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| NCT ID | NCT04216290 |
| Title | A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, the INSPIRE Study |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Anchorage Associates in Radiation Medicine | Anchorage | Alaska | 98508 | United States | Details | |
| Alaska Breast Care and Surgery LLC | Anchorage | Alaska | 99508 | United States | Details | |
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | United States | Details | |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | United States | Details | |
| Anchorage Oncology Centre | Anchorage | Alaska | 99508 | United States | Details | |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | United States | Details | |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | United States | Details | |
| Mercy Hospital Fort Smith | Fort Smith | Arkansas | 72903 | United States | Details | |
| CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas | 71913 | United States | Details | |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | United States | Details | |
| VA Palo Alto Health Care System | Palo Alto | California | 94304 | United States | Details | |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | United States | Details | |
| Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | 80907 | United States | Details | |
| Porter Adventist Hospital | Denver | Colorado | 80210 | United States | Details | |
| Saint Anthony Hospital | Lakewood | Colorado | 80228 | United States | Details | |
| Littleton Adventist Hospital | Littleton | Colorado | 80122 | United States | Details | |
| Longmont United Hospital | Longmont | Colorado | 80501 | United States | Details | |
| Parker Adventist Hospital | Parker | Colorado | 80138 | United States | Details | |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | United States | Details | |
| Beebe South Coastal Health Campus | Frankford | Delaware | 19945 | United States | Details | |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | United States | Details | |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | United States | Details | |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | United States | Details | |
| Sibley Memorial Hospital | Washington | District of Columbia | 20016 | United States | Details | |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | United States | Details | |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | United States | Details | |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | United States | Details | |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | United States | Details | |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | United States | Details | |
| Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | 83605 | United States | Details | |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | United States | Details | |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | United States | Details | |
| Idaho Urologic Institute-Meridian | Meridian | Idaho | 83642 | United States | Details | |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | United States | Details | |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83686 | United States | Details | |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | United States | Details | |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | United States | Details | |
| Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | 83301 | United States | Details | |
| Rush - Copley Medical Center | Aurora | Illinois | 60504 | United States | Details | |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | United States | Details | |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | United States | Details | |
| Memorial Hospital of Carbondale | Carbondale | Illinois | 62902 | United States | Details | |
| SIH Cancer Institute | Carterville | Illinois | 62918 | United States | Details | |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | United States | Details | |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60611 | United States | Details | |
| Carle at The Riverfront | Danville | Illinois | 61832 | United States | Details | |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | United States | Details | |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | United States | Details | |
| Northwestern Medicine Cancer Center Kishwaukee | DeKalb | Illinois | 60115 | United States | Details | |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | United States | Details | |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | United States | Details | |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | United States | Details | |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | United States | Details | |
| Western Illinois Cancer Treatment Center | Galesburg | Illinois | 61401 | United States | Details | |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | United States | Details | |
| Edward Hines Jr VA Hospital | Hines | Illinois | 60141 | United States | Details | |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | United States | Details | |
| Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois | 60045 | United States | Details | |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | United States | Details | |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | United States | Details | |
| Loyola University Medical Center | Maywood | Illinois | 60153 | United States | Details | |
| Good Samaritan Regional Health Center | Mount Vernon | Illinois | 62864 | United States | Details | |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | United States | Details | |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | United States | Details | |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | United States | Details | |
| OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center | Pekin | Illinois | 61554 | United States | Details | |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | United States | Details | |
| OSF Saint Francis Radiation Oncology at Peoria Cancer Center | Peoria | Illinois | 61615 | United States | Details | |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | United States | Details | |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | United States | Details | |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | United States | Details | |
