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| NCT ID | NCT04211337 |
| Title | A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer (LIBRETTO-531) |
| Acronym | LIBRETTO-531 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Eli Lilly and Company |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior | child |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | United States | Details | |
| Mayo Clinic in Arizona - Phoenix | Phoenix | Arizona | 85054 | United States | Details | |
| City of Hope National Medical Center | Duarte | California | 91010-0269 | United States | Details | |
| University of California San Diego | La Jolla | California | 92037 | United States | Details | |
| UCLA Hematology/Oncology - Westwood (Building 100) | Los Angeles | California | 90095 | United States | Details | |
| University of California Davis (UC Davis) Comprehensive Cancer Center | Sacramento | California | 95817 | United States | Details | |
| UCSF Medical Center at Mission Bay | San Francisco | California | 94158 | United States | Details | |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Torrance | California | 90502 | United States | Details | |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| University of Michigan | Ann Arbor | Michigan | 48109 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Mayo Clinic in Rochester, Minnesota | Rochester | Minnesota | 55905 | United States | Details | |
| Washington University | Saint Louis | Missouri | 63110 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10017 | United States | Details | |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | United States | Details | |
| The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | United States | Details | |
| Providence Cancer Center Oncology Hematology Care | Portland | Oregon | 97213 | United States | Details | |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19114 | United States | Details | |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232-1305 | United States | Details | |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Wisconsin Hospitals and Clinics | Madison | Wisconsin | 53792 | United States | Details | |
| Chris O'Brien Lifehouse | Camperdown | New South Wales | 2050 | Australia | Details | |
| Royal North Shore Hospital | St Leonards | New South Wales | 2065 | Australia | Details | |
| The Alfred Hospital | Melbourne | Victoria | 3004 | Australia | Details | |
| Peter MacCallum Cancer Centre | Melbourne | Victoria | 3050 | Australia | Details | |
| Sir Charles Gairdner Hospital | Perth | Western Australia | 6009 | Australia | Details | |
| Antwerp University Hospital | Edegem | Antwerpen | 2650 | Belgium | Details | |
| Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman | Liège | 4000 | Belgium | Details | ||
| Oncocentro | Belo Horizonte | Minas Gerais | 30380-680 | Brazil | Details | |
| Hospital de Cancer de Londrina | Londrina | Paraná | 86015-520 | Brazil | Details | |
| Hospital de Clinicas de Porto Alegre | Porto Alegre | Rio Grande Do Sul | 90035-903 | Brazil | Details | |
| Fundação Pio XII - Hospital de Câncer de Barretos | Barretos | São Paulo | 14784400 | Brazil | Details | |
| Centro de Pesquisa Sao Lucas | Campinas | São Paulo | 13060-904 | Brazil | Details | |
| Hospital de Clínicas de Ribeirão Preto | Ribeirão Preto | São Paulo | 14051-140 | Brazil | Details | |
| Hospital Sírio Libanês | Sao Paulo | São Paulo | 01308-060 | Brazil | Details | |
| Instituto D'Or de Pesquisa e Ensino (IDOR) | Sao Paulo | São Paulo | 04543-000 | Brazil | Details | |
| Instituto Nacional de Câncer - INCA | Rio de Janeiro | 20230-130 | Brazil | Details | ||
| Grupo Oncoclínicas Botafogo | Rio de Janeiro | 22250-905 | Brazil | Details | ||
| Grupo COI - Clínicas Oncológicas Integradas | Rio de Janeiro | 22775-001 | Brazil | Details | ||
| Icesp - Instituto Do Câncer Do Estado de São Paulo | São Paulo | 01246-000 | Brazil | Details | ||
| Centro Paulista de Oncologia Clínica | São Paulo | 01452-000 | Brazil | Details | ||
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Anhui Provincial Hospital | Hefei | Anhui | 230071 | China | Details | |
| Beijing Tongren Hospital affiliated to Capital Medical University | Beijing | Beijing | 100730 | China | Details | |
| Chongqing University Cancer Hospital | Chongqing | Chongqing | 400030 | China | Details | |
| The First Affiliated Hospital Of Fujian Medical University | Fuzhou | Fujian | 350005 | China | Details | |
| Gansu Cancer Hospital | Lanzhou | Gansu | 730050 | China | Details | |
| Sun Yat-Sen University Cancer Centre | Guangzhou | Guangdong | 510060 | China | Details | |
| Harbin Medical University Cancer Hospital | Harbin | Heilongjiang | 150081 | China | Details | |
| Henan Cancer Hospital | Zhengzhou | Henan | 450008 | China | Details | |
