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NCT ID NCT04222972
Title A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Blueprint Medicines Corporation

lung non-small cell carcinoma


Carboplatin + Pembrolizumab + Pemetrexed Disodium

Carboplatin + Paclitaxel + Pembrolizumab

Carboplatin + Nab-paclitaxel + Pembrolizumab


Cisplatin + Gemcitabine

Carboplatin + Gemcitabine

Cisplatin + Pemetrexed Disodium

Cisplatin + Pembrolizumab + Pemetrexed Disodium

Carboplatin + Pemetrexed Disodium

Age Groups: senior | adult
Covered Countries USA | ITA | FRA | ESP | DEU | CAN | BEL

Facility Status City State Zip Country Details
UC Irvine Medical Center Completed Orange California 92868 United States Details
Southern California Kaiser Permanente Completed San Diego California 92108 United States Details
Sylvester Comprehensive Cancer Center; University of Miami School of Medicine Withdrawn Miami Florida 33136 United States Details
University of Maryland Marlene and Stewart Greenebaum Cancer Center Withdrawn Baltimore Maryland 21201 United States Details
University of Michigan Hospital Withdrawn Ann Arbor Michigan 48109 United States Details
UPMC - Hillman Cancer Center Withdrawn Pittsburgh Pennsylvania 15232 United States Details
Texas Oncology - Baylor Charles A. Sammons Cancer Center Withdrawn Dallas Texas 75246 United States Details
University of Texas Health Science Center Withdrawn Dallas Texas 75390 United States Details
Millennium Research & Clinical Development Recruiting Houston Texas 77090 United States Details
Royal North Shore Hospital; Department of Medical Oncology Recruiting St Leonards New South Wales 2065 Australia Details
Flinders Medical Centre Recruiting Bedford Park South Australia 5042 Australia Details
Institut Jules Bordet; Pulmonary Oncology Recruiting Anderlecht 1070 Belgium Details
UZ Antwerpen Active, not recruiting Edegem 2650 Belgium Details
Institut universitaire de cardiologie et de pneumologie de Québec (Hôpital Laval) Recruiting Ste. Foy Quebec G1V 4G5 Canada Details
Clinica CIMCA Recruiting San José 10103 Costa Rica Details
Rigshospitalet, Onkologisk Klinik; Klinisk Forskningsenhed Withdrawn København Ø 2100 Denmark Details
Helsinki University Central Hospital; Dept of Oncology Withdrawn Helsinki 00250 Finland Details
Institut Bergonie CLCC Bordeaux Recruiting Bordeaux 33000 France Details
Hôpital Ambroise Paré - Boulogne-Billancourt Recruiting Boulogne Billancourt 92100 France Details
Hôpital Louis Pradel, Hospices Civils de Lyon Recruiting Bron 69677 France Details
CHRU Lille Service de Pneumologie et Oncologie Thoracique Recruiting Lille 59000 France Details
Institut Paoli Calmettes; Oncologie Medicale Recruiting Marseille 13273 France Details
Hopital Bichat Claude Bernard; Oncologie Serv. Recruiting Paris 75018 France Details
Institut Curie; Oncologie Medicale Withdrawn Paris 75231 France Details
Hopital Tenon;Pneumologie Recruiting Paris 75970 France Details
Hopital de Pontchaillou; Service de Pneumologie Recruiting Rennes 35033 France Details
Ico Rene Gauducheau; Oncologie Recruiting Saint Herblain 44805 France Details
CHU Strasbourg - Nouvel Hopital Civil Recruiting Strasbourg 67091 France Details
CHU de Toulouse - Hôpital Larrey; Service de pneumologie et oncologie pneumologique Recruiting Toulouse cedex 9 31100 France Details
Institut Gustave Roussy; Departement Oncologie Medicale Recruiting Villejuif 94805 France Details
Universitätsklinikum Carl Gustav Carus, Medizinische Klinik I, Pneumologie MK1-A13 Active, not recruiting Dresden 01307 Germany Details
Klinikum Esslingen Recruiting Esslingen 73730 Germany Details
Asklepios-Fachkliniken Muenchen-Gauting; Onkologie Active, not recruiting Gauting 82131 Germany Details
Thoraxklinik Heidelberg gGmbH Active, not recruiting Heidelberg 69126 Germany Details
