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NCT ID NCT03976323
Title Study of Pembrolizumab With Maintenance Olaparib or Maintenance Pemetrexed in First-line (1L) Metastatic Nonsquamous Non-Small-Cell Lung Cancer (NSCLC) (MK-7339-006, KEYLYNK-006)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications

lung non-squamous non-small cell carcinoma

Therapies

Pembrolizumab + Pemetrexed Disodium

Carboplatin + Pembrolizumab + Pemetrexed Disodium

Olaparib + Pembrolizumab

Cisplatin + Pembrolizumab + Pemetrexed Disodium

Age Groups: senior | adult
Covered Countries USA | FRA | ESP | DEU | CAN | AUT

Facility Status City State Zip Country Details
Alabama Oncology Bruno Cancer Center ( Site 0001) Birmingham Alabama 35205 United States Details
Northwest Alabama Cancer Center, PC ( Site 0002) Muscle Shoals Alabama 35661 United States Details
Disney Family Cancer Center ( Site 0005) Burbank California 91505 United States Details
Boca Raton Regional Hospital ( Site 0018) Boca Raton Florida 33486 United States Details
Mid-Florida Cancer Centers ( Site 0022) Orange City Florida 32763 United States Details
Moffitt Cancer Center ( Site 0024) Tampa Florida 33612 United States Details
Columbus Regional Research Institute ( Site 0098) Columbus Georgia 31904 United States Details
Mount Sinai Hospital Medical Center ( Site 0032) Chicago Illinois 60608 United States Details
Oncology of Northshore ( Site 0033) Rolling Meadows Illinois 60008 United States Details
Methodists Hospitals/Premier Oncology Hematology Associates ( Site 0036) Merrillville Indiana 46410 United States Details
Medstar Good Samaritan Hospital ( Site 0040) Baltimore Maryland 21239 United States Details
Barbara Ann Karmanos Cancer Institute ( Site 0041) Detroit Michigan 48201 United States Details
Hattiesburg Clinic ( Site 0045) Hattiesburg Mississippi 39401 United States Details
Frontier Oncology ( Site 0080) Billings Montana 59102 United States Details
Bozeman Health Deaconness Cancer Center ( Site 0046) Bozeman Montana 59715 United States Details
Waverly Hematology Oncology ( Site 0081) Cary North Carolina 27518 United States Details
Thompson Cancer Survival Center ( Site 2812) Knoxville Tennessee 37804 United States Details
University of Tennessee Medical Center Knoxville ( Site 0060) Knoxville Tennessee 37920 United States Details
Renovatio Clinical ( Site 0062) The Woodlands Texas 77380 United States Details
Cancer Care Northwest ( Site 0071) Spokane Valley Washington 99216 United States Details
Hospital Italiano Regional del Sur ( Site 0509) Bahia Blanca Buenos Aires B8001HXM Argentina Details
Hospital Britanico de Buenos Aires ( Site 0500) Buenos Aires Caba C1280AEB Argentina Details
Instituto Medico Rio Cuarto ( Site 0501) Rio Cuarto Cordoba X5800AEV Argentina Details
Centro Oncológico de Rosario ( Site 0507) Rosario Santa Fe Rosario Argentina Details
Centro Medico San Roque ( Site 0506) San Miguel de Tucuman Tucuman T4000IAK Argentina Details
Hospital Italiano de Buenos Aires ( Site 0511) Buenos Aires C1199ABB Argentina Details
Clínica Universitaria Reina Fabiola ( Site 0505) Cordoba Argentina Details
Sanatorio Privado San Geronimo S.R.L ( Site 0510) Santa Fe S3000AOL Argentina Details
Liverpool Hospital ( Site 1201) Liverpool New South Wales 2170 Australia Details
Southern Medical Day Care Centre ( Site 1200) Wollongong New South Wales 2500 Australia Details
Townsville General Hospital ( Site 1202) Townsville Queensland 4814 Australia Details
