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| NCT ID | NCT03975647 |
| Title | A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Seattle Genetics, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of South Alabama - Mitchell Cancer Institute | ACTIVE_NOT_RECRUITING | Mobile | Alabama | 36604 | United States | Details |
| Ironwood Cancer & Research Centers - Chandler | COMPLETED | Chandler | Arizona | 85224 | United States | Details |
| Banner MD Anderson Cancer Center | ACTIVE_NOT_RECRUITING | Gilbert | Arizona | 85234 | United States | Details |
| Cancer Treatment Centers of America / Western Regional Medical Center | ACTIVE_NOT_RECRUITING | Goodyear | Arizona | 85338 | United States | Details |
| Arizona Oncology Associates, PC - HAL | COMPLETED | Phoenix | Arizona | 85016 | United States | Details |
| Arizona Oncology Associates, PC - HOPE | COMPLETED | Tucson | Arizona | 85710 | United States | Details |
| St. Bernards Medical Center | COMPLETED | Jonesboro | Arkansas | 72401 | United States | Details |
| City of Hope National Medical Center | COMPLETED | Duarte | California | 91010-3000 | United States | Details |
| California Cancer Associates for Research and Excellence Inc (cCARE) | COMPLETED | Encinitas | California | 92024 | United States | Details |
| St. Joseph Heritage Healthcare TRIO | COMPLETED | Fullerton | California | 92835 | United States | Details |
| Chao Family Comprehensive Cancer Center University of California Irvine | ACTIVE_NOT_RECRUITING | Orange | California | 92868 | United States | Details |
| University of California Irvine - Newport | ACTIVE_NOT_RECRUITING | Orange | California | 92868 | United States | Details |
| University of California Davis | ACTIVE_NOT_RECRUITING | Sacramento | California | 95817 | United States | Details |
| San Francisco General Hospital | COMPLETED | San Francisco | California | 94110 | United States | Details |
| University of California, San Francisco | HDFCCC - Hematopoietic Malignancies | COMPLETED | San Francisco | California | 94134 | United States | Details |
| UCLA Department of Medicine - Hematology & Oncology | ACTIVE_NOT_RECRUITING | Santa Monica | California | 90404 | United States | Details |
| Torrance Memorial Physician Network - TRIO | ACTIVE_NOT_RECRUITING | Torrance | California | 90505 | United States | Details |
| Kaiser Permanente Medical Center Northern California | ACTIVE_NOT_RECRUITING | Vallejo | California | 94589 | United States | Details |
| Rocky Mountain Cancer Centers - Aurora | ACTIVE_NOT_RECRUITING | Aurora | Colorado | 80012 | United States | Details |
| University of Colorado Hospital / University of Colorado | ACTIVE_NOT_RECRUITING | Aurora | Colorado | 80045-0510 | United States | Details |
| SCL Health Good Samaritan Medical Center Cancer Centers of Colorado | COMPLETED | Broomfield | Colorado | 80021 | United States | Details |
| University of Colorado Health Memorial Hospital | COMPLETED | Colorado Springs | Colorado | 80909 | United States | Details |
| Cancer Centers of Colorado - Denver | COMPLETED | Denver | Colorado | 80218 | United States | Details |
| Poudre Valley Health System (PVHS) | ACTIVE_NOT_RECRUITING | Fort Collins | Colorado | 80524 | United States | Details |
| Helen F. Graham Cancer Center / Christiana Care Health Systems | COMPLETED | Newark | Delaware | 19713 | United States | Details |
| Lombardi Cancer Center / Georgetown University Medical Center | ACTIVE_NOT_RECRUITING | Washington | District of Columbia | 20007 | United States | Details |
| Florida Cancer Specialists - South Region | ACTIVE_NOT_RECRUITING | Fort Myers | Florida | 33901 | United States | Details |
| Baptist MD Anderson Cancer Center | ACTIVE_NOT_RECRUITING | Jacksonville | Florida | 32207 | United States | Details |
| University of Miami | ACTIVE_NOT_RECRUITING | Miami | Florida | 33136 | United States | Details |
