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| NCT ID | NCT04222972 |
| Title | A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) (AcceleRET-Lung) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Blueprint Medicines Corporation |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UC Irvine Medical Center | Completed | Orange | California | 92868 | United States | Details |
| Southern California Kaiser Permanente | Completed | San Diego | California | 92108 | United States | Details |
| Sylvester Comprehensive Cancer Center; University of Miami School of Medicine | Withdrawn | Miami | Florida | 33136 | United States | Details |
| University of Maryland Marlene and Stewart Greenebaum Cancer Center | Withdrawn | Baltimore | Maryland | 21201 | United States | Details |
| University of Michigan Hospital | Withdrawn | Ann Arbor | Michigan | 48109 | United States | Details |
| UPMC - Hillman Cancer Center | Withdrawn | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Withdrawn | Dallas | Texas | 75246 | United States | Details |
| University of Texas Health Science Center | Withdrawn | Dallas | Texas | 75390 | United States | Details |
| Millennium Research & Clinical Development | Recruiting | Houston | Texas | 77090 | United States | Details |
| Fundación CENIT para la Investigación en Neurociencias | Recruiting | Buenos Aires | C1125ABD | Argentina | Details | |
| Hospital Britanico; Oncologia | Recruiting | Buenos Aires | C1280AEB | Argentina | Details | |
| Centro Oncologico Korben; Oncology | Recruiting | Ciudad Autonoma Buenos Aires | C1426AGE | Argentina | Details | |
| Centro Oncologico Riojano Integral (CORI) | Recruiting | La Rioja | F5300COE | Argentina | Details | |
| Royal North Shore Hospital; Department of Medical Oncology | Recruiting | St Leonards | New South Wales | 2065 | Australia | Details |
| Flinders Medical Centre | Recruiting | Bedford Park | South Australia | 5042 | Australia | Details |
| Mogilev Regional Oncology Center | Withdrawn | Mogilev | Mahilyowskaya Voblasts' | 212018 | Belarus | Details |
| State Inst N.N. Alexandrov Republican Scientific & Practical Centre of Oncology & Medical Radiology | Withdrawn | A/g Lesnoy, Minsk Region | Minsk | 223040 | Belarus | Details |
| Vitebsk Regional Clinical Oncology Dispensary | Withdrawn | Vitebsk | Vitsyebskaya Voblasts' | BU-210603 | Belarus | Details |
| Institut Jules Bordet; Pulmonary Oncology | Recruiting | Anderlecht | 1070 | Belgium | Details | |
| UZ Antwerpen | Active, not recruiting | Edegem | 2650 | Belgium | Details | |
| Liga Norte Riograndense Contra O Câncer | Recruiting | Natal | RN | 59040150 | Brazil | Details |
| Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda | Recruiting | Ijui | RS | 98700-000 | Brazil | Details |
| Hospital Sao Lucas - PUCRS | Recruiting | Porto Alegre | RS | 90610-000 | Brazil | Details |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | Recruiting | Sao Paulo | SP | 01246-000 | Brazil | Details |
| Hospital A. C. Camargo; Oncologia | Recruiting | Sao Paulo | SP | 01509-010 | Brazil | Details |
| Institut universitaire de cardiologie et de pneumologie de Québec (Hôpital Laval) | Withdrawn | Ste. Foy | Quebec | G1V 4G5 | Canada | Details |
| Clinica CIMCA | Recruiting | San José | 10103 | Costa Rica | Details | |
| Rigshospitalet, Onkologisk Klinik; Klinisk Forskningsenhed | Withdrawn | København Ø | 2100 | Denmark | Details | |
| Helsinki University Central Hospital; Dept of Oncology | Withdrawn | Helsinki | 00250 | Finland | Details | |
| Institut Bergonie CLCC Bordeaux | Recruiting | Bordeaux | 33000 | France | Details | |
| Hôpital Ambroise Paré - Boulogne-Billancourt | Recruiting | Boulogne Billancourt | 92100 | France | Details | |
| Hôpital Louis Pradel, Hospices Civils de Lyon | Recruiting | Bron | 69677 | France | Details | |