| Hunan Cancer Hospital | Changsha | Hunan | 410013 | China | Details | |
| Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School | Nanjing | Jiangsu | 210000 | China | Details | |
| Jilin Cancer Hospital | Changchun | Jilin | 132000 | China | Details | |
| Jinan Central Hospital | Jinan | Shandong | 250013 | China | Details | |
| Fudan University Shanghai Cancer Center | Shanghai | Shanghai | 200032 | China | Details | |
| West China Hospital, Sichuan University | Cheng Du | Sichuan | 610041 | China | Details | |
| Tianjin Medical University Cancer Institute and Hospital | Tianjin | Tianjin | 300060 | China | Details | |
| First Affiliated Hospital of Kunming Medical University | Kunming | Yunnan | 650032 | China | Details | |
| Zhejiang Provincial People's Hospital | Hangzhou | Zhejiang | 310014 | China | Details | |
| Sir Run Run Shaw Hospital | Hangzhou | Zhejiang | 310016 | China | Details | |
| Zhejiang Cancer Hospital | Hangzhou | Zhejiang | 310022 | China | Details | |
| Fakultní nemocnice Brno Bohunice | Brno | Brno-město | 625 00 | Czechia | Details | |
| Fakultni nemocnice Motol | Praha | Praha 5 | 150 06 | Czechia | Details | |
| Fakultni nemocnice Olomouc | Olomouc | 779 00 | Czechia | Details | ||
| Centre Paul Strauss | Strasbourg | Alsace | 67065 | France | Details | |
| Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest | Bordeaux | Aquitaine | 33076 | France | Details | |
| Assistance Publique Hôpitaux de Marseille - Hôpital Nord | Marseille | Bouches-du-Rhône | 13915 | France | Details | |
| Centre François Baclesse | Caen | Calvados | 14076 | France | Details | |
| Centre Georges François Leclerc | Dijon | Côte-d'Or | 21079 | France | Details | |
| Institut Claudius Regaud | Toulouse | Haute-Garonne | 31059 | France | Details | |
| Centre Hospitalier Universitaire d'Angers | Angers | Maine-et-Loire | 49933 | France | Details | |
| Hopital Claude Huriez - CHU de Lille | Lille | Nord | 59037 | France | Details | |
| Pitie Salpetriere University Hospital | Paris | Orne | 75013 | France | Details | |
| Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne | Clermont-Ferrand | Puy-de-Dôme | 63011 | France | Details | |
| Centre Leon Berard | Lyon | Rhône-Alpes | 69008 | France | Details | |
| Gustave Roussy | Villejuif | Val-de-Marne | 94800 | France | Details | |
| Klinikum der Universität München Großhadern | München | Bayern | 81337 | Germany | Details | |
| Klinikum der Universität München Großhadern | Würzburg | Bayern | 97080 | Germany | Details | |
| Medizinische Hochschule Hannover | Hannover | Niedersachsen | 30625 | Germany | Details | |
| Universitaetsklinikum Essen | Essen | Nordrhein-Westfalen | 45122 | Germany | Details | |
| Universitätsmedizin Johannes Gutenberg Universität Mainz | Mainz | Rheinland-Pfalz | 55131 | Germany | Details | |
| Otto-von-Guericke-Universität Magdeburg | Magdeburg | Sachsen-Anhalt | 39120 | Germany | Details | |
| Charité Universitaetsmedizin Berlin - Campus Mitte | Berlin | 10117 | Germany | Details | ||
| Hämato-Onkologie Hamburg, Prof. Laack und Partner | Hamburg | 20251 | Germany | Details | ||
| Alexandra General Hospital of Athens | Athina | Attikí | 115 28 | Greece | Details | |
| University General Hospital of Heraklion | Heraklion | Irakleío | 711 10 | Greece | Details | |
| European Interbalkan Medical Center | Thessaloníki | Thessaloniki | 570 01 | Greece | Details | |
| Regional Cancer Centre - Thiruvananthapuram | Thiruvananthapuram | Kerala | 695011 | India | Details | |
| HCG Manavata Cancer Centre | Nashik | Maharashtra | 422001 | India | Details | |
| Grant Medical Foundation - Ruby Hall Clinic | Pune | Maharashtra | 411001 | India | Details | |
| Deenanath Mangeshkar Hospital & Research Centre | Pune | Maharashtra | 411004 | India | Details | |
| Apollo Gleneagles Hospitals Kolkata | Kolkata | West Bengal | 700054 | India | Details | |
| Post Graduate Institute of Medical Education & Research (PGIMER) | Chandigarh | 160012 | India | Details | ||
| Rabin Medical Center | Petah-Tikva | HaMerkaz | 4941492 | Israel | Details | |
| Sheba Medical Center | Ramat Gan | HaMerkaz | 5265601 | Israel | Details | |
| Hadassah Medical Center | Jerusalem | Yerushalayim | 9112001 | Israel | Details | |
| University of Naples Federico II | Napoli | Campania | 80131 | Italy | Details | |
| Policlinico Umberto I | Roma | Lazio | 00161 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milan | Lombardia | 20133 | Italy | Details | |
| Istituto Auxologico Italiano | Milan | Milano | 20122 | Italy | Details | |
| Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino | Torino | Piemonte | 10126 | Italy | Details | |
| Istituto Nazionale Tumori Regina Elena | Rome | Roma | 00144 | Italy | Details | |
| Azienda Ospedaliera Universitaria Pisana | Pisa | Toscana | 56124 | Italy | Details | |