Monash Cancer Centre ( Site 1205) Clayton Victoria 3168 Australia Details
Ordensklinikum Linz GmbH Elisabethinen ( Site 1307) Linz Oberosterreich 4020 Austria Details
Klinikum Wels-Grieskirchen ( Site 1304) Wels Oberosterreich 4600 Austria Details
Innsbruck LKH ( Site 1302) Innsbruck Tirol 6020 Austria Details
Social Medical Center - Otto Wagner Hospital ( Site 1301) Vienna Wien 1145 Austria Details
Krankenhaus Nord - Klinik Floridsdorf ( Site 1300) Wien 1210 Austria Details
Hospital Sao Rafael ( Site 0212) Salvador Bahia 41253-190 Brazil Details
Instituto do Cancer do Ceara ( Site 0201) Fortaleza Ceara 60430-230 Brazil Details
Oncologica do Brasil ( Site 0210) Belem Para 66053-000 Brazil Details
Hospital Tacchini ( Site 0208) Bento Goncalves Rio Grande Do Sul 95700-000 Brazil Details
Irmandade da Santa Casa de Misericordia de Porto Alegre ( Site 0209) Porto Alegre Rio Grande Do Sul 90050-170 Brazil Details
Saint Gallen Instituto de Oncologia ( Site 0206) Santa Cruz do Sul Rio Grande Do Sul 96810-110 Brazil Details
YNOVA Pesquisa Clinica ( Site 0215) Florianopolis Santa Catarina 88020-210 Brazil Details
Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 0202) Itajai Santa Catarina 88301-220 Brazil Details
Centro de Hematologia e Oncologia ( Site 0205) Joinville Santa Catarina 89201-260 Brazil Details
Hospital de Base de Sao Jose de Rio Preto ( Site 0204) Sao Jose Rio Preto Sao Paulo 15090-000 Brazil Details
Instituto Nacional do Cancer Jose Alencar Gomes da Silva INCA ( Site 0203) Rio de Janeiro 20230-130 Brazil Details
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0200) Sao Paulo 01246-000 Brazil Details
Hospital Paulistano - Amil Clinical Research ( Site 0207) Sao Paulo 01321-001 Brazil Details
Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 0214) Sao Paulo 01321-001 Brazil Details
Lions Gate Hospital ( Site 0106) North Vancouver British Columbia V7L 2L7 Canada Details
BC Cancer - Victoria ( Site 0109) Victoria British Columbia V8R 6V5 Canada Details
Queen Elizabeth II Health Sciences Centre ( Site 0107) Halifax Nova Scotia B3H 2Y9 Canada Details
Grand River Hospital ( Site 0117) Kitchener Ontario N2G 1G3 Canada Details
Stronach Regional Cancer Centre ( Site 0101) Newmarket Ontario L3Y 2P9 Canada Details
Health Sciences North Research Institute ( Site 0115) Sudbury Ontario P3E 5J1 Canada Details
CISSS de la Monteregie-Centre ( Site 0114) Greenfield Park Quebec J4V 2H1 Canada Details
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0105) Montreal Quebec H2X 0C1 Canada Details
CIUSSS Ouest de l Ile - St-Mary s Hospital ( Site 0110) Montreal Quebec H3T 1M5 Canada Details
Centre de Sante et des Services Sociaux de Rimouski-Neigette ( Site 0104) Rimouski Quebec G5L 5T1 Canada Details
CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0103) Sherbrooke Quebec J1H 5N4 Canada Details
Fundacion Colombiana de Cancerologia Clinica Vida ( Site 0604) Medellin Antioquia 050030 Colombia Details
Clinica de la Costa Ltda. ( Site 0608) Barranquilla Atlantico 080020 Colombia Details
Administradora Country S.A. ( Site 0603) Bogota Distrito Capital De Bogota 110221 Colombia Details
Clinica Colsanitas S.A. Sede Clinica Universitaria Colombia ( Site 0601) Bogota Distrito Capital De Bogota 110311 Colombia Details
Centre Hospitalier De Chauny ( Site 1411) Chauny Aisne 02300 France Details
CHU Caen ( Site 1406) Caen Calvados 14033 France Details
