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| NCT ID | NCT04223856 |
| Title | Enfortumab Vedotin and Pembrolizumab, With or Without Chemotherapy, vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer (EV-302) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Astellas Pharma Global Development, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | DEU | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Ironwood Cancer & Research Centers - Chandler | Completed | Chandler | Arizona | 85224 | United States | Details |
| Arizona Oncology Associates PD - HOPE | Completed | Tucson | Arizona | 85710 | United States | Details |
| Providence St Joseph Medical Center | Completed | Burbank | California | 91505 | United States | Details |
| City of Hope National Medical Center | Active, not recruiting | Duarte | California | 91010 | United States | Details |
| University of California Los Angeles Medical Center | Active, not recruiting | Los Angeles | California | 90095 | United States | Details |
| University of California Irvine - Newport | Active, not recruiting | Orange | California | 92868 | United States | Details |
| Rocky Mountain Cancer Centers - Aurora | Active, not recruiting | Aurora | Colorado | 80012 | United States | Details |
| University of Colorado Hospital / University of Colorado | Active, not recruiting | Aurora | Colorado | 80045 | United States | Details |
| Cancer Centers of Colorado - Denver | Active, not recruiting | Denver | Colorado | 80218 | United States | Details |
| Yale Cancer Center | Active, not recruiting | New Haven | Connecticut | 06520 | United States | Details |
| Eastern CT Hematology and Oncology Associates | Active, not recruiting | Norwich | Connecticut | 06360 | United States | Details |
| Lombardi Cancer Center / Georgetown University Medical Center | Active, not recruiting | Washington | District of Columbia | 20007 | United States | Details |
| H. Lee Moffitt Cancer Center and Research Institute | Completed | Tampa | Florida | 33612 | United States | Details |
| Winship Cancer Institute / Emory University School of Medicine | Completed | Atlanta | Georgia | 30322 | United States | Details |
| Georgia Cancer Specialists / Northside Hospital Cancer Institute | Completed | Marietta | Georgia | 30060 | United States | Details |
| Louisiana State University/ East Jefferson General Hospital | Completed | Metairie | Louisiana | 70006 | United States | Details |
| Maine Health Cancer Care | Active, not recruiting | Biddeford | Maine | 04046 | United States | Details |
| Johns Hopkins Medical Center | Active, not recruiting | Baltimore | Maryland | 21231 | United States | Details |
| Comprehensive Cancer Centers of Nevada | Active, not recruiting | Las Vegas | Nevada | 89169 | United States | Details |
| New Mexico Cancer Center | Active, not recruiting | Albuquerque | New Mexico | 87109 | United States | Details |
| New York University (NYU) Cancer Institute | Active, not recruiting | New York | New York | 10016 | United States | Details |
| Mount Sinai Medical Center | Active, not recruiting | New York | New York | 10029 | United States | Details |
| Memorial Sloan Kettering Cancer Center | Active, not recruiting | New York | New York | 10065 | United States | Details |
| Vidant Medical Center | Active, not recruiting | Greenville | North Carolina | 27834 | United States | Details |
| The Cleveland Clinic | Active, not recruiting | Cleveland | Ohio | 44195 | United States | Details |
| Toledo Clinic Cancer Center | Completed | Toledo | Ohio | 43623 | United States | Details |