| Ospedale Le Scotte | Siena | Toscana | 53100 | Italy | Details | |
| Istituto Oncologico Veneto IRCCS | Padova | Veneto | 35128 | Italy | Details | |
| Azienda Ospedaliera Garibaldi | Catania | 95124 | Italy | Details | ||
| Aichi Cancer Center Hospital | Nagoya | Aichi | 464-8681 | Japan | Details | |
| National Cancer Center Hospital East | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| Hokkaido University Hospital | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| Kobe University Hospital | Kobe | Hyogo | 650-0017 | Japan | Details | |
| Yokohama City University Hospital | Yokohama | Kanagawa | 236-0004 | Japan | Details | |
| Osaka University Hospital | Suita | Osaka | 565-0871 | Japan | Details | |
| Japanese Foundation for Cancer Research | Koto | Tokyo | 135-8550 | Japan | Details | |
| National Hospital Organization Kyushu Medical Center | Fukuoka | 810-8563 | Japan | Details | ||
| Chungbuk National University Hospital | Chungbuk | Chungcheongbuk-do [Chungbuk] | 28644 | Korea, Republic of | Details | |
| Asan Medical Center | Seoul | Korea | 05505 | Korea, Republic of | Details | |
| National Cancer Center | Goyang-si | Kyǒnggi-do | 10408 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | Seongnam | Kyǒnggi-do | 13620 | Korea, Republic of | Details | |
| Seoul National University Hospital | Seoul | Seoul-teukbyeolsi [Seoul] | 3080 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | Seoul | Seoul-teukbyeolsi [Seoul] | 3722 | Korea, Republic of | Details | |
| Samsung Medical Center | Seoul | Seoul-teukbyeolsi [Seoul] | 6351 | Korea, Republic of | Details | |
| Maastricht UMC+ | Maastricht | Limburg | 6229 HX | Netherlands | Details | |
| Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL) | Amsterdam | Noord-Holland | 1066 CX | Netherlands | Details | |
| Leids Universitair Medisch Centrum | Leiden | Zuid-Holland | 2333 ZA | Netherlands | Details | |
| University Medical Center Groningen | Groningen | 9713 GR | Netherlands | Details | ||
| Narodowy Instytut Onkologii - Oddzial w Gliwicach | Gliwice | Śląskie | 44-101 | Poland | Details | |
| Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej | Kielce | Świętokrzyskie | 25-734 | Poland | Details | |
| Clinic Evimed | Chelyabinsk | Chelyabinskaya Oblast' | 454048 | Russian Federation | Details | |
| A. Tsyb Medical Radiological Research Center - branch of the National Medical Research Radiological | Obninsk | Kalužskaja Oblast' | 249036 | Russian Federation | Details | |
| Fed State Budgetary Inst "N.N. Blokhin Med Center of Oncology" MHRF | Moscow | Moskva | 115478 | Russian Federation | Details | |
| Endocrinology Research Center of Rosmedtechnologies | Moscow | Moskva | 117292 | Russian Federation | Details | |
| Saint Petersburg State University | Saint Petersburg | Sankt-Peterburg | 190020 | Russian Federation | Details | |
| Saint-Petersburg City Clinical Oncology Dispensary | Saint Petersburg | Sankt-Peterburg | 198255 | Russian Federation | Details | |
| Hospital Universitari Vall d'Hebron | Barcelona | Barcelona [Barcelona] | 8035 | Spain | Details | |
| Instituto Catalan de Oncologia - Hospital Duran i Reynals | L'Hospitalet de Llobregat | Catalunya [Cataluña] | 8907 | Spain | Details | |
| Institut Català d'Oncologia (ICO) - Girona | Girona | Girona [Gerona] | 17007 | Spain | Details | |
| Clinica Universidad de Navarra | Madrid | Madrid, Comunidad De | 28027 | Spain | Details | |
| Hospital Universitario Ramón y Cajal | Madrid | Madrid, Comunidad De | 28034 | Spain | Details | |
| Hospital Universitario 12 de Octubre | Madrid | Madrid, Comunidad De | 28041 | Spain | Details | |
| Hospital Universitario La Paz | Madrid | Madrid, Comunidad De | 28046 | Spain | Details | |
| Hospital Universitario Virgen de la Victoria | Malaga | Málaga | 29010 | Spain | Details | |
| Clinica Universidad de Navarra | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital General Universitario Gregorio Marañon | Madrid | 28009 | Spain | Details | ||
| Hospital Clinico San Carlos | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| National Cheng-Kung Uni. Hosp. | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
| Velindre Cancer Centre | Cardiff | Cardiff [Caerdydd Gb-crd] | CF14 2TL | United Kingdom | Details | |
| Weston Park Hospital | Sheffield | England | S10 2SJ | United Kingdom | Details | |
| Gartnavel General Hospital | Glasgow | Glasgow City | g12OYN | United Kingdom | Details | |
| Royal Marsden Hospital (Chelsea) | London | Kensington And Chelsea | SW3 6JJ | United Kingdom | Details | |
| University College London Hospital | London | London, City Of | NW1 2PG | United Kingdom | Details | |
| Royal Marsden NHS Trust | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| Royal Marsden Hospital (Sutton) | London | Sutton | SM2 5PT | United Kingdom | Details |