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| NCT ID | NCT04102098 |
| Title | A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation (IMbrave050) |
| Acronym | IMbrave050 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NZL | NLD | ITA | FRA | ESP | DEU | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Kaiser Permanente Los Angeles | Los Angeles | California | 90027 | United States | Details | |
| Mercy Medical Center | Baltimore | Maryland | 21202 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| The University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Swedish Cancer Inst. | Seattle | Washington | 98104 | United States | Details | |
| St Vincent's Hospital Sydney | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| Riverina Cancer Care Centre | Wagga Wagga | New South Wales | 2650 | Australia | Details | |
| Lkh-Univ. Klinikum Graz | Graz | 8036 | Austria | Details | ||
| Klinikum Klagenfurt am Wörtersee; Abt.Gastroenterologie&Hepatologie,Endokrinologie | Klagenfurt | 9020 | Austria | Details | ||
| Medizinische Universität Wien; Univ.Klinik für Innere Medizin III - Gastroenterologie & Hepatologie | Wien | 1090 | Austria | Details | ||
| Imeldaziekenhuis | Bonheiden | 2820 | Belgium | Details | ||
| AZ Delta (Campus Rumbeke) | Roeselare | 8800 | Belgium | Details | ||
| Hospital Sao Rafael - HSR | Salvador | BA | 41253-190 | Brazil | Details | |
| Sociedade beneficente de senhoras Hospital Sirio Libanes | Brasilia | DF | 70200-730 | Brazil | Details | |
| Hospital do Cancer UOPECCAN; Pesquisa Clínica | Cascavel | PR | 85806-300 | Brazil | Details | |
| Hospital das Clinicas - UFRGS | Porto Alegre | RS | 90035-903 | Brazil | Details | |
| Hospital Alemao Oswaldo Cruz; Oncologia | Sao Paulo | SP | 01327-001 | Brazil | Details | |
| Gordon & Leslie Diamond Health Care Centre | Vancouver | British Columbia | V5Z 1M9 | Canada | Details | |
| McGill University Health Centre - Glen Site | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Peking Union Medical College Hospital | Beijing City | 100032 | China | Details | ||
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| Affiliated Hospital of Bengbu Medical College | Bengbu | 233004 | China | Details | ||
| The First Hospital of Jilin University | Changchun City | 130021 | China | Details | ||
| West China Hospital, Sichuan University | Chengdu | 610041 | China | Details | ||
| Daping Hospital of Third Military Medical University | Chongqing | 400042 | China | Details | ||
| The Second Affiliated Hospital of Dalian Medical University | Dalian | 116027 | China | Details | ||
| Mengchao Hepatobiliary Hospital Of Fujian Medical University | Fuzhou City | 350025 | China | Details | ||
| Fujian Cancer Hospital | Fuzhou | 350014 | China | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou City | 510663 | China | Details | ||
| Cancer Center of Guangzhou Medical University | Guangzhou | 510000 | China | Details | ||
| Zhujiang Hospital, Southern Medical University | Guangzhou | 510280 | China | Details | ||
| Nanfang Hospital, Southern Medical University | Guangzhou | 510515 | China | Details | ||
| Zhejiang Cancer Hospital; Zhejiang Cancer Hospital cancer department | Hangzhou City | 310022 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Anhui Province Cancer Hospital | Hefei City | 230031 | China | Details | ||
| Anhui Provincial Hospital | Hefei | 230001 | China | Details | ||
| The Second Affiliated Hospital of Anhui Medical University | Hefei | 230601 | China | Details | ||
| Shandong Cancer Hospital | Jinan | 250117 | China | Details | ||
| The 81st Hospital of P.L.A. | Nanjing City | 210002 | China | Details | ||
| Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School | Nanjing City | 210008 | China | Details | ||
| Zhongda Hospital Affiliated to Southeast University | Nanjing | 210009 | China | Details | ||
| Guangxi Cancer Hospital of Guangxi Medical University | Nanning City | 530021 | China | Details | ||
| The First Affiliate Hospital of Guangxi Medical University | Nanning | 530021 | China | Details | ||
