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| NCT ID | NCT04127110 |
| Title | Activity of Lorlatinib Based on ALK Resistance Mutations Detected on Blood in ALK Positive NSCLC Patients (ALKALINE) |
| Acronym | ALKALINE |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | European Organisation for Research and Treatment of Cancer - EORTC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | NLD | GBR | FRA | ESP | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Institut Jules Bordet-Hopital Universitaire ULB | Brussels | 1000 | Belgium | Details | ||
| Cliniques Universitaires Saint-Luc | Brussels | BE 1200 | Belgium | Details | ||
| Universitair Ziekenhuis Antwerpen | Edegem | BE 2650 | Belgium | Details | ||
| CHU-UCL Namur - CHU Mont Godinne - UCL Namur | Yvoir | 5530 | Belgium | Details | ||
| Centre Hospitalier Avignon | Avignon | 84902 | France | Details | ||
| Assistance Publique Hopitaux Paris - Hopital Avicenne | Bobigny | France | Details | |||
| CHU de Brest | Brest | 29200 | France | Details | ||
| Centre Hopitalier Intercommunal De Creteil | Créteil | 94010 | France | Details | ||
| Gustave Roussy | Villejuif | France | Details | |||
| King Hussein Cancer Center | Amman | Jordan | Details | |||
| The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis | Amsterdam | 1066 CX | Netherlands | Details | ||
| Academisch Ziekenhuis Maastricht | Maastricht | Netherlands | Details | |||
| Erasmus MC | Rotterdam | Netherlands | Details | |||
| Oslo University Hospital - Radiumhospitalet | Oslo | Norway | Details | |||
| Institut Catala d'Oncologia - ICO L'Hospitalet - Hospital Duran i Reynals | Hospitalet De Llobregat | Barcelona | 08908 | Spain | Details | |
| Hospital Clinic Universitari de Barcelona | Barcelona | Spain | Details | |||
| Hospital De La Santa Creu I Sant Pau | Barcelona | Spain | Details | |||
| Institut Catala d'Oncologia - ICO Badalona - Hospital Germans Trias i Pujol | Barcelona | Spain | Details | |||
| Hospital General Universitario Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| Clinica Universidad de Navarra - Clinica Universitaria De Navarra | Madrid | Spain | Details | |||
| Hospital Universitario 12 De Octubre | Madrid | Spain | Details | |||
| Hospital Universitario Ramon y Cajal | Madrid | Spain | Details | |||
| Hospital Universitari Son Espases | Palma De Mallorca | Spain | Details | |||
| Clinica Universidad de Navarra - Clinica Universitaria De Navarra | Pamplona | Spain | Details | |||
| University Hospital Virgen del Rocio | Sevilla | Spain | Details | |||
| The Christie NHS Foundation Trust | Manchester | United Kingdom | Details |