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| NCT ID | NCT04241185 |
| Title | Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Washington Cancer Institute at MedStar Washington Hospital Center ( Site 0041) | RECRUITING | Washington | District of Columbia | 20010 | United States | Details |
| Bay Pines VA Medical Center ( Site 0055) | ACTIVE_NOT_RECRUITING | Bay Pines | Florida | 33744 | United States | Details |
| AdventHealth Orlando-AdventHealth Medical Group Hematology & Oncology at Orlando ( Site 0004) | COMPLETED | Orlando | Florida | 32804 | United States | Details |
| Norton Cancer Institute ( Site 0044) | COMPLETED | Louisville | Kentucky | 40207 | United States | Details |
| Pikeville Medical Center ( Site 0009) | COMPLETED | Pikeville | Kentucky | 41501 | United States | Details |
| Baltimore VA Medical Center ( Site 0054) | COMPLETED | Baltimore | Maryland | 21201 | United States | Details |
| Washington University ( Site 0003) | RECRUITING | Saint Louis | Missouri | 63110 | United States | Details |
| Summit Medical Group Cancer Center ( Site 6008) | RECRUITING | Florham Park | New Jersey | 07932 | United States | Details |
| John Theurer Cancer Center at Hackensack University Medical Center ( Site 0005) | RECRUITING | Hackensack | New Jersey | 07601 | United States | Details |
| New York Oncology Hematology P.C ( Site 0024) | RECRUITING | Albany | New York | 12206 | United States | Details |
| Roswell Park Cancer Institute ( Site 6009) | RECRUITING | Buffalo | New York | 14203 | United States | Details |
| Winthrop University Hospital ( Site 0069) | RECRUITING | Mineola | New York | 11501 | United States | Details |
| New York University Perlmutter Cancer Center ( Site 0001) | RECRUITING | New York | New York | 10016 | United States | Details |
| Cleveland Clinic ( Site 0062) | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| MidLantic urology ( Site 0070) | RECRUITING | Bala-Cynwyd | Pennsylvania | 19004 | United States | Details |
| Saint Francis Cancer Center ( Site 0026) | COMPLETED | Greenville | South Carolina | 29607 | United States | Details |
| Carolina Urologic Research Center ( Site 0002) | RECRUITING | Myrtle Beach | South Carolina | 29572 | United States | Details |
| Urology San Antonio Research ( Site 6010) | RECRUITING | San Antonio | Texas | 78229 | United States | Details |
| Inova Schar Cancer Institute ( Site 6006) | COMPLETED | Fairfax | Virginia | 22031 | United States | Details |
| West Virginia University - Charleston Area Medical Center ( Site 6003) | RECRUITING | Charleston | West Virginia | 25304 | United States | Details |
| Froedtert and Medical College of Wisconsin ( Site 0022) | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Liverpool Hospital ( Site 0220) | COMPLETED | Liverpool | New South Wales | 2170 | Australia | Details |
| GenesisCare North Shore ( Site 0217) | RECRUITING | St Leonards | New South Wales | 2065 | Australia | Details |
| Monash Medical Centre ( Site 0216) | COMPLETED | Clayton | Victoria | 3168 | Australia | Details |
| Austin Health ( Site 0218) | RECRUITING | Heidelberg | Victoria | 3084 | Australia | Details |
| Sir Charles Gairdner Hospital ( Site 0223) | COMPLETED | Nedlands | Western Australia | 6009 | Australia | Details |
| Oncocentro Valdivia ( Site 7055) | RECRUITING | Valdivia | Los Rios | 5112129 | Chile | Details |
| FALP ( Site 7056) | RECRUITING | Santiago | Region M. De Santiago | 7500921 | Chile | Details |
| Bradfordhill-Clinical Area ( Site 7051) | RECRUITING | Santiago | Region M. De Santiago | 8420383 | Chile | Details |
| ONCOCENTRO APYS-ACEREY ( Site 7054) | RECRUITING | Viña del Mar | Valparaiso | 2520598 | Chile | Details |
| Bradford Hill Norte ( Site 7052) | RECRUITING | Antofagasta | 1240000 | Chile | Details | |