| Zhongshan Hospital Fudan Unvierstiy | Shanghai City | 200032 | China | Details | ||
| Huashan Hospital Affiliated to Fudan University | Shanghai City | 200040 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai City | 200120 | China | Details | ||
| Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine | Shanghai | 200127 | China | Details | ||
| The First Affiliated Hospital of China Medical University | Shenyang City | 110001 | China | Details | ||
| Shengjing Hospital of China Medical University | ShenYang | 110004 | China | Details | ||
| Tianjin Cancer Hospital | Tianjin | 300060 | China | Details | ||
| The Tumor Hospital of Xinjiang Medical University | Urumqi | 830000 | China | Details | ||
| Wuhan Union Hospital Tongji Medical College, Huazhong University of Science and Technology | Wuhan City | 430022 | China | Details | ||
| Renmin Hospital of Wuhan University | Wuhan | 430060 | China | Details | ||
| Zhongnan Hospital of Wuhan University | Wuhan | 430071 | China | Details | ||
| Hubei Cancer Hospital | Wuhan | 430079 | China | Details | ||
| Northern Jangsu People's Hospital | Yangzhou City | 225001 | China | Details | ||
| Clinica CIMCA | San José | 10103 | Costa Rica | Details | ||
| Fakultni nemocnice Brno; Interni hematologicka a onkologicka klinika | Brno | 625 00 | Czechia | Details | ||
| Fakultni Thomayerova Nemocnice; Onkologicke Oddeleni | Praha | 140 59 | Czechia | Details | ||
| Hopital Jean Minoz; Oncologie | Besancon | 25030 | France | Details | ||
| Hôpital Avicenne - Groupement Hospitalier Universitaire Paris Seine St Denis; Service d'Hépatologie | Bobigny Cedex | 93009 | France | Details | ||
| Hôpital Albert Michallon | La Tronche | 38700 | France | Details | ||
| Fondation Hopital Saint Joseph; Gastro-Enterologie | Marseille | 13285 | France | Details | ||
| CHU Bordeaux - Hôpital Haut-Lévêque; Service d?Hépato-Gastroentérologie et d Oncologie digestive | Pessac | 33604 | France | Details | ||
| Hopital Robert Debre; Gastro Enterologie | Reims | 51092 | France | Details | ||
| Hopital de Pontchaillou; Service Hepato Gastro Enterologie | Rennes | 35033 | France | Details | ||
| CHU de Toulouse - Hôpital Rangueil | Toulouse Cedex 09 | 31059 | France | Details | ||
| Hopitaux de Brabois - Gastro-Entereologie | Vandoeuvre-les-nancy | 54511 | France | Details | ||
| Universitätsklinikum Bonn, Medizinische Klinik und Poliklinik I.; Onkologische Gastroenterologie | Bonn | 53127 | Germany | Details | ||
| Klinik Johann Wolfgang von Goethe Uni; Zentrum der Inneren Medizin; Medizinische Klinik I | Frankfurt | 60590 | Germany | Details | ||
| Klinikum der Uni Regensburg; Klinik f.Innere Medizin I Abt. Hämatologie und Internistische Onkologie | Regensburg | 93053 | Germany | Details | ||
| Universitätsklinikum Ulm; Zentrum für Innere Medizin Klinik für Innere Medizin I | Ulm | 89081 | Germany | Details | ||
| Queen Mary Hospital; Dept. Of Haematology & Oncology | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hospital; Department of Clinical Onocology | Shatin | Hong Kong | Details | |||
| Ospedale Regionale Di Parma; Divisione Di Oncologia Medica | Parma | Emilia-Romagna | 43100 | Italy | Details | |
| Ospedale Maggiore Policlinico; U.O.C. di Oncologia Medica | Milano | Lombardia | 20122 | Italy | Details | |
| Asst Santi Paolo E Carlo | Milano | Lombardia | 20142 | Italy | Details | |
| Azlenda Ospendaliero-Universitaria Pisana; C.O. Oncologia 2 | Pisa | Toscana | 56100 | Italy | Details | |
| Chiba University Hospital | Chiba | 260-8677 | Japan | Details | ||
| Ehime Prefectural Central Hospital | Ehime | 790-0024 | Japan | Details | ||
| Hiroshima University Hospital | Hiroshima | 734-8551 | Japan | Details | ||
| Sapporo Kosei Genaral Hospital | Hokkaido | 060-0033 | Japan | Details | ||
| Hyogo Medical University Hospital | Hyogo | 663-8501 | Japan | Details | ||
| Japanese Red Cross Society Himeji Hospital | Hyogo | 670-8540 | Japan | Details | ||
| Kanazawa University Hospital | Ishikawa | 920-8641 | Japan | Details | ||
| Yokohama City University Medical Center | Kanagawa | 232-0024 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