| Valley Radiation Oncology | Peru | Illinois | 61354 | United States | Details | |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | United States | Details | |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | United States | Details | |
| Springfield Clinic | Springfield | Illinois | 62702 | United States | Details | |
| Memorial Medical Center | Springfield | Illinois | 62781 | United States | Details | |
| Carle Cancer Center | Urbana | Illinois | 61801 | United States | Details | |
| The Carle Foundation Hospital | Urbana | Illinois | 61801 | United States | Details | |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | United States | Details | |
| Mary Greeley Medical Center | Ames | Iowa | 50010 | United States | Details | |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | United States | Details | |
| Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | 50325 | United States | Details | |
| Mercy Cancer Center-West Lakes | Clive | Iowa | 50325 | United States | Details | |
| Greater Regional Medical Center | Creston | Iowa | 50801 | United States | Details | |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | United States | Details | |
| Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | 50309 | United States | Details | |
| Broadlawns Medical Center | Des Moines | Iowa | 50314 | United States | Details | |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | United States | Details | |
| Mission Cancer and Blood - Laurel | Des Moines | Iowa | 50314 | United States | Details | |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | United States | Details | |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | United States | Details | |
| Methodist West Hospital | West Des Moines | Iowa | 50266-7700 | United States | Details | |
| Mercy Medical Center-West Lakes | West Des Moines | Iowa | 50266 | United States | Details | |
| Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | 40504 | United States | Details | |
| Saint Joseph Hospital East | Lexington | Kentucky | 40509 | United States | Details | |
| Jewish Hospital | Louisville | Kentucky | 40202 | United States | Details | |
| Baptist Health Louisville | Louisville | Kentucky | 40207 | United States | Details | |
| UofL Health Medical Center Northeast | Louisville | Kentucky | 40245 | United States | Details | |
| East Jefferson General Hospital | Metairie | Louisiana | 70006 | United States | Details | |
| LSU Healthcare Network / Metairie Multi-Specialty Clinic | Metairie | Louisiana | 70006 | United States | Details | |
| Louisiana State University Health Science Center | New Orleans | Louisiana | 70112 | United States | Details | |
| University Medical Center New Orleans | New Orleans | Louisiana | 70112 | United States | Details | |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | United States | Details | |
| Lafayette Family Cancer Center-EMMC | Brewer | Maine | 04412 | United States | Details | |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | United States | Details | |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | United States | Details | |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | United States | Details | |
| Saint Joseph Mercy Brighton | Brighton | Michigan | 48114 | United States | Details | |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | United States | Details | |
| Saint Joseph Mercy Canton | Canton | Michigan | 48188 | United States | Details | |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | United States | Details | |
| Saint Joseph Mercy Chelsea | Chelsea | Michigan | 48118 | United States | Details | |
| Ascension Saint John Hospital | Detroit | Michigan | 48236 | United States | Details | |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | United States | Details | |
| Hurley Medical Center | Flint | Michigan | 48503 | United States | Details | |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | United States | Details | |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | United States | Details | |
| 21st Century Oncology-Pontiac | Pontiac | Michigan | 48341 | United States | Details | |
| Saint Joseph Mercy Oakland | Pontiac | Michigan | 48341 | United States | Details | |
| Ascension Saint Mary's Hospital | Saginaw | Michigan | 48601 | United States | Details | |
| Saint John Macomb-Oakland Hospital | Warren | Michigan | 48093 | United States | Details | |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | United States | Details | |
| Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | 56401 | United States | Details | |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | United States | Details | |
| Essentia Health - Deer River Clinic | Deer River | Minnesota | 56636 | United States | Details | |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | United States | Details | |
| Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | 55805 | United States | Details | |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | United States | Details | |
| Unity Hospital | Fridley | Minnesota | 55432 | United States | Details | |
| Essentia Health Hibbing Clinic | Hibbing | Minnesota | 55746 | United States | Details | |
| Essentia Health Sandstone | Sandstone | Minnesota | 55072 | United States | Details | |
| Essentia Health Virginia Clinic | Virginia | Minnesota | 55792 | United States | Details | |
| Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri | 63011 | United States | Details | |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | United States | Details | |
| Southeast Cancer Center | Cape Girardeau | Missouri | 63703 | United States | Details | |
| Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | 63141 | United States | Details | |
| Parkland Health Center - Farmington | Farmington | Missouri | 63640 | United States | Details | |
| Capital Region Southwest Campus | Jefferson City | Missouri | 65109 | United States | Details | |
| Mercy Hospital Joplin | Joplin | Missouri | 64804 | United States | Details | |
| Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | 65401 | United States | Details | |
| Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | 65401 | United States | Details | |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Mercy Hospital South | Saint Louis | Missouri | 63128 | United States | Details | |
| Siteman Cancer Center-South County | Saint Louis | Missouri | 63129 | United States | Details | |