| Miami Cancer Institute at Baptist Health, Inc. | ACTIVE_NOT_RECRUITING | Miami | Florida | 33176 | United States | Details |
| AdventHealth Cancer Institute | ACTIVE_NOT_RECRUITING | Orlando | Florida | 32804 | United States | Details |
| Orlando Health, Inc. TRIO | ACTIVE_NOT_RECRUITING | Orlando | Florida | 32806 | United States | Details |
| Florida Cancer Specialists - North Region | ACTIVE_NOT_RECRUITING | Saint Petersburg | Florida | 33705 | United States | Details |
| H. Lee Moffitt Cancer Center and Research Institute | ACTIVE_NOT_RECRUITING | Tampa | Florida | 33612 | United States | Details |
| Florida Cancer Specialists - East West Palm Beach, FL (SCRI) | COMPLETED | West Palm Beach | Florida | 33401 | United States | Details |
| Winship Cancer Institute / Emory University School of Medicine | COMPLETED | Atlanta | Georgia | 30322 | United States | Details |
| Augusta University | ACTIVE_NOT_RECRUITING | Augusta | Georgia | 30912 | United States | Details |
| Northside Hospital | ACTIVE_NOT_RECRUITING | Canton | Georgia | 30115 | United States | Details |
| Kaiser Permanente Moanalua Medical Center | COMPLETED | Honolulu | Hawaii | 96819 | United States | Details |
| Kapi'olani Medical Center for Women and Children | ACTIVE_NOT_RECRUITING | Honolulu | Hawaii | 96826 | United States | Details |
| Illinois Cancer Specialists - Arlington Heights | COMPLETED | Arlington Heights | Illinois | 60005 | United States | Details |
| Rush University Medical Center | COMPLETED | Chicago | Illinois | 60612 | United States | Details |
| University of Chicago Medical Center | COMPLETED | Chicago | Illinois | 60637-1470 | United States | Details |
| Illinois Cancer Care | ACTIVE_NOT_RECRUITING | Peoria | Illinois | 61615 | United States | Details |
| Ft Wayne Medical Oncology and Hematology, Inc TRIO | ACTIVE_NOT_RECRUITING | Fort Wayne | Indiana | 46804 | United States | Details |
| University of Kansas Medical Center | ACTIVE_NOT_RECRUITING | Kansas City | Kansas | 66160 | United States | Details |
| CHI Saint Joseph Medical Group Cancer Care Center | COMPLETED | Lexington | Kentucky | 40509 | United States | Details |
| Ochsner Medical Center | COMPLETED | New Orleans | Louisiana | 70121 | United States | Details |
| University of Maryland | COMPLETED | Baltimore | Maryland | 21201 | United States | Details |
| Mercy Medical Center -Weinberg Center | COMPLETED | Baltimore | Maryland | 21202 | United States | Details |
| American Oncology Networks LLC | COMPLETED | Bethesda | Maryland | 20817 | United States | Details |
| Maryland Oncology Hematology, P.A. | ACTIVE_NOT_RECRUITING | Rockville | Maryland | 20850 | United States | Details |
| Beth Israel Deaconess Medical Center | COMPLETED | Boston | Massachusetts | 02215 | United States | Details |
| Dana Farber Cancer Institute | ACTIVE_NOT_RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| University of Michigan Comprehensive Cancer Center | ACTIVE_NOT_RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| Henry Ford Health System | ACTIVE_NOT_RECRUITING | Detroit | Michigan | 48202 | United States | Details |
| Minnesota Oncology Hematology P.A. | ACTIVE_NOT_RECRUITING | Minneapolis | Minnesota | 55404 | United States | Details |
| North Mississippi Medical Center Hematology Oncology - Tupelo | COMPLETED | Tupelo | Mississippi | 38801 | United States | Details |
| Saint Luke's Cancer Institute LLC | ACTIVE_NOT_RECRUITING | Kansas City | Missouri | 64113 | United States | Details |
| HCA Midwest Health Kansas City | ACTIVE_NOT_RECRUITING | Kansas City | Missouri | 64132 | United States | Details |
| Washington University in St Louis | ACTIVE_NOT_RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| St. Vincent Frontier Cancer Center | ACTIVE_NOT_RECRUITING | Billings | Montana | 59102 | United States | Details |