| Kitasato University Hospital | Kanagawa | 252-0375 | Japan | Details | ||
| Kumamoto University Hospital | Kumamoto | 860-8556 | Japan | Details | ||
| Osaka Red Cross Hospital | Osaka | 543-8555 | Japan | Details | ||
| Kindai University Hospital | Osaka | 589-8511 | Japan | Details | ||
| Tokushima University Hospital | Tokushima | 770-8503 | Japan | Details | ||
| Toranomon Hospital | Tokyo | 105-8470 | Japan | Details | ||
| The University of Tokyo Hospital | Tokyo | 113-8655 | Japan | Details | ||
| Japanese Red Cross Musashino Hospital | Tokyo | 180-8610 | Japan | Details | ||
| Pusan National University Hospital | Busan | 602-739 | Korea, Republic of | Details | ||
| Kyungpook National University Hospital | Daegu | 41944 | Korea, Republic of | Details | ||
| CHA Bundang Medical Center | Gyeonggi-do | 13496 | Korea, Republic of | Details | ||
| Ajou University Medical Center | Gyeonggi-do | 16499 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 463-707 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Gangnam Severance Hospital | Seoul | 06273 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Seoul St Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| Borame Medical Center | Seoul | 07061 | Korea, Republic of | Details | ||
| Ulsan University Hosiptal | Ulsan | 44033 | Korea, Republic of | Details | ||
| Centro Medico Dalinde | Cdmx | Mexico CITY (federal District) | 06760 | Mexico | Details | |
| Filios Alta Medicina | Monterrey | Nuevo LEON | 64460 | Mexico | Details | |
| Oaxaca Site Management Organization | Oaxaca de Juárez | Oaxaca | 68000 | Mexico | Details | |
| Maastricht University Medical Center | Maastricht | 6229 HX | Netherlands | Details | ||
| Auckland City Hospital | Auckland | 1023 | New Zealand | Details | ||
| Clínica San Gabriel; Unidad de Investigación Oncológica de la Clínica San Gabriel | Lima | 15088 | Peru | Details | ||
| Instituto Nacional de Enfermedades Neoplasicas | Lima | Lima 34 | Peru | Details | ||
| Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie; Klinika Onkologii i Radioterapii, | Warszawa | 02-781 | Poland | Details | ||
| First Moscow State Medical University n.a. I.M. Sechenov | Moscow | Moskovskaja Oblast | 119991 | Russian Federation | Details | |
| Group of companies "Medci" | Moskva | Moskovskaja Oblast | 105229 | Russian Federation | Details | |
| Clinical hospital #1, FBHI Volga district medical center, Federal Medical and Biological Agency | Nizhny Novgorod | Niznij Novgorod | 603109 | Russian Federation | Details | |
| Russian Scientific Center of Radiology and Surgical Technologies; Dept of Radiology | Pesochny | Sankt Petersburg | 197758 | Russian Federation | Details | |
| National Cancer Centre | Singapore | 169610 | Singapore | Details | ||
| Tan Tock Seng Hospital; Oncology | Singapore | 308433 | Singapore | Details | ||
| Hospital Universitario Puerta de Hierro | Majadahonda | Madrid | 28222 | Spain | Details | |
| Hospital Universitario Infanta Cristina; Servicio de Oncologia | Badajoz | 06080 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon; Servicio de Oncologia | Madrid | 28007 | Spain | Details | ||
| Changhua Christian Hospital | Chang Hua | 500 | Taiwan | Details | ||
| Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung City | 807 | Taiwan | Details | ||
| National Taiwan Uni Hospital; Dept of Oncology | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital; Gastroenterology Division | Taipei | 112 | Taiwan | Details | ||
| Chang Gung Medical Foundation - Linkou; Dept. of Hepato-Gastroenterology | Taoyuan | 333 | Taiwan | Details | ||
| Rajavithi Hospital; Division of Medical Oncology | Bangkok | 10400 | Thailand | Details | ||
| Siriraj Hospital; Medical Oncology Unit | Bangkok | 10700 | Thailand | Details | ||
| Chiang Rai Prachanukroh Hospital; Department Of Medicine | Chiang Rai | 57000 | Thailand | Details | ||
| Chulabhorn Hospital; Medical Oncology | Lak Si | 10210 | Thailand | Details | ||
| Adana Baskent University Hospital; Medical Oncology | Adana | 01120 | Turkey | Details |