| Hillman Cancer Center / University of Pittsburgh Medical Center | Completed | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| Saint Francis Hospital / Bon Secours - South Carolina | Completed | Greenville | South Carolina | 29607 | United States | Details |
| West Cancer Center & Research Institute | Completed | Germantown | Tennessee | 38138 | United States | Details |
| University of Texas Southwestern Medical Center | Active, not recruiting | Dallas | Texas | 75390 | United States | Details |
| UT Health East Texas Hope Cancer Center | Active, not recruiting | Tyler | Texas | 75701 | United States | Details |
| Huntsman Cancer Institute | Active, not recruiting | Salt Lake City | Utah | 84112 | United States | Details |
| University of Virginia | Active, not recruiting | Charlottesville | Virginia | 22908 | United States | Details |
| Seattle Cancer Care Alliance / University of Washington | Active, not recruiting | Seattle | Washington | 98109 | United States | Details |
| Site AR54008 | Active, not recruiting | Buenos Aire | C1019ABS | Argentina | Details | |
| Site AR54011 | Active, not recruiting | Caba | C1426ANZ | Argentina | Details | |
| Site AR54005 | Active, not recruiting | Cordoba | X5004FHP | Argentina | Details | |
| Site AR54006 | Active, not recruiting | La Rioja | 5300 | Argentina | Details | |
| Site AR54004 | Active, not recruiting | Mendoza | M5500AYB | Argentina | Details | |
| Site AR54001 | Active, not recruiting | Rosario | 2000 | Argentina | Details | |
| Site AR54002 | Active, not recruiting | San Miguel | T400GTB | Argentina | Details | |
| Site AR54012 | Active, not recruiting | Tucuman | T4000IAK | Argentina | Details | |
| Site AR54003 | Active, not recruiting | Viedma | 8500 | Argentina | Details | |
| Site AU61003 | Active, not recruiting | Box Hill | 3128 | Australia | Details | |
| Site AUS61001 | Active, not recruiting | Douglas | 4814 | Australia | Details | |
| Site AUS61004 | Active, not recruiting | Heidelberg | 3084 | Australia | Details | |
| Site AUS61002 | Active, not recruiting | Macquarie Park | 2109 | Australia | Details | |
| Site AUS61006 | Active, not recruiting | South Australia | 5112 | Australia | Details | |
| Site AU61005 | Active, not recruiting | South Brisbane | 4101 | Australia | Details | |
| Site BE32003 | Active, not recruiting | Brussels | 1200 | Belgium | Details | |
| Site BE32002 | Active, not recruiting | Ghent | 9000 | Belgium | Details | |
| Site BE32001 | Active, not recruiting | Liege | 4000 | Belgium | Details | |
| Site BE32007 | Active, not recruiting | Lueven | 3000 | Belgium | Details | |
| Site BE32006 | Active, not recruiting | Roeselare | 8800 | Belgium | Details | |
| Site CA11004 | Active, not recruiting | Calgary | Alberta | T2N 4N2 | Canada | Details |
| Site CA11003 | Active, not recruiting | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| Site CA11006 | Active, not recruiting | Vancouver | British Columbia | V5Z 4E6 | Canada | Details |
| Site CA11002 | Active, not recruiting | Hamilton | Ontario | L8V 1C3 | Canada | Details |
| Site CA11009 | Active, not recruiting | London | Ontario | N6A 5A5 | Canada | Details |
| Site CA11011 | Active, not recruiting | Oshawa | Ontario | L1G 2B9 | Canada | Details |
| Site CA11012 | Active, not recruiting | Toronto | Ontario | M4N 3M5 | Canada | Details |
| Site CA11005 | Active, not recruiting | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Site CA11010 | Active, not recruiting | Montreal | Quebec | H2X 0A9 | Canada | Details |
| Site CA11001 | Active, not recruiting | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Site CA11008 | Active, not recruiting | Quebec | G1R 2J6 | Canada | Details | |
| Site CN86009 | Recruiting | Beijing City | 100021 | China | Details | |
| Site CN86001 | Recruiting | Beijing | 100036 | China | Details | |