| Nebraska Cancer Specialists | ACTIVE_NOT_RECRUITING | Omaha | Nebraska | 68130 | United States | Details |
| Comprehensive Cancer Centers of Nevada | ACTIVE_NOT_RECRUITING | Las Vegas | Nevada | 89169 | United States | Details |
| Summit Medical Group | COMPLETED | Florham Park | New Jersey | 07932 | United States | Details |
| Saint Barnabas Medical Center Cancer Center | ACTIVE_NOT_RECRUITING | Livingston | New Jersey | 07039 | United States | Details |
| Rutgers Cancer Institute of New Jersey | ACTIVE_NOT_RECRUITING | New Brunswick | New Jersey | 08903-2681 | United States | Details |
| New York Oncology Hematology, P.C. | ACTIVE_NOT_RECRUITING | Albany | New York | 12206 | United States | Details |
| Stony Brook University Cancer Center | COMPLETED | Stony Brook | New York | 11794-7263 | United States | Details |
| UNC Lineberger Comprehensive Cancer Center / University of North Carolina | COMPLETED | Chapel Hill | North Carolina | 27599 | United States | Details |
| Levine Cancer Institute | COMPLETED | Charlotte | North Carolina | 28204 | United States | Details |
| Duke University Medical Center | ACTIVE_NOT_RECRUITING | Durham | North Carolina | 27710 | United States | Details |
| Providence Portland Medical Center | ACTIVE_NOT_RECRUITING | Portland | Oregon | 97213 | United States | Details |
| Oregon Health and Science University | ACTIVE_NOT_RECRUITING | Portland | Oregon | 97239-3098 | United States | Details |
| Northwest Cancer Specialists, P.C. | COMPLETED | Tigard | Oregon | 97223 | United States | Details |
| University of Pennsylvania / Perelman Center for Advanced Medicine | ACTIVE_NOT_RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Cancer Treatment Centers of America / Eastern Regional Medical Center | COMPLETED | Philadelphia | Pennsylvania | 19124 | United States | Details |
| Brig Center for Cancer Care and Survivorship | COMPLETED | Knoxville | Tennessee | 37909 | United States | Details |
| Tennessee Oncology-Nashville/Sarah Cannon Research Institute | ACTIVE_NOT_RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Texas Oncology - Amarillo | COMPLETED | Amarillo | Texas | 79124 | United States | Details |
| Texas Oncology - Austin Central | ACTIVE_NOT_RECRUITING | Austin | Texas | 78731 | United States | Details |
| Texas Oncology - DFW | ACTIVE_NOT_RECRUITING | Bedford | Texas | 76022 | United States | Details |
| Texas Oncology - Methodist Dallas Cancer Center | ACTIVE_NOT_RECRUITING | Dallas | Texas | 75203 | United States | Details |
| Texas Oncology - Medical City Dallas | COMPLETED | Dallas | Texas | 75230 | United States | Details |
| Texas Oncology - Baylor Sammons Cancer Center | ACTIVE_NOT_RECRUITING | Dallas | Texas | 75246 | United States | Details |
| University of Texas Southwestern Medical Center | COMPLETED | Dallas | Texas | 75390 | United States | Details |
| The Center for Cancer and Blood Disorders: Fortworth | ACTIVE_NOT_RECRUITING | Fort Worth | Texas | 76104 | United States | Details |
| Texas Oncology - Houston Memorial City | ACTIVE_NOT_RECRUITING | Houston | Texas | 77024 | United States | Details |
| MD Anderson Cancer Center / University of Texas | COMPLETED | Houston | Texas | 77030-4095 | United States | Details |
| Baylor Clinic | ACTIVE_NOT_RECRUITING | Houston | Texas | 77030 | United States | Details |
| Oncology Consultants, PA | COMPLETED | Houston | Texas | 77030 | United States | Details |
| Texas Oncology - San Antonio Medical Center | ACTIVE_NOT_RECRUITING | San Antonio | Texas | 78240 | United States | Details |
| Huntsman Cancer Institute/University of Utah | COMPLETED | Salt Lake City | Utah | 84112 | United States | Details |
| Virginia Cancer Specialists, PC | ACTIVE_NOT_RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| Saint Francis Hospital / Bon Secours - Virginia | COMPLETED | Midlothian | Virginia | 23114 | United States | Details |