| CHRU Lille Service de Pneumologie et Oncologie Thoracique | Recruiting | Lille | 59000 | France | Details | |
| Institut Paoli Calmettes; Oncologie Medicale | Recruiting | Marseille | 13273 | France | Details | |
| Hopital Bichat Claude Bernard; Oncologie Serv. | Recruiting | Paris | 75018 | France | Details | |
| Institut Curie; Oncologie Medicale | Withdrawn | Paris | 75231 | France | Details | |
| Hopital Tenon;Pneumologie | Recruiting | Paris | 75970 | France | Details | |
| Hopital de Pontchaillou; Service de Pneumologie | Recruiting | Rennes | 35033 | France | Details | |
| Ico Rene Gauducheau; Oncologie | Recruiting | Saint Herblain | 44805 | France | Details | |
| CHU Strasbourg - Nouvel Hopital Civil | Recruiting | Strasbourg | 67091 | France | Details | |
| CHU de Toulouse - Hôpital Larrey; Service de pneumologie et oncologie pneumologique | Recruiting | Toulouse cedex 9 | 31100 | France | Details | |
| Institut Gustave Roussy; Departement Oncologie Medicale | Recruiting | Villejuif | 94805 | France | Details | |
| Universitätsklinikum Carl Gustav Carus, Medizinische Klinik I, Pneumologie MK1-A13 | Active, not recruiting | Dresden | 01307 | Germany | Details | |
| Klinikum Esslingen | Withdrawn | Esslingen | 73730 | Germany | Details | |
| Asklepios-Fachkliniken Muenchen-Gauting; Onkologie | Active, not recruiting | Gauting | 82131 | Germany | Details | |
| Thoraxklinik Heidelberg gGmbH | Withdrawn | Heidelberg | 69126 | Germany | Details | |
| Klinikum der Universität München; Campus Großhadern; Med. Klinik und Poliklinik V | Recruiting | München | 81377 | Germany | Details | |
| Pius-Hospital; Klinik fuer Haematologie und Onkologie | Completed | Oldenburg | 26121 | Germany | Details | |
| Leopoldina-Krankenhaus Medizinische Klinik II | Recruiting | Schweinfurt | 97422 | Germany | Details | |
| Klinik Schillerhöhe; Pneumologische Onkologie | Recruiting | Stuttgart | 70376 | Germany | Details | |
| St. James Hospital; Oncology | Recruiting | Dublin | 8 | Ireland | Details | |
| Shaare Zedek Medical Center; Oncology Dept | Withdrawn | Jerusalem | 9103102 | Israel | Details | |
| Meir Medical Center; Oncology | Withdrawn | Kfar-Saba | 4428164 | Israel | Details | |
| Sourasky / Ichilov Hospital; Dept. of Oncology | Withdrawn | Tel Aviv | 6423906 | Israel | Details | |
| Ospedale Clinicizzato SS Annunziata | Active, not recruiting | Chieti | Abruzzo | 66100 | Italy | Details |
| Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale | Recruiting | Napoli | Campania | 80131 | Italy | Details |
| Università degli Studi della Campania Luigi Vanvitelli | Recruiting | Napoli | Campania | 80131 | Italy | Details |
| Ospedale Provinciale Santa Maria Delle Croci; Oncologia Medica | Active, not recruiting | Ravenna | Emilia-Romagna | 48100 | Italy | Details |
| Istituto Nazionale Tumori Regina Elena | Recruiting | Roma | Lazio | 00144 | Italy | Details |
| AZ. Ospedaliera San Giovanni - Addolorata | Recruiting | Roma | Lazio | 00184 | Italy | Details |
| Azienda Ospedaliera Sant'Andrea | Recruiting | Roma | Lazio | 00189 | Italy | Details |
| Irccs Ospedale San Raffaele | Recruiting | Milano | Lombardia | 20132 | Italy | Details |
| Fondazione IRCCS Istituto Nazionale dei Tumori | Active, not recruiting | Milano | Lombardia | 20133 | Italy | Details |
| Istituto Europeo Di Oncologia | Active, not recruiting | Milano | Lombardia | 20141 | Italy | Details |
| A.O.U. Maggiore della Carità | Recruiting | Novara | Piemonte | 28100 | Italy | Details |
| IRCCS Giovanni Paolo II Istituto Oncologico | Active, not recruiting | Bari | Puglia | 70124 | Italy | Details |
| Azienda Ospedaliera Universitaria Pisana - Ospedale Cisanello; Dipartimento Cardio Toraco Vascolare | Recruiting | Pisa | Toscana | 56124 | Italy | Details |
| IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II | Recruiting | Padova | Veneto | 35128 | Italy | Details |
