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NCT ID NCT04182204
Title A Study to Evaluate the Safety and Efficacy of Polatuzumab Vedotin in Combination With Rituximab, Gemcitabine and Oxaliplatin Compared to Rituximab, Gemcitabine and Oxaliplatin Alone in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Hoffmann-La Roche
Indications

diffuse large B-cell lymphoma

Therapies

Gemcitabine + Oxaliplatin + Rituximab

Gemcitabine + Oxaliplatin + Polatuzumab vedotin-piiq + Rituximab

Age Groups: senior | adult
Covered Countries USA | ITA | FRA | ESP | DEU | CAN

Facility Status City State Zip Country Details
Memorial Regional Hospital Completed Hollywood Florida 33021 United States Details
Cancer Specialists; North Florida ;Jacksonville (AC Skinner Pkwy) Recruiting Jacksonville Florida 32256 United States Details
Memorial Cancer Institute at Memorial West Recruiting Pembroke Pines Florida 33028 United States Details
Oncology Hematology Associates - Springfield Recruiting Springfield Missouri 65807 United States Details
Nebraska Cancer Specialists; Oncology Hematology West, PC Recruiting Omaha Nebraska 68130 United States Details
MSKCC at Basking Ridge Recruiting Basking Ridge New Jersey 07920 United States Details
Memorial Sloan Kettering - Monmouth Recruiting Middletown New Jersey 07748 United States Details
Memorial Sloan Kettering Cancer Center at Bergen Active, not recruiting Montvale New Jersey 07645 United States Details
MSKCC @ Commack Recruiting Commack New York 11725 United States Details
The Cancer Institute at St Francis Hospital Withdrawn East Hills New York 11548 United States Details
Memorial Sloan Kettering Cancer Center at Westchester Recruiting Harrison New York 10604 United States Details
Memorial Sloan-Kettering Cancer Center Recruiting New York New York 10065 United States Details
Memorial Sloan Kettering Nassau Recruiting Uniondale New York 11553 United States Details
Baptist Memorial Hospital Withdrawn Memphis Tennessee 38120 United States Details
Millennium Research & Clinical Development Recruiting Houston Texas 77090 United States Details
Hospital Sao Rafael - HSR Recruiting Salvador BA 41253-190 Brazil Details
Liga Norte Riograndense Contra O Câncer Recruiting Natal RN 59040150 Brazil Details
Hospital das Clinicas - UFRGS Recruiting Porto Alegre RS 90035-903 Brazil Details
Hospital das Clinicas - FMUSP Recruiting Sao Paulo SP 05403-900 Brazil Details
London Health Sciences Centre Recruiting London Ontario N6A 4L6 Canada Details
Niagara Health Systems - St. Catherines General Site; Niagara Health System-St. Catharines Site Recruiting St. Catharines Ontario L2R 7C6 Canada Details
McGill University Health Centre - Glen Site Recruiting Montreal Quebec H4A 3J1 Canada Details
Centre hospitalier regional de Trois-Rivieres Recruiting Trois-Rivieres Quebec G8Z 3R9 Canada Details
Hu Nan Provincial Cancer Hospital Recruiting Changsha 410006 China Details
West China Hospital - Sichuan University Recruiting Chengdu City 610047 China Details
Cancer Center, Sun Yat-sen University of Medical Sciences; Department of Medical Oncology Recruiting Guangzhou City 510060 China Details
Zhujiang Hospital, Southern Medical University Recruiting Guangzhou 510280 China Details
The 1st Affiliated Hospital of Nanchang Unversity Recruiting Nanchang 330019 China Details
Guangxi Cancer Hospital of Guangxi Medical University Active, not recruiting Nanning 530021 China Details
Institute of Hematology and Hospital of Blood Disease Recruiting Tianjin City 300020 China Details
Union Hospital Tongji Medical College Huazhong University of Science and Technology Recruiting Wuhan City 430023 China Details
First Affiliated Hospital of Medical College of Xi'an Jiaotong University Recruiting Xi'an 710061 China Details
Helsinki University Central Hospital; Dept of Oncology Withdrawn Helsinki 00250 Finland Details
Kuopio Uni Hospital; Oncology Dept Withdrawn Kuopio 70211 Finland Details
Oulu University Hospital; Oncology Recruiting Oulu 90029 Finland Details