| Fakultni nemocnice Olomouc ( Site 0559) | RECRUITING | Olomouc | 77900 | Czechia | Details | |
| 2. LF UK a FN Motol ( Site 0555) | RECRUITING | Praha 5 | 150 06 | Czechia | Details | |
| Nemocnice Na Bulovce ( Site 0556) | COMPLETED | Praha 8 | 180 81 | Czechia | Details | |
| Herlev og Gentofte Hospital. ( Site 0401) | COMPLETED | Herlev | Hovedstaden | 2730 | Denmark | Details |
| Odense Universitetshospital ( Site 0403) | COMPLETED | Odense | Syddanmark | 5000 | Denmark | Details |
| North Estonia Medical Centre Foundation ( Site 0081) | RECRUITING | Tallin | Harjumaa | 13419 | Estonia | Details |
| Tartu University Hospital ( Site 0079) | RECRUITING | Tartu | Tartumaa | 51014 | Estonia | Details |
| Institut Sainte Catherine ( Site 0121) | RECRUITING | Avignon | Provence-Alpes-Cote-d Azur | 84918 | France | Details |
| CHU Amiens Picardie Site Sud Amiens ( Site 0123) | RECRUITING | Amiens | Somme | 80000 | France | Details |
| Institut Curie ( Site 0112) | RECRUITING | Paris | 75005 | France | Details | |
| A.P.H. Paris. Hopital Bichat Claude Bernard ( Site 0115) | RECRUITING | Paris | 75018 | France | Details | |
| Centro de Investigaciones Clinicas de Latinoamerica S.A. - CELAN ( Site 0146) | RECRUITING | Guatemala | 01010 | Guatemala | Details | |
| Oncomedica ( Site 0145) | RECRUITING | Guatemala | 01010 | Guatemala | Details | |
| Grupo Medico Angeles ( Site 0143) | RECRUITING | Guatemala | 01015 | Guatemala | Details | |
| Medi-K Cayala ( Site 0142) | RECRUITING | Guatemala | 01016 | Guatemala | Details | |
| Centro Medico Integral De Cancerología (CEMIC) ( Site 0144) | RECRUITING | Quetzaltenango | 09002 | Guatemala | Details | |
| Bacs-Kiskun Megyei Korhaz-Onkoradiologiai Kozpont ( Site 0095) | RECRUITING | Kecskemét | Bacs-Kiskun | 6000 | Hungary | Details |
| BAZ Megyei Korhaz. Klinikai Onkologia es Sugarterapias Centrum ( Site 0092) | RECRUITING | Miskolc | Borsod-Abauj-Zemplen | 3526 | Hungary | Details |
| Petz Aladar Megyei Oktato Korhaz ( Site 0099) | RECRUITING | Gyor | Gyor-Moson-Sopron | 9024 | Hungary | Details |
| Debreceni Egyetem Klinikai Kozpont ( Site 0097) | RECRUITING | Debrecen | 4032 | Hungary | Details | |
| Somogy Megyei Kaposi Mor Oktato Korhaz ( Site 0091) | RECRUITING | Kaposvar | 7400 | Hungary | Details | |
| Soroka Medical Center-Oncology ( Site 7031) | RECRUITING | Be'er Sheva | 8400000 | Israel | Details | |
| Rambam Health Care Campus-Oncology Division ( Site 0088) | RECRUITING | Haifa | 3109601 | Israel | Details | |
| Hadassah Medical Center. Ein Kerem ( Site 0086) | RECRUITING | Jerusalem | 9112001 | Israel | Details | |
| Rabin Medical Center ( Site 7032) | RECRUITING | Petah Tikva | 4941492 | Israel | Details | |
| Chaim Sheba Medical Center ( Site 0087) | RECRUITING | Ramat Gan | 5262000 | Israel | Details | |
| Sourasky Medical Center ( Site 0089) | RECRUITING | Tel Aviv | 6423906 | Israel | Details | |
| Fondazione Policlinico Universitario Campus Bio-Medico-Radiation Oncology ( Site 7041) | COMPLETED | Roma | Lazio | 00128 | Italy | Details |
| Ospedale San Raffaele ( Site 0194) | RECRUITING | Milano | Lombardia | 20132 | Italy | Details |
| IRCCS Giovanni Paolo II. Ospedale Oncologico ( Site 0193) | RECRUITING | Bari | Puglia | 70124 | Italy | Details |
| AOU Careggi ( Site 0191) | RECRUITING | Firenze | 50134 | Italy | Details | |
| Ospedale Civile di Macerata ( Site 0190) | RECRUITING | Macerata | 62100 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0186) | RECRUITING | Milano | 20133 | Italy | Details | |
| Azienda Ospedaliero - Universitaria Policlinico di Modena ( Site 0188) | COMPLETED | Modena | 41124 | Italy | Details | |
| Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 0192) | RECRUITING | Napoli | 80131 | Italy | Details | |