| Site CN86004 | Recruiting | Beijing | 100050 | China | Details | |
| Site CN86005 | Recruiting | Beijing | 100191 | China | Details | |
| Site CN86015 | Recruiting | Bengbu | 233000 | China | Details | |
| Site CN86003 | Recruiting | Changchun | 130021 | China | Details | |
| Site CN86016 | Recruiting | Changsha | 410013 | China | Details | |
| Site CN86007 | Recruiting | Chongqing | 400038 | China | Details | |
| Site CN86020 | Recruiting | Gunagzhou | 510280 | China | Details | |
| Site CN86018 | Recruiting | Hangzhou | 0571 | China | Details | |
| Site CN86013 | Recruiting | Hangzhou | 310014 | China | Details | |
| Site CN86017 | Recruiting | Nanjing | 210008 | China | Details | |
| Site CN86014 | Recruiting | Shanghai | 200040 | China | Details | |
| Site CN86011 | Recruiting | Shenyang City | 110022 | China | Details | |
| Site CN86019 | Recruiting | Tianjin | 453000 | China | Details | |
| Site CN86008 | Recruiting | Wuhan City | 430030 | China | Details | |
| Site CZ42006 | Active, not recruiting | Brno | 656 91 | Czechia | Details | |
| Site CZ42001 | Active, not recruiting | Hradec Kralove | 500 05 | Czechia | Details | |
| Site CZ42004 | Active, not recruiting | Olomouc | 779 00 | Czechia | Details | |
| Site CZ42005 | Active, not recruiting | Praha 4-Krc | 140 59 | Czechia | Details | |
| Site DK45001 | Active, not recruiting | Aalborg | 9100 | Denmark | Details | |
| Site DK45003 | Active, not recruiting | Aarhus N | 8200 | Denmark | Details | |
| Site FR33014 | Active, not recruiting | Bordeaux | 33000 | France | Details | |
| Site FR33016 | Active, not recruiting | Lyon | 69373 | France | Details | |
| Site FR33003 | Active, not recruiting | Nice Cedex 2 | 06189 | France | Details | |
| Site FR33020 | Active, not recruiting | Pierre-Bénite | 69495 | France | Details | |
| Site FR33013 | Active, not recruiting | Strasbourg | 67200 | France | Details | |
| Site FR33017 | Active, not recruiting | TOURS Cedex 09 | 37044 | France | Details | |
| Site FR33011 | Active, not recruiting | Villejuif-Cedex-France | 94805 | France | Details | |
| Site DE49003 | Active, not recruiting | Berlin | 10117 | Germany | Details | |
| Site DE49013 | Active, not recruiting | Bielefeld | 33611 | Germany | Details | |
| Site DE49016 | Active, not recruiting | Düsseldorf | 40225 | Germany | Details | |
| Site DE49014 | Completed | Erlangen | 91054 | Germany | Details | |
| Site DE49011 | Active, not recruiting | Essen | 45147 | Germany | Details | |
| Site DE49007 | Active, not recruiting | Frankfurt am Main | 60488 | Germany | Details | |
| Site DE49015 | Active, not recruiting | Gottingen | 37099 | Germany | Details | |
| Site DE49005 | Active, not recruiting | Heidelberg | 69120 | Germany | Details | |
| Site DE49009 | Active, not recruiting | Herne | 44649 | Germany | Details | |
| Site DE49006 | Active, not recruiting | Jena | 07747 | Germany | Details | |
| Site DE49001 | Active, not recruiting | Lubeck | 23538 | Germany | Details | |
| Site DE49008 | Active, not recruiting | Magdeburg | 39120 | Germany | Details | |
| Site DE49012 | Active, not recruiting | Mannheim | 68167 | Germany | Details | |
| Site DE49002 | Active, not recruiting | Munchen | 81675 | Germany | Details | |
| Site DE49004 | Active, not recruiting | Tübingen | 72076 | Germany | Details | |
| Site DE49010 | Active, not recruiting | Ulm | 89081 | Germany | Details | |
| Site HU36003 | Active, not recruiting | Budapest | 1083 | Hungary | Details | |
| Site HU36002 | Active, not recruiting | Budapest | 1122 | Hungary | Details | |
| Site HU36006 | Active, not recruiting | Debrecen | 4032 | Hungary | Details | |