Tampere University Hospital; Dept of Oncology Recruiting Tampere 33520 Finland Details
Hopital Henri Mondor; 51 Av Mal Lattre De Tassigny Recruiting Creteil 94010 France Details
CHU de Nîmes - Hôpital Carémeau Recruiting Nimes 30029 France Details
Centre Henri Becquerel; Service Hématologie Recruiting Rouen 76038 France Details
ICANS Recruiting Strasbourg 67200 France Details
Hopital Bretonneau; Hematologie Therapie Cellulaire Recruiting TOURS Cedex 37044 France Details
Universitätsklinikum Ulm; Medizinische Uni-Klinik III Abt. Innere Medizin III Hämatologie u. Onkolo. Recruiting Ulm 89081 Germany Details
Laiko General Hospital; Hematology Clinic Recruiting Athens 115 27 Greece Details
Attiko Hospital; Haematology Clinic Recruiting Athens 124 62 Greece Details
All India Institute of Medical Sciences ,Institute Rotary Cancer Hospital; Department of Oncology Recruiting New Delhi 110029 India Details
Cork University Hospital Withdrawn Cork Ireland Details
St James' Hospital; Cancer Clinical Trials Office Active, not recruiting Dublin Ireland Details
Azienda Ospedaliero-Universitaria Policlinico di Modena Ematologia Recruiting Modena Emilia-Romagna 41123 Italy Details
Az. Osp. Uni Ria Policlinico Tor Vergata; Unita Di Ematologia Recruiting Roma Lazio 00133 Italy Details
Osp. San Raffaele; Dip. Di Oncoematologia Recruiting Milano Lombardia 20132 Italy Details
Uni Degli Studi Di Bari, Policlinico; Cattedra Di Ematologia,Dipart. Di Medicina Interna E Publica Recruiting Bari Puglia 70124 Italy Details
ARNAS Garibaldi; Ematologia Withdrawn Catania Sicilia 95122 Italy Details
USL 4 di Prato - Nuovo Ospeale di Prato Recruiting Prato Toscana 59100 Italy Details
Ematologia/immunologia Clinica Azienda Ospedaliera Policlinico di Padova Recruiting Padova Veneto 35128 Italy Details
Pusan National University Hospital Recruiting Busan 49241 Korea, Republic of Details
Chungnam National University Hospital Recruiting Daejeon 35015 Korea, Republic of Details
Seoul National University Bundang Hospital Recruiting Seongnam-si 13605 Korea, Republic of Details
Severance Hospital, Yonsei University Health System Active, not recruiting Seoul 03722 Korea, Republic of Details
Health Pharma Professional Research Recruiting Cdmx Mexico CITY (federal District) 03100 Mexico Details
Instituto Nacional de Cancerologia; Oncology Recruiting Distrito Federal 14080 Mexico Details
Hospital de Especialidades Centro Medico Nacional La Raza; Haematology Recruiting Mexico City 02990 Mexico Details
Hospital Universitari Germans Trias i Pujol; Servicio de Hematologia Recruiting Badalona Barcelona 08915 Spain Details
Hospital Universitario de Canarias;servicio de Hematologia Recruiting La Laguna Tenerife 38320 Spain Details
Hospital Univ. 12 de Octubre; Servicio de Hematologia Recruiting Madrid 28041 Spain Details
Hospital Clinico Universitario de Salamanca;Servicio de Hematologia Active, not recruiting Salamanca 37007 Spain Details
Hospital Universitario Dr. Peset; Servicio de Hematologia Active, not recruiting Valencia 46017 Spain Details
Akademiska sjukhuset, Onkologkliniken Recruiting Uppsala 751 85 Sweden Details
Sakarya Universitesi Egitim ve Arastirma Hastanesi Recruiting Adapazari/Sakarya 54100 Turkey Details
Abdurrahman Yurtarslan Onkoloji Training and Research Hospital Recruiting Ankara 06200 Turkey Details
Akdeniz Uni School of Medicine; Hematology Recruiting Antalya 07059 Turkey Details
Istanbul Uni Istanbul Medical Faculty Recruiting Istanbul 34093 Turkey Details
Istanbul University Cerrahpasa Medical Faculty; Hematology Department Recruiting Istanbul 34098 Turkey Details
Kocaeli Universitesi Tip Fakultesi Recruiting Kocaeli 41380 Turkey Details
Amerikan HAstanesi Onkoloji Birimi Teşvikiye Active, not recruiting Nişantaşı 34365 Turkey Details
Beatson West of Scotland Cancer Centre Recruiting Glasgow G12 0YN United Kingdom Details
Kings College Hospital Recruiting London SW9 8RR United Kingdom Details
Nottingham City Hospital; Dept of Haematology Recruiting Nottingham NG5 1PB United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field