| A.O.U. INTEGRATA DI VERONA-Ospedale Civile Maggiore Borgo Trento; U.O.C. Oncologia | Recruiting | Verona | Veneto | 37126 | Italy | Details |
| Nagoya University Hospital | Recruiting | Aichi | 466-8560 | Japan | Details | |
| Hirosaki University Hospital | Recruiting | Aomori | 036-8563 | Japan | Details | |
| National Cancer Center Hospital East | Recruiting | Chiba | 277-8577 | Japan | Details | |
| Ehime University Hospital | Recruiting | Ehime | 791-0295 | Japan | Details | |
| Kyushu University Hospital | Recruiting | Fukuoka | 812-8582 | Japan | Details | |
| Kurume University Hospital | Recruiting | Fukuoka | 830-0011 | Japan | Details | |
| National Hospital Organization Hokkaido Cancer Center | Recruiting | Hokkaido | 003-0804 | Japan | Details | |
| National Hospital Organization Himeji Medical Center | Active, not recruiting | Hyogo | 670-8520 | Japan | Details | |
| Iwate Medical University Hospital | Recruiting | Iwate | 028-3695 | Japan | Details | |
| Kanagawa Cancer Center | Recruiting | Kanagawa | 241-8515 | Japan | Details | |
| Sendai Kousei Hospital | Recruiting | Miyagi | 980-0873 | Japan | Details | |
| Niigata Cancer Center Hospital | Recruiting | Niigata | 951-8566 | Japan | Details | |
| Kurashiki Central Hospital | Recruiting | Okayama | 710-8602 | Japan | Details | |
| Osaka City General Hospital | Recruiting | Osaka | 534-0021 | Japan | Details | |
| Osaka International Cancer Institute | Recruiting | Osaka | 541-8567 | Japan | Details | |
| Kansai Medical University Hospital | Active, not recruiting | Osaka | 573-1191 | Japan | Details | |
| Saitama Cancer Center | Recruiting | Saitama | 362-0806 | Japan | Details | |
| Juntendo University Hospital | Active, not recruiting | Tokyo | 113-8431 | Japan | Details | |
| The Cancer Institute Hospital of JFCR | Active, not recruiting | Tokyo | 135-8550 | Japan | Details | |
| National Hospital Organization Yamaguchi - Ube Medical Center | Active, not recruiting | Yamaguchi | 755-0241 | Japan | Details | |
| National Cancer Center | Recruiting | Goyang-si | 10408 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | Active, not recruiting | Seoul | 003-722 | Korea, Republic of | Details | |
| Seoul National University Hospital | Recruiting | Seoul | 03080 | Korea, Republic of | Details | |
| Asan Medical Center | Active, not recruiting | Seoul | 05505 | Korea, Republic of | Details | |
| COI Centro Oncologico Internacional SAPI de CV | Withdrawn | Tijuana | BAJA California SUR | 22010 | Mexico | Details |
| Health Pharma Professional Research | Active, not recruiting | Cdmx | Mexico CITY (federal District) | 03100 | Mexico | Details |
| Oncologico Potosino | Recruiting | San Luis Potosí | SAN LUIS Potosi | 78209 | Mexico | Details |
| NKI/AvL | Active, not recruiting | Amsterdam | 1066 CX | Netherlands | Details | |
| Universitair Medisch Centrum Groningen | Recruiting | Groningen | 9713 GZ | Netherlands | Details | |
| Maastricht University Medical Center | Recruiting | Maastricht | 6229 HX | Netherlands | Details | |
| Auckland City Hospital, Cancer and Blood Research | Recruiting | Auckland | 1023 | New Zealand | Details | |
| Oslo universitetssykehus HF, Ullevål, Kreftsenteret | Recruiting | Oslo | 0450 | Norway | Details | |
| Hemato Oncología de Panamá Especializada | Recruiting | Panama City | 0801 | Panama | Details | |
| Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad; Klinika Nowot.Pluca i Klatki Piers | Recruiting | Warszawa | 02-781 | Poland | Details | |
| Hospital Garcia de Orta; Servico de Pneumologia | Recruiting | Almada | 2801-951 | Portugal | Details | |
| Hospital de Braga; Serviço de Pneumologia | Recruiting | Braga | 4710-243 | Portugal | Details | |
| IPO do Porto; Servico de Oncologia Medica | Recruiting | Porto | 4200-072 | Portugal | Details | |