| Site HU36001 | Completed | Nyiregyhaza | 4400 | Hungary | Details | |
| Site HU36005 | Active, not recruiting | Szolnok | 5004 | Hungary | Details | |
| Site IL97203 | Active, not recruiting | Beer Sheva | 84101 | Israel | Details | |
| Site IL97201 | Active, not recruiting | Haifa | 31096 | Israel | Details | |
| Site IL97209 | Active, not recruiting | Holon | 58100 | Israel | Details | |
| Site IL97206 | Active, not recruiting | Jerusalem | 91120 | Israel | Details | |
| Site IL97202 | Active, not recruiting | Kfar Saba | 44281 | Israel | Details | |
| Site IL97208 | Active, not recruiting | Petach Tikva | 49414 | Israel | Details | |
| Site IL97211 | Active, not recruiting | Rehovot | 76100 | Israel | Details | |
| Site IL97210 | Active, not recruiting | Tel Aviv | 64239 | Israel | Details | |
| Site IL97204 | Active, not recruiting | Tel Hashomer | 52621 | Israel | Details | |
| Site IL97205 | Active, not recruiting | Zerifin | 70300 | Israel | Details | |
| Site IT39005 | Active, not recruiting | Areezo | 52100 | Italy | Details | |
| Site IT39008 | Active, not recruiting | Candiolo | 10060 | Italy | Details | |
| Site IT39009 | Active, not recruiting | Cremona | 26100 | Italy | Details | |
| Site IT39006 | Active, not recruiting | Genova | 16132 | Italy | Details | |
| Site IT39003 | Active, not recruiting | Meldola | 47014 | Italy | Details | |
| Site IT39014 | Active, not recruiting | Milano | 20132 | Italy | Details | |
| Site IT39007 | Active, not recruiting | Milano | 20141 | Italy | Details | |
| Site IT39004 | Active, not recruiting | Pisa | 56126 | Italy | Details | |
| Site IT39002 | Active, not recruiting | Terni | 05100 | Italy | Details | |
| Site IT39011 | Active, not recruiting | Torrette | 60126 | Italy | Details | |
| Site IT39001 | Active, not recruiting | Verona | 37134 | Italy | Details | |
| Site JP81002 | Active, not recruiting | Bunkyo City | Japan | Details | ||
| Site JP81009 | Active, not recruiting | Chiba | Japan | Details | ||
| Site JP81018 | Active, not recruiting | Chiba | Japan | Details | ||
| Site JP81013 | Active, not recruiting | Fukuoka | Japan | Details | ||
| Site JP81020 | Active, not recruiting | Fukuoka | Japan | Details | ||
| Site JP81011 | Active, not recruiting | Hirosaki | Japan | Details | ||
| Site JP81006 | Active, not recruiting | Kawasaki-shi | Japan | Details | ||
| Site JP81001 | Active, not recruiting | Koto-ku | Japan | Details | ||
| Site JP81017 | Active, not recruiting | Kyoto | Japan | Details | ||
| Site JP81015 | Active, not recruiting | Niigata | Japan | Details | ||
| Site JP81005 | Active, not recruiting | Okayama | Japan | Details | ||
| Site JP81016 | Active, not recruiting | Osakasayama-Shi | Japan | Details | ||
| Site JP81008 | Active, not recruiting | Osaka | Japan | Details | ||
| Site JP81007 | Active, not recruiting | Sapporo | Japan | Details | ||
| Site JP81012 | Active, not recruiting | Sendai-city | Japan | Details | ||
| Site JP81014 | Active, not recruiting | Tokushima | Japan | Details | ||
| Site JP81019 | Active, not recruiting | Tokyo | Japan | Details | ||
| Site JP81003 | Completed | Toyama | Japan | Details | ||
| Site JP81004 | Active, not recruiting | Tsukuba | Japan | Details | ||
| Site JP81010 | Active, not recruiting | Ube | Japan | Details | ||
| Site KR82001 | Active, not recruiting | Daejeon | 301-721 | Korea, Republic of | Details | |
| Site KR82002 | Active, not recruiting | Goyang-si | 10408 | Korea, Republic of | Details | |
| Site KR82008 | Active, not recruiting | Hwasun | 519-763 | Korea, Republic of | Details | |
| Site KR82004 | Active, not recruiting | Seongnam-si | 13605 | Korea, Republic of | Details | |
| Site KR82003 | Active, not recruiting | Seoul | 03722 | Korea, Republic of | Details | |
