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| NCT ID | NCT04486378 |
| Title | A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | BioNTech RNA Pharmaceuticals GmbH |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | GBR | ESP | DEU | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic - Scottsdale | RECRUITING | Scottsdale | Arizona | 85259 | United States | Details |
| John Muir Clinical Research Center | RECRUITING | Concord | California | 94520 | United States | Details |
| The Oncology Institute of Hope and Innovation | RECRUITING | Glendale | California | 91204 | United States | Details |
| Marin Cancer Care | RECRUITING | Greenbrae | California | 94904 | United States | Details |
| St Joseph Hospital of Orange | RECRUITING | Orange | California | 92868 | United States | Details |
| Sansum Clinic | RECRUITING | Santa Barbara | California | 93105 | United States | Details |
| Rocky Mountain Cancer Centers - Denver Midtwon | RECRUITING | Denver | Colorado | 80218 | United States | Details |
| Florida Cancer Specialist South | RECRUITING | Fort Myers | Florida | 33916 | United States | Details |
| Mayo Clinic Florida | RECRUITING | Jacksonville | Florida | 32224 | United States | Details |
| Florida Cancer Specialists | WITHDRAWN | West Palm Beach | Florida | 33401 | United States | Details |
| Cancer Care Center of Decatur, Cancer Care Specialists of IL | RECRUITING | Decatur | Illinois | 62526 | United States | Details |
| Indiana University Melvin and Bren Simon Comprehensive Cancer | RECRUITING | Indianapolis | Indiana | 46202 | United States | Details |
| University of Kansas Cancer Center | RECRUITING | Westwood | Kansas | 66205 | United States | Details |
| University of Louisville - James Graham Brown Cancer Center | RECRUITING | Louisville | Kentucky | 40202 | United States | Details |
| Josephine Ford Cancer Center-Henry Ford Cancer Center | RECRUITING | Detroit | Michigan | 48202 | United States | Details |
| New York Oncology Hematology, P.C. | RECRUITING | Albany | New York | 12206 | United States | Details |
| Weill Cornell Medical College | RECRUITING | New York | New York | 10021 | United States | Details |
| New York - Presbyterian Hospital - Columbia University Medical center | RECRUITING | New York | New York | 10032 | United States | Details |
| Mayo Clinic Rochester | RECRUITING | Rochester | New York | 55905 | United States | Details |
| Oncology Hematology Care Clinical Trials | RECRUITING | Cincinnati | Ohio | 45245 | United States | Details |
| Willamette Valley Cancer Institute and Research Center | RECRUITING | Eugene | Oregon | 97401 | United States | Details |
| Rhode Island Hospital | RECRUITING | Providence | Rhode Island | 02906 | United States | Details |
| Hollings Cancer Center Medical University Of South Carolina | RECRUITING | Charleston | South Carolina | 29425 | United States | Details |
| Sarah Cannon (Tennessee Oncology - Nashville | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Texas Oncology, P.A. - Austin | RECRUITING | Austin | Texas | 78705 | United States | Details |
| Texas Oncology-Baylor Charles A. Sammons Cancer Center | RECRUITING | Dallas | Texas | 75246 | United States | Details |
| The University of Texas MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Texas Oncology-San Antonio Medical Center | RECRUITING | San Antonio | Texas | 78240 | United States | Details |
| Texas Oncology - Northeast Texas | RECRUITING | Tyler | Texas | 75702 | United States | Details |
| Virginia Cancer Specialists | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| Benaroya Research Institute at Virginia Mason | RECRUITING | Seattle | Washington | 98101 | United States | Details |
| University of Washington | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| MultiCare Institute for Research & Innovation | RECRUITING | Spokane | Washington | 99218 | United States | Details |
| Northwest Cancer Specialists P.C. | RECRUITING | Vancouver | Washington | 98684 | United States | Details |