Klinikum der Universität München; Campus Großhadern; Med. Klinik und Poliklinik V Recruiting München 81377 Germany Details
Pius-Hospital; Klinik fuer Haematologie und Onkologie Recruiting Oldenburg 26121 Germany Details
Leopoldina-Krankenhaus Medizinische Klinik II Recruiting Schweinfurt 97422 Germany Details
Klinik Schillerhöhe; Pneumologische Onkologie Recruiting Stuttgart 70376 Germany Details
St. James Hospital; Oncology Recruiting Dublin 8 Ireland Details
Shaare Zedek Medical Center; Oncology Dept Withdrawn Jerusalem 9103102 Israel Details
Meir Medical Center; Oncology Withdrawn Kfar-Saba 4428164 Israel Details
Sourasky / Ichilov Hospital; Dept. of Oncology Withdrawn Tel Aviv 6423906 Israel Details
Ospedale Clinicizzato SS Annunziata Recruiting Chieti Abruzzo 66100 Italy Details
Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale Recruiting Napoli Campania 80131 Italy Details
Università degli Studi della Campania Luigi Vanvitelli Recruiting Napoli Campania 80131 Italy Details
Ospedale Provinciale Santa Maria Delle Croci; Oncologia Medica Recruiting Ravenna Emilia-Romagna 48100 Italy Details
Istituto Nazionale Tumori Regina Elena Recruiting Roma Lazio 00144 Italy Details
AZ. Ospedaliera San Giovanni - Addolorata Recruiting Roma Lazio 00184 Italy Details
Azienda Ospedaliera Sant'Andrea Recruiting Roma Lazio 00189 Italy Details
Irccs Ospedale San Raffaele Recruiting Milano Lombardia 20132 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori Active, not recruiting Milano Lombardia 20133 Italy Details
Istituto Europeo Di Oncologia Active, not recruiting Milano Lombardia 20141 Italy Details
A.O.U. Maggiore della Carità Recruiting Novara Piemonte 28100 Italy Details
IRCCS Giovanni Paolo II Istituto Oncologico Recruiting Bari Puglia 70124 Italy Details
Azienda Ospedaliera Universitaria Pisana - Ospedale Cisanello; Dipartimento Cardio Toraco Vascolare Recruiting Pisa Toscana 56124 Italy Details
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II Recruiting Padova Veneto 35128 Italy Details
A.O.U. INTEGRATA DI VERONA-Ospedale Civile Maggiore Borgo Trento; U.O.C. Oncologia Recruiting Verona Veneto 37126 Italy Details
Hirosaki University Hospital Recruiting Aomori 036-8563 Japan Details
Ehime University Hospital Recruiting Ehime 791-0295 Japan Details
Kyushu University Hospital Recruiting Fukuoka 812-8582 Japan Details
Kurume University Hospital Recruiting Fukuoka 830-0011 Japan Details
National Hospital Organization Hokkaido Cancer Center Recruiting Hokkaido 003-0804 Japan Details
National Hospital Organization Himeji Medical Center Active, not recruiting Hyogo 670-8520 Japan Details
Iwate Medical University Hospital Recruiting Iwate 028-3695 Japan Details
Kanagawa Cancer Center Recruiting Kanagawa 241-8515 Japan Details
Sendai Kousei Hospital Recruiting Miyagi 980-0873 Japan Details
Kurashiki Central Hospital Recruiting Okayama 710-8602 Japan Details
Osaka City General Hospital Recruiting Osaka 534-0021 Japan Details
Osaka International Cancer Institute Recruiting Osaka 541-8567 Japan Details
Kansai Medical University Hospital Active, not recruiting Osaka 573-1191 Japan Details
Saitama Cancer Center Recruiting Saitama 362-0806 Japan Details
Juntendo University Hospital Active, not recruiting Tokyo 113-8431 Japan Details
The Cancer Institute Hospital of JFCR Active, not recruiting Tokyo 135-8550 Japan Details
National Hospital Organization Yamaguchi - Ube Medical Center Recruiting Yamaguchi 755-0241 Japan Details
Seoul National University Hospital Recruiting Seoul 03080 Korea, Republic of Details
Severance Hospital, Yonsei University Health System Active, not recruiting Seoul 03722 Korea, Republic of Details
Asan Medical Center Recruiting Seoul 05505 Korea, Republic of Details
COI Centro Oncologico Internacional SAPI de CV Recruiting Tijuana BAJA California SUR 22010 Mexico Details