| Site KR82005 | Active, not recruiting | Seoul | 05505 | Korea, Republic of | Details | |
| Site KR82007 | Active, not recruiting | Seoul | 135-710 | Korea, Republic of | Details | |
| Site KR82006 | Active, not recruiting | Seoul | 137-701 | Korea, Republic of | Details | |
| Site NL31005 | Active, not recruiting | Amsterdam, Noord-Holland | 1066 CX | Netherlands | Details | |
| Site NL31002 | Active, not recruiting | Amsterdam | 1066 CX | Netherlands | Details | |
| Site NL31001 | Active, not recruiting | Amsterdam | 1081 HV | Netherlands | Details | |
| Site NL31007 | Active, not recruiting | Leeuwarden | 8934 AD | Netherlands | Details | |
| Site NL31004 | Active, not recruiting | Nieuwegein | 3435 CM | Netherlands | Details | |
| Site NL31003 | Active, not recruiting | Rotterdam | 3075 EA | Netherlands | Details | |
| Site NL31006 | Active, not recruiting | Utrecht | 3584 CX | Netherlands | Details | |
| Site PL48002 | Active, not recruiting | Warszawa | 01-748 | Poland | Details | |
| Site RU70016 | Active, not recruiting | Arkhangelsk | 163045 | Russian Federation | Details | |
| Site RU70013 | Active, not recruiting | Barnaul | 656049 | Russian Federation | Details | |
| Site RU70020 | Active, not recruiting | Ivanovo | 153040 | Russian Federation | Details | |
| Site RU70014 | Terminated | Krasnoyarsk | 660133 | Russian Federation | Details | |
| Site RU70006 | Active, not recruiting | Leningradskaya Oblast' | 188663 | Russian Federation | Details | |
| Site RU70004 | Terminated | Moscow | 105077 | Russian Federation | Details | |
| Site RU70011 | Active, not recruiting | Moscow | 123056 | Russian Federation | Details | |
| Site RU70003 | Active, not recruiting | Moscow | 125284 | Russian Federation | Details | |
| Site RU70017 | Active, not recruiting | Nizhniy Novgorod | 603074 | Russian Federation | Details | |
| Site RU70002 | Active, not recruiting | Omsk | 644013 | Russian Federation | Details | |
| Site RU70019 | Terminated | Pyatigorsk | 357502 | Russian Federation | Details | |
| Site RU70010 | Active, not recruiting | Saint Petersburg | 195271 | Russian Federation | Details | |
| Site RU70007 | Active, not recruiting | Saint Petersburg | 197082 | Russian Federation | Details | |
| Site RU70012 | Active, not recruiting | Saint-Petersburg | 197758 | Russian Federation | Details | |
| Site RU70009 | Active, not recruiting | Saransk | 430032 | Russian Federation | Details | |
| Site RU70008 | Terminated | St. Petersburg | 197758 | Russian Federation | Details | |
| Site RU70015 | Active, not recruiting | Tyumen | 625041 | Russian Federation | Details | |
| Site RU70005 | Terminated | Ufa | 450000 | Russian Federation | Details | |
| Site SG65001 | Active, not recruiting | Singapore | 119074 | Singapore | Details | |
| Site SG65002 | Active, not recruiting | Singapore | 169610 | Singapore | Details | |
| Site SG65003 | Active, not recruiting | Singapore | 308433 | Singapore | Details | |
| Site ES34017 | Active, not recruiting | Barcelona | 08003 | Spain | Details | |
| Site ES34010 | Active, not recruiting | Barcelona | 08035 | Spain | Details | |
| Site ES34006 | Active, not recruiting | Barcelona | 08036 | Spain | Details | |
| Site ES34001 | Active, not recruiting | Barcelona | 08041 | Spain | Details | |
| Site ES34008 | Active, not recruiting | Barcelona | 08907 | Spain | Details | |
| Site ES34013 | Active, not recruiting | Cordoba | 14004 | Spain | Details | |
| Site ES34021 | Active, not recruiting | Lugo | 27003 | Spain | Details | |
| Site ES34018 | Active, not recruiting | Madrid | 28007 | Spain | Details | |
| Site ES34002 | Active, not recruiting | Madrid | 28034 | Spain | Details | |