| Centro Hospitalar de Vila Nova de Gaia / Espinho E.P.E | Recruiting | Vila Nova de Gaia | 4434-502 | Portugal | Details | |
| Hospital Univ. Central de Asturias; Servicio de Oncologia | Recruiting | Oviedo | Asturias | 33011 | Spain | Details |
| Hospital Universitario Germans Trias i Pujol | Recruiting | Badalona | Barcelona | 08916 | Spain | Details |
| Insititut Catala D'Oncologia | Recruiting | Hospitalet de Llobregat | Barcelona | 08908 | Spain | Details |
| Hospital Universitario Marques de Valdecilla; Servicio de Oncologia | Active, not recruiting | Santander | Cantabria | 39008 | Spain | Details |
| Complejo Hospitalario Universitario A Coruña | Recruiting | A Coruña | LA Coruña | 15006 | Spain | Details |
| Hospital Universitario Puerta de Hierro; Servicio de Oncologia | Recruiting | Majadahonda | Madrid | 28222 | Spain | Details |
| Hospital Universitari Vall d'Hebron | Recruiting | Barcelona | 08035 | Spain | Details | |
| Hospital Clínic. Barcelona | Recruiting | Barcelona | 08036 | Spain | Details | |
| Hospital General Universitario Gregorio Marañon; Servicio de Oncologia | Recruiting | Madrid | 28007 | Spain | Details | |
| Hospital Ramon y Cajal; Servicio de Oncologia | Active, not recruiting | Madrid | 28034 | Spain | Details | |
| Hospital Universitario 12 de Octubre | Recruiting | Madrid | 28041 | Spain | Details | |
| HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia | Recruiting | Madrid | 28050 | Spain | Details | |
| Hospital Regional Universitario de Malaga | Recruiting | Malaga | 29010 | Spain | Details | |
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Recruiting | Sevilla | 41013 | Spain | Details | |
| Hospital General Universitario de Valencia; Servicio de oncologia | Recruiting | Valencia | 46014 | Spain | Details | |
| Hosp Clinico Univ Lozano Blesa; División De Oncología Médica | Recruiting | Zaragoza | 50009 | Spain | Details | |
| Karolinska Universitetssjukhuset, Solna; Kliniska prövningsenheten Z:4:01 | Recruiting | Stockholm | 171 76 | Sweden | Details | |
| UniversitätsSpital Zürich; Zentrum für Hämatologie und Onkologie, Klinik für Onkologie | Recruiting | Zürich | 8091 | Switzerland | Details | |
| Adana City Hospital, Medical Oncology | Recruiting | Adana | 01060 | Turkey | Details | |
| Adana Baskent University Hospital; Medical Oncology | Recruiting | Adana | 01120 | Turkey | Details | |
| Ankara Bilkent City Hospital | Recruiting | Ankara | 06490 | Turkey | Details | |
| Medipol Mega Üniversite Hastanesi Göztepe | Recruiting | Istanbul | 34214 | Turkey | Details | |
| ?zmir Medical Point; Oncology | Recruiting | Kar?iyaka | 35575 | Turkey | Details | |
| CI of Kherson Regional Council Kherson Regional Oncology Dispensary | Withdrawn | Kherson | Kherson Governorate | 73000 | Ukraine | Details |
| Ivano-Frankivsk Regional Oncology Center | Withdrawn | Ivano-Frankivsk | 76018 | Ukraine | Details | |
| MI Zaporizhzhia Regional Clinical Oncological Dispensary Zaporizhzhia SMU Ch of Oncology | Withdrawn | Zaporizhzhya | 69040 | Ukraine | Details | |
| Velindre Cancer Centre; Oncology Dept | Recruiting | Cardiff | CF14 2TL | United Kingdom | Details | |
| Leicester Royal Infirmary; Dept. of Medical Oncology | Recruiting | Leicester | LE1 5WW | United Kingdom | Details | |
| University College Hospital; Department of Oncology | Recruiting | London | N7 9NH | United Kingdom | Details | |
| Guys & St Thomas Hospital; Department of Oncology | Recruiting | London | SE1 9RT | United Kingdom | Details | |
| Royal Marsden Hospital; Dept of Med-Onc | Recruiting | London | SW3 6JJ | United Kingdom | Details | |
| Christie Hospital Nhs Trust; Medical Oncology | Recruiting | Manchester | M2O 4BX | United Kingdom | Details | |
| Royal Marsden Hospital; Dept of Medical Oncology | Recruiting | Sutton | SM2 5PT | United Kingdom | Details |