Health Pharma Professional Research Recruiting Cdmx Mexico CITY (federal District) 03100 Mexico Details
Oncologico Potosino Recruiting San Luis Potosí SAN LUIS Potosi 78209 Mexico Details
NKI/AvL Active, not recruiting Amsterdam 1066 CX Netherlands Details
Universitair Medisch Centrum Groningen Recruiting Groningen 9713 GZ Netherlands Details
Maastricht University Medical Center Recruiting Maastricht 6229 HX Netherlands Details
Oslo universitetssykehus HF, Ullevål, Kreftsenteret Recruiting Oslo 0450 Norway Details
Hemato Oncología de Panamá Especializada Recruiting Panama City 0801 Panama Details
Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad; Klinika Nowot.Pluca i Klatki Piers Recruiting Warszawa 02-781 Poland Details
Hospital Garcia de Orta; Servico de Pneumologia Recruiting Almada 2801-951 Portugal Details
Hospital de Braga; Serviço de Pneumologia Recruiting Braga 4710-243 Portugal Details
IPO do Porto; Servico de Oncologia Medica Recruiting Porto 4200-072 Portugal Details
Centro Hospitalar de Vila Nova de Gaia / Espinho E.P.E Recruiting Vila Nova de Gaia 4434-502 Portugal Details
Hospital Univ. Central de Asturias; Servicio de Oncologia Recruiting Oviedo Asturias 33011 Spain Details
Hospital Universitario Germans Trias i Pujol Recruiting Badalona Barcelona 08916 Spain Details
Hospital Universitario Marques de Valdecilla; Servicio de Oncologia Recruiting Santander Cantabria 39008 Spain Details
Complejo Hospitalario Universitario A Coruña Recruiting A Coruña LA Coruña 15006 Spain Details
Hospital Universitario Puerta de Hierro; Servicio de Oncologia Recruiting Majadahonda Madrid 28222 Spain Details
Hospital Universitari Vall d'Hebron Recruiting Barcelona 08035 Spain Details
Hospital Clínic. Barcelona Recruiting Barcelona 08036 Spain Details
Hospital General Universitario Gregorio Marañon; Servicio de Oncologia Recruiting Madrid 28007 Spain Details
Hospital Ramon y Cajal; Servicio de Oncologia Recruiting Madrid 28034 Spain Details
Hospital Universitario 12 de Octubre Recruiting Madrid 28041 Spain Details
Hospital Regional Universitario de Malaga Recruiting Malaga 29010 Spain Details
Hospital Universitario Virgen del Rocio; Servicio de Oncologia Recruiting Sevilla 41013 Spain Details
Hospital General Universitario de Valencia; Servicio de oncologia Recruiting Valencia 46014 Spain Details
Hosp Clinico Univ Lozano Blesa; División De Oncología Médica Recruiting Zaragoza 50009 Spain Details
Karolinska Universitetssjukhuset, Solna; Kliniska prövningsenheten Z:4:01 Active, not recruiting Stockholm 171 76 Sweden Details
UniversitätsSpital Zürich; Zentrum für Hämatologie und Onkologie, Klinik für Onkologie Recruiting Zürich 8091 Switzerland Details
Adana City Hospital, Medical Oncology Recruiting Adana 01060 Turkey Details
Adana Baskent University Hospital; Medical Oncology Recruiting Adana 01120 Turkey Details
Ankara City Hospital Recruiting Ankara 06490 Turkey Details
Medipol Mega Üniversite Hastanesi Göztepe Recruiting Istanbul 34214 Turkey Details
İzmir Medical Park; Onkoloji Recruiting Izmır 35575 Turkey Details
Velindre Cancer Centre; Oncology Dept Recruiting Cardiff CF14 2TL United Kingdom Details
Leicester Royal Infirmary; Dept. of Medical Oncology Recruiting Leicester LE1 5WW United Kingdom Details
University College Hospital; Department of Oncology Recruiting London N7 9NH United Kingdom Details
Guys & St Thomas Hospital; Department of Oncology Recruiting London SE1 9RT United Kingdom Details
Royal Marsden Hospital; Dept of Med-Onc Recruiting London SW3 6JJ United Kingdom Details
Christie Hospital Nhs Trust; Medical Oncology Recruiting Manchester M2O 4BX United Kingdom Details
Royal Marsden Hospital; Dept of Medical Oncology Recruiting Sutton SM2 5PT United Kingdom Details
*Shaded cells indicate that there was no data available from for the field