CHU Angers ( Site 1405) Angers Maine-et-Loire 49100 France Details
Institut De Cancerologie De Lorraine ( Site 1409) Vandoeuvre les Nancy Meurthe-et-Moselle 54519 France Details
Hopital Robert Schuman ( Site 1402) Vantoux Moselle 57070 France Details
Centre Jean Perrin ( Site 1407) Clermont Ferrand Puy-de-Dome 63011 France Details
Centre Hospitalier de Pau ( Site 1412) Pau Pyrenees-Atlantiques 64000 France Details
CHU de Rouen ( Site 1403) Rouen Seine-Maritime 76000 France Details
Hopital d'Instruction des Armees Begin ( Site 1413) Saint-Mande Val-de-Marne 94163 France Details
Studienzentrum Aschaffenburg ( Site 1525) Aschaffenburg Bayern 63739 Germany Details
Klinikum Bogenhausen Staedt. Klinikum Muenchen GmbH ( Site 1523) Muenchen Bayern 81925 Germany Details
Klinikum der LMU ( Site 1500) Munich Bayern 80336 Germany Details
Universitaetsklinikum Regensburg ( Site 1512) Regensburg Bayern 93053 Germany Details
Klinikum Wuerzburg Mitte gGmbH ( Site 1509) Wuerzburg Bayern 97074 Germany Details
Universitaetsklinikum Frankfurt ( Site 1513) Frankfurt Hessen 60590 Germany Details
Pneumologische Lehrklinik Universitaet Goettingen ( Site 1501) Immenhausen Hessen 34376 Germany Details
Universitaetsmedizin Goettingen ( Site 1507) Goettingen Niedersachsen 37075 Germany Details
Universitaetsklinikum Bonn ( Site 1524) Bonn Nordrhein-Westfalen 53127 Germany Details
Kliniken Essen Mitte ( Site 1517) Essen Nordrhein-Westfalen 45136 Germany Details
InVo-Institut fuer Versorgungsforschung in der Onkologie ( Site 1514) Koblenz Rheinland-Pfalz 56068 Germany Details
Helios Klinikum Erfurt GmbH ( Site 1502) Erfurt Thuringen 99089 Germany Details
Katholisches Marienkrankenhaus gGmbH ( Site 1522) Hamburg 22087 Germany Details
National Hospital Organization Nagoya Medical Center ( Site 0806) Nagoya Aichi 460-0001 Japan Details
Aichi Cancer Center Hospital ( Site 0803) Nagoya Aichi 464-8681 Japan Details
National Cancer Center Hospital East ( Site 0801) Kashiwa Chiba 277-8577 Japan Details
Kanazawa University Hospital ( Site 0811) Kanazawa Ishikawa 920-8641 Japan Details
Kanagawa Cancer Center ( Site 0807) Yokohama Kanagawa 241-8515 Japan Details
Sendai Kousei Hospital ( Site 0812) Sendai Miyagi 980-0873 Japan Details
Kansai Medical University Hospital ( Site 0804) Hirakata Osaka 573-1191 Japan Details
National Hospital Organization Kinki-chuo Chest Medical Center ( Site 0813) Sakai Osaka 591-8555 Japan Details
Shizuoka Cancer Center Hospital and Research Institute ( Site 0802) Sunto-gun Shizuoka 411-8777 Japan Details
National Hospital Organization Kyushu Medical Center ( Site 0805) Fukuoka 810-8563 Japan Details
Niigata Cancer Center Hospital ( Site 0808) Niigata 951-8566 Japan Details
Okayama University Hospital ( Site 0810) Okayama 700-8558 Japan Details
Osaka International Cancer Institute ( Site 0809) Osaka 541-8567 Japan Details
The Cancer Institute Hospital of JFCR ( Site 0800) Tokyo 135-8550 Japan Details
Chungbuk National University Hospital ( Site 1002) Cheongju si Chungbuk 28644 Korea, Republic of Details
National Cancer Center ( Site 1006) Goyang-si Kyonggi-do 10408 Korea, Republic of Details
The Catholic University of Korea St. Vincent s Hospital ( Site 1003) Suwon Kyonggi-do 16247 Korea, Republic of Details
Ajou University Hospital ( Site 1004) Suwon Kyonggi-do 16499 Korea, Republic of Details
Gyeongsang National University Hospital ( Site 1005) Jinju Kyongsangnam-do 52727 Korea, Republic of Details