| Site ES34003 | Active, not recruiting | Madrid | 28040 | Spain | Details | |
| Site ES34015 | Active, not recruiting | Madrid | 28041 | Spain | Details | |
| Site ES34004 | Active, not recruiting | Manresa | 08243 | Spain | Details | |
| Site ES34020 | Active, not recruiting | Pamplona | 31008 | Spain | Details | |
| Site ES34016 | Active, not recruiting | Sabadell | 08208 | Spain | Details | |
| Site ES34012 | Active, not recruiting | Santander | 39008 | Spain | Details | |
| Site ES34007 | Active, not recruiting | Sevilla | 41013 | Spain | Details | |
| Site ES34019 | Active, not recruiting | Valencia | 46009 | Spain | Details | |
| Site ES34009 | Active, not recruiting | Valencia | 46014 | Spain | Details | |
| Site CH41004 | Active, not recruiting | Basel | 4031 | Switzerland | Details | |
| Site CH41002 | Active, not recruiting | Bern | 3010 | Switzerland | Details | |
| Site CH41001 | Active, not recruiting | Chur | 7000 | Switzerland | Details | |
| Site CH41003 | Active, not recruiting | Winterthur | 8401 | Switzerland | Details | |
| Site TW88603 | Active, not recruiting | Kaohsiung | 83301 | Taiwan | Details | |
| Site TW88602 | Active, not recruiting | Kweishan | 333 | Taiwan | Details | |
| Site TW88607 | Active, not recruiting | Taichung | 40447 | Taiwan | Details | |
| Site TW88606 | Active, not recruiting | Taichung | 40705 | Taiwan | Details | |
| Site TW88604 | Active, not recruiting | Tainan | 70403 | Taiwan | Details | |
| Site TW88605 | Active, not recruiting | Taipei | 10002 | Taiwan | Details | |
| Site TW88601 | Active, not recruiting | Taipei | 11217 | Taiwan | Details | |
| Site TH66004 | Active, not recruiting | Bangkok | 10330 | Thailand | Details | |
| Site TH66003 | Active, not recruiting | Bangkok | 10400 | Thailand | Details | |
| Site TH66005 | Active, not recruiting | Chiang Mai | 50200 | Thailand | Details | |
| Site TH66002 | Active, not recruiting | HatYai | 90110 | Thailand | Details | |
| Site TH66006 | Active, not recruiting | Krung Thep Maha Nakhon | 10700 | Thailand | Details | |
| Site TH66007 | Active, not recruiting | Muang | 40002 | Thailand | Details | |
| Site TH66001 | Active, not recruiting | Ratchathewi | 10400 | Thailand | Details | |
| Site TR90007 | Active, not recruiting | Ankara | 6100 | Turkey | Details | |
| Site TR90009 | Active, not recruiting | Ankara | 6230 | Turkey | Details | |
| Site TR90005 | Active, not recruiting | Antalya | 07059 | Turkey | Details | |
| Site TR90004 | Active, not recruiting | Edirne | 22030 | Turkey | Details | |
| Site TR90008 | Active, not recruiting | Istanbul | 34093 | Turkey | Details | |
| Site TR90003 | Active, not recruiting | Istanbul | 34214 | Turkey | Details | |
| Site TR90002 | Active, not recruiting | Istanbul | 81450 | Turkey | Details | |
| Site TR90001 | Active, not recruiting | Konya | 42080 | Turkey | Details | |
| Site TR90006 | Active, not recruiting | Malatya | 44280 | Turkey | Details | |
| Site UK44005 | Active, not recruiting | Glasgow | G12 0YN | United Kingdom | Details | |
| Site UK44001 | Active, not recruiting | London | EC1M 6BQ | United Kingdom | Details | |
| Site UK44009 | Active, not recruiting | London | W6 8RF | United Kingdom | Details | |
| Site UK44006 | Active, not recruiting | Oxford | OX3 7LE | United Kingdom | Details | |
| Site UK44010 | Active, not recruiting | Plymouth | PL6 8DH | United Kingdom | Details | |
| Site UK44002 | Active, not recruiting | Preston | PR2 9HT | United Kingdom | Details | |
| Site UK44003 | Active, not recruiting | Sheffield | S10 2RX | United Kingdom | Details | |
| Site UK44008 | Active, not recruiting | Southampton | SO16 6YD | United Kingdom | Details |