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| NCT ID | NCT04181827 |
| Title | A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma (CARTITUDE-4) |
| Acronym | CARTITUDE-4 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Janssen Research & Development, LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | United States | Details | |
| Mayo Clinic Cancer Center-Scottsdale | Phoenix | Arizona | 85054 | United States | Details | |
| Stanford University Medical Center | Stanford | California | 94305-5623 | United States | Details | |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | United States | Details | |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | United States | Details | |
| University of Miami Leonard M. Miller School of Medicine - SCCC | Miami | Florida | 33136 | United States | Details | |
| University of Iowa Hospitals & Clinics | Iowa City | Iowa | 52242 | United States | Details | |
| University of Kansas | Westwood | Kansas | 66205 | United States | Details | |
| University Of Maryland Medical Center | Baltimore | Maryland | 21201 | United States | Details | |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| University of Rochester Medical Center | Rochester | New York | 14642 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| The Ohio State University | Columbus | Ohio | 43210 | United States | Details | |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | United States | Details | |
| Wisconsin Institutes for Medical Research | Madison | Wisconsin | 53705 | United States | Details | |
| Medical College Of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
| Royal Adelaide Hospital | Adelaide | 5000 | Australia | Details | ||
| Royal Prince Alfred Hospital | Camperdown | 2050 | Australia | Details | ||
| Royal Brisbane and Womens Hospital | Herston | 4029 | Australia | Details | ||
| Peter MacCallum Cancer Centre | Melbourne | 3000 | Australia | Details | ||
| Alfred Health | Melbourne | 3004 | Australia | Details | ||
| Fiona Stanley Hospital | Murdoch | 6150 | Australia | Details | ||
| Universitair Ziekenhuis - Antwerpen | Antwerp | 2650 | Belgium | Details | ||
| UZ Gent | Gent | 9000 | Belgium | Details | ||
| UZ Leuven | Leuven | 3000 | Belgium | Details | ||
| Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman | Liege | B-4000 | Belgium | Details | ||
| Rigshospitalet | Copenhagen | 2100 | Denmark | Details | ||
| CHRU de Lille - Hopital Claude Huriez | LILLE Cedex | 59037 | France | Details | ||
| CHU de Montpellier, Hopital Saint-Eloi | Montpellier | 34295 | France | Details | ||
| C.H.U. Hotel Dieu - France | Nantes | 44093 | France | Details | ||
| Hopital Saint Louis | Paris cedex 10 | 75475 | France | Details | ||
| Centre hospitalier Lyon-Sud | Pierre Benite cedex | 69495 | France | Details | ||
| CHU De Poitiers | Poitiers | 86021 | France | Details | ||
| Institut Universitaire du cancer de Toulouse-Oncopole | Toulouse cedex 9 | 31059 | France | Details | ||
| Universitatsklinikum Carl Gustvav Carus Dresden an der Technischen Universitat Dresden | Dresden | 01307 | Germany | Details | ||
| Universitaetsklinikum Hamburg Eppendorf | Hamburg | 20246 | Germany | Details | ||
| Universitaetsklinikum Koeln | Koeln | 50924 | Germany | Details | ||
| Universitaetsklinikum Leipzig | Leipzig | 04103 | Germany | Details | ||
| Klinikum der Eberhard Karls Universitaet Abt fur innere Med II Haematologie Onkologie Germany | Tubingen | 72076 | Germany | Details | ||
| Universitatsklinikum Wurzburg | Wuerzburg | 97080 | Germany | Details | ||
| Attikon University General Hospital of Attica | Athens | 12462 | Greece | Details | ||
| Hadassah University Hospita - Ein Kerem | Jerusalem | P.O.B. 12000 | Israel | Details | ||
| Sheba Medical Center | Ramat Gan | 74047 | Israel | Details | ||
| Sourasky Medical Center | Tel-Aviv | 64239 | Israel | Details | ||
| Azienda Opedaliero-Universitaria Policlinico Sant'orsola Malpighi di Bologna | Bologna | 40138 | Italy | Details | ||
| IRCCS Ospedale San Raffaele HSR | Milano | 20132 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | 20133 | Italy | Details | ||
| Policlinico Universitario Agostino Gemelli | Roma | 00168 | Italy | Details | ||
| A.O.U. Citta della Salute e della Scienza di Torino - Presidio Molinette | Turin | 10126 | Italy | Details | ||
| Kyushu University Hospital | Fukuoka | 812-8582 | Japan | Details | ||
| Kanazawa University Hospital | Kanazawa | 920-8641 | Japan | Details | ||
| University Hospital Kyoto Perfectural University of Medicine | Kyoto | 602-8566 | Japan | Details | ||
| Nagoya City University Hospital | Nagoya | 467 8602 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| Hokkaido University Hospital | Sapporo | 060-8648 | Japan | Details | ||
| Tohoku University Hospital | Sendai | 980-8574 | Japan | Details | ||
| Japanese Red Cross Medical Center | Shibuya | 150-8935 | Japan | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea Seoul St. Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| VU Medisch Centrum | Amsterdam | 1081 HV | Netherlands | Details | ||
| University Medical Center Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| Erasmus MC | Rotterdam | 3015 CN | Netherlands | Details | ||
| UMC Utrecht | Utrecht | 3584 CX | Netherlands | Details | ||
| Uniwersyteckie Centrum Kliniczne | Gdansk | 80-214 | Poland | Details | ||
| Narodowy Instytut Onkologii im.Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz. w Gliwicach | Gliwice | 44102 | Poland | Details | ||
| Uniwersytecki Szpital Kliniczny w Poznaniu | Poznan | 60-569 | Poland | Details | ||
| Instytut Hematologii i Transfuzjologii | Warszawa | 02-776 | Poland | Details | ||
| Inst. Cat. D'Oncologia-Badalona | Badalona | 08916 | Spain | Details | ||
| Hosp. Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hosp. Gral. Univ. Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| Hosp. Univ. 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Clinica Univ. de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hosp. Clinico Univ. de Salamanca | Salamanca | 37007 | Spain | Details | ||
| Hosp. Virgen Del Rocio | Sevilla | 41013 | Spain | Details | ||
| Skane University Hospital | Lund | 221 85 | Sweden | Details | ||
| Karolinska Universitetssjukhuset Huddinge, Hematologiska Kliniken, Huddinge | Stockholm | 141 86 | Sweden | Details | ||
| Akademiska Sjukhuset | Uppsala | 751 85 | Sweden | Details | ||
| Queen Elizabeth Hospital | Birmingham | B15 2TH | United Kingdom | Details | ||
| Bristol Haematology and Oncology Centre | Bristol | BS2 8ED | United Kingdom | Details | ||
| University Hospital Wales | Cardiff | CF14 4XW | United Kingdom | Details | ||
| University College Hospital | London | NW1 2BU | United Kingdom | Details | ||
| King's College Hospital | London | SE5 9RS | United Kingdom | Details | ||
| Christie Hospital | Manchester | M20 4BX | United Kingdom | Details | ||
| Freeman Hospital | Newcastle Upon Tyne | NE7 7DN | United Kingdom | Details |