgium | Details | ||
| Local Institution - 201 | Leuven | 3000 | Belgium | Details | ||
| Local Institution - 204 | Liege | 4000 | Belgium | Details | ||
| Local Institution - 203 | Yvoir | 5530 | Belgium | Details | ||
| Local Institution - 555 | Beijing | 100044 | China | Details | ||
| Local Institution - 550 | Guangzhou, Guangdong | 510080 | China | Details | ||
| Local Institution - 553 | Tianjin | 300041 | China | Details | ||
| Local Institution - 557 | Zhengzhou | 0 | China | Details | ||
| Local Institution - 700 | Brno | 625 00 | Czechia | Details | ||
| Local Institution - 702 | Ostrava-Poruba | 708 52 | Czechia | Details | ||
| Local Institution - 701 | Prague 2 | 128 08 | Czechia | Details | ||
| Local Institution - 255 | Angers | 49033 | France | Details | ||
| Local Institution - 256 | Brest | 29200 | France | Details | ||
| Local Institution - 254 | Lens Cedex | 62307 | France | Details | ||
| Local Institution - 259 | Lille | 59037 | France | Details | ||
| Local Institution - 260 | Nice Cedex 3 | 06200 | France | Details | ||
| Local Institution - 250 | Nimes Cedex 9 | 30029 | France | Details | ||
| Local Institution - 252 | Paris | 75010 | France | Details | ||
| Local Institution - 258 | Pessac | 33604 | France | Details | ||
| Local Institution - 257 | Pierre-Benite | 69495 | France | Details | ||
| Local Institution - 261 | Poitiers Cedex | 86021 | France | Details | ||
| Local Institution - 251 | Strasbourg | 67091 | France | Details | ||
| Local Institution - 253 | Toulouse Cedex 9 | 31059 | France | Details | ||
| Local Institution - 302 | Aachen | 52074 | Germany | Details | ||
| Local Institution - 308 | Frankfurt am Main | 60590 | Germany | Details | ||
| Local Institution - 306 | Halle | 06120 | Germany | Details | ||
| Local Institution - 303 | Jena | 07747 | Germany | Details | ||
| Local Institution - 307 | Magdeburg | 39120 | Germany | Details | ||
| Local Institution - 301 | Mannheim | 68167 | Germany | Details | ||
| Local Institution - 304 | Minden | 32429 | Germany | Details | ||
| Local Institution - 305 | Ulm | 89081 | Germany | Details | ||
| Local Institution - 600 | Budapest | 1088 | Hungary | Details | ||
| Local Institution - 601 | Györ | 9024 | Hungary | Details | ||
| Local Institution - 602 | Kaposvar | 7400 | Hungary | Details | ||
| Local Institution - 604 | Nyiregyhaza | 4400 | Hungary | Details | ||
| Local Institution - 603 | Szeged | 6720 | Hungary | Details | ||
| Local Institution - 751 | Cork | T12 DFK4 | Ireland | Details | ||
| Local Institution - 752 | Dublin | Dublin 7 | Ireland | Details | ||
| Local Institution - 750 | Dublin | Dublin 8 | Ireland | Details | ||
| Local Institution - 353 | Bologna | 40138 | Italy | Details | ||
| Local Institution - 363 | Brescia | 25123 | Italy | Details | ||
| Local Institution - 354 | Catania | 95123 | Italy | Details | ||
| Local Institution - 350 | Firenze | 50134 | Italy | Details | ||
| Local Institution - 358 | Milano | 20122 | Italy | Details | ||
| Local Institution - 362 | Naples | 80131 | Italy | Details | ||
| Local Institution - 357 | Pavia | 27100 | Italy | Details | ||
| Local Institution - 356 | Roma | 00168 | Italy | Details | ||
| Local Institution - 361 | Roma | 00168 | Italy | Details | ||
| Local Institution - 359 | Roma | 00189 | Italy | Details | ||