| Peninsula Cancer Institute | COMPLETED | Newport News | Virginia | 23601 | United States | Details |
| Oncology and Hematology Assoc of SW VA DBA Blue Ridge Cancer Care | ACTIVE_NOT_RECRUITING | Salem | Virginia | 24153 | United States | Details |
| Swedish Cancer Institute - Edmonds | ACTIVE_NOT_RECRUITING | Edmonds | Washington | 98026 | United States | Details |
| Swedish Cancer Institute - Issaquah | ACTIVE_NOT_RECRUITING | Issaquah | Washington | 98029 | United States | Details |
| Swedish Cancer Institute | ACTIVE_NOT_RECRUITING | Seattle | Washington | 98104 | United States | Details |
| Peter MacCallum Cancer Centre | ACTIVE_NOT_RECRUITING | Melbourne | Other | 3000 | Australia | Details |
| Austin Health | ACTIVE_NOT_RECRUITING | Melbourne | Other | 3084 | Australia | Details |
| Breast Cancer Research Centre | ACTIVE_NOT_RECRUITING | Nedlands | Other | 6009 | Australia | Details |
| Mater Hospital | ACTIVE_NOT_RECRUITING | Sydney | Other | 2060 | Australia | Details |
| Westmead Hospital | ACTIVE_NOT_RECRUITING | Westmead | Other | 2145 | Australia | Details |
| LKH- Universitat Klinikum Graz | COMPLETED | Graz | Other | 8036 | Austria | Details |
| Medizinische Universitat Innsbruck | COMPLETED | Innsbruck | Other | 6020 | Austria | Details |
| LKH Salzburg, Universitatsklinikum der PMU | COMPLETED | Salzburg | Other | 5020 | Austria | Details |
| Medizinische Universitat Wien | COMPLETED | Vienna | Other | 1090 | Austria | Details |
| Klinik Ottakring | COMPLETED | Vienna | Other | 1160 | Austria | Details |
| Institut Jules Bordet | ACTIVE_NOT_RECRUITING | Anderlecht | Other | B-1070 | Belgium | Details |
| Cliniques Universitaires Saint Luc | COMPLETED | Brussels | Other | 1200 | Belgium | Details |
| Grand Hôpital de Charleroi - Saint-Joseph | COMPLETED | Charleroi | Other | 6000 | Belgium | Details |
| Universitair Ziekenhuis Antwerpen | ACTIVE_NOT_RECRUITING | Edegem | Other | 2650 | Belgium | Details |
| Academisch Ziekenhuis Groeninge | ACTIVE_NOT_RECRUITING | Kortrijk | Other | 8500 | Belgium | Details |
| CHU de Liege | ACTIVE_NOT_RECRUITING | Liege | Other | 4000 | Belgium | Details |
| Universitair Ziekenhuis Leuven | ACTIVE_NOT_RECRUITING | Lueven | Other | 3000 | Belgium | Details |
| CHU UCL Namur-Site de Saint Elisabeth | ACTIVE_NOT_RECRUITING | Namur | Other | 5000 | Belgium | Details |
| University of Alberta / Cross Cancer Institute | ACTIVE_NOT_RECRUITING | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| Queen Elizabeth II Health Sciences Centre | COMPLETED | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details |
| Cancer Centre of Southeastern Ontario At Kingston General Hospital | COMPLETED | Kingston | Ontario | K7L 5P9 | Canada | Details |
| London Health Sciences Centre - Victoria Hospital | ACTIVE_NOT_RECRUITING | London | Ontario | N6A 5W9 | Canada | Details |
| University of Ottawa / Ottawa General Hospital | ACTIVE_NOT_RECRUITING | Ottawa | Ontario | K1H 8L6 | Canada | Details |
| University Health Network, Princess Margaret Hospital | ACTIVE_NOT_RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Centre Hospitalier de l'Universite de Montreal | ACTIVE_NOT_RECRUITING | Montreal | Quebec | H2X 3E4 | Canada | Details |
| Jewish General Hospital | COMPLETED | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Saskatoon Cancer Centre | COMPLETED | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details |
| Hopital du Saint-Sacrement, CHU de Quebec-Universite Laval | ACTIVE_NOT_RECRUITING | Quebec | G1S 4L8 | Canada | Details | |
| Cancer Hospital Chinese Academy of Medical Sciences | RECRUITING | Beijing City | Other | 100021 | China | Details |
| Peking University People's Hospital | RECRUITING | Beijing | Other | 100044 | China | Details |