| Hirosaki University Hospital ( Site 0602) | RECRUITING | Hirosaki | Aomori | 036-8563 | Japan | Details |
| University of Tsukuba Hospital ( Site 0605) | RECRUITING | Tsukuba | Ibaraki | 305-8576 | Japan | Details |
| Osaka Medical and Pharmaceutical University Hospital ( Site 0604) | RECRUITING | Takatsuki | Osaka | 5698686 | Japan | Details |
| Nagasaki University Hospital ( Site 0600) | ACTIVE_NOT_RECRUITING | Nagasaki | 852-8501 | Japan | Details | |
| Tokyo Medical and Dental University Hospital ( Site 0601) | RECRUITING | Tokyo | 113-8519 | Japan | Details | |
| Tokyo Metropolitan Komagome Hospital ( Site 0606) | RECRUITING | Tokyo | 113-8677 | Japan | Details | |
| National Cancer Center ( Site 0202) | RECRUITING | Gyeonggi-do | Kyonggi-do | 10408 | Korea, Republic of | Details |
| Seoul National University Bundang Hospital ( Site 0204) | RECRUITING | Seongnam-si | Kyonggi-do | 13620 | Korea, Republic of | Details |
| Asan Medical Center ( Site 0200) | RECRUITING | Songpagu | Seoul | 05505 | Korea, Republic of | Details |
| Chungnam National University Hospital ( Site 0203) | RECRUITING | Daejeon | Taejon-Kwangyokshi | 35015 | Korea, Republic of | Details |
| Korea University Anam Hospital ( Site 0205) | COMPLETED | Seoul | 02841 | Korea, Republic of | Details | |
| Severance Hospital Yonsei University Health System ( Site 0201) | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Pauls Stradins Clinical University Hospital ( Site 0073) | RECRUITING | Riga | LV1002 | Latvia | Details | |
| Hospital Universiti Sains Malaysia ( Site 0237) | RECRUITING | Kubang Kerian | Kelantan | 16150 | Malaysia | Details |
| Hospital Pulau Pinang ( Site 0239) | RECRUITING | Penang | Pulau Pinang | 10990 | Malaysia | Details |
| Hospital Kuala Lumpur ( Site 0238) | COMPLETED | Kuala Lumpur | 50586 | Malaysia | Details | |
| University Malaya Medical Centre ( Site 0236) | RECRUITING | Kuala Lumpur | 59100 | Malaysia | Details | |
| Netherlands Cancer Institute (NKI) ( Site 0183) | RECRUITING | Amsterdam | Noord-Holland | 1066 CX | Netherlands | Details |
| Erasmus MC ( Site 0182) | RECRUITING | Rotterdam | Zuid-Holland | 3015 GD | Netherlands | Details |
| Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie ( Site 0153) | RECRUITING | Krakow | Malopolskie | 31-826 | Poland | Details |
| Mazowiecki Szpital Wojewódzki w Siedlcach ( Site 0154) | RECRUITING | Siedlce | Mazowieckie | 08-110 | Poland | Details |
| Szpital Wojewodzki im. Mikolaja Kopernika ( Site 0152) | RECRUITING | Koszalin | Zachodniopomorskie | 75-581 | Poland | Details |
| Hospital Beatriz Angelo ( Site 0303) | RECRUITING | Loures | Lisboa | 2674-514 | Portugal | Details |
| Centro Hospitalar e Universitario de Coimbra ( Site 0306) | RECRUITING | Coimbra | 3000-075 | Portugal | Details | |
| CHLO, EPE - Hospital de Sao Francisco Xavier ( Site 0302) | RECRUITING | Lisboa | 1449-005 | Portugal | Details | |
| Centro Hospitalar Lisboa Norte EPE - Hospital de Santa Maria ( Site 0305) | RECRUITING | Lisboa | 1649-035 | Portugal | Details | |
| Advance Urology and Laparoscopic Center ( Site 0281) | RECRUITING | Ponce | 00716 | Puerto Rico | Details | |
| PAN American Center Oncologic ( Site 0280) | RECRUITING | San Juan, Rio Piedras | 00935 | Puerto Rico | Details | |
| Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 0249) | RECRUITING | Cluj Napoca | Cluj | 400015 | Romania | Details |
| S.C. Radiotherapy Center Cluj S.R.L ( Site 0252) | RECRUITING | Cluj-Napoca | Cluj | 407280 | Romania | Details |
| S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 0248) | RECRUITING | Craiova | Dolj | 200542 | Romania | Details |
| Policlinica Oncomed SRL ( Site 0254) | RECRUITING | Timisoara | Timis | 300239 | Romania | Details |
| S.C.Focus Lab Plus S.R.L ( Site 0253) | RECRUITING | Bucuresti | 022548 | Romania | Details | |