| Local Institution - 355 | Torino | 10126 | Italy | Details | ||
| Local Institution - 360 | Udine | 33100 | Italy | Details | ||
| Local Institution - 352 | Varese | 21100 | Italy | Details | ||
| Local Institution - 364 | Verona | 37134 | Italy | Details | ||
| Local Institution - 900 | Seongnam-si | 13620 | Korea, Republic of | Details | ||
| Local Institution - 905 | Seoul | 06351 | Korea, Republic of | Details | ||
| Local Institution - 901 | Seoul | 06591 | Korea, Republic of | Details | ||
| Local Institution - 903 | Seoul | 140-887 | Korea, Republic of | Details | ||
| Local Institution - 904 | Seoul | 3080 | Korea, Republic of | Details | ||
| Local Institution - 902 | Seoul | 5505 | Korea, Republic of | Details | ||
| Local Institution - 402 | Maastricht | 6229 HX | Netherlands | Details | ||
| Local Institution - 400 | Nijmegen | 6525 GA | Netherlands | Details | ||
| Local Institution - 803 | Poznan | 61-848 | Poland | Details | ||
| Local Institution - 801 | Warszawa | 02-776 | Poland | Details | ||
| Local Institution - 802 | Wroclaw | 50-556 | Poland | Details | ||
| Local Institution - 855 | Moscow | 125167 | Russian Federation | Details | ||
| Local Institution - 851 | Moscow | 125284 | Russian Federation | Details | ||
| Local Institution - 853 | Moscow | 129301 | Russian Federation | Details | ||
| Local Institution - 857 | Novosibirsk | 630066 | Russian Federation | Details | ||
| Local Institution - 852 | Saint Petersburg | 191024 | Russian Federation | Details | ||
| Local Institution - 854 | Saint-Petersburg | 197022 | Russian Federation | Details | ||
| Local Institution - 850 | St Petersburg | 197341 | Russian Federation | Details | ||
| Local Institution - 859 | Vladikavkaz | 362002 | Russian Federation | Details | ||
| Local Institution - 451 | Alicante | 03010 | Spain | Details | ||
| Local Institution - 452 | Badalona (Barcelona) | 8916 | Spain | Details | ||
| Local Institution - 458 | Barakaldo | 48903 | Spain | Details | ||
| Local Institution - 450 | Barcelona | 08036 | Spain | Details | ||
| Local Institution - 462 | Gerona | 17007 | Spain | Details | ||
| Local Institution - 461 | Las Palmas de Gran Canaria | 35012 | Spain | Details | ||
| Local Institution - 453 | Madrid | 28034 | Spain | Details | ||
| Local Institution - 459 | Madrid | 28041 | Spain | Details | ||
| Local Institution - 457 | Malaga | 29010 | Spain | Details | ||
| Local Institution - 454 | Murcia | 30008 | Spain | Details | ||
| Local Institution - 455 | Salamanca | 37007 | Spain | Details | ||
| Local Institution - 463 | Santa Cruz de Tenerife | 38320 | Spain | Details | ||
| Local Institution - 460 | Santiago de Compostela | 15706 | Spain | Details | ||
| Local Institution - 456 | Valencia | 46010 | Spain | Details | ||
| Local Institution - 504 | Manchester | Lancashire | M20 4BX | United Kingdom | Details | |
| Local Institution - 506 | Nottingham | Nottinghamshire | NG5 1PB | United Kingdom | Details | |
| Local Institution - 502 | Birmingham | B15 2TH | United Kingdom | Details | ||
| Local Institution - 503 | Boston | PE21 9QS | United Kingdom | Details | ||
| Local Institution - 501 | London | SE1 9RT | United Kingdom | Details | ||
| Local Institution - 505 | London | W12 0HS | United Kingdom | Details | ||
| Local Institution - 500 | Oxford | 0X3 7LE | United Kingdom | Details |