| Jilin Province Cancer Hospital | RECRUITING | Changghun | Other | 130012 | China | Details |
| Hunan Cancer Hospital | RECRUITING | Changsha | Other | 410013 | China | Details |
| Sun Yat-sen University Cancer Center | RECRUITING | Guangzhou City | Other | 510060 | China | Details |
| Guangdong Provincial People's Hospital | RECRUITING | Guangzhou | Other | 510080 | China | Details |
| Zhejiang Cancer Hospital | RECRUITING | Hangzhou City | Other | 310022 | China | Details |
| First Affiliated Hospital of Zhejiang University | COMPLETED | Hangzhou City | Other | China | Details | |
| The Second Affiliated Hospital of Zhejiang University School of Medicine | RECRUITING | Hangzhou | Other | 0571 | China | Details |
| Shandong Cancer Hospital | RECRUITING | Jinan | Other | 250117 | China | Details |
| Gulou Hospital Affiliated to Nanjing University Medical College | RECRUITING | Nanjing | Other | 210008 | China | Details |
| Shengjing Hospital of China Medical University | RECRUITING | Shenyang City | Other | 110022 | China | Details |
| Tianjin Medical University - Cancer Institute & Hospital | RECRUITING | Tianjin | Other | 453000 | China | Details |
| Hubei Cancer Hospital | RECRUITING | Wuhan | Other | 430000 | China | Details |
| Wuhan University | RECRUITING | Wuhan | Other | 430060 | China | Details |
| The First Affiliated Hospital of Xi'an Jiaotong University | RECRUITING | Xi'an | Other | 710061 | China | Details |
| Xi'An International Medical Center Hospital | RECRUITING | Xi'An | Other | 710100 | China | Details |
| Xuzhou Central Hospital | RECRUITING | Xuzhou | Other | 221009 | China | Details |
| The Affiliated Hospital of Xuzhou Medical College | RECRUITING | Xuzhou | Other | 22100 | China | Details |
| The Affiliated Hospital of Guangdong Medical University | RECRUITING | Zhan Jiang City | Other | 524000 | China | Details |
| Henan Cancer Hospital | RECRUITING | Zhengzhou | Other | 45003 | China | Details |
| Zigong First People's Hospital | RECRUITING | Zigong City | Other | 643000 | China | Details |
| Bejing Hospital | RECRUITING | Bejing | China | Details | ||
| Center of Women and Children Hospital of Guangdong Province | RECRUITING | Guangzhou | 511400 | China | Details | |
| Nanchang Third Hospital | RECRUITING | Nanchang City | 330009 | China | Details | |
| Guangxi Medical University Affiliated Tumor Hospital | RECRUITING | Nanning | 530021 | China | Details | |
| Aalborg Universitetshospital | COMPLETED | Aalborg | Other | 9100 | Denmark | Details |
| Aarhus University Hospital | COMPLETED | Aarhus N | Other | 8200 | Denmark | Details |
| Rigs Hospiltalet | COMPLETED | Copenhagen | Other | 2100 | Denmark | Details |
| Herlev Hospital | ACTIVE_NOT_RECRUITING | Herlev | Other | 2730 | Denmark | Details |
| Odense University Hospital | ACTIVE_NOT_RECRUITING | Odense C | Other | 5000 | Denmark | Details |
| Sygehus Lillebaelt - Vejle Sygehus | ACTIVE_NOT_RECRUITING | Vejle | Other | 7100 | Denmark | Details |
| University Hospital of Besancon | ACTIVE_NOT_RECRUITING | Besancon cedex | Other | 25030 | France | Details |
| Hospital Center Regional University Morvan De Brest | COMPLETED | Brest | Other | 29200 | France | Details |
| Centre de Lutte contre le Cancer - Francois Baclesse | ACTIVE_NOT_RECRUITING | Caen Cedex 5 | Other | 14076 | France | Details |
| Hopital Europeen Georges Pompidou | COMPLETED | Cedex 15 | Other | 75908 | France | Details |
| Center Georges Francois Leclerc | ACTIVE_NOT_RECRUITING | Dijon | Other | 21000 | France | Details |
| Clinique Victor Hugo Le Mans | ACTIVE_NOT_RECRUITING | Le Mans | Other | 72000 | France | Details |
| Centre Leon Berard - Centre regional de lutte contre le cancer Rhone-Alpes | ACTIVE_NOT_RECRUITING | Lyon cedex 08 | Other | 69008 | France | Details |