Asan Medical Center ( Site 1007) Songpa-gu Seoul 05505 Korea, Republic of Details
Seoul National University Hospital ( Site 1000) Seoul 03080 Korea, Republic of Details
Korea University Guro Hospital ( Site 1008) Seoul 08308 Korea, Republic of Details
MidCentral DHB Palmerston North Hospital ( Site 1102) Palmerston North Manawatu-Wanganui 4414 New Zealand Details
Capital & Coast District Health Board - Wellington Hospital ( Site 1101) Wellington 6021 New Zealand Details
Wielospecjalistyczny Szpital SPZOZ w Zgorzelcu ( Site 2404) Zgorzelec Dolnoslaskie 59-900 Poland Details
Krakowski Szpital Specjalistyczny im Jana Pawla II ( Site 2420) Krakow Malopolskie 31-202 Poland Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Warszawa Mazowieckie 02-781 Poland Details
Szpital Rejonowy im. dr Jozefa Rostka ( Site 2402) Raciborz Slaskie 47-400 Poland Details
Samodzielny Publiczny Zespol Gruzlicy i Chorob Pluc ( Site 2417) Olsztyn Warminsko-mazurskie 10-357 Poland Details
Przychodnia Lekarska Komed ( Site 2416) Konin Wielkopolskie 62-500 Poland Details
MED-POLONIA Sp. z o.o. ( Site 2419) Poznan Wielkopolskie 60-693 Poland Details
Cardiomed SRL Cluj-Napoca ( Site 2504) Cluj Napoca Cluj 400015 Romania Details
S.C. Radiotherapy Center Cluj S.R.L ( Site 2507) Cluj-Napoca Cluj 407280 Romania Details
S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 2508) Craiova Dolj 200347 Romania Details
Policlinica Oncomed SRL ( Site 2505) Timisoara Timis 300239 Romania Details
Spitalul PDR Medlife ( Site 2509) Brasov 500152 Romania Details
S.C.Focus Lab Plus S.R.L ( Site 2502) Bucuresti 021389 Romania Details
Spitalul Clinic Judetean De Urgenta Constanta ( Site 2501) Constanta 900591 Romania Details
SBHI Leningrad Regional Clinical Hospital ( Site 2002) Saint Petersburg Leningradskaya Oblast 194291 Russian Federation Details
Moscow Regional Oncological Dispensary ( Site 2028) Balashikha Moskovskaya Oblast 143900 Russian Federation Details
Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 2000) Moscow Moskva 115478 Russian Federation Details
First Moscow State Medical University n.a. I.M.Sechenov ( Site 2024) Moscow Moskva 119991 Russian Federation Details
Moscow Research Oncology Institute named after P.A. Hertsen ( Site 2009) Moscow Moskva 125284 Russian Federation Details
FSAI Treatment and Rehabilitation Centre of the MoH and SD of RF ( Site 2006) Moscow Moskva 125367 Russian Federation Details
Nizhniy Novgorod Region Oncology Dispensary ( Site 2026) Nizhniy Novgorod Nizhegorodskaya Oblast 603081 Russian Federation Details
Budgetary Healthcare Institution of Omsk Region Clinical Oncology Dispensary-Chemotherapy #1 ( Site Omsk Omskaya Oblast 644013 Russian Federation Details
SBHI Samara Regional Clinical Oncology Dispensary ( Site 2016) Samara Samarskaya Oblast 443031 Russian Federation Details
SPb Central Clinical Railway Hospital ( Site 2003) Saint Petersburg Sankt-Peterburg 195271 Russian Federation Details
National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 2004) Saint Petersburg Sankt-Peterburg 197758 Russian Federation Details
SPb SBHI City Clinical Oncological Dispensary ( Site 2001) Saint Petersburg Sankt-Peterburg 198255 Russian Federation Details
Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 2021) Kazan Tatarstan, Respublika 420029 Russian Federation Details
Hospital Universitario Quiron Madrid ( Site 1701) Pozuelo de Alarcon Madrid 28223 Spain Details