| Missouri Baptist Medical Center | Saint Louis | Missouri | 63131 | United States | Details | |
| Siteman Cancer Center at Christian Hospital | Saint Louis | Missouri | 63136 | United States | Details | |
| Mercy Hospital Saint Louis | Saint Louis | Missouri | 63141 | United States | Details | |
| Siteman Cancer Center at Saint Peters Hospital | Saint Peters | Missouri | 63376 | United States | Details | |
| Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | 63670 | United States | Details | |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | United States | Details | |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | United States | Details | |
| Missouri Baptist Sullivan Hospital | Sullivan | Missouri | 63080 | United States | Details | |
| BJC Outpatient Center at Sunset Hills | Sunset Hills | Missouri | 63127 | United States | Details | |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | United States | Details | |
| Bozeman Deaconess Hospital | Bozeman | Montana | 59715 | United States | Details | |
| Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | 59405 | United States | Details | |
| Great Falls Clinic | Great Falls | Montana | 59405 | United States | Details | |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | United States | Details | |
| Community Medical Hospital | Missoula | Montana | 59804 | United States | Details | |
| CHI Health Saint Francis | Grand Island | Nebraska | 68803 | United States | Details | |
| CHI Health Good Samaritan | Kearney | Nebraska | 68847 | United States | Details | |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | United States | Details | |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | United States | Details | |
| Alegent Health Lakeside Hospital | Omaha | Nebraska | 68130 | United States | Details | |
| Creighton University Medical Center | Omaha | Nebraska | 68131 | United States | Details | |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87102 | United States | Details | |
| Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | 45220 | United States | Details | |
| Bethesda North Hospital | Cincinnati | Ohio | 45242 | United States | Details | |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | United States | Details | |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | 73120 | United States | Details | |
| Saint Charles Health System | Bend | Oregon | 97701 | United States | Details | |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | United States | Details | |
| Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | 97015 | United States | Details | |
| Bay Area Hospital | Coos Bay | Oregon | 97420 | United States | Details | |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | United States | Details | |
| Providence Portland Medical Center | Portland | Oregon | 97213 | United States | Details | |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | United States | Details | |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | United States | Details | |
| Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | 18017 | United States | Details | |
| Christiana Care Health System-Concord Health Center | Chadds Ford | Pennsylvania | 19317 | United States | Details | |
| Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | United States | Details | |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | United States | Details | |
| Gibbs Cancer Center-Gaffney | Gaffney | South Carolina | 29341 | United States | Details | |
| Gibbs Cancer Center-Pelham | Greer | South Carolina | 29651 | United States | Details | |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | United States | Details | |
| MGC Hematology Oncology-Union | Union | South Carolina | 29379 | United States | Details | |
| University of Tennessee - Knoxville | Knoxville | Tennessee | 37920 | United States | Details | |
| Saint Joseph Regional Cancer Center | Bryan | Texas | 77802 | United States | Details | |
| Sovah Health Martinsville | Martinsville | Virginia | 24115 | United States | Details | |
| Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | 98520 | United States | Details | |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | United States | Details | |
| Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton | Washington | 98310 | United States | Details | |
| Harrison Medical Center | Bremerton | Washington | 98310 | United States | Details | |
| Highline Medical Center-Main Campus | Burien | Washington | 98166 | United States | Details | |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | United States | Details | |
| Swedish Cancer Institute-Edmonds | Edmonds | Washington | 98026 | United States | Details | |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | United States | Details | |
| Swedish Cancer Institute-Issaquah | Issaquah | Washington | 98029 | United States | Details | |
| Providence Regional Cancer System-Lacey | Lacey | Washington | 98503 | United States | Details | |
| PeaceHealth Saint John Medical Center | Longview | Washington | 98632 | United States | Details | |
| Swedish Medical Center-Ballard Campus | Seattle | Washington | 98107 | United States | Details | |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | United States | Details | |
| PeaceHealth United General Medical Center | Sedro-Woolley | Washington | 98284 | United States | Details | |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | United States | Details | |
| Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | 99362 | United States | Details | |
| Duluth Clinic Ashland | Ashland | Wisconsin | 54806 | United States | Details | |
| Northwest Wisconsin Cancer Center | Ashland | Wisconsin | 54806 | United States | Details | |
| Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | 54701 | United States | Details | |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | United States | Details | |
| Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | 54548 | United States | Details | |
| Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | 54868 | United States | Details | |
| Marshfield Medical Center-River Region at Stevens Point | Stevens Point | Wisconsin | 54482 | United States | Details | |
| Marshfield Medical Center - Weston | Weston | Wisconsin | 54476 | United States | Details | |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | United States | Details |