| Institut Paoli Calmettes | ACTIVE_NOT_RECRUITING | Marseille | Other | 13273 | France | Details |
| Hopital Saint-Louis / Service d'Hematologie | COMPLETED | Paris Cedex 10 | Other | 75475 | France | Details |
| Institute Curie - Centre de Lutte Contre Le Cancer CLCC de Paris | ACTIVE_NOT_RECRUITING | Paris | Other | 75298 CEDEX 05 | France | Details |
| Centre Henri Becquerel / Centre Regional de Lutte Contre le Cancer | COMPLETED | Rouen | Other | 76038 | France | Details |
| Hopitaux Universitaires de Strasbourg | ACTIVE_NOT_RECRUITING | Strasbourg | Other | 67200 | France | Details |
| Institut Claudius Regaud IUCT-O | ACTIVE_NOT_RECRUITING | Toulouse Cedex 9 | Other | 31059 | France | Details |
| CHU Tours - Hopital Bretonneau | ACTIVE_NOT_RECRUITING | TOURS Cedex 09 | Other | 37044 | France | Details |
| Helios Klinikum Berlin-Buch | COMPLETED | Berlin | Other | 13125 | Germany | Details |
| Stadtisches Klinikum Dessau | COMPLETED | Dessau-Rosslau | Other | 06847 | Germany | Details |
| Kliniken Essen-Mitte - Evang. Huyssens-Stiftung | COMPLETED | Essen | Other | 45136 | Germany | Details |
| CHOP GmbH | COMPLETED | Frankfurt | Other | 60389 | Germany | Details |
| Universitaetsklinikum Hamburg-Eppendorf (UKE) | COMPLETED | Hamburg | Other | 20246 | Germany | Details |
| Universitatsklinikum Heidelberg | COMPLETED | Heidelberg | Other | 69120 | Germany | Details |
| Universitatsklinikum Schleswig-Holstein | ACTIVE_NOT_RECRUITING | Kiel | Other | 24105 | Germany | Details |
| InVO- Institut fUr Versorgungsforschung in der onkologie GbR | ACTIVE_NOT_RECRUITING | Koblenz | Other | 56068 | Germany | Details |
| Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz | ACTIVE_NOT_RECRUITING | Mainz | Other | 55101 | Germany | Details |
| Klinikum Rechts der Isar der Technischen Universitaet Muenchen | ACTIVE_NOT_RECRUITING | Muenchen | Other | 81675 | Germany | Details |
| Klinikum der Universitat Munchen | COMPLETED | Munchen | Other | 80337 | Germany | Details |
| Sana Klinikum Offenbach GmbH | COMPLETED | Offenbach am Main | Other | 63069 | Germany | Details |
| University of Rostock | COMPLETED | Rostock | Other | 18059 | Germany | Details |
| Shaare Zedek Medical Center | COMPLETED | Jerusalem | Other | 9103102 | Israel | Details |
| Meir Medical Center | COMPLETED | Kfar Saba | Other | 44281 | Israel | Details |
| Rabin Medical Center | ACTIVE_NOT_RECRUITING | Petach Tikva | Other | 49414 | Israel | Details |
| Kaplan Medical Center | ACTIVE_NOT_RECRUITING | Rehovot | Other | 76100 | Israel | Details |
| Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi | COMPLETED | Bologna | Other | 40138 | Italy | Details |
| Fondazione del Piemonte per l'Oncologia - Istituto di Candiolo FPO - IRCCS | COMPLETED | Candiolo | Other | 10060 | Italy | Details |
| Irccs Irst | COMPLETED | Meldola | Other | 47014 | Italy | Details |
| Istituto Europeo di Oncologia | ACTIVE_NOT_RECRUITING | Milano | Other | 20141 | Italy | Details |
| Seconda Università degli Studi di Napoli, AOU | COMPLETED | Napoli | Other | 80131 | Italy | Details |
| Nuovo Ospedale di Prato - Santo Stefano | COMPLETED | Prato | Other | 59100 | Italy | Details |
| Ospedale degli Infermi | COMPLETED | Rimini | Other | 47923 | Italy | Details |
| Policlinico Universitario Agostino Gemelli | COMPLETED | Roma | Other | 00168 | Italy | Details |
| Azienda Ospedaliera S. Maria di Terni | COMPLETED | Terni | Other | 05100 | Italy | Details |
| A.O.U. - Ospedali Riuniti di Ancona | COMPLETED | Torrette | Other | 60126 | Italy | Details |
| Chiba Cancer Center | ACTIVE_NOT_RECRUITING | Chiba | Other | 260-8717 | Japan | Details |
| National Cancer Center Hospital | ACTIVE_NOT_RECRUITING | Chuo-ku | Other | 104-0045 | Japan | Details |
| National Hospital Organization Kyushu Cancer Center | ACTIVE_NOT_RECRUITING | Fukuoka-shi | Other | 811-1395 | Japan | Details |