Hospital Clinico Universitario de Valencia ( Site 1706) Valencia Valenciana, Comunitat 46010 Spain Details
Hospital del Mar ( Site 1702) Barcelona 08003 Spain Details
Hospital Universitario Nuestra Senora de Valme ( Site 1703) Sevilla 41014 Spain Details
Hospital Clinico Lozano Blesa ( Site 1700) Zaragoza 50009 Spain Details
Chang Gung Medical Foundation. Kaohsiung Branch ( Site 0907) Kaohsiung 833 Taiwan Details
China Medical University Hospital ( Site 0904) Taichung 40447 Taiwan Details
National Cheng Kung University Hospital ( Site 0905) Tainan 704 Taiwan Details
National Taiwan University Hospital ( Site 0900) Taipei 10048 Taiwan Details
Mackay Memorial Hospital ( Site 0902) Taipei 104 Taiwan Details
Chang Gung Medical Foundation.Linkou Branch ( Site 0903) Taoyuan 333 Taiwan Details
Namik Kemal Universitesi Tip Fakultesi ( Site 2100) Tekirdag Tekirdas 59100 Turkey Details
Baskent Unv. Adana Uyg. ve Arast. Hastanesi ( Site 2101) Adana 01120 Turkey Details
Gazi Universitesi Tip Fakultesi ( Site 2104) Ankara 06500 Turkey Details
Ankara Sehir Hastanesi ( Site 2105) Ankara 06800 Turkey Details
Bezmialem Vakif Univ. Tıp Fakultesi Hastanesi Tibbi Onkoloji Bolumu ( Site 2107) Istanbul 34093 Turkey Details
Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 2103) Istanbul 34722 Turkey Details
Ege Universitesi Tip Fakultesi ( Site 2109) Izmir 35040 Turkey Details
Erciyes Universitesi Tip Fakultesi ( Site 2108) Kayseri 38039 Turkey Details
Samsun Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi ( Site 2106) Samsun 55280 Turkey Details
Cherkasy Regional Oncology Dispensary ( Site 2211) Cherkasy Cherkaska Oblast 18009 Ukraine Details
City Clinical Hosp.4 of DCC ( Site 2201) Dnipro Dnipropetrovska Oblast 49102 Ukraine Details
MI Precarpathian Clinical Oncology Center ( Site 2204) Ivano-Frankivsk Ivano-Frankivska Oblast 76018 Ukraine Details
Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 2212) Kharkiv Kharkivska Oblast 61024 Ukraine Details
Regional Centre of Oncology-Thoracic organs ( Site 2205) Kharkiv Kharkivska Oblast 61070 Ukraine Details
PP PPC Acinus Medical and Diagnostic Centre ( Site 2209) Kropyvnitskiy Kirovohradska Oblast 25006 Ukraine Details
Medical Center Asklepion LLC ( Site 2234) Khodosivka Kyivska Oblast 08173 Ukraine Details
Medical and Diagnostic Centre LLC Dobryi Prognoz ( Site 2213) Kyiv Kyivska Oblast 03126 Ukraine Details
MI Odessa Regional Oncological Centre ( Site 2208) Odesa Odeska Oblast 65055 Ukraine Details
Central City Clinical Hospital ( Site 2207) Uzhgorod Zakarpatska Oblast 88000 Ukraine Details
Medical Center Verum ( Site 2230) Kyiv 03039 Ukraine Details
Kyiv City Clinical Oncology Centre ( Site 2210) Kyiv 03115 Ukraine Details
Barts Health NHS Trust - St Bartholomew s Hospital ( Site 1923) London London, City Of EC1M 6BQ United Kingdom Details
Chelsea and Westminster Hospital ( Site 1901) London London, City Of SW10 9NH United Kingdom Details
West Suffolk Hospitals NHS Trust ( Site 1919) Bury Saint Edmunds Suffolk IP33 2QZ United Kingdom Details
Colchester General Hospital ( Site 1911) Colchester Worcestershire CO4 5JL United Kingdom Details
Birmingham Heartlands Hospital ( Site 1910) Birmingham B9 5SS United Kingdom Details
Western General Hospital, Edinburgh ( Site 1924) Edinburg EH4 2XU United Kingdom Details
Singleton Hospital ( Site 1909) Swansea SA2 8QA United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field