| University of Wisconsin Carbone Cancer Center | RECRUITING | Madison | Wisconsin | 53792 | United States | Details |
| Froedtert Hospital and Medical College of Wisconsin | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Imeldaziekenhuis General Hospital | RECRUITING | Bonheiden | 2820 | Belgium | Details | |
| VZW Algemeen Ziekenhuis AZ Klina | RECRUITING | Brasschaat | 2930 | Belgium | Details | |
| Institut Jules Bordet | WITHDRAWN | Brussel | 1070 | Belgium | Details | |
| GHDC (Grand Hopital de Charleroi) | RECRUITING | Charleroi | 6000 | Belgium | Details | |
| AZ Groeninge | RECRUITING | Kortrijk | 8500 | Belgium | Details | |
| Centres Hospitaliers Jolimont | RECRUITING | La Louviere | 7100 | Belgium | Details | |
| Universitaire Ziekenhuizen Leuven | RECRUITING | Leuven | 3000 | Belgium | Details | |
| AZ Delta Roeselare | RECRUITING | Roeselare | 8800 | Belgium | Details | |
| GasthuisZusters Antwerpen - Sint-Augustinus | RECRUITING | Wilrijk | 2610 | Belgium | Details | |
| Universite Catholique de Louvain (UCL) - Cliniques Universitaires Saint-Luc | RECRUITING | Woluwe-Saint-Lambert | 1200 | Belgium | Details | |
| Charité - Universitätsmedizin Berlin | RECRUITING | Berlin | 10117 | Germany | Details | |
| Universitaetsklinikum St. Josef-Hospital Bochum | RECRUITING | Bochum | 44791 | Germany | Details | |
| Universitätsklinikum Bonn, Med. Klinik u. Poliklinik I | RECRUITING | Bonn | 53105 | Germany | Details | |
| Klinikum Esslingen GmbH | RECRUITING | Esslingen | 73730 | Germany | Details | |
| Krankenhaus Nordwest GmbH - Institut Fuer Klinisch-Onkologische Forschung (IKF) | RECRUITING | Frankfurt am Main | 60488 | Germany | Details | |
| Klinikum der Johann Wolfgang Goethe-Universitaet Frankfurt | RECRUITING | Frankfurt am Main | 60590 | Germany | Details | |
| Studiengesellschaft BSF | RECRUITING | Halle | 06108 | Germany | Details | |
| Universitätsklinikum Hamburg-Eppendorf | RECRUITING | Hamburg | 20246 | Germany | Details | |
| Hämatologisch-Onkologische Praxis Eppendorf | RECRUITING | Hamburg | 20249 | Germany | Details | |
| Asklepios Klinik Altona | RECRUITING | Hamburg | 22763 | Germany | Details | |
| Medizinische Hochschule Hannover | RECRUITING | Hannover | 30625 | Germany | Details | |
| National Center for Tumor Diseases (NCT) Heidelberg | RECRUITING | Heidelberg | 69120 | Germany | Details | |
| SLK-Kliniken Heilbronn GmbH | RECRUITING | Heilbronn | 74078 | Germany | Details | |
| Staedtisches Krankenhaus Kiel gGmbH | RECRUITING | Kiel | 24116 | Germany | Details | |
| Universitaetsklinikum Leipzig AoeR | RECRUITING | Leipzig | 04103 | Germany | Details | |
| Universitaetsmedizin der Johannes Gutenberg Universitaet Mainz KoeR | RECRUITING | Mainz | 55131 | Germany | Details | |
| Klinikum der Philipps-Universität Marburg | RECRUITING | Marburg | 35043 | Germany | Details | |
| LMU Klinikum (Campus Großhadern) Medizinische Klinik Universität München | RECRUITING | München | 81377 | Germany | Details | |
| Städtisches Klinikum München GmbH, Klinikum Neuperlach | RECRUITING | München | 81737 | Germany | Details | |
| OhO Ostholstein Onkologie | RECRUITING | Oldenburg In Holstein | 23758 | Germany | Details | |
| Prosper Hospital | RECRUITING | Recklinghausen | 45659 | Germany | Details | |
| Robert-Bosch-Krankenhaus - Centrum fuer Tumorerkrankungen | RECRUITING | Stuttgart | 70376 | Germany | Details | |
| Universitätsklinikum Ulm | RECRUITING | Ulm | 89081 | Germany | Details | |
| Universitätsklinikum Würzburg | RECRUITING | Würzburg | 97080 | Germany | Details | |
| Complejo Hospitalario Universitario A Coruna | RECRUITING | A Coruna | 15006 | Spain | Details | |
| Hospital Nuestra Senora de Sonsoles | RECRUITING | Avila | 05004 | Spain | Details | |
| Hospital Universitari Germans Trias - ICO Badalona | RECRUITING | Badalona | 08916 | Spain | Details | |
| Hospital Universitari Vall d'Hebron | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Institut Clinic Hematolo/Oncologia- ICMHO, Hospital Clinic i Provincial de Barcelona | RECRUITING | Barcelona | 8036 | Spain | Details | |