| Hiroshima City Hiroshima Citizens Hospital | ACTIVE_NOT_RECRUITING | Hiroshima | Other | 730-8518 | Japan | Details |
| University of Tsukuba Hospital | ACTIVE_NOT_RECRUITING | Ibaraki | Other | 305-8576 | Japan | Details |
| Hakuaikai Sagara Hospital/Breast Surgery | ACTIVE_NOT_RECRUITING | Kagosima | Other | 892-0833 | Japan | Details |
| Kameda General Hospital | COMPLETED | Kamogawa | Other | 296-8602 | Japan | Details |
| National Cancer Center Hospital East | ACTIVE_NOT_RECRUITING | Kashiwa-shi | Other | 277-8577 | Japan | Details |
| Saitama Cancer Center | ACTIVE_NOT_RECRUITING | Kitaadachi-gun | Other | 362-0806 | Japan | Details |
| Kumamoto Shinto General Hospital | ACTIVE_NOT_RECRUITING | Kumamoto | Other | 862-8655 | Japan | Details |
| NHO Shikoku Cancer Center | ACTIVE_NOT_RECRUITING | Matsuyama | Other | 791-0280 | Japan | Details |
| Aichi Cancer Center | ACTIVE_NOT_RECRUITING | Nagoya-shi | Other | 464-8681 | Japan | Details |
| Hyogo College of Medicine Hospital | ACTIVE_NOT_RECRUITING | Nishinomiya | Other | 730-8518 | Japan | Details |
| National Hospital Organization Osaka | ACTIVE_NOT_RECRUITING | Osaka | Other | 540-0006 | Japan | Details |
| Osaka International Cancer Institute | ACTIVE_NOT_RECRUITING | Osaka | Other | 541-8567 | Japan | Details |
| National Hospital Organization Hokkaido Cancer Center | ACTIVE_NOT_RECRUITING | Sapporo | Other | 003-0804 | Japan | Details |
| Shizuoka Cancer Center | ACTIVE_NOT_RECRUITING | Sunto-Gun | Other | 411-8777 | Japan | Details |
| The Cancer Institute Hospital of JFCR | ACTIVE_NOT_RECRUITING | Tokyo | Other | 135-8550 | Japan | Details |
| Kanagawa Cancer Center | ACTIVE_NOT_RECRUITING | Yokohama | Other | 241-8515 | Japan | Details |
| National Cancer Center | ACTIVE_NOT_RECRUITING | Goyang-si | Other | 10408 | Korea, Republic of | Details |
| Seoul National University Bundang Hospital | ACTIVE_NOT_RECRUITING | Seongnam-si | Other | 13605 | Korea, Republic of | Details |
| Korea University Anam Hospital | ACTIVE_NOT_RECRUITING | Seoul | Other | 02841 | Korea, Republic of | Details |
| Seoul National University Hospital | ACTIVE_NOT_RECRUITING | Seoul | Other | 03080 | Korea, Republic of | Details |
| Severance Hospital, Yonsei University Health System | ACTIVE_NOT_RECRUITING | Seoul | Other | 03722 | Korea, Republic of | Details |
| Asan Medical Center - Oncology | ACTIVE_NOT_RECRUITING | Seoul | Other | 05505 | Korea, Republic of | Details |
| Samsung Medical Center | ACTIVE_NOT_RECRUITING | Seoul | Other | 06351 | Korea, Republic of | Details |
| Isala Ziekenhuis Zwolle | COMPLETED | AB Zwolle | Other | 8025 | Netherlands | Details |
| Netherlands Cancer Institute | ACTIVE_NOT_RECRUITING | Amsterdam | Other | 1066 WX | Netherlands | Details |
| Amphia Ziekenhuis | ACTIVE_NOT_RECRUITING | Breda | Other | 4818 CK | Netherlands | Details |
| Reinier de Graaf Hospital | COMPLETED | Delft | Other | 2625 | Netherlands | Details |
| University Medical Center Groningen | COMPLETED | Groningen | Other | 9713 GZ | Netherlands | Details |
| Martini Ziekenhuis | COMPLETED | Groningen | Other | 9728 | Netherlands | Details |
| Maastricht University Medical Center | COMPLETED | Maastricht | Other | 6229 HX | Netherlands | Details |
| Erasmus Medisch Centrum Daniel Den Hoed | ACTIVE_NOT_RECRUITING | Rotterdam | Other | 3015GD | Netherlands | Details |
| National University Cancer Institute, Singapore | ACTIVE_NOT_RECRUITING | Singapore | Other | 119228 | Singapore | Details |
| National Cancer Centre Singapore | ACTIVE_NOT_RECRUITING | Singapore | Other | 169610 | Singapore | Details |
| Hospital del Mar | COMPLETED | Barcelona | Other | 08003 | Spain | Details |
| Hospital Universitari Vall d'Hebron | ACTIVE_NOT_RECRUITING | Barcelona | Other | 08035 | Spain | Details |