| Institutul Oncologic-Oncologie Medicala ( Site 0256) | RECRUITING | Cluj | 400015 | Romania | Details | |
| Institutul Regional de Oncologie Iasi ( Site 0255) | COMPLETED | Iasi | 700483 | Romania | Details | |
| Instituto Catalan de Oncologia - ICO ( Site 0103) | RECRUITING | L Hospitalet De Llobregat | Barcelona | 08908 | Spain | Details |
| Hospital La Fe de Valencia ( Site 0105) | RECRUITING | Valencia | Valenciana, Comunitat | 46026 | Spain | Details |
| HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 0106) | RECRUITING | Sevilla | 41013 | Spain | Details | |
| Chi Mei Medical Center ( Site 0215) | RECRUITING | Tainan City | Tainan | 71004 | Taiwan | Details |
| Kaohsiung Chang Gung Memorial Hospital ( Site 0209) | RECRUITING | Kaohsiung | 83301 | Taiwan | Details | |
| Taichung Veterans General Hospital ( Site 0213) | RECRUITING | Taichung | 407 | Taiwan | Details | |
| National Cheng Kung University Hospital ( Site 0208) | COMPLETED | Tainan | 70403 | Taiwan | Details | |
| National Taiwan University Hospital ( Site 0210) | RECRUITING | Taipei | 10002 | Taiwan | Details | |
| Taipei Veterans General Hospital ( Site 0211) | RECRUITING | Taipei | 112 | Taiwan | Details | |
| Chang Gung Medical Foundation.Linkou Branch ( Site 0212) | RECRUITING | Taoyuan | 333 | Taiwan | Details | |
| University of Health Sciences,Gulhane School of Medicine-Oncology ( Site 0509) | RECRUITING | Ankara | 06010 | Turkey | Details | |
| Ankara Universitesi Tip Fakultesi. ( Site 0502) | RECRUITING | Ankara | 06100 | Turkey | Details | |
| Istanbul Uni. Cerrahpasa Tip Fakultesi ( Site 0501) | RECRUITING | Istanbul | 34098 | Turkey | Details | |
| T.C. Saglik Bakanligi Turkiye Kamu Hastaneleri Kurumu - Baki-Istanbul Bakirkoy Sadi Konuk Training ( | RECRUITING | Istanbul | 34147 | Turkey | Details | |
| Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 0504) | RECRUITING | Istanbul | 34722 | Turkey | Details | |
| Ege University Medical Faculty ( Site 0508) | RECRUITING | Izmir | 35100 | Turkey | Details | |
| Karadeniz Teknik Universitesi Tip Fakultesi ( Site 0503) | RECRUITING | Trabzon | 61080 | Turkey | Details | |
| Clinical oncology dispensary of Dnipro ( Site 0133) | SUSPENDED | Dnipro | Dnipropetrovska Oblast | 49055 | Ukraine | Details |
| Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 0139) | SUSPENDED | Kharkiv | Kharkivska Oblast | 61024 | Ukraine | Details |
| MNPE Regional Center of Oncology ( Site 0134) | SUSPENDED | Kharkiv | Kharkivska Oblast | 61070 | Ukraine | Details |
| Ukranian Center of TomoTherapy ( Site 0140) | SUSPENDED | Kropyvnytskiy | Kirovohradska Oblast | 25011 | Ukraine | Details |
| SNPE National Cancer Institute ( Site 0136) | SUSPENDED | Kyiv | Kyivska Oblast | 03022 | Ukraine | Details |
| Kyiv City Clinical Oncology Center ( Site 0135) | SUSPENDED | Kyiv | 03115 | Ukraine | Details | |
| Betsi Cadwaladr University Health Board ( Site 0447) | COMPLETED | Rhyl | Denbighshire | LL18 5UJ | United Kingdom | Details |
| South Devon Healthcare Foundation Trust. Torbay Hospital ( Site 0444) | RECRUITING | Torquay | Devon | TQ2 7AA | United Kingdom | Details |
| Royal Preston Hospital ( Site 0449) | RECRUITING | Preston | Lancashire | PR2 9HT | United Kingdom | Details |
| University College London Hospitals NHS Foundation Trust ( Site 0445) | RECRUITING | London | London, City Of | NW1 2PG | United Kingdom | Details |
| The Royal Marsden NHS Foundation Trust. ( Site 0442) | RECRUITING | London | London, City Of | SW3 6JJ | United Kingdom | Details |
| Nottingham University Hospital NHS Trust ( Site 0250) | COMPLETED | Nottingham | Nottinghamshire | NG5 1PB | United Kingdom | Details |
| Darlington Memorial Hospital NHS Trust ( Site 0446) | RECRUITING | Darlington | DL3 6HX | United Kingdom | Details |