| Hospital de la Santa Creu i Sant Pau | RECRUITING | Barcelona | 8041 | Spain | Details | |
| Hospital Universitario Reina Sofia | RECRUITING | Cordoba | 14004 | Spain | Details | |
| Hospital General Universitario Gregorio Maranon | RECRUITING | Madrid | 28007 | Spain | Details | |
| Clinica Universidad Navarra | RECRUITING | Madrid | 28027 | Spain | Details | |
| Hospital Universitario Ramón y Cajal | RECRUITING | Madrid | 28034 | Spain | Details | |
| Hospital Clinico San Carlos | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital Universitario Fundacion Jimenez Diaz | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital Universitario La Paz | RECRUITING | Madrid | 28046 | Spain | Details | |
| Hospital Universitario HMN Sanchinarro, Centro Integral Oncologico Clara Campal (CIOCC) | RECRUITING | Madrid | 28050 | Spain | Details | |
| Hospital Universitario Puerta de Hierro de Majadahonda | RECRUITING | Majadahonda | 28222 | Spain | Details | |
| Hospital Regional Universitario Carlos Haya Malaga - Instituto de Investigacion Biomedica de Malaga | RECRUITING | Málaga | 29011 | Spain | Details | |
| Complejo Hospitalario de Orense | RECRUITING | Orense | 32005 | Spain | Details | |
| Clinica Universitaria de Navarra | RECRUITING | Pamplona | 31008 | Spain | Details | |
| Complejo Hospitalario de Navarra (CHN) | RECRUITING | Pamplona | 31008 | Spain | Details | |
| Hospital Universitario Marques De Valdecilla | RECRUITING | Santander | 39008 | Spain | Details | |
| Complejo Hospitalario Universitario De Santiago De Compostela | RECRUITING | Santiago De Compostela | 15706 | Spain | Details | |
| Hospital Universitario Virgen del Rocio - Hospital de la Mujer | RECRUITING | Sevilla | 41013 | Spain | Details | |
| Consorcio Hospital General Valencia | RECRUITING | Valencia | 46014 | Spain | Details | |
| Complexo Hospitalario Universitario de Vigo (CHUVI) | RECRUITING | Vigo | 36312 | Spain | Details | |
| Hospital Universitario Miguel Servet | RECRUITING | Zaragoza | 50009 | Spain | Details | |
| Lunds Universitet - Medicinska Fakulteten (Lund University Faculty of Medicine) | RECRUITING | Lund | 221 00 | Sweden | Details | |
| Sodersjukhuset, Onkologiska Kliniken | RECRUITING | Stockholm | 11883 | Sweden | Details | |
| Karolinska Universitetssjukhuset Solna | RECRUITING | Stockholm | 17176 | Sweden | Details | |
| The Clatterbridge Cancer Centre NHS Foundation Trust | RECRUITING | Bebington | CH63 4JY | United Kingdom | Details | |
| Queen Elizabeth Hospital Birmingham-University Hospitals Birmingham NHS Foundation Trust | RECRUITING | Birmingham | B15 2GW | United Kingdom | Details | |
| Velindre NHS Trust, Velindre Cancer Centre | RECRUITING | Cardiff | CF14 2TL | United Kingdom | Details | |
| Beatson West of Scotland Cancer Centre - Gartnavel Royal Hospital - NHS Greater Glasgow and Clyde | RECRUITING | Glasgow | G12 0XH | United Kingdom | Details | |
| St Bartholomew's Hospital-Barts Health NHS Trust | RECRUITING | London | EC1A 7BE | United Kingdom | Details | |
| University College London Hospitals NHS Foundation Trust | RECRUITING | London | NW2 1PG | United Kingdom | Details | |
| Royal Free London NHS Foundation Trust | RECRUITING | London | NW3 2QG | United Kingdom | Details | |
| Guy's and St Thomas' Hospital NHS Foundation Trust | RECRUITING | London | SE1 7EH | United Kingdom | Details | |
| The Royal Marsden NHS Foundation Trust- Chelsea | RECRUITING | London | SW3 6JJ | United Kingdom | Details | |
| The Christie NHS Foundation Trust | RECRUITING | Manchester | M20 4BX | United Kingdom | Details | |
| The Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital | RECRUITING | Newcastle Upon Tyne | NE7 7DN | United Kingdom | Details | |
| Royal Preston Hospital - Lancashire Teaching Hospitals NHS Foundation Trust | RECRUITING | Preston | PR2 9HT | United Kingdom | Details | |
| The Royal Marsden NHS Foundation Trust | RECRUITING | Sutton | SM25NG | United Kingdom | Details | |
| Torbay Hospital - South Devon Healthcare Nhs Foundation Trust, Lowes Bridge | RECRUITING | Torquay | TQ2 7AA | United Kingdom | Details |