| Hospital Universitario Reina Sofia | COMPLETED | Cordoba | Other | 14004 | Spain | Details |
| Hospital General Universitario Gregorio Marañon | COMPLETED | Madrid | Other | 28007 | Spain | Details |
| Hospital Ruber Internacional | COMPLETED | Madrid | Other | 28034 | Spain | Details |
| Hospital Clinico San Carlos | ACTIVE_NOT_RECRUITING | Madrid | Other | 28040 | Spain | Details |
| Hospital Universitario HM Sanchinarro | ACTIVE_NOT_RECRUITING | Madrid | Other | 28050 | Spain | Details |
| Hospital Universitario Virgen de la Victoria | COMPLETED | Malaga | Other | 29010 | Spain | Details |
| Hospital Universitario Son Espases | ACTIVE_NOT_RECRUITING | Palma de Mallorca | Other | 07120 | Spain | Details |
| L'Institut Catala d'Oncologia | ACTIVE_NOT_RECRUITING | Saint Joan Despi | Other | 08970 | Spain | Details |
| Hospital Universitario de Canarias | ACTIVE_NOT_RECRUITING | San Cristóbal de la Laguna | Other | 38320 | Spain | Details |
| Hospital Universitario Virgen del Rocio | ACTIVE_NOT_RECRUITING | Sevilla | Other | 41013 | Spain | Details |
| Hospital Clinico Universitario de Valencia | ACTIVE_NOT_RECRUITING | Valencia | Other | 46010 | Spain | Details |
| Hospital Universitario Miguel Servet | ACTIVE_NOT_RECRUITING | Zaragoza | Other | 50009 | Spain | Details |
| Goteborgs Universitet - Sahlgrenska Akademin - Institutionen For Kliniska Vetenskaper (Institute Of Clinical Sciences) | ACTIVE_NOT_RECRUITING | Gothenburg | Other | SE-40530 | Sweden | Details |
| Ryhov Hospital | ACTIVE_NOT_RECRUITING | Jonkoping | Other | 55185 | Sweden | Details |
| Skanes University Hospital - Universitetssjukhus | COMPLETED | Lund | Other | 22185 | Sweden | Details |
| Orebro University Hospital | COMPLETED | Orebro | Other | 70185 | Sweden | Details |
| Onkologklinike Sodersjukhuset | COMPLETED | Stockholm | Other | S-11883 | Sweden | Details |
| University Hospital Basel - Brustzentrum | COMPLETED | Basel | Other | 4031 | Switzerland | Details |
| Institute of Oncology of Southern Switzerland | COMPLETED | Bellinzona | Other | 6500 | Switzerland | Details |
| University Hospital Lausanne CHUV | ACTIVE_NOT_RECRUITING | Lausanne | Other | 1011 | Switzerland | Details |
| Kantonsspital Winterthur (KSW) | ACTIVE_NOT_RECRUITING | Winterthur | Other | 8400 | Switzerland | Details |
| National Cheng-Kung University Hospital | ACTIVE_NOT_RECRUITING | Tainan | Other | 704 | Taiwan | Details |
| National Taiwan University Hospital | ACTIVE_NOT_RECRUITING | Tainan | Other | 704 | Taiwan | Details |
| University Hospitals Birmingham NHS Foundation Trust | COMPLETED | Birmingham | Other | B15 2TH | United Kingdom | Details |
| Addenbrooke's Hospital | COMPLETED | Cambridge | Other | CB2 0QQ | United Kingdom | Details |
| The University of Edinburgh | ACTIVE_NOT_RECRUITING | Edinburgh | Other | EH4 2XU | United Kingdom | Details |
| Oxford University Hospitals | COMPLETED | Headington | Other | OX3 7LE | United Kingdom | Details |
| The Royal Marsden NHS Foundation Trust (RM) | ACTIVE_NOT_RECRUITING | London | Other | SW3 6JJ | United Kingdom | Details |
| Sarah Cannon Research Institute UK | COMPLETED | London | Other | W1G 6AD | United Kingdom | Details |
| Maidstone and Tunbridge Wells NHS Trust | COMPLETED | Maidstone | Other | ME16 9QQ | United Kingdom | Details |
| The Christie NHS Foundation Trust | ACTIVE_NOT_RECRUITING | Manchester | Other | M20 4BX | United Kingdom | Details |
| The Newcastle upon Tyne Hospitals NHS Foundation Trust | COMPLETED | Newcastle Upon Tyne | Other | NE7 7DN | United Kingdom | Details |
| Mount Vernon Hospital, UK | COMPLETED | Northwood | Other | HA6 2RN | United Kingdom | Details |
| The Royal Marsden Hospital (Surrey) | COMPLETED | Sutton | Other | SM2 5PT | United Kingdom | Details |
| Royal Cornwall Hospitals NHS Trust | COMPLETED | Truro | Other | TR1 3LQ | United Kingdom | Details |