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| NCT ID | NCT04154189 |
| Title | A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Eisai Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | child |
| Covered Countries | USA | NZL | NLD | ITA | GBR | FRA | ESP | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Children's of Alabama | Birmingham | Alabama | 35233 | United States | Details | |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | United States | Details | |
| Children's Hospital of Orange County | Orange | California | 92868 | United States | Details | |
| UCSF Benioff Children's Hospitals | San Francisco | California | 94143 | United States | Details | |
| Childrens Hospital Colorado | Aurora | Colorado | 80045 | United States | Details | |
| Children's National Medical Center | Washington | District of Columbia | 20010 | United States | Details | |
| Riley Hospital For Children | Indianapolis | Indiana | 46202 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | United States | Details | |
| Children's Medical Center Dallas | Dallas | Texas | 75235 | United States | Details | |
| Cook Children's Health Care System | Fort Worth | Texas | 76104 | United States | Details | |
| Texas Children's Hospital | Houston | Texas | 77030 | United States | Details | |
| Chris O'Brien Lifehouse Hospital | Camperdown | Australia | Details | |||
| Perth Childrens Hospital | Nedlands | Australia | Details | |||
| Royal Children's Hospital Melbourne | Parkville | Australia | Details | |||
| Queensland Children's Hospital | South Brisbane | Australia | Details | |||
| Children's Hospital at Westmead | Westmead | Australia | Details | |||
| St. Anna Kinderspital | Wien | Austria | Details | |||
| UZ Gent | Gent | Belgium | Details | |||
| Hospital For Sick Children | Toronto | Canada | Details | |||
| FN Brno 2 Detska Klinika | Brno | Czechia | Details | |||
| Fakultní nemocnice v Motole | Prague | Czechia | Details | |||
| Tampereen yliopistollinen sairaala | Tampere | Länsi-Suomen Lääni | FI-33520 | Finland | Details | |
| Centre Hospitalier Universitaire de Bordeaux, Hopital Pellegrin | Bordeaux | France | Details | |||
| Centre Oscar Lambret | Lille | France | Details | |||
| Centre Léon Berard | Lyon | France | Details | |||
| Hopitaux de La Timone | Marseille | France | Details | |||
| Hôpital de La Mère Et de L'enfant | Nantes | France | Details | |||
| CHU de Nice | Nice | France | Details | |||
| Hôpital Armand Trousseau | Paris | France | Details | |||
| Institut Curie | Paris | France | Details | |||
| Hopital de Hautepierre | Strasbourg | France | Details | |||
| Hôpital Des Enfants | Toulouse | France | Details | |||
| CHRU Nancy | Vandœuvre-lès-Nancy | France | Details | |||
| Institut Gustave Roussy | Villejuif | France | Details | |||
| Hong Kong Children's Hospital | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hospital | Hong Kong | Hong Kong | Details | |||
| Children's Health Ireland at Crumlin | Dublin | Ireland | Details | |||
| Schneider Children's Medical Center of Israel | Petach Tikva | Israel | Details | |||
| Istituti Ortopedici Rizzoli | Bologna | Italy | Details | |||
| Azienda Ospedaliera A Meyer | Firenze | Italy | Details | |||
| Istituto Giannina Gaslini | Genova | Italy | Details | |||
| Istituto Nazionale Dei Tumori | Milan | Italy | Details | |||
| IRCCS Ospedale Pediatrico Bambino Gesù | Roma | Italy | Details | |||
| National Cancer Center | Goyang-si | Korea, Republic of | Details | |||
| Asan Medical Center | Seoul | Korea, Republic of | Details | |||
| Samsung Medical Center | Seoul | Korea, Republic of | Details | |||
| Seoul National University Hospital | Seoul | Korea, Republic of | Details | |||
| Severance Hospital Yonsei University Health System | Seoul | Korea, Republic of | Details | |||
| Princess Maxima Center for Pediatric Oncology | Utrecht | Netherlands | Details | |||
| Auckland City Hospital | Auckland | New Zealand | Details | |||
| Starship Children's Hospital | Auckland | New Zealand | Details | |||
| KK Women's and Children's Hospital | Singapore | Singapore | Details | |||
| National Cancer Centre | Singapore | Singapore | Details | |||
| National University Hospital | Singapore | Singapore | Details | |||
| Hospital Universitario de Cruces | Barakaldo | Spain | Details | |||
| Hospital Sant Joan de Deu | Barcelona | Spain | Details | |||
| Hospital Universitario Vall d'Hebrón | Barcelona | Spain | Details | |||
| Hospital Infantil Universitario Niño Jesus | Madrid | Spain | Details | |||
| Hospital Universitario Fundacion Jimenez Diaz | Madrid | Spain | Details | |||
| Hospital Universitario La Paz | Madrid | Spain | Details | |||
| Hospital Universitario Virgen del Rocio | Sevilla | Spain | Details | |||
| Hospital Universitari i Politecnic La Fe de Valencia | Valencia | Spain | Details | |||
| Drottning Silvias Barn Och Ungdomssjukhus | Göteborg | Sweden | Details | |||
| Skanes Universitetssjukhus Lund | Lund | Sweden | Details | |||
| Karolinska Universitetssjukhuset Solna | Stockholm | Sweden | Details | |||
| Centre Hospitalier Universitaire Vaudois | Lausanne | Switzerland | Details | |||
| Kinderspital Zürich - Eleonorenstiftung | Zürich | Switzerland | Details | |||
| National Taiwan University Hospital | Taipei | Taiwan | Details | |||
| Taipei Veterans General Hospital | Taipei | Taiwan | Details | |||
| Birmingham Children's Hospital | Birmingham | United Kingdom | Details | |||
| The Royal Hospital for Children | Bristol | United Kingdom | Details | |||
| Royal Hospital for Children | Glasgow | United Kingdom | Details | |||
| Leeds Children Hospital | Leeds | United Kingdom | Details | |||
| Alder Hey Children's Hospital | Liverpool | United Kingdom | Details | |||
| UCL Cancer Institute | London | United Kingdom | Details | |||
| Royal Manchester Childrens Hospital | Manchester | United Kingdom | Details | |||
| The Christie NHS Foundation Trust | Manchester | United Kingdom | Details | |||
| Royal Victoria Infirmary | Newcastle | United Kingdom | Details | |||
| John Radcliffe Hospital | Oxford | United Kingdom | Details |